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101

Synthesis and antiviral evaluation of some β-l-2′,3′-dideoxy-5-chloropyrimidine nucleosides and pronucleotides

Claire Pierra, Jean-Louis Imbach, Erik De Clercq, Jan Balzarini, Arthur Van Aerschot, Piet Herdewijn, Abdesslem Faraj, Anna G. Loi, Jean-Pierre Sommadossi, Gilles Gosselin

Journal:

Antiviral Research

Year:

2000

Language:

english

File:

PDF, 215 KB

english, 2000

102

Antiviral activity of Hawaiian medicinal plants against human immunodeficiency Virus Type-1 (HIV-1)

Christopher P. Locher, Myriam Witvrouw, Marie-Pierre De Béthune, Mark T. Burch, Howard F. Mower, Harry Davis, Aleidis Lasure, Rudi Pauwels, Erik De Clercq, Arnold J. Vlietinck

Journal:

Year:

1996

Language:

english

File:

PDF, 830 KB

english, 1996

103

Oxovanadium(IV) Cyclam and Bicyclam Complexes: Potential CXCR4 Receptor Antagonists

Ross, Allison, Soares, Dinesh C., Covelli, Danielle, Pannecouque, Christophe, Budd, Laura, Collins, Anna, Robertson, Neil, Parsons, Simon, De Clercq, Erik, Kennepohl, Pierre

Journal:

Inorganic Chemistry

Year:

2010

Language:

english

File:

PDF, 1.65 MB

english, 2010

104

Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity

Jan A.A.M Kamps, Pieter J Swart, Henriëtte W.M Morselt, Rudi Pauwels, Marie-Pierre De Béthune, Erik De Clercq, Dirk K.F Meijer, Gerrit L Scherphof

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1996

Language:

english

File:

PDF, 769 KB

english, 1996

105

Biological evaluation of epoxy analogs of 1α,25-dihydroxyvitamin D3

Katrien Allewaert, Xu-yang Zhao, Jie Zhao, Françoise Glibert, Dimitri Branisteanu, Pierre De Clercq, Maurits Vandewalle, Roger Bouillon

Journal:

Year:

1995

Language:

english

File:

PDF, 745 KB

english, 1995

106

The biological activity of 23-oxa-, 23-oxa-24-oxo-, and 23-thia-dihydroxyvitamin D3

Allewaert Katrien, Renilde Convents, Biauw Keng Tan, Suzanne Marcelis, Jie Zhao, Xu-yang Zhao, Pierre De Clercq, Maurits Vandewalle, Roger Bouillon

Journal:

Year:

1994

Language:

english

File:

PDF, 530 KB

english, 1994

107

Removal of C-ring from the CD-ring skeleton of 1α,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly

G. Satyanarayana Reddy, Matthew Robinson, Guochun Wang, G. Tayhas R. Palmore, Lynn Gennaro, Paul Vouros, Pierre De Clercq, Maurits Vandewalle, Wu Young, Shi Ling, Annemieke Verstuyf, Roger Bouillon

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 431 KB

english, 2007

108

Leader sequence of a plant ribosomal protein gene with complementarity to the 18S rRNA triggers in vitro cap-independent translation

Rudy Vanderhaeghen, Rebecca De Clercq, Mansour Karimi, Marc Van Montagu, Pierre Hilson, Mieke Van Lijsebettens

Journal:

Year:

2006

Language:

english

File:

PDF, 299 KB

english, 2006

109

Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1α,25-dihydroxyvitamin D analogs

Pierre J. De Clercq, Ibrahim Murad, Ling-Jie Gao, Yong-Jun Chen, Dirk Van Haver, Maurits Vandewalle, Annemieke Verstuyf, Lieve Verlinden, Christel Verboven, Roger Bouillon

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 88 KB

english, 2004

110

Altered Vitamin D receptor–coactivator interactions reflect superagonism of Vitamin D analogs

Guy Eelen, Lieve Verlinden, Mark Van Camp, Frank Claessens, Pierre De Clercq, Maurits Vandewalle, Roger Bouillon, Annemieke Verstuyf

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

111

The development of CD-ring modified analogs of 1α,25-dihydroxyvitamin D

Pierre J. De Clercq, Frederik De Buysser, Garrett Minne, Wim Schepens, Freek Vrielynck, Dirk Van Haver, Maurits Vandewalle, Annemieke Verstuyf, Roger Bouillon

