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51

Uridylate Trapping Induced by the C-2-Modified d-Glucose Analogs Glucosone, Fluoroglucose, and Glucosamine

Axel HOLSTEGE, Christa SCHULZ-HOLSTEGE, Hanspeter HENNINGER, Karl A. REIFFEN, Friedhelm SCHNEIDER, Dietrich O. R. KEPPLER

Journal:

Year:

1982

Language:

english

File:

PDF, 678 KB

english, 1982

52

Dual Role of Hexose-1-phosphate Uridylyltransferase in Galactosamine Metabolism

Gisbert WECKBECKER, Dietrich O. R. KEPPLER

Journal:

Year:

1982

Language:

english

File:

PDF, 592 KB

english, 1982

53

Leukotriene C4 metabolism by hepatoma cells deficient in the uptake of cysteinyl leukotrienes

Gisbert WECKBECKER, Dietrich O. R. KEPPLER

Journal:

Year:

1986

Language:

english

File:

PDF, 394 KB

english, 1986

54

Inhibition of leukotriene D4 catabolism by D-penicillamine

Michael HUBER, Dietrich KEPPLER

Journal:

Year:

1987

Language:

english

File:

PDF, 670 KB

english, 1987

55

Ethanol-induced inhibition of leukotriene degradation by ω-oxidation

Thomas BAUMERT, Michael HUBER, Doris MAYER, Dietrich KEPPLER

Journal:

Year:

1989

Language:

english

File:

PDF, 647 KB

english, 1989

56

Direct photoaffinity labeling of leukotriene binding sites

Eugen FALK, Michael MÜLLER, Michael HUBER, Dietrich KEPPLER, Gerhart KURZ

Journal:

Year:

1989

Language:

english

File:

PDF, 772 KB

english, 1989

57

Metabolism and actions of 2-deoxy-2-fluoro-d-galactose in vivo

Bernhard R. GRÜN, Ulrike BERGER, Franz OBERDORFER, William E. HULL, Hermann OSTERTAG, Eckhard FRIEDRICH, Jochen LEHMANN, Dietrich KEPPLER

Journal:

Year:

1990

Language:

english

File:

PDF, 971 KB

english, 1990

58

Metabolism of cysteinyl leukotrienes in monkey and man

Michael HUBER, Juliane MÜLLER, Inka LEIER, Gabriele JEDLITSCHKY, Howard A. BALL, Kevin P. MOORE, Graham W. TAYLOR, Roger WILLIAMS, Dietrich KEPPLER

Journal:

Year:

1990

Language:

english

File:

PDF, 752 KB

english, 1990

59

Halothane metabolism : Impairment of hepatic ω-oxidation of leukotrienes in vivo and in vitro

Jörg HUWYLER, Gabriele JEDLITSCHKY, Dietrich KEPPLER, Josef GUT

Journal:

Year:

1992

Language:

english

File:

PDF, 1.20 MB

english, 1992

60

Leukotriene uptake by hepatocytes and hepatoma cells

Inka LEIER, Michael MÜLLER, Gabriele JEDLITSCHKY, Dietrich KEPPLER

Journal:

Year:

1992

Language:

english

File:

PDF, 913 KB

english, 1992

61

Functional Reconstitution of ATP-Dependent Transporters from the Solubilized Hepatocyte Canalicular Membrane

Markus Büchler, Matthias Böhme, Helga Ortlepp, Dietrich Keppler

Journal:

Year:

1994

Language:

english

File:

PDF, 868 KB

english, 1994

62

Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells

Inka LEIER, Gabriele JEDLITSCHKY, Ulrike BUCHHOLZ, Dietrich KEPPLER

Journal:

Year:

1994

Language:

english

File:

PDF, 933 KB

english, 1994

63

Activation of Gene Transcription by Prostacyclin Analogues is Mediated by the Peroxisome-Proliferators-Activated Receptor (PPAR)

Rachel Hertz, Ina Berman, Dietrich Keppler, Jacob Bar-Tana

Journal:

Year:

1996

Language:

english

File:

PDF, 1.49 MB

english, 1996

64

Identification of the Multidrug-Resistance Protein (MRP) as the Glutathione-S-Conjugate Export Pump of Erythrocytes

Lukasz Pulaski, Gabriele Jedlitschky, Inka Leier, Ulrike Buchholz, Dietrich Keppler

Journal:

Year:

1996

Language:

english

File:

PDF, 603 KB

english, 1996

65

Identification of the Biosynthetic Leukotriene C4 Export Pump in Murine Mastocytoma Cells as a Homolog of the Multidrug-Resistance Protein

Inka Leier, Gabriele Jedlitschky, Markus Büchler, Ulrike Buchholz, Manuela Brom, Dietrich Keppler

Journal:

Year:

1996

Language:

english

File:

PDF, 619 KB

english, 1996

66

Inhibition of leukotriene ω-oxidation by ω-trifluoro analogs of leukotrienes

Gabriele Jedlitschky, Inka Leier, Michael Huber, Doris Mayer, Dietrich Keppler

Journal:

Archives of Biochemistry and Biophysics

Year:

1990

Language:

english

File:

PDF, 655 KB

english, 1990

67

Activity and distribution of the enzymes of uridylate synthesis from orotate in animal tissues

Jürgen Pausch, Dietrich Keppler, Karl Decker

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1972

Language:

english

File:

PDF, 494 KB

english, 1972

68

Inhibition of tyrosine aminotransferase induction by UTP deficiency and its reversal by 5-fluorouridine in cultured hepatoma cells

Eva M. Giesen, Gisèle Beck, Axel Holstege, Dietrich O.R. Keppler

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Year:

1981

Language:

english

File:

PDF, 537 KB

english, 1981

69

w-Oxidation products of leukotriene E4 in bile and urine of the monkey

Howard A. Ball, Dietrich Keppler

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 495 KB

english, 1987

70

Combined action of acivicin and d-galactosamine on pyrimidine nucleotide metabolism in hepatoma cells

Karen Leube, Dietrich O.R. Keppler

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 545 KB

english, 1983

71

Substrate properties of 5-fluorouridine diphospho sugars detected in hepatoma cells

Gisbert Weckbecker, Dietrich O.R. Keppler

Journal:

Biochemical Pharmacology

Year:

1984

Language:

english

File:

PDF, 728 KB

english, 1984

72

Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent atp-dependent transport across the canalicular membrane

Gabriele Jedlitschky, Inka Leier, Matthias Böhme, Ulrike Buchholz, Jacob Bar-Tana, Dietrich Keppler

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 993 KB

english, 1994

73

Increased activities of hepatic orotidine 5′-phosphate pyrophosphorylase and orotidine 5′-phosphate decarboxylase induced by orotate

Jürgen Pausch, Dietrich Keppler, Karl Decker

Journal:

Year:

1972

Language:

english

File:

PDF, 216 KB

english, 1972

74

Aspartate carbamoyltransferase inhibition and uridylate trapping result in a synergistic depression of uridine triphosphate in hepatoma cells

Dietrich O.R. Keppler

Journal:

Year:

1977

Language:

english

File:

PDF, 349 KB

english, 1977

75

Increased formation of nucleotide derivatives of 5-fluorouridine in hepatoma cells treated with inhibitors of pyrimidine synthesis and D-galactosamine

Axel Holstege, Brigitte Herrmann, Dietrich O.R. Keppler

Journal:

Year:

1978

Language:

english

File:

PDF, 473 KB

english, 1978

76

Depletion of cytidine triphosphate as a consequence of cellular uridine triphosphate deficiency

Hanspeter Henninger, Axel Holstege, Brigitte Herrmann, Tongtavuch Anukarahanonta, Dietrich O.R. Keppler

Journal:

Year:

1979

Language:

english

File:

PDF, 260 KB

english, 1979

77

Production of peptide leukotrienes in endotoxin shock

Wolfgang Hagmann, Claudio Denzlinger, Dietrich Keppler

Journal:

Year:

1985

Language:

english

File:

PDF, 487 KB

english, 1985

78

ATP-dependent leukotriene export from mastocytoma cells

Thomas Schaub, Toshihisa Ishikawa, Dietrich Keppler

Journal:

Year:

1991

Language:

english

File:

PDF, 561 KB

english, 1991

79

2-Deoxy-2-fluoro-D-galactose protein N-glycosylation

Nikolaus Loch, Christoph C. Geilen, Irmgard Spörndle, Franz Oberdorfer, Dietrich Keppler, Rudolf Tauber, Werner Reutter

Journal:

Year:

1991

Language:

english

File:

PDF, 452 KB

english, 1991

80

Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane

Matthias Böhme, Markus Büchler, Michael Müller, Dietrich Keppler

Journal:

Year:

1993

Language:

english

File:

PDF, 536 KB

english, 1993

81

ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein

Michael Müller, Rosmarie Mayer, Ulrike Hero, Dietrich Keppler

Journal:

Year:

1994

Language:

english

File:

PDF, 605 KB

english, 1994

82

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

Jörg König, Anne T. Nies, Yunhai Cui, Inka Leier, Dietrich Keppler

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1999

Language:

english

File:

PDF, 1.31 MB

english, 1999

83

The canalicular multidrug resistance protein, cMRP/MRP2, a novel conjugate export pump expressed in the apical membrane of hepatocytes

Dietrich Keppler, Jörg König, Markus Büchler

Journal:

Advances in Enzyme Regulation

Year:

1997

Language:

english

File:

PDF, 1.31 MB

english, 1997

84

Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family

Dietrich Keppler, Toshinori Kamisako, Inka Leier, Yunhai Cui, Anne T Nies, Hiroyuki Tsujii, Jörg König

Journal:

Advances in Enzyme Regulation

Year:

2000

Language:

english

File:

PDF, 358 KB

english, 2000

85

Export pumps for anionic conjugates encoded by MRP genes

Dietrich Keppler, Yunhai Cui, Jörg König, Inka Leier, Anne Nies

Journal:

Advances in Enzyme Regulation

Year:

1999

Language:

english

File:

PDF, 141 KB

english, 1999

86

Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis

Hideyuki Kojima, Anne T Nies, Jörg König, Wolfgang Hagmann, Herbert Spring, Masahito Uemura, Hiroshi Fukui, Dietrich Keppler

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 677 KB

english, 2003

87

Selective Guanosine Phosphate Deficiency in Hepatoma Cells Induced by Inhibitors of IMP Dehydrogenase

KAISER, Werner A., HERRMANN, Brigitte, KEPPLER, Dietrich O. R.

