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51

10 New thrombolytic agents and strategies

Desire Collen, H. Roger Lijnen

Journal:

Baillière's Clinical Haematology

Year:

1995

Language:

english

File:

PDF, 920 KB

english, 1995

52

Genetic Analysis of Blood Vessel Formation: Role of Endothelial Versus Smooth Muscle Cells

Peter Carmeliet, Désiré Collen

Journal:

Trends in Cardiovascular Medicine

Year:

1997

Language:

english

File:

PDF, 3.12 MB

english, 1997

53

Identification and Some Properties of a New Fast-Reacting Plasmin Inhibitor in Human Plasma

Désiré COLLEN

Journal:

Year:

1976

Language:

english

File:

PDF, 720 KB

english, 1976

54

On the Kinetics of the Reaction between Human Antiplasmin and Plasmin

Björn WIMAN, Désiré COLLEN

Journal:

Year:

1978

Language:

english

File:

PDF, 516 KB

english, 1978

55

Purification and Cahracterization of Bovine Coagulation Factor XII (Hageman Factor)

Hadrilk CLAEYS, Désiré COLLEN

Journal:

Year:

1978

Language:

english

File:

PDF, 592 KB

english, 1978

56

On the Kinetics of the Reaction between Human Antiplasmin and a Low-Molecular-Weight Form of Plasmin

Björn WIMAN, Lars BOMAN, Désiré COLLEN

Journal:

Year:

1978

Language:

english

File:

PDF, 356 KB

english, 1978

57

Kinetics of the Reactions between Streptokinase, Plasmin and α2-Antiplasmin

Stewart A. CEDERHOLM-WILLIAMS, Frans DE COCK, Henri R. LIJNEN, Désiré COLLEN

Journal:

Year:

1979

Language:

english

File:

PDF, 759 KB

english, 1979

58

On the Rolw of the Carbohydrate Side Chains of Human Plasminogen in Its Interaction with α2-Antiplasmin and Fibrin

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1981

Language:

english

File:

PDF, 666 KB

english, 1981

59

Messenger RNA for Human Tissue Plasminogen Activator

Ghislain OPDENAKKER, Hans WEENING, Désiré COLLEN, Alfons BILLIAU, Piet DE SOMER

Journal:

Year:

1982

Language:

english

File:

PDF, 642 KB

english, 1982

60

Influence of cyanogen-bromide-digested fibrinogen on the kinetics of plasminogen activation by urokinase

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1984

Language:

english

File:

PDF, 438 KB

english, 1984

61

Characterization of the high-affinity interaction between human plasminogen and pro-urokinase

H. Roger LIJNEN, Concepcion ZAMARRON, Désiré COLLEN

Journal:

Year:

1985

Language:

english

File:

PDF, 380 KB

english, 1985

62

A monoclonal antibody directed against the high-affinity lysine-binding site (LBS) of human plasminogen : Role of LBS in the regulation of fibrinolysis

Paul HOLVOET, Henri Roger LIJNEN, Désiré COLLEN

Journal:

Year:

1986

Language:

english

File:

PDF, 560 KB

english, 1986

63

Characterization of functional domains in human tissue-type plasminogen activator with the use of monoclonal antibodies

Paul HOLVOET, Henri Roger LIJNEN, Désiré COLLEN

Journal:

Year:

1986

Language:

english

File:

PDF, 668 KB

english, 1986

64

Differential reactivity of Glu-Gly-Arg-CH2Cl, a synthetic urokinase inhibitor, with single-chain and two-chain forms of urokinase-type plasminogen activator

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1987

Language:

english

File:

PDF, 540 KB

english, 1987

65

Amino-acid sequence of human α2-antiplasmin

H. Roger LIJNEN, William E. HOLMES, Berthe VAN HOEF, Björn WIMAN, Henri RODRIGUEZ, Désiré COLLEN

Journal:

Year:

1987

Language:

english

File:

PDF, 969 KB

english, 1987

66

Activation with plasmin of two-chain urokinase-type plasminogen activator derived from single-chain urokinase-type plasminogen activator by treatment with thrombin

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1987

Language:

english

File:

PDF, 614 KB

english, 1987

67

Enzymatic properties of single-chain and two-chain forms of a Lys158→ Glu158 mutant of urokinase–type plasminogen activator

H. Roger LIJNEN, Berthe VAN HOEF, Luc NELLES, William E. HOLMES, Désiré COLLEN

Journal:

Year:

1988

Language:

english

File:

PDF, 343 KB

english, 1988

68

Purification and characterization of natural and recombinant human plasminogen activator inhibitor-1 (PAI-1)

Marie Christine ALESSI, Paul J. DECLERCK, Maria DE MOL, Luc NELLES, Désiré COLLEN

Journal:

Year:

1988

Language:

english

File:

PDF, 1.38 MB

english, 1988

69

Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160

H. Roger LIJNEN, Luc NELLES, Berthe VAN HOEF, Eddy DEMARSIN, Désiré COLLEN

Journal:

Year:

1988

Language:

english

File:

PDF, 962 KB

english, 1988

70

Biochemical properties of conjugates of urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin

Maria DEWERCHIN, H. Roger LIJNEN, Berthe Van HOEF, Frans De COCK, Désiré COLLEN

Journal:

Year:

1989

Language:

english

File:

PDF, 939 KB

english, 1989

71

Construction and characterization of a recombinant murine monoclonal antibody directed against human fibrin fragment-D dimer

Anne-Mieke VANDAMME, Frank BULENS, Hilde BERNAR, Luc NELLES, Roger H. LIJNEN, Désiré COLLEN

Journal:

Year:

1990

Language:

english

File:

PDF, 1.07 MB

english, 1990

72

Construction and characterization of a functional chimeric murine – human antibody directed against human fibrin fragment-D dimer

Frank BULENS, Anne-Mieke VANDAMME, Hilde BERNAR, Luc NELLES, Roger H. LIJNEN, Désiré COLLEN

Journal:

Year:

1991

Language:

english

File:

PDF, 872 KB

english, 1991

73

Effect of retinoic acid on the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in human endothelial cells

E. Anne THOMPSON, Luc NELLES, Désiré COLLEN

Journal:

Year:

1991

Language:

english

File:

PDF, 604 KB

english, 1991

74

Characterization of a recombinant chimeric plasminogen activator composed of a fibrin fragment-d-dimer-specific humanized monoclonal antibody and a truncated single-chain urokinase

Anne-Mieke VANDAMME, Maria DEWERCHIN, H. Roger LIJNEN, Hilde BERNAR, Frank BULENS, Luc NELLES, Désiré COLLEN

Journal:

Year:

1992

Language:

english

File:

PDF, 871 KB

english, 1992

75

Biochemical properties of recombinant single-chain urokinase-type plasminogen activator mutants with deletion of Asn2 through Phe157 and/or substitution of Cys279 with Ala

Henri R. LIJNEN, Xian-Kui LI, Luc NELLES, Mei-Hao HU, Désiré COLLEN

Journal:

Year:

1992

Language:

english

File:

PDF, 974 KB

english, 1992

76

Biochemical characterization of single-chain chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody and single-chain urokinase

Paul HOLVOET, Yves LAROCHE, Henri Roger LIJNEN, Berthe VAN HOEF, Els BROUWERS, Frans DE COCK, Marc LAUWEREYS, Yannick GANSEMANS, Désiré COLLEN

Journal:

Year:

1992

Language:

english

File:

PDF, 896 KB

english, 1992

77

Mechanisms of activation of mammalian plasma fibrinolytic systems with streptokinase and with recombinant staphylokinase

Desiré COLLEN, Berthe VAN HOEF, Bernhard SCHLOTT, Manfred HARTMANN, Karl-Heinz GÜHRS, H. Roger LIJNEN

Journal:

Year:

1993

Language:

english

File:

PDF, 913 KB

english, 1993

78

Interaction of staphylokinase with different molecular forms of plasminogen

H. Roger LIJNEN, Berthe VAN HOEF, Désiré COLLEN

Journal:

Year:

1993

Language:

english

File:

PDF, 916 KB

english, 1993

79

Characterization of the Binding of Urokinase-type Plasminogen Activator (u-PA) to Plasminogen, to Plasminogen-activator Inhibitor-1 and to the u-PA Receptor

H. Roger Lijnen, Frans De Cock, Désiré Collen

Journal:

Year:

1994

Language:

english

File:

PDF, 929 KB

english, 1994

80

Characterization of the Murine Plasma Fibrinolytic System

H. Roger Lijnen, Berthe Van Hoef, Veerle Beelen, Désiré Collen

Journal:

Year:

1994

Language:

english

File:

PDF, 1.16 MB

english, 1994

81

The thermostability of natural variants of bacterial plasminogen-activator staphylokinase

Ariane GASE, Eckhard BIRCH-HIRSCHFELD, Karl-Heinz GÜHRS, Manfred HARTMANN, Stefan VETTERMAN, Gregor DAMASCHUN, Hilde DAMASCHUN, Klaus GAST, Rolf MISSELWITZ, Dietrich ZIRWER, Désiré COLLEN, Bernhard SC

Journal:

Year:

1994

Language:

english

File:

PDF, 566 KB

english, 1994

82

Characterization of the Interaction Between Plasminogen and Staphylokinase

H. Roger Lijnen, Frans De Cock, Berthe Van Hoef, Bernhard Schlott, Désiré Collen

Journal:

Year:

1994

Language:

english

File:

PDF, 833 KB

english, 1994

83

Structural Domains of Streptokinase Involved in the Interaction with Plasminogen

Pedro Rodríguez, Pablo Fuentes, Mario Barro, Julio G. Alvarez, Emilio Muñoz, Désiré Collen, H. Roger Lijnen

