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51

Structure–activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position

Emi Kobayashi, Mika Shimazaki, Yukiko Miyamoto, Hiroyuki Masuno, Keiko Yamamoto, Hector F. DeLuca, Sachiko Yamada, Masato Shimizu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

52

Synthesis and structure–activity relationships of 16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes

Hajime Takaku, Yukiko Miyamoto, Shiori Asami, Mika Shimazaki, Sachiko Yamada, Keiko Yamamoto, Nobuyuki Udagawa, Hector F. DeLuca, Masato Shimizu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 358 KB

english, 2008

53

2-Substituted-16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure

Masato Shimizu, Yukiko Miyamoto, Hajime Takaku, Mayumi Matsuo, Makoto Nakabayashi, Hiroyuki Masuno, Nobuyuki Udagawa, Hector F. DeLuca, Teikichi Ikura, Nobutoshi Ito

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

54

Synthesis and biological properties of 2-methylene-19-nor-25-dehydro-1α-hydroxyvitamin D3-26,23-lactones—weak agonists

Grazia Chiellini, Pawel Grzywacz, Lori A. Plum, Rafal Barycki, Margaret Clagett-Dame, Hector. F. DeLuca

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

55

13-Methyl-substituted des-C,D analogs of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): Synthesis and biological evaluation

Katarzyna Plonska-Ocypa, Rafal R. Sicinski, Lori A. Plum, Pawel Grzywacz, Jadwiga Frelek, Margaret Clagett-Dame, Hector F. DeLuca

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

56

Removal of the 20-methyl group from 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3 (2MD) selectively eliminates bone calcium mobilization activity

Rafal Barycki, Rafal R. Sicinski, Lori A. Plum, Pawel Grzywacz, Margaret Clagett-Dame, Hector F. DeLuca

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 926 KB

english, 2009

57

Vitamin D C-22 aldehydes. New key intermediates for the synthesis of side chain modified vitamin D analogues

Andrzej Kutner, Kato L. Perlman, Rafal R. Sicinski, Mary E. Phelps, Heinrich K. Schnoes, Hector F. DeLuca

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 240 KB

english, 1987

58

1α-Hydroxy-19-nor-vitamin D C-22 aldehyde. A valuable intermediate in the synthesis of side chain modifed 1α,25-dihydroxy-19-nor-vitamin D3

Kato L. Perlman, Hector F. DeLuca

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 206 KB

english, 1992

59

1α,25-dihydroxy-19-nor-vitamin D3, a novel vitamin D-related compound with potential therapeutic activity

Kato L. Perlman, Rafal R. Sicinski, Heinrich K. Schnoes, Hector F. DeLuca

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 89 KB

english, 1990

60

Three-dimensional structure-function relationship of vitamin D: Side chain location and various activities

Keiko Yamamoto, Hiroshi Ooizumi, Kazuhiko Umesono, Annemieke Verstuyf, Roger Bouillon, Hector F. DeLuca, Toshimasa Shinki, Tatsuo Suda, Sachiko Yamada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

61

Interaction between Vitamin D Receptor and Vitamin D Ligands: Two-Dimensional Alanine Scanning Mutational Analysis

Mihwa Choi, Keiko Yamamoto, Toshimasa Itoh, Makoto Makishima, David J Mangelsdorf, Dino Moras, Hector F DeLuca, Sachiko Yamada

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 741 KB

english, 2003

62

Model of three-dimensional structure of vitamin D receptor and its binding mechanism with 1α,25-dihydroxyvitamin D3

Piotr Rotkiewicz, Wanda Sicinska, Andrzej Kolinski, Hector F. DeLuca

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2001

Language:

english

File:

PDF, 594 KB

english, 2001

63

NMR assignments of tryptophan residue in apo and holo LBD-rVDR

Wanda Sicinska, William M. Westler, Hector F. DeLuca

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

64

Long term follow-up of bone mineral status in children with renal disease

Russell W. Chesney, Philip Rose, Richard B. Mazess, Hector F. DeLuca

Journal:

Pediatric Nephrology

Year:

1988

Language:

english

File:

PDF, 452 KB

english, 1988

65

Mechanism of action of 1,25-dihydroxyvitamin D3: 1990 version

Hector F. DeLuca

Journal:

Journal of Bone and Mineral Metabolism

Year:

1990

Language:

english

File:

PDF, 747 KB

english, 1990

66

Effect of ethane-1-hydroxy-1,1-diphosphonate and vitamin D on bone mineralization

Lee Ann Baxter, David J. Canty, George J. Bednar, Leonard Stern, Hector F. DeLuca, Donna L. Ginn, Larry Flora, Gordon S. Hassing

Journal:

Calcified Tissue International

Year:

1979

Language:

english

File:

PDF, 439 KB

english, 1979

67

2MD, a new anabolic agent for osteoporosis treatment

Lori A. Plum, Lorraine A. Fitzpatrick, Xiaohong Ma, Neil C. Binkley, Julia B. Zella, Margaret Clagett-Dame, Hector F. DeLuca

Journal:

Osteoporosis International

Year:

2006

Language:

english

File:

PDF, 451 KB

english, 2006

68

The Functional Metabolism and Molecular Biology of Vitamin D Action

Lori A. Plum, Hector F. DeLuca

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2009

Language:

english

File:

PDF, 617 KB

english, 2009

69

A new, highly sensitive assay for 1,25-dihydroxyvitamin D not requiring high-performance liquid chromatography: Application of monoclonal antibody against vitamin D receptor to radioreceptor assay

Hidenori Koyama, Jean M. Prahl, Ann Uhland, Masaki Nanjo, Masaaki Inaba, Yoshiki Nishizawa, Hirotoshi Morii, Yasuho Nishii, Hector F. DeLuca

Journal:

Analytical Biochemistry

Year:

1992

Language:

english

File:

PDF, 661 KB

english, 1992

70

Synthesis and biological activity of 22-iodo- and (E)-20(22)-dehydro analogues of 1α,25-dihydroxyvitamin D3

Rafal R. Sicinski, Hector F. DeLuca

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 287 KB

english, 1999

71

Evolution of our understanding of vitamin D

Hector F DeLuca

Journal:

Nutrition Reviews

Year:

2008

Language:

english

File:

PDF, 552 KB

english, 2008

72

Response to Vitamin D in Adrenalectomized Animals

CZARNOWSKA-MISZTAL, ELZBIETA, ZULL, J. ELWOOD, DELUCA, HECTOR F.

Journal:

Year:

1966

File:

PDF, 276 KB

1966

73

The kidney as an endocrine organ involved in calcium homeostasis

DeLuca, Hector F

Journal:

Kidney International

Year:

1973

File:

PDF, 757 KB

1973

74

Comparison of 1α-hydroxycholecalciferol and 25-hydroxycholecalciferol in the treatment of renal osteodystrophy: Greater effect of 25-hydroxycholecalciferol on bone mineralization

Fournier, Albert, Bordier, Philippe, Gueris, Jean, Sebert, Jean Luc, Marie, Pierre, Ferrière, Christine, Bedrossian, Jeanine, DeLuca, Hector F

Journal:

Kidney International

Year:

1979

File:

PDF, 822 KB

1979

75

Circulating vitamin D metabolite concentrations in childhood renal diseases

Chesney, Russell W, Hamstra, Alan J, Mazess, Richard B, Rose, Philip, DeLuca, Hector F

Journal:

Kidney International

Year:

1982

Language:

english

File:

PDF, 505 KB

english, 1982

76

Renal 25-hydroxyvitamin D3-1-hydroxylase in patients with renal disease

Satomura, Kenichi, Seino, Yoshiki, Yamaoka, Kanji, Tanaka, Yoshiyuki, Ishida, Makoto, Yabuuchi, Hyakuji, Tanaka, Yoko, DeLuca, Hector F