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 335 KB

english, 2007

112

CD-ring modified vitamin D3 analogs and their superagonistic action

Guy Eelen, Lieve Verlinden, Roger Bouillon, Pierre De Clercq, Alberto Muñoz, Annemieke Verstuyf

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

113

Two alternative inocula to reproduce bluetongue virus serotype 8 disease in calves

Ludovic Martinelle, Fabiana Dal Pozzo, Pierre Sarradin, Ilse De Leeuw, Kris De Clercq, Christine Thys, Dominique Ziant, Etienne Thiry, Claude Saegerman

Journal:

Year:

2011

Language:

english

File:

PDF, 461 KB

english, 2011

114

Sequence analysis of a 24-kb contiguous genomic region at the Arabidopsis thaliana PFL locus on chromosome 1

Nancy Terryn, Pia Neyt, Rebecca De Clercq, Annick De Keyser, Hilde Van Den Daele, Wilson Ardiles, Patrice Déhais, Pierre Rouzé, Jan Gielen, Raimundo Villarroel, Marc Van Montagu

Journal:

Year:

1997

Language:

english

File:

PDF, 714 KB

english, 1997

115

Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1α

Paul Proost, Sofie Struyf, Dominique Schols, Christine Durinx, Anja Wuyts, Jean-Pierre Lenaerts, Erik De Clercq, Ingrid De Meester, Jo Van Damme

Journal:

Year:

1998

Language:

english

File:

PDF, 172 KB

english, 1998

116

Immune response of HLA DQ2 positive subjects, vaccinated with HBsAg/AS04, a hepatitis B vaccine with a novel adjuvant

Isabelle Desombere, Marie Van der Wielen, Pierre Van Damme, Michel Stoffel, Norbert De Clercq, Christian Goilav, Geert Leroux-Roels

Journal:

Year:

2002

Language:

english

File:

PDF, 54 KB

english, 2002

117

Sequence analysis of a 40-kb Arabidopsis thaliana genomic region located at the top of chromosome 1

Nancy Terryn, Jan Gielen, Annick De Keyser, Hilde Van Den Daele, Wilson Ardiles, Pia Neyt, Rebecca De Clercq, Jeroen Coppieters, Patrice Déhais, Raimundo Villarroel, Pierre Rouzé, Marc Van Montagu

Journal:

Year:

1998

Language:

english

File:

PDF, 81 KB

english, 1998

118

Synthesis and Biological Evaluation of 5-Substituted Derivatives of the Potent Antiherpes Agent (north)-Methanocarbathymine

Russ, Pamela, Schelling, Pierre, Scapozza, Leonardo, Folkers, Gerd, Clercq, Erik De, Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 281 KB

english, 2003

119

Mechanism of esterification of 1,3-dimethylamino alcohols by N-acetylimidazole in acetonitrile and the influence of alkyl and geminal dialkyl substitution upon the rate

Madder, Annemieke, Sebastian, Sonny, Van Haver, Dirk, J. De Clercq, Pierre, Maskill, Howard

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1997

Language:

english

File:

PDF, 133 KB

english, 1997

120

Novel Enantioselective Syntheses of (+)-Biotin

Deroose, Frederik D., Clercq, Pierre J. De

Journal:

Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 1.24 MB

english, 1995

121

Anti-complement activity of polynucleotides

Erik De Clercq, Paul F. Torrence, John Hobbs, Borek Janik, Pierre De Somer, Bernhard Witkop

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 468 KB

english, 1975

122

Synthesis of 2-Ethyl-19- nor Analogs of 1α,25-Dihydroxyvitamin D 3

Laplace, Duchan R., Van Overschelde, Michel, De Clercq, Pierre J., Verstuyf, Annemieke, Winne, Johan M.

Journal:

European Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 509 KB

english, 2013

123

Poly(rI) more important than poly(rC) in the interferon induction process by poly(rI)·poly(rC)

Erik De Clercq, William E. Stewart II, Pierre De Somer

Journal:

Year:

1973

Language:

english

File:

PDF, 418 KB

english, 1973

124

Purification and amino acid sequence of human motilin isolated from a motilin containing liver metastasis

Peggy De Clercq, André Vandermeers, Gert Van Assche, René Fiasse, Inge Depoortere, Marie-Claire Vandermeers-Piret, Pierre Deprez, Theo Peeters

Journal:

Regulatory Peptides

Year:

1995

Language:

english

File:

PDF, 398 KB

english, 1995

125

Synthesis, DNA binding and biological evaluation of synthetic precursors and novel analogs of netropsin

