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1

Nitroimidazole Action in Entamoeba histolytica: A Central Role for Thioredoxin Reductase

Leitsch, David, Kolarich, Daniel, Wilson, Iain B. H., Altmann, Friedrich, Duchêne, Michael

Journal:

Year:

2007

Language:

english

File:

PDF, 559 KB

english, 2007

2

A review on metronidazole: an old warhorse in antimicrobial chemotherapy

Journal:

Year:

2017

Language:

english

File:

PDF, 391 KB

english, 2017

3

Acanthamoebastrains lose their abilities to encyst synchronously upon prolonged axenic culture

Martina Köhsler, David Leitsch, Ursula Fürnkranz, Michael Duchêne, Horst Aspöck, Julia Walochnik

Journal:

Parasitology Research

Year:

2008

Language:

english

File:

PDF, 92 KB

english, 2008

4

Comparison of the proteome profiles ofEntamoeba histolyticaand its close but non-pathogenic relativeEntamoeba dispar

David Leitsch, Iain B. Wilson, Katharina Paschinger, Michael Duchêne

Journal:

Wiener klinische Wochenschrift

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

5

Development of a pharmacodynamic screening model withEntamoeba histolytica

Oumaporn Tasanor, Brigitte Brem, David Leitsch, Marina Binder, Michael Duchêne, Harald Greger, Walther H. Wernsdorfer

Journal:

Wiener klinische Wochenschrift

Year:

2007

File:

PDF, 391 KB

2007

6

Researcher of the month

Journal:

Wiener klinische Wochenschrift

Year:

2010

Language:

german

File:

PDF, 137 KB

german, 2010

7

Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance

David Leitsch, Daniel Kolarich, Marina Binder, Johannes Stadlmann, Friedrich Altmann, Michael Duchêne

Journal:

Molecular Microbiology

Year:

2009

Language:

english

File:

PDF, 587 KB

english, 2009

8

Acanthamoeba castellanii : growth on human cell layers reactivates attenuated properties after prolonged axenic culture

Martina Koehsler, David Leitsch, Michael Duchêne, Markus Nagl, Julia Walochnik

Journal:

FEMS Microbiology Letters

Year:

2009

Language:

english

File:

PDF, 158 KB

english, 2009

9

Proteomic aspects of Parachlamydia acanthamoebae infection in Acanthamoeba spp.

Leitsch, David, Köhsler, Martina, Marchetti-Deschmann, Martina, Deutsch, Andrea, Allmaier, Günter, König, Lena, Sixt, Barbara S, Duchêne, Michael, Walochnik, Julia

Journal:

The ISME Journal

Year:

2010

Language:

english

File:

PDF, 561 KB

english, 2010

10

RNA chaperone activity of the Sm-like Hfq protein

Moll, Isabella, Leitsch, David, Steinhauser, Tanja, Bläsi, Udo

Journal:

Year:

2003

Language:

english

File:

PDF, 427 KB

english, 2003

11

Entamoeba histolytica: Analysis of the trophozoite proteome by two-dimensional polyacrylamide gel electrophoresis

David Leitsch, Christian Radauer, Katharina Paschinger, Iain B.H. Wilson, Heimo Breiteneder, Otto Scheiner, Michael Duchêne

Journal:

Experimental Parasitology

Year:

2005

Language:

english

File:

PDF, 410 KB

english, 2005

12

Entamoeba histolytica: Response of the parasite to metronidazole challenge on the levels of mRNA and protein expression

Margit Tazreiter, David Leitsch, Evelyn Hatzenbichler, Georg E. Mair-Scorpio, Ralf Steinborn, Martin Schreiber, Michael Duchêne

Journal:

Experimental Parasitology

Year:

2008

Language:

english

File:

PDF, 281 KB

english, 2008

13

The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways

David Leitsch, Daniel Kolarich, Michael Duchêne

Journal:

Molecular and Biochemical Parasitology

Year:

2010

Language:

english

File:

PDF, 614 KB

english, 2010

14

Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis

David Leitsch, Mirjana Drinić, Daniel Kolarich, Michael Duchêne

Journal:

Molecular and Biochemical Parasitology

Year:

2012

Language:

english

File:

PDF, 425 KB

english, 2012

15

Tritrichomonas foetus isolates from cats and cattle show minor genetic differences in unrelated loci ITS-2 and EF-1α

Karin Reinmann, Norbert Müller, Peter Kuhnert, Carlos M. Campero, David Leitsch, Michael Hess, Klaus Henning, Marcelo Fort, Joachim Müller, Bruno Gottstein, Caroline F. Frey

Journal:

Veterinary Parasitology

Year:

2012

Language:

english

File:

PDF, 1.95 MB

english, 2012

16

Nitroimidazole drugs vary in their mode of action in the human parasite Giardia lamblia

David Leitsch, Sarah Schlosser, Anita Burgess, Michael Duchêne

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2012

Language:

english

File:

PDF, 313 KB

english, 2012

17

Entamoeba histolytica : identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example

Schlosser, Sarah, Leitsch, David, Duchêne, Michael

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 822 KB

english, 2013

18

Geometric curvature controls the chemical patchiness and self-assembly of nanoparticles

Walker, David A., Leitsch, Emily K., Nap, Rikkert J., Szleifer, Igal, Grzybowski, Bartosz A.

