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51

Efficacy and safety of ezetimibe 40 mg vs. ezetimibe 10 mg in the treatment of patients with homozygous sitosterolaemia

T. Musliner, D. Cselovszky, W. Sirah, C. McCrary Sisk, A. Sapre, G. Salen, D. Lütjohann, K. Von Bergmann

Journal:

International Journal of Clinical Practice

Year:

2008

Language:

english

File:

PDF, 166 KB

english, 2008

52

Long-term efficacy and safety of ezetimibe 10 mg in patients with homozygous sitosterolemia: a 2-year, open-label extension study

D. Lütjohann, K. Von Bergmann, W. Sirah, G. Macdonell, A. O. Johnson-Levonas, A. Shah, J. Lin, A. Sapre, T. Musliner

Journal:

International Journal of Clinical Practice

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

53

Induction of Apoptosis and Necrosis in Human Neuroblastoma Cells by Cholesterol Oxides

MARIE LUISE RAO, DIETER LÜTJOHANN, MICHAEL LUDWIG, HEIKE KÖLSCH

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 2.09 MB

english, 1999

54

Pharmacokinetic and Pharmacodynamic Interactions Between the Immunosuppressant Sirolimus and the Lipid-Lowering Drug Ezetimibe in Healthy Volunteers

Oswald, S, Nassif, A, Modess, C, Keiser, M, Hanke, U, Engel, A, Lütjohann, D, Weitschies, W, Siegmund, W

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 156 KB

english, 2010

55

Plasma 4β-Hydroxycholesterol: An Endogenous CYP3A Metric?

Tomalik-Scharte, D, Lütjohann, D, Doroshyenko, O, Frank, D, Jetter, A, Fuhr, U

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 160 KB

english, 2009

56

Drug Interactions Between the Immunosuppressant Tacrolimus and the Cholesterol Absorption Inhibitor Ezetimibe in Healthy Volunteers

Oswald, S, Nassif, A, Modess, C, Keiser, M, Ulrich, A, Runge, D, Hanke, U, Lütjohann, D, Engel, A, Weitschies, W

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 161 KB

english, 2011

57

Associations of apolipoprotein E gene with ischemic stroke and intracranial atherosclerosis

Abboud, Shérine, Viiri, Leena E, Lütjohann, Dieter, Goebeler, Sirkka, Luoto, Teemu, Friedrichs, Silvia, Desfontaines, Philippe, Gazagnes, Marie-dominique, Laloux, Patrice, Peeters, André

Journal:

European Journal of Human Genetics

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

58

The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Aβ generation in vivo

Crameri, Arames, Biondi, Elisa, Kuehnle, Katrin, Lütjohann, Dieter, Thelen, Karin M, Perga, Simona, Dotti, Carlos G, Nitsch, Roger M, Ledesma, Maria Dolores, Mohajeri, M Hasan

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

59

Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer’s disease

Kölsch, H, Lütjohann, D, Ludwig, M, Schulte, A, Ptok, U, Jessen, F, von Bergmann, K, Rao, M L, Maier, W, Heun, R

Journal:

Molecular Psychiatry

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

60

Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease

Wollmer, M A, Streffer, J R, Tsolaki, M, Grimaldi, L M E, Lütjohann, D, Thal, D, von Bergmann, K, Nitsch, R M, Hock, C, Papassotiropoulos, A

Journal:

Molecular Psychiatry

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

61

Concentrations of Different Sterols in the Striatum and Serum of 3-Nitropropionic Acid-Treated Wistar and Lewis Rats

C.E. Teunissen, M. Mulder, J. de Vente, K. von Bergmann, C. De Bruijn, H.W.M. Steinbusch, D. Lütjohann

Journal:

Neurochemical Research

Year:

2001

Language:

english

File:

PDF, 48 KB

english, 2001

62

Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired -Cell Function

Kruit, J. K., Wijesekara, N., Westwell-Roper, C., Vanmierlo, T., de Haan, W., Bhattacharjee, A., Tang, R., Wellington, C. L., LutJohann, D., Johnson, J. D.

