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51

Genetics of Increased HDL Cholesterol Levels: Insights Into the Relationship Between HDL Metabolism and Atherosclerosis

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2003

Language:

english

File:

PDF, 66 KB

english, 2003

52

Macrophage Reverse Cholesterol Transport: Key to the Regression of Atherosclerosis?

Journal:

Year:

2006

Language:

english

File:

PDF, 452 KB

english, 2006

53

ABCA1 and Inflammation: Figure.

Bi, Xin, Vitali, Cecilia, Cuchel, Marina

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2015

Language:

english

File:

PDF, 993 KB

english, 2015

54

Coronary artery disease-protective A43T variant in APOC3 alters circulating ApoC-III levels in vivo

Khetarpal, S., Varshini, A., Larach, D., Tabita-Martinez, J., McParland, J., McCoy, M., Rodrigues, A., Kiss, D., Zanoni, P., Mucksavage, M., Millar, J., Cuchel, M., Lund-Katz, S., Phillips, M., Kathir

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 52 KB

english, 2015

55

Cholesterol efflux capacity inversely correlates with HDL cholesterol fractional catabolic rate

Hancock-Cerutti, W., Valentini, S., Liu, J., Billheimer, J.T., Millar, J.S., Rader, D.J., Cuchel, M.

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 67 KB

english, 2015

56

Clinical and biochemical characteristics are varied in subjects with ABCA1 mutations

Cuchel, M., McParland, J.T., Wang, J., Hegele, R.A., Rader, D.J.

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 51 KB

english, 2015

57

In hyperalphalipoproteinemic subjects, the presence of coronary artery disease is associated with marked changes in the HDL phosphosphingolipidome

Hancock-Cerutti, W., Lhomme, M., Dauteuille, C., Lecocq, S., Chapman, J., Rader, D., Kontush, A., Cuchel, M.

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 56 KB

english, 2014

58

Microsomal triglyceride transfer protein transfers and determines plasma concentrations of ceramide and sphingomyelin, but not glycosylceramide

Iqbal, Jahangir, Walsh, Meghan T., Hammad, Samar M., Cuchel, Marina, Tarugi, Patrizia, Hegele, Robert A., Davidson, Nicholas O., Rader, Daniel J., Klein, Richard L., Hussain, M. Mahmood

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.94 MB

english, 2015

59

ApoA-I-Directed Therapies for the Management of Atherosclerosis

J. S. Millar, M. Cuchel

Journal:

Current Atherosclerosis Reports

Year:

2015

Language:

english

File:

PDF, 300 KB

english, 2015

60

Pathways by Which Reconstituted High-Density Lipoprotein Mobilizes Free Cholesterol From Whole Body and From Macrophages

Cuchel, M., Lund-Katz, S., de la Llera-Moya, M., Millar, J. S., Chang, D., Fuki, I., Rothblat, G. H., Phillips, M. C., Rader, D. J.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2010

Language:

english

File:

PDF, 783 KB

english, 2010

61

Infusion of Reconstituted High‐Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial

Tricoci, Pierluigi, D'Andrea, Denise M., Gurbel, Paul A., Yao, Zhenling, Cuchel, Marina, Winston, Brion, Schott, Robert, Weiss, Robert, Blazing, Michael A., Cannon, Louis, Bailey, Alison, Angiolillo,

Journal:

Journal of the American Heart Association

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

62

A deleterious mutation in scarb1 significantly alters HDL level, composition, and biological function in humans

Hancock-Cerutti, W., Zanoni, P., Lhomme, M., Lecocq, S., Dauteuille, C., Larach, D., Chapman, J., Cuchel, M., Rader, D., Kontush, A.

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 72 KB

english, 2014

63

Recent Developments in Gene Therapy for Homozygous Familial Hypercholesterolemia

Ajufo, Ezim, Cuchel, Marina

Journal:

Current Atherosclerosis Reports

Year:

2016

Language:

english

File:

PDF, 957 KB

english, 2016

64

Mutations in abca1 are associated with enhanced beta-cell secretory capacity in humans

Rickels, M., Goeser, E., Fuller, C., Lord, C., Bowler, A., Doliba, N., Hegele, R., Cuchel, M.

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 365 KB

english, 2014

65

A loss-of-function mutation in scarb1 severely impairs sr-bi processing and activity in humans

Zanoni, P., Larach, D.B., Khetarpal, S.A., Hancock-Cerutti, W.F., Peloso, G.M., Rodrigues, A., Tohyama, J., Billheimer, J.T., Kathiresan, S., Cuchel, M., Rader, D.J.

