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51

NMR structural characterization of the N-terminal active domain of the gyrase B subunit from Pseudomonas aeruginosa and its complex with an inhibitor

Li, Yan, Wong, Yun Xuan, Poh, Zhi Ying, Wong, Ying Lei, Lee, Michelle Yueqi, Ng, Hui Qi, Liu, Boping, Hung, Alvin W., Cherian, Joseph, Hill, Jeffrey, Keller, Thomas H., Kang, CongBao

Journal:

Year:

2015

Language:

english

File:

PDF, 2.93 MB

english, 2015

52

Selection of suitable detergents for obtaining an active dengue protease in its natural form from E. coli

Liew, Lynette Sin Yee, Lee, Michelle Yueqi, Wong, Ying Lei, Cheng, Jinting, Li, Qingxin, Kang, CongBao

Journal:

Protein Expression and Purification

Year:

2016

Language:

english

File:

PDF, 1.88 MB

english, 2016

53

Characterization of the Molecular Interactions between ParE/Gyrb and an Inhibitor and its Insight into Developing Antibacterial Agents

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

54

NMR Structural Characterization for Proteases of Dengue and West Nile Viruses and its Insight into Drug Discovery

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 45 KB

english, 2015

55

Solution NMR Study of the Transmembrane Domain of Single-Span Membrane Proteins: Opportunities and Strategies

Gayen, Shovanlal, Li, Qingxin, Kang, Congbao

Journal:

Current Protein & Peptide Science

Year:

2012

Language:

english

File:

PDF, 705 KB

english, 2012

56

Application of Fragment-Based Drug Discovery against DNA Gyrase B

Chen, Guo-Ying, Ng, Fui Mee, Tan, Yih Wan, Poulsen, Anders, Seetoh, Weiguang, Lin, Grace, Kang, CongBao, Then, Siew Wen, Ahmad, Nur Huda, Wong, Ying Lei, Ng, Hui Qi, Chia, C. S. Brian, Lau, Qiu Ying,

Journal:

Year:

2015

Language:

english

File:

PDF, 914 KB

english, 2015

57

Secondary Structure and Membrane Topology of the Full-Length Dengue Virus NS4B in Micelles

Li, Yan, Wong, Ying Lei, Lee, Michelle Yueqi, Li, Qingxin, Wang, Qing-Yin, Lescar, Julien, Shi, Pei-Yong, Kang, CongBao

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 2.10 MB

english, 2016

58

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

Phoo, Wint Wint, Li, Yan, Zhang, Zhenzhen, Lee, Michelle Yueqi, Loh, Ying Ru, Tan, Yaw Bia, Ng, Elizabeth Yihui, Lescar, Julien, Kang, CongBao, Luo, Dahai

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

59

Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport

Rajan, Sreekanth, Choi, Minjoo, Nguyen, Quoc Toan, Ye, Hong, Liu, Wei, Toh, Hui Ting, Kang, CongBao, Kamariah, Neelagandan, Li, Chi, Huang, Huiya, White, Carl, Baek, Kwanghee, Grüber, Gerhard, Yoon, H

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

60

Secondary Structure and Membrane Topology of the Full-Length Dengue Virus NS4B in Micelles

Li, Yan, Wong, Ying Lei, Lee, Michelle Yueqi, Li, Qingxin, Wang, Qing-Yin, Lescar, Julien, Shi, Pei-Yong, Kang, CongBao

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 3.58 MB

english, 2016

61

Structure of the transmembrane domain of human nicastrin-a component of γ-secretase

Li, Yan, Liew, Lynette Sin Yee, Li, Qingxin, Kang, CongBao

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

62

Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors

Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Wang, Weiling, Liu, Shuang, Chen, Ming Wei, Hung, Alvin W., Keller, Thomas H., Luo, Dahai, Kang, CongBao

Journal:

Year:

2017

Language:

english

File:

PDF, 3.56 MB

english, 2017

63

Structural characterization of the linked NS2B-NS3 protease of Zika virus

Li, Yan, Phoo, Wint Wint, Loh, Ying Ru, Zhang, Zhenzhen, Ng, Elizabeth Yihui, Wang, Weiling, Keller, Thomas H., Luo, Dahai, Kang, CongBao

Journal:

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

64

Functional role of the flexible N-terminal extension of FKBP38 in catalysis

Kang, CongBao, Ye, Hong, Chia, Joel, Choi, Bo-Hwa, Dhe-Paganon, Sirano, Simon, Bernd, Schütz, Ulrike, Sattler, Michael, Yoon, Ho Sup

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 1.97 MB

english, 2013

65

Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome

Li, Yan, Ng, Hui Qi, Li, Qingxin, Kang, CongBao

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.35 MB

english, 2016

66

Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles

Li, Qingxin, Lei Wong, Ying, Yueqi Lee, Michelle, Li, Yan, Kang, CongBao

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

67

Zika Virus Protease: An Antiviral Drug Target

Kang, CongBao, Keller, Thomas H., Luo, Dahai

Journal:

Trends in Microbiology

Year:

2017

Language:

english

File:

PDF, 3.33 MB

english, 2017

68

Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor

Li, Yan, Ng, Hui Qi, Ngo, Anna, Liu, Shuang, Tan, Yih Wan, Kwek, Perlyn Zekui, Hung, Alvin W., Joy, Joma, Hill, Jeffrey, Keller, Thomas H., Kang, CongBao

Journal:

Biomolecular NMR Assignments

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

69

Secondary structure and membrane topology of dengue virus NS4A protein in micelles

Li, Yan, Lee, Michelle Yueqi, Loh, Ying Ru, Kang, CongBao

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2017

Language:

english

File:

PDF, 1.75 MB

english, 2017

70

Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor

Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Li, Rong, Yang, Hai Yan, Jansson, Anna E., Hill, Jeffrey, Keller, Thomas H., Nacro, Kassoum, Luo, Dahai, Kang, CongBao

Journal:

Year:

2018

Language:

english

File:

PDF, 3.33 MB

english, 2018

71

Structural and ligand binding analysis of the YAP-binding domain of transcription factor TEAD4

Li, Yan, Liu, Shuang, Ng, Elizabeth Yihui, Li, Rong, Poulsen, Anders, Hill, Jeffrey, Pobatti, Ajaybabu V., Hung, Alvin W., Hong, Wanjin, Keller, Thomas H., Kang, CongBao

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 8.64 MB

english, 2018

72

Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH 2

Lau, Qiu Ying, Li, Jianguo, Sani, Marc-Antoine, Sinha, Sheetal, Li, Yan, Ng, Fui Mee, Kang, CongBao, Bhattacharjya, Surajit, Separovic, Frances, Verma, Chandra, Chia, Cheng San Brian

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2018

Language:

english

File:

PDF, 8.37 MB

english, 2018

73

The Natively Disordered Loop of Bcl-2 Undergoes Phosphorylation-Dependent Conformational Change and Interacts with Pin1

Kang, CongBao, Bharatham, Nagakumar, Chia, Joel, Mu, Yuguang, Baek, Kwanghee, Yoon, Ho Sup, Uversky, Vladimir N.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

74

Characterization of molecular interactions between Zika virus protease and peptides derived from the C-terminus of NS2B

Li, Yan, Loh, Ying Ru, Hung, Alvin W., Kang, CongBao

Journal:

Biochemical and Biophysical Research Communications

Year:

2018

Language:

english

File:

PDF, 1.70 MB

english, 2018

75

Structure of the C-terminal Region of the Frizzled Receptor 1 in Detergent Micelles

Gayen, Shovanlal, Li, Qingxin, Kim, Young, Kang, CongBao

Journal:

Year:

2013

Language:

english

File:

PDF, 1.52 MB

english, 2013

76

Identification of covalent active site inhibitors of dengue virus protease

Koh-Stenta, Xiaoying, Joy, Joma, Wang, Si Fang, Kwek, Perlyn, Wee, John, Wan, Kah Fei, Gayen, Shovanlal, Chen, Angela, Kang, CongBao, Lee, May Ann, Poulsen, Anders, Vasudevan, Subhash, Hill, Jeffrey,

Journal:

Drug Design Development and Therapy

Year:

2015

Language:

english

File:

PDF, 3.01 MB

english, 2015

77

Expression, purification of Zika virus membrane protein-NS2B in detergent micelles for NMR studies

Ng, Elizabeth Yihui, Loh, Ying Ru, Li, Yan, Li, Qingxin, Kang, CongBao

Journal:

Protein Expression and Purification

Year:

2019

Language:

english

File:

PDF, 6.13 MB

english, 2019

78

Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase

Li, Yan, Zhong, Wenhe, Koay, Ann Zhufang, Ng, Hui Qi, Koh-Stenta, Xiaoying, Nah, Qianhui, Lim, Siau Hoi, Larsson, Andreas, Lescar, Julien, Hill, Jeffrey, Dedon, Peter C., Kang, CongBao

Journal:

Biomolecular NMR Assignments

Year:

2018

Language:

english

File:

PDF, 2.33 MB

english, 2018

79

Secondary Structure and Topology of the Transmembrane Domain of Syndecan-2 in Detergent Micelles

Li, Qingxin, Ng, Hui Qi, Kang, CongBao

Journal:

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

80

Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease

Quek, Jun Ping, Liu, Shuang, Zhang, Zhenzhen, Li, Yan, Ng, Elizabeth Yihui, Loh, Ying Ru, Hung, Alvin W., Luo, Dahai, Kang, CongBao

Journal:

Antiviral Research

Year:

2020

Language:

english

File:

PDF, 4.13 MB

english, 2020

81

A Practical Perspective on the Roles of Solution NMR Spectroscopy in Drug Discovery

Li, Qingxin, Kang, CongBao

Journal:

Year:

2020

File:

PDF, 3.56 MB

2020

82

Mechanisms of Action for Small Molecules Revealed by Structural Biology in Drug Discovery

Li, Qingxin, Kang, CongBao

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 3.07 MB

2020

83

Progress in Developing Inhibitors of SARS-CoV-2 3C-Like Protease

Li, Qingxin, Kang, CongBao

Journal:

Year:

2020

File:

PDF, 1.70 MB

2020