Journal:

Kidney International

Year:

1988

Language:

english

File:

PDF, 455 KB

english, 1988

77

Mechanism and Function of High Vitamin D Receptor Levels in Genetic Hypercalciuric Stone-Forming Rats

Alexander J Karnauskas, Johannes PTM van Leeuwen, Gert-Jan CM van den Bemd, Paru P Kathpalia, Hector F DeLuca, David A Bushinsky, Murray J Favus

Journal:

Journal of Bone and Mineral Research

Year:

2005

Language:

english

File:

PDF, 418 KB

english, 2005

78

A New Vitamin D Analog, 2MD, Restores Trabecular and Cortical Bone Mass and Strength in Ovariectomized Rats With Established Osteopenia

Hua Zhu Ke, Hong Qi, D Todd Crawford, Hollis A Simmons, Gang Xu, Mei Li, Lori Plum, Margaret Clagett-Dame, Hector F DeLuca, David D Thompson, Thomas A Brown

Journal:

Journal of Bone and Mineral Research

Year:

2005

Language:

english

File:

PDF, 1.13 MB

english, 2005

79

Effect of 2-Methylene-19-nor-(20S)-1α-Hydroxy-Bishomopregnacalciferol (2MbisP), an Analog of Vitamin D, on Secondary Hyperparathyroidism

Eduardo Slatopolsky, Jane L Finch, Alex J Brown, Cynthia S Ritter, Masahide Mizobuchi, Lori A Plum, Margaret Clagett-Dame, Rafal R Sicinski, Hector F DeLuca

Journal:

Journal of Bone and Mineral Research

Year:

2007

Language:

english

File:

PDF, 3.09 MB

english, 2007

80

Diaminobutane (DAB) Dendrimers Are Potent Binders of Oral Phosphate

Katie B Williams, Katarzyna Barycka, Julia B Zella, Hector F DeLuca

Journal:

Journal of Bone and Mineral Research

Year:

2009

Language:

english

File:

PDF, 983 KB

english, 2009

81

Hypophosphatemia and the Development of Rickets in Osteopetrotic (op/op) Mice

Laura C. Mccary, Connie M. Smith, Hector F. Deluca

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 372 KB

english, 1997

82

Association Between Intestinal Vitamin D Receptor, Calcium Absorption, and Serum 1,25 Dihydroxyvitamin D in Normal Young and Elderly Women

H. Karimi Kinyamu, J. Christopher Gallagher, Jean M. Prahl, Hector F. Deluca, Kimberly M. Petranick, Stephen J. Lanspa

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 348 KB

english, 1997

83

Thyrotropes in the pituitary are target cells for 1,25 dihydroxy vitamin D3

Madhabananda Sar, Walter E. Stumpf, Hector F. DeLuca

Journal:

Cell and Tissue Research

Year:

1980

Language:

english

File:

PDF, 1.17 MB

english, 1980

84

Target cells for 1,25 dihydroxyvitamin D3in the pancreas

Samuel A. Clark, Walter E. Stumpf, Madhabananda Sar, Hector F. DeLuca, Yoko Tanaka

Journal:

Cell and Tissue Research

Year:

1980

Language:

english

File:

PDF, 1.02 MB

english, 1980

85

The adrenal: A new target organ of the calciotropic hormone 1,25-dihydroxyvitamin D3

Samuel A. Clark, Walter E. Stumpf, Charles W. Bishop, Hector F. DeLuca, Dong H. Park, Tong H. Joh

Journal:

Cell and Tissue Research

Year:

1986

Language:

english

File:

PDF, 912 KB

english, 1986

86

Calcium homeostasis

Howard Rasmussen, Hector F. DeLuca

Journal:

Reviews of Physiology Biochemistry

Year:

1963

Language:

english

File:

PDF, 4.53 MB

english, 1963

87

Autoradiographic demonstration of target cells for 1,25-dihydroxycholecalciferol in the chick embryo chorioallantoic membrane, duodenum, and parathyroid glands

Roberto Narbaitz, Walter Stumpf, Madhabananda Sar, Hector F. DeLuca, Yoko Tanaka

Journal:

General and Comparative Endocrinology

Year:

1980

Language:

english

File:

PDF, 3.64 MB

english, 1980

88

A single receptor identical with that from intestine/T47D cells mediates the action of 1,25-dihydroxyvitamin D-3 in HL-60 cells

Hitoshi Goto, Kai-shun Chen, Jean M. Prahl, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1992

Language:

english

File:

PDF, 754 KB

english, 1992

89

A new member to the astasin family of metalloendopeptidases: A novel 1,25-dihydroxyvitamin D-3-stimulated mRNA from chorioallantoic membrane of quail

Mahmoud A. Elaroussi, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1994

Language:

english

File:

PDF, 697 KB

english, 1994

90

Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3

Kai-Shun Chen, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1994

Language:

english

File:

PDF, 736 KB

english, 1994

91

Cloning of the human 1α,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements

Kai-Shun Chen, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1995

Language:

english

File:

PDF, 1.21 MB

english, 1995

92

Transcriptional control of the osteocalcin gene by 1,25-dihydroxyvitamin D-2 and its 24-epimer in rat osteosarcoma cells

Nancy C. Arbour, Hisham M. Darwish, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1995

Language:

english

File:

PDF, 673 KB

english, 1995

93

Incorporation of retinoic acid into proteins via retinoyl-CoA

Britta Renstrom, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1989

Language:

english

File:

PDF, 896 KB

english, 1989

94

Kinetic properties of 25-hydroxyvitamin D- and 1.25-dihydroxyvitamin D-24-hydroxylase from chick kidney

Maria Burgos-Trinidad, Hector F. DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

File:

PDF, 403 KB

1991

95

Alterations in mRNA expression of duodenal 1,25-dihydroxyvitamin D3 receptor and vitamin D-dependent calcium binding protein in aged wistar rats

C.Tony Liang, Janice Barnes, Shunji Imanaka, Hector F. DeLuca

Journal:

Experimental Gerontology

Year:

1994

Language:

english

File:

PDF, 500 KB

english, 1994

96

1,25-Dihydroxyvitamin D3 regulates genes responsible for detoxification in intestine

Galina D. Kutuzova, Hector F. DeLuca

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 262 KB

english, 2007

97

Contribution of several metabolites of the vitamin D analog 20-epi-22-oxa-24a,26a,27a-tri-homo-1,25-(OH)2 vitamin D3 (KH 1060) to the overall biological activity of KH1060 by a shared mechanism of action

Gert-Jan C.M van den Bemd, F.Jeffrey Dilworth, Hugh L.J Makin, Jean M Prahl, Hector F Deluca, Glenville Jones, Huibert A.P Pols, Johannes P.T.M van Leeuwen

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 435 KB

english, 2000

98

Cloning and expression of the chicken 25-hydroxyvitamin D3 24-hydroxylase cDNA

Frédéric Jehan, Rohaizah Ismail, Kristine Hanson, Hector F DeLuca

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 494 KB

english, 1998

99

Functional Interference Between AP-1 and the Vitamin D Receptor on Osteocalcin Gene Expression in Human Osteosarcoma Cells

Tiina Jääskeläinen, Asta Pirskanen, Sanna Ryhänen, Jorma J. Palvimo, Hector F. Deluca, Pekka H. Mäenpää

Journal:

Year:

1994

Language:

english

File:

PDF, 1.17 MB

english, 1994

100

Metabolites of All-trans-Retinol in Day 10 Conceptuses of Vitamin A-Deficient Rats

Deneen M. Wellik, Hector F. DeLuca

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 132 KB

english, 1996