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51

Comparison of blood toluene levels after inhalation and oral administration

Michael J. Sullivan, Rory B. Conolly

Journal:

Environmental Research

Year:

1988

Language:

english

File:

PDF, 350 KB

english, 1988

52

Physiologically based pharmacokinetic models applicable to organogenesis: extrapolation between species and potential use in prenatal toxicity risk assessments

Frank Welsch, Gregory M. Blumenthal, Rory B. Conolly

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 697 KB

english, 1995

53

The role of regenerative cell proliferation in chloroform-induced cancer

Byron E. Butterworth, Michael V. Templin, Susan J. Borghoff, Rory B. Conolly, Gregory L. Kedderis, Douglas C. Wolf

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 430 KB

english, 1995

54

Biologically based dose response model for hepatic toxicity: a mechanistically based replacement for traditional estimates of noncancer risk

Rory B. Conolly, Byron E. Butterworth

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 576 KB

english, 1995

55

Issues in the Design and Interpretation of Chronic Toxicity and Carcinogenicity Studies in Rodents: Approaches to Dose Selection

Rhomberg, Lorenz R., Baetcke, Karl, Blancato, Jerry, Bus, James, Cohen, Samuel, Conolly, Rory, Dixit, Rakesh, Doe, John, Ekelman, Karen, Fenner-Crisp, Penny, Harvey, Paul, Hattis, Dale, Jacobs, Abigai

Journal:

Critical Reviews in Toxicology

Year:

2007

Language:

english

File:

PDF, 2.41 MB

english, 2007

56

A framework for fit-for-purpose dose response assessment

Bette Meek, M.E., Bolger, Michael, Bus, James S., Christopher, John, Conolly, Rory B., Lewis, R. Jeffrey, Paolini, Gregory M., Schoeny, Rita, Haber, Lynne T., Rosenstein, Amy B., Dourson, Michael L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 363 KB

english, 2013

57

Pharmacokinetics, biochemical mechanism and mutation accumulation: a comprehensive model of chemical carcinogenesis

Conolly, Rory B., Reitz, Richard H., Clewell, Harvey J., Andersen, Melvin E.

Journal:

Toxicology Letters

Year:

1988

Language:

english

File:

PDF, 722 KB

english, 1988

58

All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

Zhang, Qiang, Kline, Douglas E., Bhattacharya, Sudin, Crawford, Robert B., Conolly, Rory B., Thomas, Russell S., Andersen, Melvin E., Kaminski, Norbert E.

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

59

In the near foreseeable future, much of toxicity testing can be replaced by computational approaches

Conolly, Rory B., Loizou, George

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 50 KB

english, 2013

60

Modeling Interindividual Variation in Physiological Factors Used in PBPK Models of Humans

Price, Paul S., Conolly, Rory B., Chaisson, Christine F., Gross, Elizabeth A., Young, John S., Mathis, Eric T., Tedder, Douglas R.

Journal:

Critical Reviews in Toxicology

Year:

2003

Language:

english

File:

PDF, 273 KB

english, 2003

61

Comparative ototoxicity of gentamicin in the guinea pig and two strains of rats

Sullivan, Michael J., Rarey, Kyle E., Conolly, Rory B.

Journal:

Hearing Research

Year:

1987

Language:

english

File:

PDF, 771 KB

english, 1987

62

Acute Hepatotoxicity of Ethylene and Halogenated Ethylenes after PCB Pretreatment

Rory B. Conolly and Rudolph J. Jaeger

Journal:

Environmental Health Perspectives

Year:

1977

Language:

english

File:

PDF, 275 KB

english, 1977

63

Biochemical Toxicology of Unsaturated Halogenated Monomers

Rudolph J. Jaeger, Rory B. Conolly, E. S. Reynolds and Sheldon D. Murphy

Journal:

Environmental Health Perspectives

Year:

1975

Language:

english

File:

PDF, 2.08 MB

english, 1975

64

Supplement 4 || Quantitative Mechanistically Based Dose-Response Modeling with Endocrine-Active Compounds

Melvin E. Andersen, Rory B. Conolly, Elaine M. Faustman, Robert J. Kavlock, Christopher J. Portier, Daniel M. Sheehan, Patrick J. Wier and Lauren Ziese

