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51

From CLL to Multiple Myeloma - Spleen Tyrosine Kinase (SYK) influences multiple myeloma cell survival and migration

Lorenz, Joschka, Waldschmidt, Johannes, Wider, Dagmar, Follo, Marie, Ihorst, Gabriele, Chatterjee, Manik, May, Annette M., Duyster, Justus, Rosenwald, Andreas, Wäsch, Ralph, Zirlik, Katja, Engelhardt,

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 426 KB

english, 2015

52

Anti-thymocyte globulin-induced hyperbilirubinemia in patients with myelofibrosis undergoing allogeneic hematopoietic cell transplantation

Ecsedi, Matyas, Schmohl, Jörg, Zeiser, Robert, Drexler, Beatrice, Halter, Jörg, Medinger, Michael, Duyster, Justus, Kanz, Lothar, Passweg, Jakob, Finke, Jürgen, Bethge, Wolfgang, Lengerke, Claudia

Journal:

Annals of Hematology

Year:

2016

Language:

english

File:

PDF, 402 KB

english, 2016

53

Das Blaue Buch || Kopf-Hals Tumoren

Engelhardt, Monika, Berger, Dietmar P., Mertelsmann, Roland, Duyster, Justus

Year:

2017

Language:

german

File:

PDF, 3.63 MB

german, 2017

54

Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy

Hiller, Jan K., Schmoor, Claudia, Gaidzik, Verena I., Schmidt-Salzmann, Charlotte, Yalcin, Arzu, Abdelkarim, Mahmoud, Blagitko-Dorfs, Nadja, Döhner, Konstanze, Bullinger, Lars, Duyster, Justus, Lübber

Journal:

Annals of Hematology

Year:

2017

Language:

english

File:

PDF, 451 KB

english, 2017

55

Successful peripheral blood stem cell mobilization with a cost-efficient single fixed-dose plerixafor schedule in poor mobilizers

Greil, Christine, Kiote-Schmidt, Chrissoula, Fink, Geertje, Ihorst, Gabriele, Hildenbeutel, Steffi, Bosse, Roland, Duyster, Justus, Engelhardt, Monika, Wäsch, Ralph

Journal:

Leukemia and Lymphoma

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

56

Early mixed hematopoietic chimerism detection by digital droplet PCR in patients undergoing gender-mismatched hematopoietic stem cell transplantation

Waterhouse, Miguel, Pfeifer, Dietmar, Follo, Marie, Duyster, Justus, Schäfer, Henning, Bertz, Hartmut, Finke, Jürgen

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2017

Language:

english

File:

PDF, 428 KB

english, 2017

57

Computational analysis of ABL kinase mutations allows predicting drug sensitivity against selective kinase inhibitors

Kamasani, Swapna, Akula, Sravani, Sivan, Sree Kanth, Manga, Vijjulatha, Duyster, Justus, Vudem, Dashavantha Reddy, Kancha, Rama Krishna

Journal:

Year:

2017

Language:

english

File:

PDF, 1.22 MB

english, 2017

58

FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin dependent kinase inhibitor p27Kip1 in acute myeloid leukemia

Peschel, Ines, Podmirseg, Silvio R., Taschler, Martin, Duyster, Justus, Götze, Katharina S., Sill, Heinz, Nachbaur, David, Jäkel, Heidelinde, Hengst, Ludger

Journal:

Year:

2017

Language:

english

File:

PDF, 3.45 MB

english, 2017

59

Paving the Way for Dose Banding of Chemotherapy: An Analytical Approach

Reinhardt, Heike, Trittler, Rainer, Eggleton, Alison G., Wöhrl, Stefan, Epting, Thomas, Buck, Marion, Kaiser, Sabine, Jonas, Daniel, Duyster, Justus, Jung, Manfred, Hug, Martin J., Engelhardt, Monika

Journal:

Journal of the National Comprehensive Cancer Network

Year:

2017

Language:

english

File:

PDF, 421 KB

english, 2017

60

Favourable outcomes of poor prognosis diffuse large B-cell lymphoma patients treated with dose-dense Rituximab, high-dose Methotrexate and six cycles of CHOP-14 compared to first-line autologous transplantation

Strüßmann, Tim, Fritsch, Kristina, Baumgarten, Axel, Fietz, Thomas, Engelhardt, Monika, Mertelsmann, Roland, Ihorst, Gabriele, Duyster, Justus, Finke, Jürgen, Marks, Reinhard

Journal:

British Journal of Haematology

Year:

2017

Language:

english

File:

PDF, 290 KB

english, 2017

61

CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma

Waldschmidt, Johannes M., Simon, Anna, Wider, Dagmar, Müller, Stefan J., Follo, Marie, Ihorst, Gabriele, Decker, Sarah, Lorenz, Joschka, Chatterjee, Manik, Azab, Abdel K., Duyster, Justus, Wäsch, Ralp

Journal:

British Journal of Haematology

Year:

2017

Language:

english

File:

PDF, 989 KB

english, 2017

62

Stem cell mobilization in poor mobilizers with multiple myeloma or lymphoma before and after introduction of plerixafor: a single-center comparative analysis using a cost-efficient single fixed-dose schedule

Greil, Christine, Ihorst, Gabriele, Kiote-Schmidt, Chrissoula, Hildenbeutel, Steffi, Kühbach, Katja, Bosse, Roland, Duyster, Justus, Engelhardt, Monika, Wäsch, Ralph

Journal:

Leukemia and Lymphoma

Year:

2017

Language:

english

File:

PDF, 733 KB

english, 2017

63

Cell-free DNA characteristics and chimerism analysis in patients after allogeneic cell transplantation

Duque-Afonso, Jesus, Waterhouse, Miguel, Pfeifer, Dietmar, Follo, Marie, Duyster, Justus, Bertz, Hartmut, Finke, Jürgen

Journal:

Clinical Biochemistry

Year:

2017

Language:

english

File:

PDF, 396 KB

english, 2017

64

Differential Sensitivity of ERBB2 Kinase Domain Mutations towards Lapatinib

Kancha, Rama Krishna, von Bubnoff, Nikolas, Bartosch, Natalie, Peschel, Christian, Engh, Richard A., Duyster, Justus, Ouchi, Toru

Journal:

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

65

Analysis of Conformational Determinants Underlying HSP90-Kinase Interaction

Kancha, Rama Krishna, Bartosch, Natalie, Duyster, Justus, Picard, Didier

Journal:

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

66

Inhibition of Aurora Kinase B Is Important for Biologic Activity of the Dual Inhibitors of BCR-ABL and Aurora Kinases R763/AS703569 and PHA-739358 in BCR-ABL Transformed Cells

Illert, Anna L., Seitz, Anna K., Rummelt, Christoph, Kreutmair, Stefanie, Engh, Richard A., Goodstal, Samantha, Peschel, Christian, Duyster, Justus, von Bubnoff, Nikolas, Prigent, Claude

Journal:

Year:

2014

Language:

english

File:

PDF, 3.99 MB

english, 2014

67

Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing

Riba, Julian, Renz, Nathalie, Niemöller, Christoph, Bleul, Sabine, Pfeifer, Dietmar, Stosch, Juliane M., Metzeler, Klaus H., Hackanson, Björn, Lübbert, Michael, Duyster, Justus, Koltay, Peter, Zengerl

Journal:

Year:

2016

Language:

english

File:

PDF, 2.88 MB

english, 2016

68

Decitabine in Combination with Donor Lymphocyte Infusions can Induce Remissions in relapsed Myeloid Malignancies with Higher Leukemic Burden after Allogeneic Hematopoietic Cell Transplantation

Sommer, Sebastian, Cruijsen, Marjan, Claus, Rainer, Bertz, Hartmut, Wäsch, Ralph, Marks, Reinhard, Zeiser, Robert, Bogatyreva, Lioudmila, Blijlevens, Nicole M.A., May, Annette, Duyster, Justus, Huls,