Debart, Francoise, Perigaud, Christian, Gosselin, Gilles, Mrani, Driss, Rayner, Bernard, Le Ber, Pierre, Auclair, Christian, Balzarini, Jan, De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 1.25 MB

english, 1989

126

New 3‘-Azido-3‘-deoxythymidin-5‘-yl O -( ω -Hydroxyalkyl) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation

Vlieghe, Patrick, Bihel, Frédéric, Clerc, Thierry, Pannecouque, Christophe, Witvrouw, Myriam, De Clercq, Erik, Salles, Jean-Pierre, Chermann, Jean-Claude, Kraus, Jean-Louis

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 116 KB

english, 2001

127

Biotin: A Timeless Challenge for Total Synthesis

De Clercq, Pierre J.

Journal:

Chemical Reviews

Year:

1997

Language:

english

File:

PDF, 2.79 MB

english, 1997

128

(.+-.)-Hysterin: revised structure and total synthesis

Demuynck, Marc, De Clercq, Pierre, Vandewalle, Maurits

Journal:

Journal of Organic Chemistry

Year:

1979

Language:

english

File:

PDF, 561 KB

english, 1979

129

Experimental co-infections of calves with bluetongue virus serotypes 1 and 8

Dal Pozzo, Fabiana, Martinelle, Ludovic, Thys, Christine, Sarradin, Pierre, De Leeuw, Ilse, Van Campe, Willem, De Clercq, Kris, Thiry, Etienne, Saegerman, Claude

Journal:

Veterinary Microbiology

Year:

2013

Language:

english

File:

PDF, 606 KB

english, 2013

130

The vitamin D analog TX527 ameliorates disease symptoms in a chemically induced model of inflammatory bowel disease

Verlinden, Lieve, Leyssens, Carlien, Beullens, Ine, Marcelis, Suzanne, Mathieu, Chantal, De Clercq, Pierre, Verstuyf, Annemieke

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 365 KB

english, 2013

131

Cell cycle arrest and apoptosis induced by 1α,25(OH)2D3 and TX 527 in Kaposi sarcoma is VDR dependent

González-Pardo, Verónica, Suares, Alejandra, Verstuyf, Annemieke, De Clercq, Pierre, Boland, Ricardo, Boland, Ana Russo de

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2014

Language:

english

File:

PDF, 993 KB

english, 2014

132

Pulmonary artery haemorrhage in newborn calves following bluetongue virus serotype 8 experimental infections of pregnant heifers

Martinelle, Ludovic, Dal Pozzo, Fabiana, Sarradin, Pierre, De Leeuw, Ilse, De Clercq, Kris, Thys, Christine, Thiry, Etienne, Saegerman, Claude

Journal:

Veterinary Microbiology

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

133

Increased Susceptibility of Cells Treated with Interferon to the Toxicity of Polyriboinosinic· Polyribocytidylic Acid

William E. Stewart, Erik De Clercq, Alfons Billiau, Jan Desmyter and Pierre De Somer

Journal:

Proceedings of the National Academy of Sciences

Year:

1972

Language:

english

File:

PDF, 557 KB

english, 1972

134

(.+-.)-Carpesiolin: total synthesis and structural determination

Kok, Piet, De Clercq, Pierre J., Vandewalle, Maurits E.

Journal:

Journal of Organic Chemistry

Year:

1979

Language:

english

File:

PDF, 715 KB

english, 1979

135

A Novel Short Convergent Entry into Himbacine Derivatives

Van Cauwenberge, Gunther, Gao, Ling-Jie, Van Haver, Dirk, Milanesio, Marco, Viterbo, Davide, De Clercq, Pierre J.

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

136

Surface Chemistry and Interface Formation during the Atomic Layer Deposition of Alumina from Trimethylaluminum and Water on Indium Phosphide

Adelmann, Christoph, Cuypers, Daniel, Tallarida, Massimo, Rodriguez, Leonard N. J., De Clercq, Astrid, Friedrich, Daniel, Conard, Thierry, Delabie, Annelies, Seo, Jin Won, Locquet, Jean-Pierre, De Gen

Journal:

Chemistry of Materials

Year:

2013

Language:

english

File:

PDF, 2.22 MB

english, 2013

137

Evaluation of a Two-Stage Screening Procedure in the Combinatorial Search for Serine Protease-Like Activity

Madder, Annemieke, Li, Liu, De Muynck, Hilde, Farcy, Nadia, Van Haver, Dirk, Fant, Franky, Vanhoenacker, Gerd, Sandra, Pat, Davis, Anthony P., De Clercq, Pierre J.