Journal:

Year:

1995

Language:

english

File:

PDF, 1005 KB

english, 1995

84

Functional Properties of a Recombinant Chimeric Protein with Combined Thrombin Inhibitory and Plasminogen-Activating Potential

H. Roger Lijnen, Stephan Wnendt, Johannes Schneider, Elke Janocha, Berthe Van Hoef, Désiré Collen, Gerd J. Steffens

Journal:

Year:

1995

Language:

english

File:

PDF, 1.02 MB

english, 1995

85

Characterization of the murine plasminogen/urokinase-type plasminogen-activator system

H. Roger Lijnen, Berthe Van Hoef, Désiré Collen

Journal:

Year:

1996

Language:

english

File:

PDF, 1.13 MB

english, 1996

86

Enzymatic Properties of Phage-Displayed Fragments of Human Plasminogen

Ignace Lasters, Nathalie Van Herzeele, H. Roger Lijnen, Désiré Collen, Laurent Jespers

Journal:

Year:

1997

Language:

english

File:

PDF, 805 KB

english, 1997

87

Role of the Carboxy-Terminal Domain of Human Apolipoprotein AI in High-Density-Lipoprotein Metabolism : A Study Based on Deletion and Substitution Variants in Transgenic Mice

Paul Holvoet, Sophie Danloy, Desiré Collen

Journal:

Year:

1997

Language:

english

File:

PDF, 663 KB

english, 1997

88

Bone Marrow Stromal Cells as Targets for Gene Therapy of Hemophilia A

Chuah, Marinee K. L., Brems, Hilde, Vanslembrouck, Veerle, Collen, Desire, VandenDriessche, Thierry

Journal:

Human Gene Therapy

Year:

1998

Language:

english

File:

PDF, 8.71 MB

english, 1998

89

Targeted Deletion of the Cytosolic Domain of Tissue Factor in Mice Does Not Affect Development

Els Melis, Lieve Moons, Maria De Mol, Jean-Marc Herbert, Nigel Mackman, Désiré Collen, Peter Carmeliet, Mieke Dewerchin

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 226 KB

english, 2001

90

Epitope mapping by negative selection of randomized antigen libraries displayed on filamentous phage

Laurent Jespers, Stéphane Jenné, Ignace Lasters, Désiré Collen

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 339 KB

english, 1997

91

Guiding a docking mode by phage display: selection of correlated mutations at the staphylokinase-plasmin interface

Laurent Jespers, H.Roger Lijnen, Sophie Vanwetswinkel, Berthe Van Hoef, Katleen Brepoels, Désiré Collen, Marc De Maeyer

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 286 KB

english, 1999

92

Coronary thrombolysis in patients with acute myocardial infarction by intravenous infusion of synergic thrombolytic agents

Désiré Collen, David C Stump, Frans van de Werf

Journal:

American Heart Journal

Year:

1986

Language:

english

File:

PDF, 242 KB

english, 1986

93

Dose-dependent thrombolysis, pharmacokinetics and hemostatic effects of recombinant human tissue-type plasminogen activator for coronary thrombosis

Harry D. Garabedian, Herman K. Gold, Robert C. Leinbach, Tsunehiro Yasuda, Jennifer A. Johns, Désiré Collen

Journal:

The American Journal of Cardiology

Year:

1986

Language:

english

File:

PDF, 884 KB

english, 1986

94

The interaction in human plasma of antiplasmin, the fast-reacting plasmin inhibitor, with plasmin, thrombin, trypsin and chymotrypsin

Judith Edy, Désiré Collen

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1977

Language:

english

File:

PDF, 1.46 MB

english, 1977

95

Neoantigenic expression in enzyme·inhibitor complexes a means to demonstrate activation of enzyme systems

Desire Collen, Frans de Cock

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1978

Language:

english

File:

PDF, 736 KB

english, 1978

96

Molecular mechanisms of thrombolysis: Implications for therapy

Désiré Collen, Henri Roger Lijnen

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 1005 KB

english, 1990

97

Expression of aggrecan(ases) during murine preadipocyte differentiation and adipose tissue development

Gabor Voros, John D. Sandy, Désiré Collen, H. Roger Lijnen

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2006

Language:

english

File:

PDF, 732 KB

english, 2006

98

Effect of matrix metalloproteinase inhibition on adipose tissue development

Diego Demeulemeester, Désiré Collen, H. Roger Lijnen

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

99

Thrombophilia in mice expressing a tissue factor variant lacking its transmembrane and cytosolic domain

Els Melis, Lieve Moons, Jef Arnout, Marc F. Hoylaerts, Désiré Collen, Peter Carmeliet, Mieke Dewerchin

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 1.21 MB

english, 2005

100

Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke

Nobuo Nagai, Kiyotaka Okada, Naoyuki Kawao, Chikako Ishida, Shigeru Ueshima, Desire Collen, Osamu Matsuo

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 795 KB

english, 2008