Journal:

Leukemia Research

Year:

2018

Language:

english

File:

PDF, 347 KB

english, 2018

69

Current Immunotherapeutic Approaches in T Cell Non-Hodgkin Lymphomas

Poggio, Teresa, Duyster, Justus, Illert, Anna

Journal:

Year:

2018

Language:

english

File:

PDF, 268 KB

english, 2018

70

Allogeneic transplantation of multiple myeloma patients may allow long-term survival in carefully selected patients with acceptable toxicity and preserved quality of life

Greil, Christine, Engelhardt, Monika, Ihorst, Gabriele, Schoeller, Katja, Bertz, Hartmut, Marks, Reinhard, Zeiser, Robert, Duyster, Justus, Einsele, Hermann, Finke, Jürgen, Wäsch, Ralph

Journal:

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

71

APC/CCdh1 regulates the balance between maintenance and differentiation of hematopoietic stem and progenitor cells

Ewerth, Daniel, Kreutmair, Stefanie, Schmidts, Andrea, Ihorst, Gabriele, Follo, Marie, Wider, Dagmar, Felthaus, Julia, Schüler, Julia, Duyster, Justus, Illert, Anna Lena, Engelhardt, Monika, Wäsch, Ra

Journal:

Cellular and Molecular Life Sciences

Year:

2018

Language:

english

File:

PDF, 5.98 MB

english, 2018

72

Ruxolitinib in GvHD (RIG) study: a multicenter, randomized phase 2 trial to determine the response rate of Ruxolitinib and best available treatment (BAT) versus BAT in steroid-refractory acute graft-versus-host disease (aGvHD) (NCT02396628)

von Bubnoff, Nikolas, Ihorst, Gabriele, Grishina, Olga, Röthling, Nadine, Bertz, Hartmut, Duyster, Justus, Finke, Jürgen, Zeiser, Robert

Journal:

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

73

Droplet digital PCR for the simultaneous analysis of minimal residual disease and hematopoietic chimerism after allogeneic cell transplantation

Waterhouse, Miguel, Pfeifer, Dietmar, Duque-Afonso, Jesus, Follo, Marie, Duyster, Justus, Depner, Melanie, Bertz, Hartmut, Finke, Jürgen

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2018

Language:

english

File:

PDF, 388 KB

english, 2018

74

Biology-driven approaches to prevent and treat relapse of myeloid neoplasia after allogeneic hematopoietic stem cell transplantation

Zeiser, Robert, Beelen, Dietrich W., Bethge, Wolfgang, Bornhäuser, Martin, Bug, Gesine, Burchert, Andreas, Christopeit, Maximilian, Duyster, Justus, Finke, Jürgen, Gerbitz, Armin, Klusmann, Jan Hennin

Journal:

Biology of Blood and Marrow Transplantation

Year:

2019

Language:

english

File:

PDF, 710 KB

english, 2019

75

Avoiding chemotherapy prescribing errors: Analysis and innovative strategies

Reinhardt, Heike, Otte, Petra, Eggleton, Alison G., Ruch, Markus, Wöhrl, Stefan, Ajayi, Stefanie, Duyster, Justus, Jung, Manfred, Hug, Martin J., Engelhardt, Monika

Journal:

Year:

2019

Language:

english

File:

PDF, 481 KB

english, 2019

76

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia

Becker, Heiko, Greve, Gabriele, Kataoka, Keisuke, Mallm, Jan-Philipp, Duque-Afonso, Jesús, Ma, Tobias, Niemöller, Christoph, Pantic, Milena, Duyster, Justus, Cleary, Michael L., Schüler, Julia, Rippe,

Journal:

Year:

2019

Language:

english

File:

PDF, 989 KB

english, 2019

77

Clonal hematopoiesis of indeterminate potential in older patients having received an allogeneic stem cell transplantation from young donors

