D. Selkoe: search on Z-Library

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101

Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase

Esler, William P., Das, Chittaranjan, Campbell, William A., Kimberly, W. Taylor, Kornilova, Anna Y., Diehl, Thekla S., Ye, Wenjuan, Ostaszewski, Beth L., Xia, Weiming, Selkoe, Dennis J.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 465 KB

english, 2002

102

Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases

Selkoe, Dennis J.

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 341 KB

english, 2004

103

The ups and downs of Aβ

Selkoe, Dennis J

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 455 KB

english, 2006

104

Alzheimer's amyloid of another flavour

Selkoe, Dennis J.

Journal:

Nature Medicine

Year:

1995

File:

PDF, 440 KB

1995

105

Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo

Klyubin, Igor, Walsh, Dominic M, Lemere, Cynthia A, Cullen, William K, Shankar, Ganesh M, Betts, Vicki, Spooner, Edward T, Jiang, Liying, Anwyl, Roger, Selkoe, Dennis J

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 486 KB

english, 2005

106

The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

Haass, Christian, Lemere, Cynthia A., Capell, Anja, Citron, Martin, Seubert, Peter, Schenk, Dale, Lannfelt, Lars, Selkoe, Dennis J.

Journal:

Nature Medicine

Year:

1995

File:

PDF, 865 KB

1995

107

Dopamine covalently modifies and functionally inactivates parkin

LaVoie, Matthew J, Ostaszewski, Beth L, Weihofen, Andreas, Schlossmacher, Michael G, Selkoe, Dennis J

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 324 KB

english, 2005

108

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide

Haass, Christian, Selkoe, Dennis J.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2007

Language:

english

File:

PDF, 677 KB

english, 2007

109

Aging Brain, Aging Mind

Selkoe, Dennis J.

Journal:

Scientific American

Year:

1992

Language:

english

File:

PDF, 1.14 MB

english, 1992

110

Amyloid Protein and Alzheimer's Disease

Selkoe, Dennis J.

Journal:

Scientific American

Year:

1991

Language:

english

File:

PDF, 911 KB

english, 1991

111

Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: a potent role for trimers

Matthew Townsend, Ganesh M. Shankar, Tapan Mehta, Dominic M. Walsh, Dennis J. Selkoe

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 487 KB

english, 2006

112

The APP family of proteins: similarities and differences

Walsh, D.M., Minogue, A.M., Sala Frigerio, C., Fadeeva, J.V., Wasco, W., Selkoe, D.J.

Journal:

Biochemical Society Transactions

Year:

2007

Language:

english

File:

PDF, 216 KB

english, 2007

113

[Research and Perspectives in Alzheimer's Disease] Synaptic Plasticity and the Mechanism of Alzheimer's Disease Volume 6 || Soluble Oligomers of the Amyloid β-Protein: Impair Synaptic Plasticity and Behavior

Selkoe, Dennis J., Triller, Antoine, Christen, Yves

Year:

2008

Language:

english

File:

PDF, 310 KB

english, 2008

114

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

Bartels, Tim, Choi, Joanna G., Selkoe, Dennis J.

Journal:

Year:

2011

Language:

english

File:

PDF, 413 KB

english, 2011

115

γ-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons

Aedín M. Minogue, Adam K. Stubbs, Carlo Sala Frigerio, Barry Boland, Julia V. Fadeeva, Jordan Tang, Dennis J. Selkoe, Dominic M. Walsh

Journal:

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

116

Small non-fibrillar assemblies of amyloid β-protein bearing the Arctic mutation induce rapid neuritic degeneration

Brian M. Whalen, Dennis J. Selkoe, Dean M. Hartley

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 1.75 MB

english, 2005

117

Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid β-protein metabolism in mouse models of Alzheimer disease

Matthew L. Hemming, Dennis J. Selkoe, Wesley Farris

Journal:

Neurobiology of Disease

Year:

2007

Language:

english

File:

PDF, 884 KB

english, 2007

118

LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model

Babak Nazer, Soyon Hong, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

2008

Language:

english

File:

PDF, 795 KB

english, 2008

119

Aggregation and catabolism of disease-associated intra-Aβ mutations: reduced proteolysis of AβA21G by neprilysin