Journal:

Nature Nanotechnology

Year:

2013

Language:

english

File:

PDF, 3.46 MB

english, 2013

19

Trichomonas vaginalis flavin reductase 1 and its role in metronidazole resistance

Leitsch, David, Janssen, Brian D., Kolarich, Daniel, Johnson, Patricia J., Duchêne, Michael

Journal:

Molecular Microbiology

Year:

2014

Language:

english

File:

PDF, 2.14 MB

english, 2014

20

Unexpected properties of NADP-dependent secondary alcohol dehydrogenase (ADH-1) in Trichomonas vaginalis and other microaerophilic parasites

Leitsch, David, Williams, Catrin F., Lloyd, David, Duchêne, Michael

Journal:

Experimental Parasitology

Year:

2013

Language:

english

File:

PDF, 436 KB

english, 2013

21

Why Not a Patient Care Bundle? Improving Patient and Family Satisfaction by Bundling Evidence-Based Best Practices at the Bedside

McClarigan, Linda, Mader, David, Larabie, Shawn E., Gokey, Laura, Leitsch, Marilyn

Journal:

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

22

Pentamycin shows high efficacy against Trichomonas vaginalis

Kranzler, Markus, Syrowatka, Michael, Leitsch, David, Winnips, Cornelis, Walochnik, Julia

Journal:

International Journal of Antimicrobial Agents

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

23

Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds

Müller, Joachim, Rout, Samuel, Leitsch, David, Vaithilingam, Jathana, Hehl, Adrian, Müller, Norbert

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2015

Language:

english

File:

PDF, 517 KB

english, 2015

24

Drug Resistance in the Microaerophilic ParasiteGiardia lamblia

Journal:

Current Tropical Medicine Reports

Year:

2015

Language:

english

File:

PDF, 461 KB

english, 2015

25

Evaluation of Giardia lamblia thioredoxin reductase as drug activating enzyme and as drug target

Leitsch, David, Müller, Joachim, Müller, Norbert

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2016

Language:

english

File:

PDF, 531 KB

english, 2016

26

Editorial

Journal:

Molecular and Biochemical Parasitology

Year:

2016

Language:

english

File:

PDF, 79 KB

english, 2016

27

Ceres in intuitionistic logic

Cerna, David, Leitsch, Alexander, Reis, Giselle, Wolfsteiner, Simon

Journal:

Annals of Pure and Applied Logic

Year:

2017

Language:

english

File:

PDF, 761 KB

english, 2017

28

Drug susceptibility testing in microaerophilic parasites: Cysteine strongly affects the effectivities of metronidazole and auranofin, a novel and promising antimicrobial

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2017

Language:

english

File:

PDF, 639 KB

english, 2017

29

Giardia lamblia: missing evidence for a canonical thioredoxin system

Leitsch, David, Rout, Samuel, Lundström-Stadelmann, Britta, Balmer, Vreni, Hehl, Adrian, Müller, Norbert

Journal:

Parasitology Open

Year:

2017

Language:

english

File:

PDF, 246 KB

english, 2017

30

Establishment of a yeast-based VLP platform for antigen presentation

Wetzel, David, Rolf, Theresa, Suckow, Manfred, Kranz, Andreas, Barbian, Andreas, Chan, Jo-Anne, Leitsch, Joachim, Weniger, Michael, Jenzelewski, Volker, Kouskousis, Betty, Palmer, Catherine, Beeson, J

Journal:

Microbial Cell Factories

Year:

2018

Language:

english

File:

PDF, 2.23 MB

english, 2018

31

Redox Pathways as Drug Targets in Microaerophilic Parasites

Leitsch, David, Williams, Catrin F., Hrdý, Ivan

Journal:

Trends in Parasitology

Year:

2018

Language:

english

File:

PDF, 2.13 MB

english, 2018

32

Recent Advances in the Trichomonas vaginalis Field

Journal:

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

33

Activity of methylgerambullin from Glycosmis species (Rutaceae) against Entamoeba histolytica and Giardia duodenalis in vitro

Drinić, Mirjana, Raninger, Adriane, Zraunig, Andrea, Astelbauer, Florian, Leitsch, David, Obwaller, Andreas, Walochnik, Julia, Greger, Harald, Duchene, Michael

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2019

Language:

english

File:

PDF, 2.75 MB

english, 2019

34

Identification of the NADH-oxidase gene in Trichomonas vaginalis

Lamien-Meda, Aline, Leitsch, David

Journal:

Parasitology Research

Year:

2019

File:

PDF, 280 KB

2019

35

A novel 5-Plex qPCR-HRM assay detecting human diarrheal parasites

Lamien-Meda, Aline, Schneider, Renate, Walochnik, Julia, Auer, Herbert, Wiedermann, Ursula, Leitsch, David

Journal:

Year:

2020

File:

PDF, 1.37 MB

2020

36

Validation of reference genes for the normalization of RT-qPCR gene expression in Acanthamoeba spp.

KÃ¶hsler, Martina, Leitsch, David, MÃ¼ller, Norbert, Walochnik, Julia

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.27 MB

2020

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