Heumüller, Anezka, Wehrle, Julius, Stosch, Juliane, Niemöller, Christoph, Bleul, Sabine, Waterhouse, Miguel, Uhl, David, Metzeler, Klaus H., Lübbert, Michael, Duyster, Justus, Finke, Jürgen, Becker, H

Journal:

Bone Marrow Transplantation

Year:

2019

Language:

english

File:

PDF, 434 KB

english, 2019

78

Phenotypical and functional analysis of donor lymphocyte infusion products after long-term cryopreservation

Schäfer, Ann-Kathrin, Waterhouse, Miguel, Follo, Marie, Duque-Afonso, Jesus, Duyster, Justus, Bertz, Hartmut, Finke, Jürgen

Journal:

Transfusion and Apheresis Science

Year:

2019

Language:

english

File:

PDF, 457 KB

english, 2019

79

TP53 abnormalities and chromosomal aneuploidy in acute panmyelosis with myelofibrosis

Pantic, Milena, Pfeifer, Dietmar, Kapp-Schwoerer, Silke, Ihorst, Gabriele, Becker, Heiko, Zeiser, Robert, Duyster, Justus, Schmitt-Graeff, Annette

Journal:

Year:

2019

File:

PDF, 1.05 MB

2019

80

Time from first symptom onset to the final diagnosis of multiple myeloma (MM) – possible risks and future solutions: retrospective and prospective ‘Deutsche Studiengruppe MM’ (DSMM) and ‘European Myeloma Network’ (EMN) analysis

Graziani, Giulia, Herget, Georg W., Ihorst, Gabriele, Zeissig, Mara, Chaidos, Aristeidis, Auner, Holger W., Duyster, Justus, Wäsch, Ralph, Engelhardt, Monika

Journal:

Leukemia and Lymphoma

Year:

2019

Language:

english

File:

PDF, 1.52 MB

english, 2019

81

Venetoclax in combination with carfilzomib, doxorubicin and dexamethasone restores responsiveness in an otherwise treatment-refractory multiple myeloma patient

Bojtine Kovacs, Sarolta, Luan, Jingting, Dold, Sandra Maria, Weis, Andreas, Pantic, Milena, Duyster, Justus, Wäsch, Ralph, Engelhardt, Monika

Journal:

Year:

2019

Language:

english

File:

PDF, 388 KB

english, 2019

82

Venetoclax in combination with carfilzomib, doxorubicin and dexamethasone restores responsiveness in an otherwise treatment-refractory multiple myeloma patient

Bojtine Kovacs, Sarolta, Luan, Jingting, Dold, Sandra Maria, Weis, Andreas, Pantic, Milena, Duyster, Justus, Wäsch, Ralph, Engelhardt, Monika

Journal:

Year:

2019

File:

PDF, 388 KB

2019

83

CCL5 mediates target‐kinase independent resistance to FLT3 inhibitors in FLT3‐ITD‐positive AML

Waldeck, Silvia, Rassner, Michael, Keye, Philip, Follo, Marie, Herchenbach, Dieter, Endres, Cornelia, Charlet, Anne, Andrieux, Geoffroy, Salzer, Ulrich, Boerries, Melanie, Duyster, Justus, von Bubnoff

Journal:

Molecular Oncology

Year:

2020

Language:

english

File:

PDF, 1.77 MB

english, 2020

84

Nucleophosminâanaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway

Bai, Ren-Yuan, Ouyang, Tao, Miething, Cornelius, Morris, Stephan W., Peschel, Christian, Duyster, Justus

Journal:

Year:

2000

Language:

english

File:

PDF, 364 KB

english, 2000

85

Characterization of Grb4, an adapter protein interacting with Bcr-Abl

Coutinho, Sunita, Jahn, Thomas, Lewitzky, Marc, Feller, Stephan, Hutzler, Peter, Peschel, Christian, Duyster, Justus

Journal:

Year:

2000

File:

PDF, 218 KB

2000

86

Bcr-Abl kinase down-regulates cyclin-dependent kinase inhibitor p27 in human and murine cell lines

Jonuleit, Tarja, van der Kuip, Heiko, Miething, Cornelius, Michels, Heike, Hallek, Michael, Duyster, Justus, Aulitzky, Walter E.