Vicki Betts, Malcolm A. Leissring, Georgia Dolios, Rong Wang, Dennis J. Selkoe, Dominic M. Walsh

Journal:

Neurobiology of Disease

Year:

2008

Language:

english

File:

PDF, 756 KB

english, 2008

120

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life

Ganesh M. Shankar, Malcolm A. Leissring, Anthony Adame, Xiaoyan Sun, Edward Spooner, Eliezer Masliah, Dennis J. Selkoe, Cynthia A. Lemere, Dominic M. Walsh

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

121

Plasma C-peptide levels and rates of cognitive decline in older, community-dwelling women without diabetes

Olivia I. Okereke, Michael N. Pollak, Frank B. Hu, Susan E. Hankinson, Dennis J. Selkoe, Francine Grodstein

Journal:

Psychoneuroendocrinology

Year:

2008

Language:

english

File:

PDF, 244 KB

english, 2008

122

Toward Structural Elucidation of the γ-Secretase Complex

Huilin Li, Michael S. Wolfe, Dennis J. Selkoe

Journal:

Year:

2009

Language:

english

File:

PDF, 628 KB

english, 2009

123

The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease

Dennis J Selkoe

Journal:

Trends in Cell Biology

Year:

1998

Language:

english

File:

PDF, 418 KB

english, 1998

124

Presenilins, β-amyloid precursor protein and the molecular basis of Alzheimer's disease

Dennis J. Selkoe

Journal:

Clinical Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 276 KB

english, 2001

125

α-Synuclein Neuropathology is Controlled by Nuclear Hormone Receptors and Enhanced by Docosahexaenoic Acid in A Mouse Model for Parkinson's Disease

Eugenia Yakunin, Virginie Loeb, Haya Kisos, Yoav Biala, Shlomo Yehuda, Yoel Yaari, Dennis J. Selkoe, Ronit Sharon

Journal:

Brain Pathology

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

126

Preventing Alzheimer's Disease

Journal:

Year:

2012

Language:

english

File:

PDF, 558 KB

english, 2012

127

Alzheimer's Disease Is a Synaptic Failure

Journal:

Year:

2002

Language:

english

File:

PDF, 222 KB

english, 2002

128

Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing

Anja Leona Biere, Beth Ostaszewski, Hongwei Zhao, Susan Gillespie, Steven G. Younkin, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1995

Language:

english

File:

PDF, 576 KB

english, 1995

129

Permeability and Residual Plasma Volume of Human, Dutch Variant, and Rat Amyloid β-Protein 1-40 at the Blood–Brain Barrier

Joseph F. Poduslo, Geoffry L. Curran, Jill J. Haggard, Anja Leona Biere, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1997

Language:

english

File:

PDF, 232 KB

english, 1997

130

Sequence of Deposition of Heterogeneous Amyloid β-Peptides and APO E in Down Syndrome: Implications for Initial Events in Amyloid Plaque Formation

C.A. Lemere, J.K. Blusztajn, H. Yamaguchi, T. Wisniewski, T.C. Saido, D.J. Selkoe

Journal:

Neurobiology of Disease

Year:

1996

Language:

english

File:

PDF, 568 KB

english, 1996

131

Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein

Martin Citron, Christopher B. Eckman, Thekla S. Diehl, Chris Corcoran, Beth L. Ostaszewski, Weiming Xia, Georges Levesque, Peter St. George Hyslop, Steven G. Younkin, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1998

Language:

english

File:

PDF, 315 KB

english, 1998

132

Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain

Diane T. Stephenson, Cynthia A. Lemere, Dennis J. Selkoe, James A. Clemens

Journal:

Neurobiology of Disease

Year:

1996

Language:

english

File:

PDF, 405 KB

english, 1996

133

Receptor-Mediated Transport of Human Amyloid β-Protein 1–40 and 1–42 at the Blood–Brain Barrier

Joseph F. Poduslo, Geoffry L. Curran, Bharati Sanyal, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1999

Language:

english

File:

PDF, 146 KB

english, 1999

134

FAD Mutations in Presenilin-1 or Amyloid Precursor Protein Decrease the Efficacy of a γ-Secretase Inhibitor: Evidence for Direct Involvement of PS1 in the γ-Secretase Cleavage Complex

Weiming Xia, Beth L. Ostaszewski, W.Taylor Kimberly, Talat Rahmati, Chad L. Moore, Michael S. Wolfe, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 170 KB

english, 2000

135

Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease

Stefan Bodmer, Marcia Berman Podlisny, Dennis J. Selkoe, Irma Heid, Adriano Fontana

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 1.29 MB

english, 1990

136

Protein chemical and immunocytochemical studies of meningovascular β-amyloid protein in Alzheimer's disease and normal aging

Catharine L. Joachim, Lawrence K. Duffy, James H. Morris, Dennis J. Selkoe

Journal:

Year:

1988

Language:

english

File:

PDF, 3.96 MB

english, 1988

137

Amino-terminal region of the β-amyloid precursor protein activates mitogen-activated protein kinase

Steven M. Greenberg, Wei Qiao Qiu, Dennis J. Selkoe, Anina Ben-Itzhak, Kenneth S. Kosik

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 482 KB

english, 1995

138

Generation of amyloid β protein from its precursor is sequence specific

Martin Citron, David B Teplow, Dennis J Selkoe

Journal:

Year:

1995

Language:

english

File:

PDF, 2.39 MB

english, 1995

139

Disease, transplantation and regeneration

Martin Schwab, Dennis Selkoe

Journal:

Current Opinion in Neurobiology

Year:

1995

Language:

english

File:

PDF, 249 KB

english, 1995

140

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

Dennis J. Selkoe

Journal:

Behavioural Brain Research

Year:

2008

Language:

english

File:

PDF, 200 KB

english, 2008

141

Presenilin: Running with Scissors in the Membrane

Dennis J. Selkoe, Michael S. Wolfe

Journal:

Year:

2007

Language:

english

File:

PDF, 504 KB

english, 2007

142

Giving Alzheimer's the Old One-Two

Michael S. Wolfe, Dennis J. Selkoe

Journal:

Year:

2010

Language:

english

File:

PDF, 662 KB

english, 2010

143

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J. LaVoie, Thomas L. Schwarz

Journal:

Year:

2011

Language:

english

File:

PDF, 2.15 MB

english, 2011

144

Secreted amyloid beta and impaired neurotrophin transport: Potential mediators of abnormal cns development and neurodegeneration in down syndrome

M.T. Maloney, C. Wu, R.C. Davis, L.S. Minamide, M. Podlisny, D.J. Selkoe

Journal:

International Journal of Developmental Neuroscience

Year:

2010

Language:

english

File:

PDF, 75 KB

english, 2010

145

Cryoelectron Microscopy Structure of Purified γ-Secretase at 12 Å Resolution

Pamela Osenkowski, Hua Li, Wenjuan Ye, Dongyang Li, Lorene Aeschbach, Patrick C. Fraering, Michael S. Wolfe, Dennis J. Selkoe, Huilin Li

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

146

Amyloid β-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-d-aspartate (NMDA) versus non-NMDA receptor/channel activation

Chianping Ye, Dominic M Walsh, Dennis J Selkoe, Dean M Hartley

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 259 KB

english, 2004

147

Aβ oligomers inhibit synapse remodelling necessary for memory consolidation

Darragh B. Freir, Rocio Fedriani, Darren Scully, Imelda M. Smith, Dennis J. Selkoe, Dominic M. Walsh, Ciaran M. Regan

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

148

Recommendations for the incorporation of biomarkers into Alzheimer clinical trials: an overview

John C. Morris, Dennis J. Selkoe

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 350 KB

english, 2011

149

Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease

Dominic M. Walsh, Dennis J. Selkoe

Journal:

Year:

2004

Language:

english

File:

PDF, 290 KB

english, 2004

150

Response to: Pardossi-Piquard et al., “Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP.” Neuron 46, 541–554

Allen C. Chen, Dennis J. Selkoe

Journal:

Year:

2007

Language:

english

File:

PDF, 564 KB

english, 2007

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