Journal:

Environmental Health Perspectives

Year:

1999

Language:

english

File:

PDF, 2.10 MB

english, 1999

65

Supplement 6: Health Effects of Gasoline || An Approach to Mechanism-based Cancer Risk Assessment for Formaldehyde

Rory B. Conolly and Melvin E. Andersen

Journal:

Environmental Health Perspectives

Year:

1993

Language:

english

File:

PDF, 1.65 MB

english, 1993

66

Supplement 5 || Simulation Modeling of the Tissue Disposition of Formaldehyde to Predict Nasal DNA-Protein Cross-Links in Fischer 344 Rats, Rhesus Monkeys, and Humans

Rory B. Conolly, Patrick D. Lilly and Julia S. Kimbell

Journal:

Environmental Health Perspectives

Year:

2000

Language:

english

File:

PDF, 1.43 MB

english, 2000

67

Computational Model of Steroidogenesis in Human H295R Cells to Predict Biochemical Response to Endocrine-Active Chemicals: Model Development for Metyrapone

Michael S. Breen, Miyuki Breen, Natsuko Terasaki, Makoto Yamazaki and Rory B. Conolly

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 2.18 MB

english, 2010

68

Arsenic-Induced Carcinogenesis—Oxidative Stress as a Possible Mode of Action and Future Research Needs for More Biologically Based Risk Assessment

Kitchin, Kirk T., Conolly, Rory

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 1.21 MB

english, 2010

69

Bayesian Calibration of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model of Carbaryl Cholinesterase Inhibition

Nong, Andy, Tan, Yu-Mei, Krolski, Michael E., Wang, Jiansuo, Lunchick, Curt, Conolly, Rory B., Clewell, Harvey J.

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 435 KB

english, 2008

70

Biologically Motivated Approaches to Extrapolation from High to Low Doses and the Advent of Systems Biology: The Road to Toxicological Safety Assessment

Conolly, Rory B., Thomas, Russell S.

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2007

Language:

english

File:

PDF, 69 KB

english, 2007

71

Dose-Response Hearing Loss for White Noise in the Sprague-Dawley Rat

SULLIVAN, MICHAEL J., CONOLLY, RORY B.

Journal:

Toxicological Sciences

Year:

1988

Language:

english

File:

PDF, 372 KB

english, 1988

72

Use of a Physiologically Based Pharmacokinetic Model and Computer Simulation for Retrospective Assessment of Exposure to Volatile Toxicants

Vinegar, Allen, Winsett, Darrell W., Andersen, Melvin E., Conolly, Rory B.

Journal:

Inhalation Toxicology

Year:

1990

Language:

english

File:

PDF, 582 KB

english, 1990

73

The fractions of respiratory tract cells at risk in formaldehyde carcinogenesis

Miller, Frederick J., Kimbell, Julia S., Preston, R. Julian, Overton, John H., Gross, Elizabeth A., Conolly, Rory B.

Journal:

Inhalation Toxicology

Year:

2011

Language:

english

File:

PDF, 838 KB

english, 2011

74

Use of a Physiologically Based Pharmacokinetic Model to Identify Exposures Consistent With Human Biomonitoring Data for Chloroform

Tan, Yu-Mei, Liao, Kai H., Conolly, Rory B., Blount, Benjamin C., Mason, Ann M., Clewell, Harvey J.

Journal:

Journal of Toxicology and Environmental Health

Year:

2006

Language:

english

File:

PDF, 264 KB

english, 2006

75

A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens

Felter, Susan P., Conolly, Rory B., Bercu, Joel P., Bolger, P. Michael, Boobis, Alan R., Bos, Peter M. J., Carthew, Philip, Doerrer, Nancy G., Goodman, Jay I., Harrouk, Wafa A., Kirkland, David J., La

Journal:

Critical Reviews in Toxicology

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

76

DNA—Protein Cross-Links (DPX) and Cell Proliferation in B6C3F 1 Mice but Not Syrian Golden Hamsters Exposed to Dichloromethane: Pharmacokinetics and Risk Assessment with DPX as Dosimeter

CASANOVA, MERCEDES, CONOLLY, RORY B., HECK, HENRY D'A.

