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51

Activity-Based Probes for Monitoring Postproline Protease Activity

Eduard Sabidó, Teresa Tarragó, Sherry Niessen, Benjamin F. Cravatt, Ernest Giralt

Journal:

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

52

ChemInform Abstract: An Endogenous Sleep-Inducing Compound is a Novel Competitive Inhibitor of Fatty Acid Amide Hydrolase.

M. P. PATRICELLI, J. E. PATTERSON, D. L. BOGER, B. F. CRAVATT

Journal:

Year:

1998

File:

PDF, 29 KB

1998

53

(-)-FR182877 Is a Potent and Selective Inhibitor of Carboxylesterase-1.

Gregory C. Adam, Christopher D. Vanderwal, Erik J. Sorensen, Benjamin F. Cravatt

Journal:

Year:

2004

File:

PDF, 61 KB

2004

54

Discovery of an Exceptionally Potent and Selective Class of Fatty Acid Amide Hydrolase Inhibitors Enlisting Proteome-Wide Selectivity Screening: Concurrent Optimization of Enzyme Inhibitor Potency and Selectivity.

Donmienne Leung, Wu Du, Christophe Hardouin, Heng Cheng, Inkyu Hwang, Benjamin F. Cravatt, Dale L. Boger

Journal:

Year:

2005

File:

PDF, 14 KB

2005

55

Protein-Reactive Natural Products

Carmen Drahl, Benjamin F. Cravatt, Erik J. Sorensen

Journal:

Year:

2005

File:

PDF, 8 KB

2005

56

Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as neural signaling molecules

Michaela Egertová, Gabriel M. Simon, Benjamin F. Cravatt, Maurice R. Elphick

Journal:

The Journal of Comparative Neurology

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

57

Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei

Juan Suárez, Francisco Javier Bermúdez-Silva, Ken Mackie, Catherine Ledent, Andreas Zimmer, Benjamin F. Cravatt, Fernando Rodríguez de Fonseca

Journal:

The Journal of Comparative Neurology

Year:

2008

Language:

english

File:

PDF, 3.00 MB

english, 2008

58

Architecture of cannabinoid signaling in mouse retina

Sherry Shu-Jung Hu, Andy Arnold, Jacqueline M. Hutchens, Josh Radicke, Benjamin F. Cravatt, Jim Wager-Miller, Ken Mackie, Alex Straiker

Journal:

The Journal of Comparative Neurology

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

59

Hyperglycemia induces apoptosis via CB1 activation through the decrease of FAAH 1 in retianl pigment epithelial cells

Seul Ki Lim, Min Jung Park, Jae Cheong Lim, Jong Choon Kim, Ho Jae Han, Gye-Yeop Kim, Benjamin F. Cravatt, Chang Hoon Woo, Seung Jin Ma, Kyung Cheol Yoon, Soo Hyun Park

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

60

The endogenous cannabinoid system and its role in nociceptive behavior

Benjamin F. Cravatt, Aron H. Lichtman

Journal:

Developmental Neurobiology

Year:

2004

Language:

english

File:

PDF, 125 KB

english, 2004

61

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling

Heather S. Hoover, Jacqueline L. Blankman, Sherry Niessen, Benjamin F. Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 807 KB

english, 2008

62

Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity

Donmienne Leung, Wu Du, Christophe Hardouin, Heng Cheng, Inkyu Hwang, Benjamin F. Cravatt, Dale L. Boger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

63

Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase

Ian M. Slaymaker, Michael Bracey, Mauro Mileni, Joie Garfunkle, Benjamin F. Cravatt, Dale L. Boger, Raymond C. Stevens

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

64

Exploration of a fundamental substituent effect of α-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase

Jessica K. DeMartino, Joie Garfunkle, Dustin G. Hochstatter, Benjamin F. Cravatt, Dale L. Boger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

65

Tetrahedron Young Investigator Award 2008

Benjamin F. Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 124 KB

english, 2008

66

Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)