Journal:

Year:

2000

File:

PDF, 263 KB

2000

87

Development and clinical validation of discriminatory multi-target digital droplet PCR assays for the detection of hot spot KRAS and NRAS mutations in cell-free DNA

Hussung, Saskia, Follo, Marie, Klar, Rhena F.U., Michalczyk, Sandra, Fritsch, Kornelia, Nollmann, Friederike, Hipp, Julian, Duyster, Justus, Scherer, Florian, von Bubnoff, Nikolas, Boerries, Melanie,

Journal:

The Journal of Molecular Diagnostics

Year:

2020

File:

PDF, 6.12 MB

2020

88

Risk of disease recurrence and survival in patients with multiple myeloma: A German study group analysis using a conditional survival approach with longâterm followâup of 815 patients

Schinke, Maximilian, Ihorst, Gabriele, Duyster, Justus, WÃ¤sch, Ralph, Schumacher, Martin, Engelhardt, Monika

Journal:

Year:

2020

File:

PDF, 795 KB

2020

89

Ibrutinib in patients with relapsed/refractory central nervous system lymphoma: A retrospective singleâcentre analysis

Lauer, Eliza M., Waterhouse, Miguel, Braig, Moritz, Mutter, Jurik, Bleul, Sabine, DuqueâAfonso, JesÃºs, Duyster, Justus, Marks, Reinhard, Reinacher, Peter C., Prinz, Marco, Illerhaus, Gerald, Finke,

Journal:

British Journal of Haematology

Year:

2020

File:

PDF, 202 KB

2020

90

Circulating Tumor DNA Allows Early Treatment Monitoring in BRAF- and NRAS-Mutant Malignant Melanoma

Braune, Jan, Keller, Laura, Schiller, Florian, Graf, Erika, Rafei-Shamsabadi, David, Wehrle, Julius, Follo, Marie, Philipp, Ulrike, Hussung, Saskia, Pfeifer, Dietmar, Mix, Michael, Duyster, Justus, Fr

Journal:

JCO Precision Oncology

Year:

2020

File:

PDF, 817 KB

2020

91

Prevalence and characteristics of myeloproliferative neoplasms with concomitant monoclonal gammopathy

Javorniczky, Nora Rebeka, Wehrle, Julius, Ihorst, Gabriele, Hupfer, Valerie, Aumann, Konrad, Pfeifer, Dietmar, NiemÃ¶ller, Christoph, Bleul, Sabine, Pantic, Milena, Werner, Martin, Duyster, Justus, Fi

Journal:

Leukemia Research

Year:

2020

File:

PDF, 1.21 MB

2020

92

Colon and liver tissue damage detection using methylated SESN3 and PTK2B genes in circulating cell-free DNA in patients with acute graft-versus-host disease

Waterhouse, Miguel, Pennisi, Sandra, Pfeifer, Dietmar, Deuter, Max, von Bubnoff, Nikolas, Scherer, Florian, StrÃ¼ssmann, Tim, Wehr, Claudia, Duyster, Justus, Bertz, Hartmut, Finke, JÃ¼rgen, Duque-Afon

Journal:

Bone Marrow Transplantation

Year:

2020

File:

PDF, 787 KB

2020

93

Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo

Rummelt, Christoph, Gorantla, Sivahari P., Meggendorfer, Manja, Charlet, Anne, Endres, Cornelia, DÃ¶hner, Konstanze, Heidel, Florian H., Fischer, Thomas, Haferlach, Torsten, Duyster, Justus, von Bubno

Journal:

Year:

2020

File:

PDF, 1.58 MB

2020

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