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51

Quantitative approaches to defining normal and aberrant protein homeostasis

Vendruscolo, Michele, Dobson, Christopher M.

Journal:

Faraday Discussions

Year:

2009

Language:

english

File:

PDF, 986 KB

english, 2009

52

Importance of Metastable States in the Free Energy Landscapes of Polypeptide Chains

Auer, Stefan, Miller, Mark A., Krivov, Sergei V., Dobson, Christopher M., Karplus, Martin, Vendruscolo, Michele

Journal:

Physical Review Letters

Year:

2007

Language:

english

File:

PDF, 433 KB

english, 2007

53

Frequency Factors in a Landscape Model of Filamentous Protein Aggregation

Buell, Alexander K., Blundell, Jamie R., Dobson, Christopher M., Welland, Mark E., Terentjev, Eugene M., Knowles, Tuomas P. J.

Journal:

Physical Review Letters

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

54

A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma

Cohen, E Suzanne, Dobson, Claire L, Käck, Helena, Wang, Bing, Sims, Dorothy A, Lloyd, Christopher O, England, Elizabeth, Rees, D Gareth, Guo, Hongwei, Karagiannis, Sophia N, O’Brien, Siobhan, Persdott

Journal:

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

55

The amyloid state and its association with protein misfolding diseases

Knowles, Tuomas P. J., Vendruscolo, Michele, Dobson, Christopher M.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2014

File:

PDF, 516 KB

2014

56

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, Dirk M., Kasturi, Prasad, Zheng, Min, Pinkert, Stefan, Vecchi, Giulia, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele, Mann, Matthias, Hartl, F. Ulrich

Journal:

Year:

2015

Language:

english

File:

PDF, 3.04 MB

english, 2015

57

Protein Aggregation and Its Consequences for Human Disease

Dobson, Christopher

Journal:

Protein & Peptide Letters

Year:

2006

Language:

english

File:

PDF, 175 KB

english, 2006

58

Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity

Yates, Emma V., Müller, Thomas, Rajah, Luke, De Genst, Erwin J., Arosio, Paolo, Linse, Sara, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

Nature Chemistry

Year:

2015

Language:

english

File:

PDF, 2.65 MB

english, 2015

59

Structural effects of two camelid nanobodies directed to distinct C-terminal epitopes on α-synuclein

El-Turk, Farah, Newby, Francisco, de Genst, Erwin J., Guilliams, Tim, Sprules, Tara, Mittermaier, Anthony K., Dobson, Christopher M., Vendruscolo, Michele

Journal:

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

60

Prior Eccentric Exercise Reduces V[Combining Dot Above]O2peak and Ventilatory Threshold but Does Not Alter Movement Economy During Cycling Exercise

Black, Christopher D., Dobson, Richard M.

Journal:

The Journal of Strength and Conditioning Research

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

61

Physical determinants of the self-replication of protein fibrils

Šarić, Anđela, Buell, Alexander K., Meisl, Georg, Michaels, Thomas C. T., Dobson, Christopher M., Linse, Sara, Knowles, Tuomas P. J., Frenkel, Daan

Journal:

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

62

Hamiltonian Dynamics of Protein Filament Formation

Michaels, Thomas C. T., Cohen, Samuel I. A., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

Physical Review Letters

Year:

2016

Language:

english

File:

PDF, 672 KB

english, 2016

63

Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation

Zhang, Yingbo, Buell, Alexander K., Müller, Thomas, De Genst, Erwin, Benesch, Justin, Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.68 MB

english, 2016

64

Flowing fluid electrical conductivity logging of a deep borehole during and following drilling: estimation of transmissivity, water salinity and hydraulic head of conductive zones

Doughty, Christine, Tsang, Chin-Fu, Rosberg, Jan-Erik, Juhlin, Christopher, Dobson, Patrick F., Birkholzer, Jens T.

Journal:

Hydrogeology Journal

Year:

2017

Language:

english

File:

PDF, 3.31 MB

english, 2017

65

The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

Buell, Alexander K., Dobson, Christopher M., Knowles, Tuomas P.J.