Journal:

Hoppe-Seyler's Zeitschrift für physiologische Chemie

Year:

1980

File:

PDF, 1.01 MB

1980

88

Uridylate-trapping sugar analogs in combination with inhibitors of uridylate synthesis de novo and 5-fluorouridine

Dietrich Keppler, Joachim Fauler, Thomas Gasser, Axel Holstege, Karen Leube, Christa Schulz-Holstege, Gisbert Weckbecker

Journal:

Advances in Enzyme Regulation

Year:

1985

Language:

english

File:

PDF, 943 KB

english, 1985

89

Potentation of antimetabolite action by uridylate trapping

Dietrich Keppler, Axel Hostege, Gisbert Wechbecker, Joachim Fauler, Thomas Gasser

Journal:

Advances in Enzyme Regulation

Year:

1985

Language:

english

File:

PDF, 593 KB

english, 1985

90

Leukotriene C4 metabolism by hepatoma cells and liver

Dietrich Keppler, Michael Huber, Gisbert Weckbecker, Wolfgang Hagmann, Claudio Denzlinger, Albrecht Guhlmann

Journal:

Advances in Enzyme Regulation

Year:

1987

Language:

english

File:

PDF, 657 KB

english, 1987

91

Metabolic inactivation of leukotrienes

Dietrich Keppler, Michael Huber, Thomas Baumert, Albrecht Guhlmann

Journal:

Advances in Enzyme Regulation

Year:

1989

Language:

english

File:

PDF, 627 KB

english, 1989

92

In vivo metabolism and UTP-depleting action of 2-deoxy-2-fluoro-d-galactose

Bernhard R. Grün, Ulrike Berger, Franz Oberdorfer, William E. Hull, Hermann Ostertag, Dietrich Keppler

Journal:

Advances in Enzyme Regulation

Year:

1990

Language:

english

File:

PDF, 353 KB

english, 1990

93

Transport and in vivo elimination of cysteinyl leukotrienes

Dietrich Keppler, Michael Müller, Cornelia Klünemann, Albrecht Guhlmann, Katja Krauss, Juliane Müller, Ulrike Berger, Inka Leier, Ertan Mayatepek

Journal:

Advances in Enzyme Regulation

Year:

1992

Language:

english

File:

PDF, 469 KB

english, 1992

94

ATP-dependent export pumps and their inhibition by cyclosporins

Matthias Böhme, Gabriele Jedlitschky, Inka Leier, Markus Büchler, Dietrich Keppler

Journal:

Advances in Enzyme Regulation

Year:

1994

Language:

english

File:

PDF, 517 KB

english, 1994

95

Peroxisomal leukotriene degradation: Biochemical and clinical implications

Gabriele Jedlitschky, Ertan Mayatepek, Dietrich Keppler

Journal:

Advances in Enzyme Regulation

Year:

1993

Language:

english

File:

PDF, 672 KB

english, 1993

96

Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin–Johnson syndrome

Hiroyuki Tsujii*, Jörg König*, Daniel Rost*, Birgit Stöckel*, Ulrich Leuschner‡, Dietrich Keppler*

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 450 KB

english, 1999

97

Identification of the major endogenous leukotriene metabolite in the bile of rats as N-acetyl leukotrience E4

Wolfgang Hagmann, Claudio Denzlinger, Stephan Rapp, Gisbert Weckbecker, Dietrich Keppler

Journal:

Year:

1986

Language:

english

File:

PDF, 667 KB

english, 1986

98

Enterohepatic circulation of N-acetyl-leukotriene E4

Albrecht Guhlmann, Wolfgang Hagmann, Dietrich Keppler

Journal:

Year:

1987

Language:

english

File:

PDF, 397 KB

english, 1987

99

Promoting drug discovery by collaborative innovation: a novel risk- and reward-sharing partnership between the German Cancer Research Center and Bayer HealthCare

Ruth Wellenreuther, Dietrich Keppler, Dominik Mumberg, Karl Ziegelbauer, Monika Lessl

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

100

Expression and localization of the multidrug resistance proteins MRP2 and MRP3 in human gallbladder epithelia

Daniel Rost, Jorg Konig, Gunter Weiss, Ernst Klar, Wolfgang Stremmel, Dietrich Keppler

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 190 KB

english, 2001

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