Journal:

Journal of Combinatorial Chemistry

Year:

2002

Language:

english

File:

PDF, 446 KB

english, 2002

138

New 3‘-Azido-3‘-deoxythymidin-5‘-yl O -(4-Hydroxyalkyl or -Alkenyl or -Alkylepoxide) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation

Vlieghe, Patrick, Clerc, Thierry, Pannecouque, Christophe, Witvrouw, Myriam, De Clercq, Erik, Salles, Jean-Pierre, Kraus, Jean-Louis

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 88 KB

english, 2001

139

Synthesis, Biological Activity, and Conformational Analysis of Four seco - d -15,19- bisnor -1α,25-Dihydroxyvitamin D Analogues, Diastereomeric at C17 and C20

Zhou, Xiaoming, Zhu, Gui-Dong, Van Haver, Dirk, Vandewalle, Maurits, De Clercq, Pierre J., Verstuyf, Annemieke, Bouillon, Roger

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 496 KB

english, 1999

140

A Pentaerythritol-Based Molecular Scaffold for Solid-Phase Combinatorial Chemistry

Farcy, Nadia, De Muynck, Hilde, Madder, Annemieke, Hosten, Noël, De Clercq, Pierre J.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 51 KB

english, 2001

141

Application of the B -Alkyl Suzuki−Miyaura Cross-Coupling Reaction to the Stereoselective Synthesis of Analogues of (3 S )-Oxidosqualene

Winne, Johan M., Guang, Bing, D'herd, Jo, De Clercq, Pierre J.

Journal:

Organic Letters

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

142

Synthesis of New Covalently Bound κ-Carrageenan−AZT Conjugates with Improved Anti-HIV Activities

Vlieghe, Patrick, Clerc, Thierry, Pannecouque, Christophe, Witvrouw, Myriam, De Clercq, Erik, Salles, Jean-Pierre, Kraus, Jean-Louis

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

143

SYNTHESIS AND ANTI-HIV ACTIVITY OF THYMIDINE ANALOGUES BEARING A 4?-CYANOVINYL GROUP AND SOME DERIVATIVES THEREOF

Tronchet, Jean, Kovacs, Imre, Dilda, Pierre, Seman, Michel, Andrei, Graciela, Snoeck, Robert, De Clercq, Erik, Balzarini, Jan

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2001

Language:

english

File:

PDF, 186 KB

english, 2001

144

Polyanion Inhibitors of Human Immunodeficiency Virus and Other Viruses. 5. Telomerized Anionic Surfactants Derived from Amino Acids †

Leydet, Alain, Barragan, Véronique, Boyer, Bernard, Montéro, Jean Louis, Roque, Jean Pierre, Witvrouw, Myriam, Este, José, Snoeck, Robert, Andrei, Graciela, De Clercq, Erick

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 371 KB

english, 1997

145

Polyene Cyclizations Related to Oxidosqualene Cyclization. A Model for the Anti-Markovnikov Closure of Ring C

Berckmoes, Karla, De Clercq, Pierre J., Viterbo, Davide

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 271 KB

english, 1995

146

Correction. Systematic Conformational Analysis. General Method for Rapid Conformational Evaluation. Its Application to the Hydroazulene System

De Clercq, Pierre

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 58 KB

english, 1981

147

Systematic conformational analysis. General method for rapid conformational evaluation. Its application to the hydroazulene system

De Clercq, Pierre J.

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 1.06 MB

english, 1981

148

Stepwise Approach toward First Generation Nonenzymatic Hydrolases

Madder, Annemieke, De Clercq, Pierre J., Declercq, Jean-Paul

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 288 KB

english, 1998

149

Synthesis of Spiro[4.5]decane CF-Ring Analogues of 1α,25-Dihydroxyvitamin D 3

Schepens, Wim, Van Haver, Dirk, Vandewalle, Maurits, Bouillon, Roger, Verstuyf, Annemieke, De Clercq, Pierre J.

Journal:

Organic Letters

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

150

Polyanion Inhibitors of HIV and Other Viruses. 7. Polyanionic Compounds and Polyzwitterionic Compounds Derived from Cyclodextrins as Inhibitors of HIV Transmission

Leydet, Alain, Moullet, Céline, Roque, Jean Pierre, Witvrouw, Myriam, Pannecouque, Christophe, Andrei, Graciela, Snoeck, Robert, Neyts, Johan, Schols, Dominique, De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 118 KB

english, 1998