Daniel A. Bachovchin, Monique R. Wolfe, Kim Masuda, Steven J. Brown, Timothy P. Spicer, Virneliz Fernandez-Vega, Peter Chase, Peter S. Hodder, Hugh Rosen, Benjamin F. Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 561 KB

english, 2010

67

The development and application of methods for activity-based protein profiling

Nadim Jessani, Benjamin F Cravatt

Journal:

Current Opinion in Chemical Biology

Year:

2004

Language:

english

File:

PDF, 171 KB

english, 2004

68

Global strategies to integrate the proteome and metabolome

Alan Saghatelian, Benjamin F Cravatt

Journal:

Current Opinion in Chemical Biology

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

69

Proteomics and genomics: A chemo-centric view of proteomics and genomics

Benjamin F Cravatt, Thomas Kodadek

Journal:

Current Opinion in Chemical Biology

Year:

2005

Language:

english

File:

PDF, 65 KB

english, 2005

70

Genomics and proteomics: From genes to function: advances in applications of chemical and systems biology

Matthew Bogyo, Benjamin F Cravatt

Journal:

Current Opinion in Chemical Biology

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

71

Profiling Enzyme Activities In Vivo Using Click Chemistry Methods

Anna E Speers, Benjamin F Cravatt

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 492 KB

english, 2004

72

Discovering Disease-Associated Enzymes by Proteome Reactivity Profiling

Katherine T. Barglow, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 650 KB

english, 2004

73

Live Chemical Reports from the Cell Surface

Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 44 KB

english, 2005

74

Mechanism of Carbamate Inactivation of FAAH: Implications for the Design of Covalent Inhibitors and In Vivo Functional Probes for Enzymes

Jessica P. Alexander, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 377 KB

english, 2005

75

An Enzyme that Regulates Ether Lipid Signaling Pathways in Cancer Annotated by Multidimensional Profiling

Kyle P. Chiang, Sherry Niessen, Alan Saghatelian, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 433 KB

english, 2006

76

Chemical Proteomic Probes for Profiling Cytochrome P450 Activities and Drug Interactions In Vivo

Aaron T. Wright, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 530 KB

english, 2007

77

A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2-Arachidonoylglycerol

Jacqueline L. Blankman, Gabriel M. Simon, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 629 KB

english, 2007

78

Characterization of Monoacylglycerol Lipase Inhibition Reveals Differences in Central and Peripheral Endocannabinoid Metabolism

Jonathan Z. Long, Daniel K. Nomura, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

79

The Glycerophospho Metabolome and Its Influence on Amino Acid Homeostasis Revealed by Brain Metabolomics of GDE1(−/−) Mice

Florian Kopp, Toru Komatsu, Daniel K. Nomura, Sunia A. Trauger, Jason R. Thomas, Gary Siuzdak, Gabriel M. Simon, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 758 KB

english, 2010

80

A Potent and Selective Inhibitor of KIAA1363/AADACL1 that Impairs Prostate Cancer Pathogenesis

Jae Won Chang, Daniel K. Nomura, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 897 KB

english, 2011

81

Monoacylglycerol Lipase Exerts Dual Control over Endocannabinoid and Fatty Acid Pathways to Support Prostate Cancer

Daniel K. Nomura, Donald P. Lombardi, Jae Won Chang, Sherry Niessen, Anna M. Ward, Jonathan Z. Long, Heather H. Hoover, Benjamin F. Cravatt

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 937 KB

english, 2011

82

The enzymatic inactivation of the fatty acid amide class of signaling lipids

Benjamin F. Cravatt, Aron H. Lichtman

Journal:

Chemistry and Physics of Lipids

Year:

2002

Language:

english

File:

PDF, 324 KB

english, 2002

83

Fatty acid amide hydrolase substrate specificity

Dale L Boger, Robert A Fecik, Jean E Patterson, Hiroshi Miyauchi, Matthew P Patricelli, Benjamin F Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

84

An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase

Matthew P Patricelli, Jean E Patterson, Dale L Boger, Benjamin F Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 446 KB

english, 1998

85

Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: A probe of structural and conformational features contributing to inhibition