Journal:

Year:

2012

Language:

english

File:

PDF, 974 KB

english, 2012

63

Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease

Marcin Krawczyk, Dieter Lütjohann, Ramin Schirin-Sokhan, Luis Villarroel, Flavio Nervi, Fernando Pimentel, Frank Lammert, Juan Francisco Miquel

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

64

Cholesterol and Plant Sterol Absorption: Recent Insights

Klaus von Bergmann, Thomas Sudhop, Dieter Lütjohann

Journal:

The American Journal of Cardiology

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

65

Altered cholesterol metabolism in APP695-transfected neuroblastoma cells

Oliver Wirths, Karin M. Thelen, Dieter Lütjohann, Peter Falkai, Thomas A. Bayer

Journal:

Year:

2007

Language:

english

File:

PDF, 537 KB

english, 2007

66

CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk

Homeira Qureischie, Reinhard Heun, Dieter Lütjohann, Julius Popp, Frank Jessen, Christine Ledschbor-Frahnert, Holger Thiele, Wolfgang Maier, Frank Hentschel, Peter Kelemen, Heike Kölsch

Journal:

Year:

2008

Language:

english

File:

PDF, 230 KB

english, 2008

67

Decreased plasma cholesterol levels during aging in transgenic mouse models of Alzheimer's disease

Oliver Wirths, Karin Thelen, Henning Breyhan, Berta Luzón-Toro, Karl-Heinz Hoffmann, Peter Falkai, Dieter Lütjohann, Thomas A. Bayer

Journal:

Experimental Gerontology

Year:

2006

Language:

english

File:

PDF, 194 KB

english, 2006

68

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice

Kristiaan Wouters, Marc van Bilsen, Patrick J. van Gorp, Veerle Bieghs, Dieter Lütjohann, Anja Kerksiek, Bart Staels, Marten H. Hofker, Ronit Shiri-Sverdlov

Journal:

Year:

2010

Language:

english

File:

PDF, 323 KB

english, 2010

69

Plasma Plant Sterol Levels Do Not Reflect Cholesterol Absorption in Children with Smith-Lemli-Opitz Syndrome

Louise S. Merkens, Julia M. Jordan, Jennifer A. Penfield, Dieter Lütjohann, William E. Connor, Robert D. Steiner

Journal:

The Journal of Pediatrics

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

70

Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice

M. Oksman, H. Iivonen, E. Hogyes, Z. Amtul, B. Penke, I. Leenders, L. Broersen, D. Lütjohann, T. Hartmann, H. Tanila

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 362 KB

english, 2006

71

Changes in cerebral blood volume and amyloid pathology in aged Alzheimer APP/PS1 mice on a docosahexaenoic acid (DHA) diet or cholesterol enriched Typical Western Diet (TWD)

C.R. Hooijmans, F. Rutters, P.J. Dederen, G. Gambarota, A. Veltien, T. van Groen, L.M. Broersen, D. Lütjohann, A. Heerschap, H. Tanila, A.J. Kiliaan

Journal:

Neurobiology of Disease

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

72

DHA and cholesterol containing diets influence Alzheimer-like pathology, cognition and cerebral vasculature in APPswe/PS1dE9 mice

C.R. Hooijmans, C.E.E.M. Van der Zee, P.J. Dederen, K.M. Brouwer, Y.D. Reijmer, T. van Groen, L.M. Broersen, D. Lütjohann, A. Heerschap, A.J. Kiliaan

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 1.29 MB

english, 2009

73

Sterol transporters: targets of natural sterols and new lipid lowering drugs

Thomas Sudhop, Dieter Lütjohann, Klaus von Bergmann

Journal:

Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

74

Transfer of dietary plant sterols across the blood-brain barrier

P.J. Jansen, D. Lutjohann, T. Plosch, A.K. Groen, K. Abildayeva, F.C.S. Ramaekers, F. Kuipers, M. Mulder

