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51

Prevalence and prognostic and predictive relevance of PRAME in breast cancer

Padraig Doolan, Martin Clynes, Susan Kennedy, Jai Prakash Mehta, John Crown, Lorraine O’Driscoll

Journal:

Breast Cancer Research and Treatment

Year:

2008

Language:

english

File:

PDF, 252 KB

english, 2008

52

Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue

Vanesa Martinez, Susan Kennedy, Padraig Doolan, Patrick Gammell, Helena Joyce, Elaine Kenny, Jai Prakash Mehta, Eoin Ryan, Robert O’Connor, John Crown, Martin Clynes, Lorraine O’Driscoll

Journal:

Breast Cancer Research and Treatment

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

53

The role of recombinant proteins in the development of serum-free media

Joanne Keenan, Dermot Pearson, Martin Clynes

Journal:

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

54

Proliferation control strategies to improve productivity and survival during CHO based production culture

Niraj Kumar, Patrick Gammell, Martin Clynes

Journal:

Year:

2007

Language:

english

File:

PDF, 240 KB

english, 2007

55

Detection and cloning of LINE-1 elements in CHO cells

Olga Piskareva, Martin Clynes, Niall Barron

Journal:

Year:

2007

Language:

english

File:

PDF, 191 KB

english, 2007

56

Editorial

Donnacha O’Driscoll, Patrick Gammell, Martin Clynes

Journal:

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

57

Detection and cloning of LINE-1 elements in CHO cells

Olga Piskareva, Martin Clynes, Niall Barron

Journal:

Year:

2007

Language:

english

File:

PDF, 94 KB

english, 2007

58

Limbal stem cells, a review of their identification and culture for clinical use

Finbarr O’Sullivan, Martin Clynes

Journal:

Year:

2007

Language:

english

File:

PDF, 150 KB

english, 2007

59

Modulation of P-gp expression by lapatinib

Gráinne Dunne, Laura Breen, Denis M. Collins, Sandra Roche, Martin Clynes, Robert O’Connor

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

60

Imatinib and docetaxel in combination can effectively inhibit glioma invasion in an in vitro 3D invasion assay

Paula Kinsella, Martin Clynes, Verena Amberger-Murphy

Journal:

Journal of Neuro-Oncology

Year:

2011

Language:

english

File:

PDF, 655 KB

english, 2011

61

Transcriptional Profiling of Gene Expression Changes in a PACE-Transfected CHO DUKX Cell Line Secreting High Levels of rhBMP-2

Padraig Doolan, Mark Melville, Patrick Gammell, Martin Sinacore, Paula Meleady, Kevin McCarthy, Linda Francullo, Mark Leonard, Timothy Charlebois, Martin Clynes

Journal:

Molecular Biotechnology

Year:

2008

Language:

english

File:

PDF, 430 KB

english, 2008

62

Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides

David Bergin, Lisa Murphy, Joanne Keenan, Martin Clynes, Kevin Kavanagh

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 326 KB

english, 2006

63

Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry

Niraj Kumar, Priyanka Maurya, Patrick Gammell, Paul Dowling, Martin Clynes, Paula Meleady

Journal:

Biotechnology Progress

Year:

2008

Language:

english

File:

PDF, 346 KB

english, 2008

64

Culture filtrates ofAspergillus fumigatusinduce different modes of cell death in human cancer cell lines

Paul Daly, Steven Verhaegen, Martin Clynes, Kevin Kavanagh

Journal:

Year:

1999

Language:

english

File:

PDF, 183 KB

english, 1999

65

Introduction

Journal:

Year:

1998

Language:

english

File:

PDF, 6 KB

english, 1998

66

Use of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistance

Daragh Byrne, Carmel Daly, Roisin NicAmhlaoibh, Anthony Howlett, Kevin Scanlon, Martin Clynes

Journal:

Year:

1998

Language:

english

File:

PDF, 174 KB

english, 1998

67

Regulation of keratin and integrin gene expression in cancer and drug resistance

Noel Daly, Paula Meleady, Derek Walsh, Martin Clynes

Journal:

Year:

1998

Language:

english

File:

PDF, 177 KB

english, 1998

68

Microarray expression profiling identifies genes regulating sustained cell specific productivity (S-Qp) in CHO K1 production cell lines

Dr. Padraig Doolan, Niall Barron, Paula Kinsella, Colin Clarke, Paula Meleady, Finbarr O'Sullivan, Mark Melville, Mark Leonard, Martin Clynes

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 586 KB

english, 2012

69

CGCDB: A web-based resource for the investigation of gene coexpression in CHO cell culture