Journal:

Essays in Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

66

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, Dirk M., Kasturi, Prasad, Zheng, Min, Pinkert, Stefan, Vecchi, Giulia, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele, Mann, Matthias, Hartl, F. Ulrich

Journal:

Year:

2017

Language:

english

File:

PDF, 61 KB

english, 2017

67

Identification Of Unpaved Roads in a Regional Road Network Using Remote Sensing

Brooks, ColinN., Dean, DavidB., Dobson, RichardJ., Roussi, Christopher, Carter, JustinF., VanderWoude, AndreaJ., Colling, Tim, Banach, DavidM.

Journal:

Photogrammetric Engineering & Remote Sensing

Year:

2017

Language:

english

File:

PDF, 1017 KB

english, 2017

68

Optical structural analysis of individual α-synuclein oligomers

Varela, Juan Alberto, Rodrigues, Margarida, De, Suman, Flagmeier, Patrick, Gandhi, Sonia, Dobson, Christopher M., Klenerman, David, Lee, Steven

Journal:

Angewandte Chemie International Edition

Year:

2018

Language:

english

File:

PDF, 4.86 MB

english, 2018

69

Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species

Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Ghandi, Sonia, Bohndiek, Sarah E., Snaddon,

Journal:

Royal Society Open Science

Year:

2018

Language:

english

File:

PDF, 954 KB

english, 2018

70

Microfluidic approaches for probing amyloid assembly and behaviour

Herling, Therese W., Levin, Aviad, Saar, Kadi L., Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

Year:

2018

Language:

english

File:

PDF, 8.91 MB

english, 2018

71

Fast Fluorescence Lifetime Imaging for Longitudinal Studies of Protein Aggregation in Living C. Elegans

Sinnige, Tessa, Laine, Romain F., Yu Ma, Kai, Haack, Amanda J., Gaida, Peter, Curry, Nathan, Perni, Michele, Nollen, Ellen A.A., Dobson, Christopher M., Vendruscolo, Michele, Kaminski Schierle, Gabrie

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 46 KB

english, 2018

72

Correction to ‘Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species’

Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Gandhi, Sonia, Bohndiek, Sarah E., Snaddon,

Journal:

Royal Society Open Science

Year:

2018

Language:

english

File:

PDF, 413 KB

english, 2018

73

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

Pickhardt, Marcus, Neumann, Thomas, Schwizer, Daniel, Callaway, Kari, Vendruscolo, Michele, Schenk, Dale, George-Hyslop, Peter, Mandelkow, Eva, Dobson, Christopher, McConlogue, Lisa, Mandelkow, Eckhar

Journal:

Current Alzheimer Research

Year:

2015

Language:

english

File:

PDF, 11.23 MB

english, 2015

74

Statistical Mechanics of Globular Oligomer Formation by Protein Molecules

Dear, Alexander John, Saric, Andela, Michaels, Thomas C.T., Dobson, Christopher M., Knowles, Tuomas P.J.

Journal:

Journal of Physical Chemistry B

Year:

2018

Language:

english

File:

PDF, 716 KB

english, 2018

75

C9orf72 intermediate expansions of 24–30 repeats are associated with ALS

Iacoangeli, Alfredo, Al Khleifat, Ahmad, Jones, Ashley R., Sproviero, William, Shatunov, Aleksey, Opie-Martin, Sarah, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Fogh, Isabella, Dobson,

Journal:

Acta Neuropathologica Communications

Year:

2019

Language:

english

File:

PDF, 666 KB

english, 2019

76

Analgesic Benefit of Pectoral Nerve Block II Blockade for Open Subpectoral Biceps Tenodesis

Reynolds, J. Wells, Henshaw, Daryl S., Jaffe, J. Douglas, Dobson, Sean W., Edwards, Christopher J., Turner, James D., Weller, Robert S., Graves, Benjamin R., Freehill, Michael T.

Journal:

Anesthesia & Analgesia

Year:

2019

Language:

english

File:

PDF, 438 KB

english, 2019

77

Covalent Adaptable Networks: Toward StimuliâResponsive Dynamic Thermosets through Continuous Development and Improvements in Covalent Adaptable Networks (CANs) (Adv. Mater. 20/2020)

PodgÃ³rski, Maciej, Fairbanks, Benjamin D., Kirkpatrick, Bruce E., McBride, Matthew, Martinez, Alina, Dobson, Adam, Bongiardina, Nicholas J., Bowman, Christopher N.