Dale L. Boger, Haruhiko Sato, Aaron E. Lerner, Bryce J. Austin, Jean E. Patterson, Matthew P. Patricelli, Benjamin F. Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 364 KB

english, 1999

86

Profiling the specific reactivity of the proteome with non-directed activity-based probes

Gregory C. Adam, Benjamin F. Cravatt, Erik J. Sorensen*

Journal:

Chemistry & Biology

Year:

2001

Language:

english

File:

PDF, 555 KB

english, 2001

87

Chemical strategies for the global analysis of protein function

Benjamin F Cravatt, Erik J Sorensen

Journal:

Current Opinion in Chemical Biology

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

88

Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system

Benjamin F Cravatt, Aron H Lichtman

Journal:

Current Opinion in Chemical Biology

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

89

The Endogenous Lipid Oleamide Activates Serotonin 5-HT7 Neurons in Mouse Thalamus and Hypothalamus

Elizabeth A. Thomas, Benjamin F. Cravatt, J. Gregor Sutcliffe

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 791 KB

english, 1999

90

The endocannabinoid anandamide is a precursor for the signaling lipidN-arachidonoyl glycine by two distinct pathways

Heather B Bradshaw, Neta Rimmerman, Sherry Shu-Jung Hu, Valery M Benton, Jordyn M Stuart, Kim Masuda, Benjamin F Cravatt, David K O'Dell, J Michael Walker

Journal:

BMC Biochemistry

Year:

2009

Language:

english

File:

PDF, 470 KB

english, 2009

91

Click Chemistry-Led Advances in High Content Functional Proteomics

Cleo M. Salisbury, Benjamin F. Cravatt

Journal:

Molecular Informatics

Year:

2007

Language:

english

File:

PDF, 485 KB

english, 2007

92

Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality

Pattipati S. Naidu, Stephen A. Varvel, Kyunghye Ahn, Benjamin F. Cravatt, Billy R. Martin, Aron H. Lichtman

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 289 KB

english, 2007

93

Observed freshening and warming of the western Pacific Warm Pool

Sophie Cravatte, Thierry Delcroix, Dongxiao Zhang, Michael McPhaden, Julie Leloup

Journal:

Climate Dynamics

Year:

2009

Language:

english

File:

PDF, 4.69 MB

english, 2009

94

Progress in addressing disparities through comprehensive cancer control

Armin D. Weinberg, Pamela M. Jackson, Christine A. DeCourtney, Kym Cravatt, Joanne Ogo, Marta M. Sanchez, Guillermo Tortolero-Luna, Rochelle L. Rollins

Journal:

Cancer Causes & Control

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

95

Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala

A. I. Gulyas, B. F. Cravatt, M. H. Bracey, T. P. Dinh, D. Piomelli, F. Boscia, T. F. Freund

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 1.76 MB

english, 2004

96

Book Review

Richard L. Cravatts

Journal:

Business Ethics: A European Review

Year:

2004

Language:

english

File:

PDF, 72 KB

english, 2004

97

COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation

A Straiker, J Wager-Miller, SS Hu, JL Blankman, BF Cravatt, K Mackie

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 2.24 MB

english, 2011

98

Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice

M Bashashati, MA Storr, SP Nikas, JT Wood, G Godlewski, J Liu, W Ho, CM Keenan, H Zhang, SO Alapafuja, BF Cravatt, B Lutz, K Mackie, G Kunos, KD Patel, A Makriyannis, JS Davison, KA Sharkey

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.46 MB

english, 2012

99

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Cravatt, Benjamin F., Giang, Dan K., Mayfield, Stephen P., Boger, Dale L., Lerner, Richard A., Gilula, Norton B.

Journal:

Year:

1996

File:

PDF, 1.23 MB

1996

100

10.1038/84273

Bain, Gretchen, Cravatt, Celia B., Loomans, Cindy, Alberola-Ila, Jose, Hedrick, Stephen M., Murre, Cornelis

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 445 KB

english, 2001

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