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

75

The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells

Heike Kölsch, Dieter Lütjohann, Albert Tulke, Ingemar Björkhem, Marie Luise Rao

Journal:

Year:

1999

Language:

english

File:

PDF, 361 KB

english, 1999

76

24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia

A Papassotiropoulos, D Lütjohann, M Bagli, S Locatelli, F Jessen, R Buschfort, U Ptok, I Björkhem, K von Bergmann, R Heun

Journal:

Journal of Psychiatric Research

Year:

2002

Language:

english

File:

PDF, 185 KB

english, 2002

77

RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism

Heike Kölsch, Dieter Lütjohann, Frank Jessen, Julius Popp, Frank Hentschel, Peter Kelemen, Silvia Friedrichs, T.A. Wolfgang Maier, Reinhard Heun

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

78

Cholesterol dynamics in the foetal and neonatal brain as reflected by circulatory levels of 24S-hydroxycholesterol

D Lütjohann, I Björkhem, S Locatelli, C Dame, J Schmolling, K von Bergmann, H Fahnenstich

Journal:

Acta Paediatrica

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

79

Cholesterol Synthesis, Cholesterol Absorption, and Mortality in Hemodialysis Patients

Rogacev, K. S., Pinsdorf, T., Weingartner, O., Gerhart, M. K., Welzel, E., van Bentum, K., Popp, J., Menzner, A., Fliser, D., Lutjohann, D., Heine, G. H.

Journal:

Clinical Journal of the American Society of Nephrology

Year:

2012

Language:

english

File:

PDF, 751 KB

english, 2012

80

Dietary plant sterols accumulate in the brain

Paula J. Jansen, Dieter Lütjohann, Karlygash Abildayeva, Tim Vanmierlo, Torsten Plösch, Jogchum Plat, Klaus von Bergmann, Albert K. Groen, Frans C.S. Ramaekers, Folkert Kuipers, Monique Mulder

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

81

Alterations of cholesterol precursor levels in Alzheimer's disease

Heike Kölsch, Reinhard Heun, Frank Jessen, Julius Popp, Frank Hentschel, Wolfgang Maier, Dieter Lütjohann

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

82

Non-stereo-selective cytosolic human brain tissue 3-ketosteroid reductase is refractory to inhibition by AKR1C inhibitors

Stephan Steckelbroeck, Dieter Lütjohann, David R. Bauman, Michael Ludwig, Anke Friedl, Volkmar H.J. Hans, Trevor M. Penning, Dietrich Klingmüller

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 1.27 MB

english, 2010

83

Reduced brain cholesterol content in arylsulfatase A-deficient mice

Dieter Lütjohann, Klaus Harzer, Volkmar Gieselmann, Matthias Eckhardt

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 97 KB

english, 2006

84

Simvastatin prolongs survival times in prion infections of the central nervous system

Simon Wing Fai Mok, Karin M. Thelen, Constanze Riemer, Theresa Bamme, Sandra Gültner, Dieter Lütjohann, Michael Baier

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 2.45 MB

english, 2006

85

Effect of raloxifene and hormone therapy on serum markers of brain and whole-body cholesterol metabolism in postmenopausal women

Tatjana E. Vogelvang, Velja Mijatovic, Marius J. van der Mooren, Ursula Pinsdorf, Klaus von Bergmann, J. Coen Netelenbos, Dieter Lütjohann

Journal:

Year:

2005

Language:

english

File:

PDF, 94 KB

english, 2005

86

DHEA-Bodipy—A functional fluorescent DHEA analog for live cell imaging

Susanne Lemcke, Christoph Hönnscheidt, Gustav Waschatko, Anita Bopp, Dieter Lütjohann, Norbert Bertram, Katja Gehrig-Burger

Journal:

Molecular and Cellular Endocrinology

Year:

2010

Language:

english

File:

PDF, 1.44 MB

english, 2010

87

Does brain specific 24S-hydroxycholesterol in plasma indicate the disruption of the blood–brain barrier in patients with ischemic stroke?