Colin Clarke, Padraig Doolan, Niall Barron, Paula Meleady, Stephen F. Madden, Dana DiNino, Mark Leonard, Martin Clynes

Journal:

Biotechnology and Bioengineering

Year:

2012

Language:

english

File:

PDF, 183 KB

english, 2012

70

Biochemical relapse following radical prostatectomy and miR-200a levels in prostate cancer

Niall Barron, Joanne Keenan, Patrick Gammell, Vanesa G. Martinez, Alex Freeman, John R. Masters, Martin Clynes

Journal:

Year:

2012

Language:

english

File:

PDF, 331 KB

english, 2012

71

Separation of viable from nonviable cells using a discontinuous density gradient

Martin M. Clynes, Honor Smyth, Richard O’Kennedy, Antonia Corrigan

Journal:

In Vitro Cellular & Developmental Biology - Plant

Year:

1980

Language:

english

File:

PDF, 286 KB

english, 1980

72

Acid phosphatase: Endpoint for in vitro toxicity tests

Angela Martin, Martin Clynes

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1991

Language:

english

File:

PDF, 198 KB

english, 1991

73

Production of autostimulatory growth factors by the human carcinoma line, RPMI 2650

Breda M. Carey, Margaret Dooley, Roisin Weedle, Martin Clynes

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1993

Language:

english

File:

PDF, 762 KB

english, 1993

74

Cellular models for multiple drug resistance in cancer

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

75

Re: Sialic acid in T. B and CLL lymphocytes

Richard O'Kennedy, Honor Smyth, Antonia Corrigan, Martin Clynes

Journal:

Leukemia Research

Year:

1982

Language:

english

File:

PDF, 56 KB

english, 1982

76

Monoclonal antibody 5C3 raised against formalin fixed paraffin-embedded invasive breast tumour tissue: Characterisation of its reactive antigen via immunoprecipitation and internal sequencing

Annemarie Larkin, Elizabeth Moran, Susan M. Kennedy, Martin Clynes

Journal:

Journal of Immunological Methods

Year:

2005

Language:

english

File:

PDF, 2.48 MB

english, 2005

77

Detecting de novo insulin synthesis in embryonic stem cell-derived populations

Eadaoin Mc Kiernan, Niall W. Barron, Finbarr O'Sullivan, Paul Barham, Martin Clynes, Lorraine O'Driscoll

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

78

Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line

Joanne Keenan, Helena Joyce, Sinead Aherne, Shirley O'Dea, Padraig Doolan, Vincent Lynch, Martin Clynes

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

79

Characterization and response of newly developed high-grade glioma cultures to the tyrosine kinase inhibitors, erlotinib, gefitinib and imatinib

Paula Kinsella, Rachel Howley, Padraig Doolan, Colin Clarke, Stephen F. Madden, Martin Clynes, Michael Farrell, Verena Amberger-Murphy

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 775 KB

english, 2012

80

Monoclonal antibodies raised to paraffin wax embedded archival tissue; feasibility study of their potential to detect novel antigenic markers

Elizabeth Moran, Annemarie Larkin, Irene Cleary, Colma Barnes, Susan M Kennedy, Peter Kelehan, Martin Clynes

Journal:

Journal of Immunological Methods

Year:

1998

Language:

english

File:

PDF, 2.55 MB

english, 1998

81

Challenges in molecular analysis for individualized cancer therapy

Martin Clynes, Robert O'Connor, Lorraine O'Driscoll, Carmel Daly, Paula Meleady

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 25 KB

english, 2003

82

Bromodeoxyuridine induces keratin protein synthesis at a posttranscriptional level in human lung tumour cell lines

Shirley McBride, Derek Walsh, Paula Meleady, Noel Daly, Martin Clynes

Journal:

Differentiation

Year:

1999

Language:

english

File:

PDF, 526 KB

english, 1999

83

Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines

Derek Walsh, Paula Meleady, Brendan Power, Simon J. Morley, Martin Clynes

Journal:

Differentiation

Year:

2003

Language:

english

File:

PDF, 214 KB

english, 2003

84

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

Sharon A Glynn, Dermot O'Sullivan, Alex J Eustace, Martin Clynes, Norma O'Donovan

Journal:

Year:

2008

Language:

english

File:

PDF, 353 KB

english, 2008

85

Engineering vero cells to secrete human insulin

Lorraine O’Driscoll, Patrick Gammell, Martin Clynes

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

2002

Language:

english

File:

PDF, 1.77 MB

english, 2002

86

Progress in molecular and subcellular biology, volume 12 : Edited by P. Jeanteur, Y. Kuchino, W.E.G. Maller and P.L. Paine; Springer-Verlag; Berlin, 1991; ix + 137 pages. DM 128.00. ISBN 3-540-53900-x.