Journal:

Toxicological Sciences

Year:

1996

Language:

english

File:

PDF, 4.00 MB

english, 1996

77

Polychlorotrifluoroethylene (PCTFE) Oligomer Pharmacokinetics in Fischer 344 Rats: Development of a Physiologically Based Model

VINEGAR, ALLEN, SECKEL, CONNIE S., POLLARD, DANIEL L., KINKEAD, EDWIN R., CONOLLY, RORY B., ANDERSEN, MELVIN E.

Journal:

Toxicological Sciences

Year:

1992

Language:

english

File:

PDF, 875 KB

english, 1992

78

Computational Systems Biology and Dose-Response Modeling in Relation to New Directions in Toxicity Testing

Zhang, Qiang, Bhattacharya, Sudin, Andersen, Melvin E., Conolly, Rory B.

Journal:

Journal of Toxicology and Environmental Health Part B

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

79

Assessing The Health Effects and Risks Associated with Children's Inhalation Exposures—Asthma and Allergy

Selgrade, MaryJane K., Plopper, Charles G., Gilmour, M. Ian, Conolly, Rory B., Foos, Brenda S. P.

Journal:

Journal of Toxicology and Environmental Health

Year:

2007

Language:

english

File:

PDF, 2.87 MB

english, 2007

80

Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses

Zhang, Qiang, Bhattacharya, Sudin, Conolly, Rory B., Clewell, Harvey J., Kaminski, Norbert E., Andersen, Melvin E.

Journal:

Environmental Health Perspectives

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

81

Computational Model of Steroidogenesis in Human H295R Cells to Predict Biochemical Response to Endocrine-Active Chemicals: Model Development for Metyrapone

Breen, Michael S., Breen, Miyuki, Terasaki, Natsuko, Yamazaki, Makoto, Conolly, Rory B.

Journal:

Environmental Health Perspectives

Year:

2009

Language:

english

File:

PDF, 2.19 MB

english, 2009

82

Comparative in vivo genotoxicity and acute hepatotoxicity of three 1,2-dihaloethanes

Storer, Richard D., Conolly, Rory B.

Journal:

Year:

1983

Language:

english

File:

PDF, 418 KB

english, 1983

83

A 90-Day Chloroform Inhalation Study in Female and Male B6C3F 1 Mice: Implications for Cancer Risk Assessment

LARSON, JEFFREY L., TEMPLIN, MICHAEL V., WOLF, DOUGLAS C., JAMISON, KEITH C., LEINNINGER, JOEL R., MÈRY, STEPHANE, MORGAN, KEVIN T., WONG, BRAIN A., CONOLLY, RORY B., BUTTERWORTH, BYRON E.

Journal:

Toxicological Sciences

Year:

1996

Language:

english

File:

PDF, 5.18 MB

english, 1996

84

Relationship between Hepatocyte Necrosis, Proliferation, and Initiation Induced by Diethylnitrosamine in the Male F344 Rat

KATO, MICHIYUKI, POPP, JAMES A., CONOLLY, RORY B., CATTLEY, RUSSELL C.

Journal:

Toxicological Sciences

Year:

1993

Language:

english

File:

PDF, 670 KB

english, 1993

85

Improvements in Quantitative Noncancer Risk Assessment

BECK, BARBARA D., CONOLLY, RORY B., DOURSON, MICHAEL L., GUTH, DANIEL, HATTIS, DALE, KIMMEL, CAROLE, LEWIS, STEVEN C.

Journal:

Toxicological Sciences

Year:

1993

Language:

english

File:

PDF, 2.65 MB

english, 1993

86

Mixed‐function oxidase system induction and propylene hepatotoxicity

Osimitz, Thomas G., Conolly, Rory B.

Journal:

Journal of Toxicology and Environmental Health

Year:

1985

Language:

english

File:

PDF, 802 KB

english, 1985

87

Drinking Water and Health: Balancing Risks || Determining Health Risks Associated With Disinfectants and Disinfection By-products: Research Needs

William H. Glaze, Julian B. Andelman, Richard J. Bull, Rory B. Conolly, Charles D. Hertz, Ronald D. Hood and Rex A. Pegram

Journal:

American Water Works Association

Year:

1993

Language:

english

File:

PDF, 945 KB

english, 1993

88

Pretreatment of primary rat cutaneous epidermal keratinocyte culture with a low concentration of MNNG: Effect on DNA cross‐linking measured in situ after challenge with bis‐2‐chloroethyl sulfide

Sorscher, David H., Conolly, Rory B.