Stefan Holdenrieder, Dieter Lütjohann, Sandra Geiger, Klaus von Bergmann, Petra Stieber, Gerhard F. Hamann

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 81 KB

english, 2004

88

Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients

H. Kölsch, R. Heun, A. Kerksiek, K.v. Bergmann, W. Maier, D. Lütjohann

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 133 KB

english, 2004

89

Influence of lysosomal acid lipase polymorphisms on chromosome 10 on the risk of Alzheimer's disease and cholesterol metabolism

K.-T. von Trotha, R. Heun, S. Schmitz, D. Lütjohann, W. Maier, H. Kölsch

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 93 KB

english, 2006

90

Cholesterol synthesis rate in human hippocampus declines with aging

K.M. Thelen, P. Falkai, T.A. Bayer, D. Lütjohann

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

91

PPARD haplotype influences cholesterol metabolism but is no risk factor of Alzheimer's disease

Julia Holzapfel, Reinhard Heun, Dieter Lütjohann, Frank Jessen, Wolfgang Maier, Heike Kölsch

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

92

Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals

Janka Koschack, Dieter Lütjohann, Carsten Schmidt-Samoa, Eva Irle

Journal:

Neurobiology of Aging

Year:

2009

Language:

english

File:

PDF, 128 KB

english, 2009

93

Total cholesterol and oxysterols: Early markers for cognitive decline in elderly?

T.N. van den Kommer, M.G. Dik, H.C. Comijs, K. Fassbender, D. Lütjohann, C. Jonker

Journal:

Neurobiology of Aging

Year:

2009

Language:

english

File:

PDF, 420 KB

english, 2009

94

The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline

Tessa N. van den Kommer, Miranda G. Dik, Hannie C. Comijs, Dieter Lütjohann, Paul Lips, Cees Jonker, Dorly J.H. Deeg

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 596 KB

english, 2012

95

Erratum to “Total Cholesterol and Oxysterols: Early Markers for Cognitive Decline in Elderly?” [Neurobiol. Aging 2009;30,534–545]

T.N. van den Kommer, M.G. Dik, H.C. Comijs, K. Fassbender, D. Lütjohann, C. Jonker

Journal:

Neurobiology of Aging

Year:

2011

File:

PDF, 281 KB

2011

96

Biological effects of oxidized phytosterols: A review of the current knowledge

Egbert Hovenkamp, Isabelle Demonty, Jogchum Plat, Dieter Lütjohann, Ronald P. Mensink, Elke A. Trautwein

Journal:

Progress in Lipid Research

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

97

High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs

Dieter Lütjohann, Mark Stroick, Thomas Bertsch, Sandra Kühl, Bernhard Lindenthal, Karin Thelen, Ulla Andersson, Ingemar Björkhem, Klaus von Bergmann, Klaus Fassbender

Journal:

Year:

2004

Language:

english

File:

PDF, 108 KB

english, 2004

98

Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo

Friedrich Felix Hoyer, Martin Steinmetz, Sebastian Zimmer, Astrid Becker, Dieter Lütjohann, Rainer Buchalla, Andreas Zimmer, Georg Nickenig

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 1.62 MB

english, 2011

99

On the origin of the cholestenoic acids in human circulation

Steve Meaney, Amir Babiker, Dieter Lütjohann, Ulf Diczfalusy, Magnus Axelson, Ingemar Björkhem

Journal:

Year:

2003

Language:

english

File:

PDF, 146 KB

english, 2003

100

KCNQ4, a Novel Potassium Channel Expressed in Sensory Outer Hair Cells, Is Mutated in Dominant Deafness

Christian Kubisch, Björn C Schroeder, Thomas Friedrich, Björn Lütjohann, Aziz El-Amraoui, Sandrine Marlin, Christine Petit, Thomas J Jentsch

Journal:

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999