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 51 KB

english, 2014

66

Improving the yield of genetic testing in familial hypercholesterolaemia

Ajufo, Ezim, Cuchel, Marina

Journal:

European Heart Journal

Year:

2016

Language:

english

File:

PDF, 179 KB

english, 2016

67

Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component

Herzog, Eva, Pragst, Ingo, Waelchli, Marcel, Gille, Andreas, Schenk, Sabrina, Mueller-Cohrs, Jochen, Diditchenko, Svetlana, Zanoni, Paolo, Cuchel, Marina, Seubert, Andreas, Rader, Daniel J., Wright, S

Journal:

Journal of Applied Toxicology

Year:

2016

Language:

english

File:

PDF, 411 KB

english, 2016

68

Reduced β-Cell Secretory Capacity in Pancreatic Insufficient, But Not Pancreatic Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance

Sheikh, Saba, Gudipaty, Lalitha, De Leon, Diva D., Hadjiliadis, Denis, Kubrak, Christina, Rosenfeld, Nora K., Nyirjesy, Sarah, Pelekis, Amy, Malik, Saloni, Stefanovski, Darko, Cuchel, Marina, Rubenste

Journal:

Year:

2016

Language:

english

File:

PDF, 781 KB

english, 2016

69

Encyclopedia of Life Sciences || Familial Hypercholesterolemia: Gene Therapy

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

70

The plasma proteome of tangier disease patients reveals perturbations of diabetic and inflammatory pathways

McParland, J., Pashos, E., Rader, D., Cuchel, M.

Journal:

Atherosclerosis

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

71

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans

Cuchel, Marina, Raper, Anna C., Conlon, Donna M., Pryma, Daniel A., Freifelder, Richard H., Poria, Rahul, Cromley, Debra, Li, Xiaoyu, Dunbar, Richard L., French, Benjamin, Qu, Liming, Farver, William,

Journal:

The Journal of Lipid Research

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

72

ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion

Bi, Xin, Pashos, Evanthia E., Cuchel, Marina, Lyssenko, Nicholas N., Hernandez, Mayda, Picataggi, Antonino, McParland, James, Yang, Wenli, Liu, Ying, Yan, Ruilan, Yu, Christopher, DerOhannessian, Step

Journal:

Year:

2017

Language:

english

File:

PDF, 751 KB

english, 2017

73

An Electronic Health Records Query for Severe Hypercholesterolemia Identifies Individuals With Undiagnosed Clinical and Molecular FH at a Tertiary Academic Centre

Ajufo, Ezim, Ueda, Masako, Sikora, Tracey, deGoma, Emil, Dilzell, Kristen, Raper, Anna, DerOhannessian, Stephanie, Hossain, Erik, Cuchel, Marina, Rader, Daniel

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 66 KB

english, 2017

74

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress

Liu, Ying, Conlon, Donna M., Bi, Xin, Slovik, Katherine J., Shi, Jianting, Edelstein, Hailey I., Millar, John S., Javaheri, Ali, Cuchel, Marina, Pashos, Evanthia E., Iqbal, Jahangir, Hussain, M. Mahmo

Journal:

Year:

2017

Language:

english

File:

PDF, 3.13 MB

english, 2017

75

Safety and Efficacy of Evinacumab, A Monoclonal Antibody to ANGPTL3, In Homozygous Familial Hypercholesterolemia

Gaudet, Daniel, Gipe, Daniel, Hovingh, Kees, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman, Chyu, Kuang-Yuh, Pordy, Robert, Sasiela, William, Chan, Kuo-Chen, Khoury, Etienne

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 217 KB

english, 2017

76

Paradoxical coronary artery disease in humans with hyperalphalipoproteinemia is associated with distinct differences in the HDL phosphosphingolipidome

Hancock-Cerutti, William, Lhomme, Marie, Dauteuille, Carolane, Lecocq, Sora, Chapman, M. John, Rader, Daniel, Kontush, Anatol, Cuchel, Marina

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 1.46 MB

english, 2017

77

The Majority of Outpatients With Severe Hypercholesterolemia at an Academic Tertiary Centre Have Not Been Screened for FH

Ajufo, Ezim, Ueda, Masako, Hossain, Erik, Sikora, Tracey, Damrauer, Scott, deGoma, Emil, Dilzell, Kristen, DerOhannessian, Stephanie, Cuchel, Marina, Rader, Daniel

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 119 KB

english, 2017

78

Challenges in Interpreting Genetic Reports in Familial Hypercholesterolemia: Variants of Uncertain Significance

Ueda, Masako, Ajufo, Ezim, Dilzell, Kristen, Sikora, Tracey, Raper, Anna, DerOhannessian, Stephanie, Cuchel, Marina, deGoma, Emil, Rader, Daniel

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 212 KB

english, 2017

79

ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia

Gaudet, Daniel, Gipe, Daniel A., Pordy, Robert, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman K., Chyu, Kuang-Yuh, Sasiela, William J., Chan, Kuo-Chen, Brisson, Diane, Khoury, Etienne, Banerjee, Poulab

Journal:

New England Journal of Medicine

Year:

2017

Language:

english

File:

PDF, 73 KB

english, 2017

80

Safety and efficacy of evinacumab, a monoclonal antibody to ANGPTL3, in patients with homozygous familial hypercholesterolemia: a single-arm, open-label, proof-of-concept study

Gaudet, Daniel, Gipe, Daniel, Hovingh, Kees, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman, Chyu, Kuang -Yuh, Pordy, Robert, Sasiela, William, Chan, Kuo -Chen, Khoury, Etienne

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 53 KB

english, 2017

81

Cholesterol metabolism in humans

Millar, John S., Cuchel, Marina

Journal:

Current Opinion in Lipidology

Year:

2017

Language:

english

File:

PDF, 296 KB

english, 2017

82

Clinical, demographic and genetic characteristics of homozygous familial hypercholesterolemia patients worldwide: Interim results from the hofh international clinical collaborators (HICC) registry

Hartgers, M., Cuchel, M., Hovingh, G.K., Blom, D.J., Raal, F.J.

