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51

Endocytosis-independent uptake of liposome-encapsulated superoxide dismutase prevents the killing of cultured hepatocytes by tert-butyl hydroperoxide

Dai Nakae, Hitoshi Yoshiji, Toshihiro Amanuma, Tetsuo Kinugasa, John L. Farber, Yoichi Konishi

Journal:

Archives of Biochemistry and Biophysics

Year:

1990

Language:

english

File:

PDF, 547 KB

english, 1990

52

Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen

Marlene E. Kyle, Stefania Miccadei, Dai Nakae, John L. Farber

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 489 KB

english, 1987

53

Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide

Marlene E. Kyle, Dai Nakae, Isao Sakaida, Ada Serroni, John L. Farber

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 827 KB

english, 1989

54

Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue

Dai Nakae, Yasushi Mizumoto, Eisaku Kobayashi, Osamu Noguchi, Yoichi Konishi

Journal:

Year:

1995

Language:

english

File:

PDF, 632 KB

english, 1995

55

Inhibition of the development of hepatocellular carcinomas by phenyl N-tert-butyl nitrone in rats fed with a choline-deficient, l-amino acid-defined diet

Dai Nakae, Fumiyuki Uematsu, Hideki Kishida, Osamu Kusuoka, Shin-ichi Katsuda, Midori Yoshida, Masakazu Takahashi, Akihiko Maekawa, Ayumi Denda, Yoichi Konishi, Yashige Kotake, Robert A Floyd

Journal:

Year:

2004

Language:

english

File:

PDF, 491 KB

english, 2004

56

Effects of estrogens and metabolites on endometrial carcinogenesis in young adult mice initiated with N-ethyl-N′-nitro-N-nitrosoguanidine

Masakazu Takahashi, Takasumi Shimomoto, Katsuhiro Miyajima, Midori Yoshida, Sayumi Katashima, Fumiyuki Uematsu, Akihiko Maekawa, Dai Nakae

Journal:

Year:

2004

Language:

english

File:

PDF, 280 KB

english, 2004

57

Lack of toxicity or carcinogenicity of S-170, a sucrose fatty acid ester, in F344 rats

Midori Yoshida, Shin-ichi Katsuda, Dai Nakae, Akihiko Maekawa

Journal:

Food and Chemical Toxicology

Year:

2004

Language:

english

File:

PDF, 342 KB

english, 2004

58

Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol

Masayoshi Abe, Noriko Suzuki, Midori Yoshida, Koji Usuda, Satoshi Furukawa, Lekh Raj Juneja, Tsutomu Okubo, Dai Nakae

Journal:

Food and Chemical Toxicology

Year:

2008

Language:

english

File:

PDF, 501 KB

english, 2008

59

Parenteral paradichlorobenzene exposure reduces sperm production, alters sperm morphology and exhibits an androgenic effect in rats and mice

Osamu Takahashi, Norio Ohashi, Dai Nakae, Akio Ogata

Journal:

Food and Chemical Toxicology

Year:

2011

Language:

english

File:

PDF, 886 KB

english, 2011

60

Effect of La on the wettability of Al2O3 by molten aluminum

N Shao, J.W Dai, G.Y Li, H Nakae, T Hane

Journal:

Materials Letters

Year:

2004

Language:

english

File:

PDF, 234 KB

english, 2004

61

Differentiation of induced pluripotent stem cells from ALS patients generates motor neurons

Shiho Kitaoka, Haruhisa Inoue, Kayoko Tsukita, Mitsuyo Kawada, Motoko Naitoh, Kazutoshi Takahashi, Katsuhiro Yoshikawa, Takayuki Kondo, Satoko Yamawaki, Dai Watanabe, Shigehiko Suzuki, Tatsutoshi Naka

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 84 KB

english, 2010

62

Expression of inducible nitric oxide (NO) synthase but not prevention by its gene ablation of hepatocarcinogenesis with fibrosis caused by a choline-deficient, l-amino acid-defined diet in rats and mice

Ayumi Denda, Wakashi Kitayama, Hideki Kishida, Nao Murata, Kazutoshi Tamura, Osamu Kusuoka, Masahiro Tsutsumi, Fumiko Nishikawa, Eiji Kita, Dai Nakae, Yoichi Konishi, Hiroki Kuniyasu

Journal:

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

63

Dimethylarsinic acid induces 8-hydroxy-2′-deoxyguanosine formation in the kidney of NCI-Black-Reiter rats

Meenakshi Vijayaraghavan, Hideki Wanibuchi, Rezaul Karim, Shinji Yamamoto, Chikayoshi Masuda, Dai Nakae, Yoichi Konishi, Shoji Fukushima

Journal:

Year:

2001

Language:

english

File:

PDF, 228 KB

english, 2001

64

Lack of promoting effect due to oral administration of dimethylarsinic acid on rat lung carcinogenesis initiated with N-bis(2-hydroxypropyl)nitrosamine

Noritaka Seike, Hideki Wanibuchi, Keiichirou Morimura, Takayuki Nishikawa, Hideki Kishida, Dai Nakae, Kazuto Hirata, Shoji Fukushima

Journal:

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

65

Inhibitory effects of lemon grass (Cymbopogon citratus, Stapf) extract on the early phase of hepatocarcinogenesis after initiation with diethylnitrosamine in male Fischer 344 rats

Rawiwan Puatanachokchai, Hideki Kishida, Ayumi Denda, Nao Murata, Yoichi Konishi, Usanee Vinitketkumnuen, Dai Nakae

Journal:

Year:

2002

Language:

english

File:

PDF, 78 KB

english, 2002

66

Lack of initiation activity in rat liver of low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Shoji Fukushima, Hideki Wanibuchi, Keiichirou Morimura, Min Wei, Dai Nakae, Yoichi Konishi, Hiroyuki Tsuda, Nobuo Takasuka, Katsumi Imaida, Tomoyuki Shirai, Masae Tatematsu, Tetsuya Tsukamoto, Masao H

Journal:

Year:

2003

Language:

english

File:

PDF, 101 KB

english, 2003

67

Infrequent Ki-ras and an absence of p53 mutations in hepatocellular carcinomas induced by a choline deficient l-amino acid defined diet in rats

Toshifumi Tsujiuchi, Akira Kido, Dai Nakae, Makoto Takahama, Toshimitsu Majima, Kunihiko Kobitsu, Eijiro Okajima, Masahiro Tsutsumi, Ayumi Denda, Yoichi Konishi

Journal:

Year:

1996

Language:

english

File:

PDF, 482 KB

english, 1996

68

Increased telomerase activity and absence of p53 mutation in oligo-astrocytomas induced by N-ethyl-N-nitrosourea in rats

Hiroyuki Sakitani, Toshifumi Tsujiuchi, Kunihiko Kobitsu, Akira Kido, Katsumichi Iki, Makoto Takahama, Mitsuhiro Nakamura, Toshisuke Sakaki, Dai Nakae, Yoichi Konishi, Masahiro Tsutsumi

Journal:

Year:

1998

Language:

english

File:

PDF, 251 KB

english, 1998

69

Increased telomerase activity in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters

Katsumichi Iki, Toshifumi Tsujiuchi, Toshimitsu Majima, Hiroyuki Sakitani, Masahiro Tsutsumi, Makoto Takahama, Masatoshi Yoshimoto, Dai Nakae, Tsukasa Tsunoda, Yoichi Konishi

Journal:

Year:

1998

Language:

english

File:

PDF, 69 KB

english, 1998

70

Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice

Midori Yoshida, Katsuhiro Miyajima, Katsuhisa Shiraki, Jin Ando, Kayoko Kudoh, Dai Nakae, Masakazu Takahashi, Akihiko Maekawa

Journal:

Year:

1999

Language:

english

File:

PDF, 708 KB

english, 1999

71

Genotoxicity of multi-walled carbon nanotubes in both in vitro and in vivo assay systems

Kato, Tatsuya, Totsuka, Yukari, Ishino, Kousuke, Matsumoto, Yoko, Tada, Yukie, Nakae, Dai, Goto, Sumio, Masuda, Shuichi, Ogo, Sayaka, Kawanishi, Masanobu, Yagi, Takashi, Matsuda, Tomonari, Watanabe, M

Journal:

Year:

2013

Language:

english

File:

PDF, 666 KB

english, 2013

72

Effects of oxidative stress induced by redox-enzyme modulation on rat hepatocarcinogenesis

Ayumi Denda, Takehiro Endoh, Dai Nakae, Yoichi Konishi

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 434 KB

english, 1995

73

Production of Both 8-Hydroxydeoxyguanosine in Liver DNA and γ-Glutamyltransferase-positive Hepatocellular Lesions in Rats Given a Choline-deficient, l-Amino Acid-defined Diet