Journal:

Year:

1992

Language:

english

File:

PDF, 102 KB

english, 1992

87

Interactions among cell signalling systems (Ciba Foundation Symposium 164) : edited by R. Sato, G.R. Bock and K. Widdows, John Wiley; Chichester, 1992; xi + 268 pages. £ 42.50, $ 75.00

Journal:

Year:

1993

Language:

english

File:

PDF, 107 KB

english, 1993

88

Developmental effects of inhibitors of nucleotide metabolism in Drosophila

Martin M. Clynes, Edward J. Duke

Journal:

Journal of Insect Physiology

Year:

1976

Language:

english

File:

PDF, 807 KB

english, 1976

89

Identification of microRNAs with a role in glucose stimulated insulin secretion by expression profiling of MIN6 cells

Erica Hennessy, Martin Clynes, Per Bendix Jeppesen, Lorraine O’Driscoll

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 310 KB

english, 2010

90

Bleomycin treatment of A549 human lung cancer cells results in association of MGr1-Ag and caveolin-1 in lipid rafts

Annett Linge, Paula Meleady, Michael Henry, Martin Clynes, Michael Kasper, Kathrin Barth

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2011

Language:

english

File:

PDF, 552 KB

english, 2011

91

RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation

Naomi Walsh, AnneMarie Larkin, Niall Swan, Kevin Conlon, Paul Dowling, Ray McDermott, Martin Clynes

Journal:

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

92

Development, validation and application of a sensitive LC–MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium

Sandra Roche, Louise Sewell, Justine Meiller, Kasper Pedersen, Rajesh Rajpal, Peter O’Gorman, Martin Clynes, Robert O’Connor

Journal:

Journal of Chromatography B

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

93

Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3

Neil Macdonald, Julie P.I. Welburn, Martin E.M. Noble, Anhco Nguyen, Michael B. Yaffe, David Clynes, Jonathan G. Moggs, George Orphanides, Stuart Thomson, John W. Edmunds, Alison L. Clayton, Jane A. E

Journal:

Year:

2005

Language:

english

File:

PDF, 845 KB

english, 2005

94

Rapid and sensitive liquid chromatography–tandem mass spectrometry for the quantitation of epirubicin and identification of metabolites in biological samples

Rachel Wall, Gillian McMahon, John Crown, Martin Clynes, Robert O’Connor

Journal:

Year:

2007

Language:

english

File:

PDF, 470 KB

english, 2007

95

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes

Barry Coyle, Paula Kinsella, Malachy McCann, Michael Devereux, Robert O'Connor, Martin Clynes, Kevin Kavanagh

Journal:

Toxicology in Vitro

Year:

2004

Language:

english

File:

PDF, 276 KB

english, 2004

96

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: Possible mechanisms involved

Vanesa G. Martinez, Kaye J. Williams, Ian J. Stratford, Martin Clynes, Robert O’Connor

Journal:

Toxicology in Vitro

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

97

Development of taxane resistance in a panel of human lung cancer cell lines

Laura Breen, Lisa Murphy, Joanne Keenan, Martin Clynes

Journal:

Toxicology in Vitro

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

98

MDR1 expression is associated with adverse survival in melanoma of the uveal tract

Barbara M. Dunne, Morgan McNamara, Martin Clynes, Stephen G. Shering, Anne Marie Larkin, Elizabeth Moran, Colma Barnes, Susan M. Kennedy

Journal:

Human Pathology

Year:

1998

Language:

english

File:

PDF, 1.59 MB

english, 1998

99

Lack of prognostic significance of survivin, survivin-ΔEx3, survivin-2B, galectin-3, bag-1, bax-α and MRP-1 mRNAs in breast cancer

Lorraine O'Driscoll, Rasha Linehan, Susan M. Kennedy, Deirdre Cronin, Rachel Purcell, Sharon Glynn, Enda W. McDermott, Arnold D. Hill, Niall J. O'Higgins, Michael Parkinson, Martin Clynes

Journal:

Year:

2003

Language:

english

File:

PDF, 224 KB

english, 2003

100

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

Clarke, Colin, Henry, Michael, Doolan, Padraig, Kelly, Shane, Aherne, Sinead, Sanchez, Noelia, Kelly, Paul, Kinsella, Paula, Breen, Laura, Madden, Stephen F, Zhang, Lin, Leonard, Mark, Clynes, Martin,

Journal:

Year:

2012

Language:

english

File:

PDF, 4.71 MB

english, 2012