Journal:

Atherosclerosis

Year:

2018

Language:

english

File:

PDF, 53 KB

english, 2018

83

ATP binding cassette family A protein 1 determines hexosylceramide and sphingomyelin levels in human and mouse plasma

Iqbal, Jahangir, Walsh, Meghan T., Hammad, Samar M., Cuchel, Marina, Rader, Daniel J., Hussain, M. Mahmood

Journal:

The Journal of Lipid Research

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

84

JCL roundtable: High-density lipoprotein function and reverse cholesterol transport

Cuchel, Marina, Rohatgi, Anand, Sacks, Frank M., Guyton, John R.

Journal:

Journal of Clinical Lipidology

Year:

2018

Language:

english

File:

PDF, 342 KB

english, 2018

85

5938Efficacy of evinacumab in homozygous familial hypercholesterolemia patients with null or non-null LDL-receptor mutations and on various background therapies

Hovingh, G.K., Gipe, D.A., Ahmad, Z., Cuchel, M., Shah, P., Chyu, K.Y., Pordy, R., Sasiela, W.J., Chan, K.C., Khoury, E., Gaudet, D.

Journal:

European Heart Journal

Year:

2017

Language:

english

File:

PDF, 337 KB

english, 2017

86

The Role of High Density Lipoproteins in Thrombosis

Cuchel, Marina, Rader, Daniel J.

Journal:

The Scientific World JOURNAL

Year:

2002

Language:

english

File:

PDF, 1.05 MB

english, 2002

87

Is Low-Density Lipoprotein Cholesterol the Key to Interpret the Role of Lecithin:Cholesterol Acyltransferase in Atherosclerosis?

Vitali, Cecilia, Remaley, Alan T., Cuchel, Marina

Journal:

Year:

2018

Language:

english

File:

PDF, 294 KB

english, 2018

88

Homozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE-FH Registry†

Cuchel, Marina, Knowles, Joshua, Kindt, Iris, Shrader, Peter, Hudgins, Lisa, Duell, P., Shapiro, Michael, Rader, Daniel, de Ferranti, Sarah, Larry, John, Hemphill, Linda, Benuck, Irwin, Andersen, Rolf

Journal:

Journal of Clinical Lipidology

Year:

2019

Language:

english

File:

PDF, 90 KB

english, 2019

89

Homozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE-FH Registry†

Cuchel, Marina, Knowles, Joshua, Kindt, Iris, Shrader, Peter, Hudgins, Lisa, Duell, P., Shapiro, Michael, Rader, Daniel, de Ferranti, Sarah, Larry, John, Hemphill, Linda, Benuck, Irwin, Andersen, Rolf

Journal:

Journal of Clinical Lipidology

Year:

2019

File:

PDF, 90 KB

2019

90

Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop

Rodriguez, Annabelle, Trigatti, Bernardo L., Mineo, Chieko, Knaack, Darcy, Wilkins, John T., Sahoo, Daisy, Asztalos, Bela F., Mora, Samia, Cuchel, Marina, Pownall, Henry J., Rosales, Corina, Bernatche

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2019

Language:

english

File:

PDF, 207 KB

english, 2019

91

Literature Survey Of Lcat Deficiency: Natural History And Biomarker Identification

Bajaj, A., Vitali, C., Cuchel, M., Rader, D.

Journal:

Atherosclerosis

Year:

2019

Language:

english

File:

PDF, 51 KB

english, 2019

92

Lovastatin Decreases De Novo Cholesterol Synthesis and LDL Apo B-100 Production Rates in Combined-Hyperlipidemic Males

Cuchel, Marina, Schaefer, Ernst J., Millar, John S., Jones, Peter J.H., Dolnikowski, Gregory G., Vergani, Carlo, Lichtenstein, Alice H.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1997

Language:

english

File:

PDF, 818 KB

english, 1997

93

Homozygous familial hypercholesterolemia

Bajaj, Archna, Cuchel, Marina

Journal:

Current Opinion in Lipidology

Year:

2020

File:

PDF, 208 KB

2020

94

Hypoglycemia and Islet Dysfunction following Oral Glucose Tolerance Testing in Pancreatic Insufficient Cystic Fibrosis

Kilberg, Marissa J, Harris, Clea, Sheikh, Saba, Stefanovski, Darko, Cuchel, Marina, Kubrak, Christina, Hadjiliadis, Denis, Rubenstein, Ronald C, Rickels, Michael R, Kelly, Andrea

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2020

File:

PDF, 1.08 MB

2020

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