Dai Nakae, Hitoshi Yoshiji, Hiroshi Maruyama, Tetsuo Kinugasa, Ayumi Denda, Yoichi Konishi

Journal:

Year:

1990

File:

PDF, 242 KB

1990

74

Prevention by Methionine of Enhancement of Hepatocarcinogenesis by Coadministration of a Choline-deficient L-Amino Acid-defined Diet and Ethionine in Rats

Toshifumi Tsujiuchi, Eisaku Kobayashi, Dai Nakae, Yasushi Mizumoto, Nobuaki Andoh, Hiromichi Kitada, Kazuo Ohashi, Tomokazu Fukuda, Akira Kido, Masahiro Tsutsumi, Ayumi Denda, Yoichi Konishi

Journal:

Year:

1995

File:

PDF, 424 KB

1995

75

Clinical characteristics and proliferating activity of intrahepatic cholangiocarcinoma

KAZUO OHASHI, YOSHIYUKI NAKAJIMA, MASAHIRO TSUTSUMI, HIROMICHI KANEHIRO, TOSHIYUKI FUKUOKA, MICHIYOSHI HISANAGA, JUNICHIRO TAKI, DAI NAKAE, YOICHI KONISHI, HIROSHIGE NAKANO

Journal:

Journal of Gastroenterology and Hepatology

Year:

1994

Language:

english

File:

PDF, 845 KB

english, 1994

76

Reproductive and Neurobehavioral Effects of Brilliant Blue FCF in Mice

Tanaka, Toyohito, Takahashi, Osamu, Inomata, Akiko, Ogata, Akio, Nakae, Dai

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 542 KB

english, 2012

77

High-temperature calcined fullerene nanowhiskers and multi-wall carbon nanotubes have abilities to induce IL-1beta secretion through NLRP3-dependent mechanism, depending on their lengths

Nishimaki-Mogami, Tomoko, Cui, Hongyan, Wu, Weija, Okuhira, Keiichiro, Naito, Mikihiko, Nishimura, Tetsuji, Sakamoto, Yoshimitsu, Ogata, Akio, Maeno, Tomokazu, Inomata, Akiko, Nakae, Dai, Miyazawa, Ku

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 82 KB

english, 2013

78

Selective 8-hydroxyguanine formation in pancreatic DNA due to a single intravenous administration of 4-hydroxyaminoquinoline l-oxide in rats

Nakae, Dai, Andoh, Nobuaki, Mizumoto, Yasushi, Endoh, Takehiro, Shimoji, Naoshi, Horiguchi, Kohsuke, Shiraiwa, Kazumi, Tamura, Kazutoshi, Denda, Ayumi, Konishi, Yoichi

Journal:

Year:

1994

Language:

english

File:

PDF, 600 KB

english, 1994

79

Multi-step lung carcinogenesis model induced by oral administration of N-nitrosobis(2-hydroxypropyl)amine in rats

Tsujiuchi, Toshifumi, Nakae, Dai, Konishi, Yoichi

Journal:

Experimental and Toxicologic Pathology

Year:

2014

Language:

english

File:

PDF, 969 KB

english, 2014

80

Persistent effect of a low dose of preadministered diethylnitrosamine on the induction of enzyme-altered foci in rat liver

Takahashi, Seiichi, Tsutsumi, Masahiro, Nakae, Dai, Denda, Ayumi, Kinugasa, Tetsuo, Konishi, Yoichi

Journal:

Year:

1987

Language:

english

File:

PDF, 3.31 MB

english, 1987

81

Rapid identification of a narcotic plantPapaver bracteatumusing flow cytometry

Aragane, Masako, Watanabe, Daisuke, Nakajima, Jun’ichi, Yoshida, Masao, Yoshizawa, Masao, Abe, Tomohiro, Nishiyama, Rei, Suzuki, Jin, Moriyasu, Takako, Nakae, Dai, Sudo, Hiroshi, Sato, Hiroyuki, Hishi

Journal:

Journal of Natural Medicines

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

82

Effects of Maternal Exposure to Imazalil on Behavioral Development in F 1 -Generation Mice

Tanaka, Toyohito, Ogata, Akio, Inomata, Akiko, Nakae, Dai

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2013

Language:

english

File:

PDF, 769 KB

english, 2013

83

Structure-dependent inhibitory effects of synthetic cannabinoids against 12- O -tetradecanoylphorbol-13-acetate-induced inflammation and skin tumour promotion in mice

Nakajima, Jun'ichi, Nakae, Dai, Yasukawa, Ken

Journal:

Journal of Pharmacy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 519 KB

english, 2013

84

Occurrence and behavior of the chiral anti-inflammatory drug naproxen in an aquatic environment

Suzuki, Toshinari, Kosugi, Yuki, Hosaka, Mitsugu, Nishimura, Tetsuji, Nakae, Dai

Journal:

Environmental Toxicology and Chemistry

Year:

2014

Language:

english

File:

PDF, 976 KB

english, 2014

85

Prevention by acetylsailcylic acid of liver cirrhosis and carcinogenesis as well as generations of 8-hydroxydeoxyguanosine and thiobarbituric acid-reactive substances caused by a choline-deficient, L-amino acid-defined diet in rats

Denda, Ayumi, Tang, Qing, Endoh, Takehiro, Tsujiuchi, Toshifumi, Horiguchi, Kohsuke, Noguchi, Osamu, Mizumoto, Yasushi, Nakae, Dai, Konishi, Yoichi

Journal:

Year:

1994

Language:

english

File:

PDF, 1.63 MB

english, 1994

86

Effects of oxidative stress induced by redox-enzyme modulation on the progression stage of rat hepatocarcinogenesis

Denda, Ayumi, Tang, Qing, Tsujiuchi, Toshifumi, Tsutsumi, Masahiro, Amanuma, Toshihiro, Murata, Yoshiharu, Tamura, Kazutoshi, Horiguchi, Konsuke, Nakae, Dai, Konishi, Yoichi

Journal:

Year:

1993

Language:

english

File:

PDF, 2.21 MB

english, 1993

87

Chronic Toxicity and Carcinogenicity Studies of 2-Methylnaphthalene in B6C3F 1 Mice

MURATA, YOSHIAKI, DENDA, AYUMI, MARUYAMA, HIROSHI, NAKAE, DAI, TSUTSUMI, MASAHIRO, TSUJIUCHI, TOSHIFUMI, KONISHI, YOICHI

Journal:

Toxicological Sciences

Year:

1997

Language:

english

File:

PDF, 340 KB

english, 1997

88

A Case Report of a Choroid Plexus Carcinoma Spontaneously Occurring in the Right Lateral Ventricle of a 14-Week-Old, Female Donryu Rat

SHIMOMOTO, TAKASUMI, YOSHIDA, MIDORI, TAKAHASHI, MASAKAZU, UEMATSU, FUMIYUKI, MAEKAWA, AKIHIKO, NAKAE, DAI

Journal:

Toxicologic Pathology

Year:

2004

Language:

english

File:

PDF, 463 KB

english, 2004

89

Inhibition by acetylsalicylic acid, a cyclo-oxygenase inhibitor, and p-bromophenacylbromide, a phospholipase A 2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats

Endoh, Takehiro, Tang, Qing, Denda, Ayumi, Noguchi, Osamu, Kobayashi, Eisaku, Tamura, Kazutoshi, Horiguchi, Kohsuke, Ogasawara, Hiroyuki, Tsujiuchi, Toshifumi, Nakae, Dai, Sugimura, Masahito, Konishi,

Journal:

Year:

1996

Language:

english

File:

PDF, 4.18 MB

english, 1996

90

Lack of hepatocarcinogenic potential of acetaminophen in rats with liver damage associated with a choline-devoid diet

Maruyama, Hiroshi, Takashima, Yoshiharu, Murata, Yoshiaki, Nakae, Dai, Eimoto, Hiroyuki, Tsutsumi, Masahiro, Denda, Ayumi, Konishi, Yoichi

Journal:

Year:

1990

Language:

english

File:

PDF, 5.55 MB

english, 1990

91

Long-term Pulmonary Responses to Quadweekly Intermittent Intratracheal Spray Instillations of Magnetite (Fe3O4) Nanoparticles for 52 Weeks in Fischer 344 Rats

Tada, Yukie, Yano, Norio, Takahashi, Hiroshi, Yuzawa, Katsuhiro, Ando, Hiroshi, Kubo, Yoshikazu, Nagasawa, Akemichi, Inomata, Akiko, Ogata, Akio, Nakae, Dai