Journal:

Advanced Materials

Year:

2020

File:

PDF, 1.70 MB

2020

78

Ecological Synthesis and Its Role in Advancing Knowledge

Halpern, Benjamin S, Berlow, Eric, Williams, Rich, Borer, Elizabeth T, Davis, Frank W, Dobson, Andy, Enquist, Brian J, Froehlich, Halley E, Gerber, Leah R, Lortie, Christopher J, O'connor, Mary I, Reg

Journal:

Year:

2020

File:

PDF, 1.97 MB

2020

79

Multi-wavelength analytical ultracentrifugation as a tool to characterise proteinâDNA interactions in solution

Horne, Christopher R., Henrickson, Amy, Demeler, Borries, Dobson, Renwick C. J.

Journal:

European Biophysics Journal

Year:

2020

File:

PDF, 1.87 MB

2020

80

Molecular dynamics simulations of human α-lactalbumin: Changes to the structural and dynamical properties of the protein at low pH

Lorna J. Smith, Christopher M. Dobson, Wilfred F. van Gunsteren

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

81

NMR and protein dynamics

Lorna J. Smith, Christopher M. Dobson

Journal:

International Journal of Quantum Chemistry

Year:

1996

Language:

english

File:

PDF, 1.43 MB

english, 1996

82

Proteinfaltung aus theoretischer und experimenteller Sicht

Christopher M. Dobson, Andrej Šali, Martin Karplus

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 1.03 MB

german, 1998

83

Orange Electroluminescence from a Divalent Europium Complex

Christopher P. Shipley, Simone Capecchi, Oleg V. Salata, Mark Etchells, Peter J. Dobson, Victor Christou

Journal:

Advanced Materials

Year:

1999

Language:

english

File:

PDF, 158 KB

english, 1999

84

Differential gene regulation by 9-cis and all-trans retinoic acid in neuroblastoma cells

P.E. Lovat, M. Dobson, A.J. Malcolm, A.D.J. Pearson, Christopher P.F. Redfern

Journal:

Pediatric Blood & Cancer

Year:

2001

Language:

english

File:

PDF, 244 KB

english, 2001

85

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Using Drosophila to Reveal Insight into Protein Misfolding Diseases

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 2.32 MB

english, 2010

86

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Why Proteins Misfold

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 532 KB

english, 2010

87

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Hemodialysis-Related Amyloidosis

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 3.28 MB

english, 2010

88

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Systemic Amyloidoses

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

89

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Misfolding and Aggregation in Huntington Disease and Other Expanded Polyglutamine Repeat Diseases

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 379 KB

english, 2010

90

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Prion Disease Therapy: Trials and Tribulations

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 414 KB

english, 2010

91

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Thiopurine S-Methyltransferase Pharmacogenomics: Protein Misfolding, Aggregation, and Degradation

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 739 KB

english, 2010

92

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Alzheimer Disease: Protein Misfolding, Model Systems, and Experimental Therapeutics

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

93

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Gaucher Disease

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

94

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Animal Models to Study the Biology of Amyloid-β Protein Misfolding in Alzheimer Disease

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 4.62 MB

english, 2010

95

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Endoplasmic Reticulum Stress and Oxidative Stress: Mechanisms and Link to Disease

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 517 KB

english, 2010

96

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Folding Biology of Cystic Fibrosis: A Consortium-Based Approach to Disease

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 298 KB

english, 2010

97

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Copper-Zinc Superoxide Dismutase, Its Copper Chaperone, and Familial Amyotrophic Lateral Sclerosis

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 2.53 MB

english, 2010

98

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Alpha-1-Antitrypsin Deficiency

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

99

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Imaging of Misfolded Proteins

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 480 KB

english, 2010

100

Protein Misfolding Diseases (Current and Emerging Principles and Therapies) || Aging and Aggregation-Mediated Proteotoxicity

Ramirez-Alvarado, Marina, Kelly, Jeffery W., Dobson, Christopher M.

Year:

2010

Language:

english

File:

PDF, 382 KB

english, 2010