Journal:

Journal of Toxicology and Environmental Health

Year:

1989

Language:

english

File:

PDF, 1019 KB

english, 1989

89

Computational Modeling of Signaling Pathways Mediating Cell Cycle Checkpoint Control and Apoptotic Responses to Ionizing Radiation-Induced DNA Damage

Zhao, Yuchao, Lou, In Chio, Conolly, Rory B.

Journal:

Year:

2012

Language:

english

File:

PDF, 5.03 MB

english, 2012

90

Computational model of the fathead minnow hypothalamic–pituitary–gonadal axis: Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals

Breen, Miyuki, Villeneuve, Daniel L., Ankley, Gerald T., Bencic, David, Breen, Michael S., Watanabe, Karen H., Lloyd, Alun L., Conolly, Rory B.

Journal:

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.44 MB

english, 2016

91

Short-Term Inhalation Toxicity of Halogenated Hydrocarbons

Jaeger, Rudolph J., Conolly, Rory B., Murphy, Sheldon D.

Journal:

Archives of Environmental Health An International Journal

Year:

1975

Language:

english

File:

PDF, 724 KB

english, 1975

92

Drinking Water and Health: Balancing Risks || Incorporating Biologically Based Models Into Assessments of Risk From Chemical Contaminants

Richard J. Bull, Rory B. Conolly, David M. De Marini, Robert C. MacPhail, Edward V. Ohanian and James A. Swenberg

Journal:

American Water Works Association

Year:

1993

Language:

english

File:

PDF, 1.42 MB

english, 1993

93

Computational modeling of plasma vitellogenin alterations in response to aromatase inhibition in fathead minnows

Cheng, Wan-Yun, Zhang, Qiang, Schroeder, Anthony, Villeneuve, Daniel L., Ankley, Gerald T., Conolly, Rory

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 717 KB

english, 2016

94

Supplement 11: Dosimetry for Risk Assessment || Physiologically Based Pharmacokinetic Model for the Inhibition of Acetylcholinesterase by Organophosphate Esters

Jeffery M. Gearhart, Gary W. Jepson, Harvey J. Clewell, Melvin E. Andersen and Rory B. Conolly

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 2.25 MB

english, 1994

95

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology

Conolly, Rory B., Ankley, Gerald T., Cheng, WanYun, Mayo, Michael L., Miller, David H., Perkins, Edward J., Villeneuve, Daniel L., Watanabe, Karen H.

Journal:

Environmental Science & Technology

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

96

A case study application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) frameworks to facilitate the integration of human health and ecological endpoints for Cumulative Risk Assessment (CRA)

Hines, David E., Edwards, Stephen, Conolly, Rory B., Jarabek, Annie M

Journal:

Environmental Science & Technology

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

97

An updated analysis of respiratory tract cells at risk for formaldehyde carcinogenesis

Miller, Frederick J., Conolly, Rory B., Kimbell, Julia S.

Journal:

Inhalation Toxicology

Year:

2018

Language:

english

File:

PDF, 1.30 MB

english, 2018

98

Changes in Metabolites Present in Lung Lining Fluid Following Exposure of Humans to Ozone

Cheng, WanYun, Duncan, Kelly E, Ghio, Andrew J, Ward-Caviness, Cavin, Karoly, Edward D, Diaz-Sanchez, David, Conolly, Rory B, Devlin, Robert B

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

99

Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: an example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxin

Andersen, Melvin E, Conolly, Rory B

Journal:

Human & Experimental Toxicology

Year:

1998

Language:

english

File:

PDF, 297 KB

english, 1998

100

High-Throughput Video Processing of Heart Rate Responses in Multiple Wild-type Embryonic Zebrafish per Imaging Field

Martin, W. Kyle, Tennant, Alan H., Conolly, Rory B., Prince, Katya, Stevens, Joey S, DeMarini, David M., Martin, Brandi L., Thompson, Leslie C., Gilmour, M. Ian, Cascio, Wayne E., Hays, Michael D., Ha

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.89 MB

english, 2019