Journal:

Journal of Toxicologic Pathology

Year:

2013

Language:

english

File:

PDF, 4.87 MB

english, 2013

92

Pancreatic Ductal Adenocarcinoma in a Wistar Hannover GALAS Rat

Kuroda, Yusuke, Hayashi, Seigo, Hagio, Soichiro, Abe, Masayoshi, Furukawa, Satoshi, Nakae, Dai

Journal:

Journal of Toxicologic Pathology

Year:

2014

Language:

english

File:

PDF, 2.77 MB

english, 2014

93

Acute Phase Pulmonary Responses to a Single Intratracheal Spray Instillation of Magnetite (Fe3O4) Nanoparticles in Fischer 344 Rats

Tada, Yukie, Yano, Norio, Takahashi, Hiroshi, Yuzawa, Katsuhiro, Ando, Hiroshi, Kubo, Yoshikazu, Nagasawa, Akemichi, Ogata, Akio, Nakae, Dai

Journal:

Journal of Toxicologic Pathology

Year:

2012

Language:

english

File:

PDF, 2.93 MB

english, 2012

94

In vitro effects induced by diesel exhaust at an air–liquid interface in a human lung alveolar carcinoma cell line A549

Okubo, Tomoko, Hosaka, Mitsugu, Nakae, Dai

Journal:

Experimental and Toxicologic Pathology

Year:

2015

Language:

english

File:

PDF, 744 KB

english, 2015

95

Inhibitory effect of dietary iron deficiency on inductions of putative preneoplastic lesions as well as 8-hydroxydeoxyguanosine in DNA and lipid peroxidation in the livers of rats caused by exposure to a choline-deficient L-amino acid defined diet

Yoshiji, Hitoshi, Nakae, Dai, Mizumoto, Yasushi, Horiguchi, Kohsuke, Tamura, Kazutoshi, Denda, Ayumi, Tsujii, Tadasu, Konishi, Yoichi

Journal:

Year:

1992

Language:

english

File:

PDF, 673 KB

english, 1992

96

Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver

Denda, Ayumi, Sai, Kimie, Tang, Qing, Tsujiuchi, Toshifumi, Tsutsumi, Masahiro, Amanuma, Toshihiro, Murata, Yoshiharu, Nakae, Dai, Maruyama, Hiroshi, Kurokawa, Yuji, Konishi, Yoichi

Journal:

Year:

1991

Language:

english

File:

PDF, 5.35 MB

english, 1991

97

Interleukin-15 Expression Is Associated with Malignant Potential in Colon Cancer Cells

Kuniyasu, Hiroki, Oue, Naohide, Nakae, Dai, Tsutsumi, Masahiro, Denda, Ayumi, Tsujiuchi, Toshifumi, Yokozaki, Hiroshi, Yasui, Wataru

Journal:

Year:

2001

Language:

english

File:

PDF, 490 KB

english, 2001

98

Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD + ADP ribosyl transferase in rats

Takahashi, Seiichi, Nakae, Dai, Yokose, Yoshihiko, Emi, Yohko, Denda, Ayumi, Mikami, Shuji, Ohnishi, Takeo, Konishi, Yoichi

Journal:

Year:

1984

Language:

english

File:

PDF, 641 KB

english, 1984

99

Effects of catechol and its analogs on pancreatic carcinogenesis initiated by N -nitrosobis(2-oxopropyl)amine in Syrian hamsters

Maruyama, Hiroshi, Amanuma, Toshihiro, Nakae, Dai, Tsutsumi, Masahiro, Kondo, Satoshi, Tsujiuchi, Toshifumi, Denda, Ayumi, Konishi, Yoichi

Journal:

Year:

1991

Language:

english

File:

PDF, 379 KB

english, 1991

100

Possible enhancing effect of the immunosuppressive agent, 6-mercaptopurine(6-MP) on focal lesion development in cirrhotic liver induced by carbon tetrachloride but not furfural in F344 rats

Maruyama, Hiroshi, Amanuma, Toshihiro, Takashima, Yoshiharu, Yoshiji, Hitoshi, Nakae, Dai, Tsutsumi, Masahiro, Tsujiuchi, Toshifumi, Denda, Ayumi, Konishi, Yoichi

Journal:

Year:

1992

Language:

english

File:

PDF, 440 KB

english, 1992