Dean Naisbitt: search on Z-Library

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51

Dapsone and nitroso dapsone activation of naïve T-cells from healthy donors

Alzahrani, Abdulaziz, Ogese, Monday O., Meng, Xioali, Waddington, James, Tailor, Arun, Farrell, John, Maggs, James L, Betts, Catherine J., Park, B. Kevin, Naisbitt, Dean John

Journal:

Chemical Research in Toxicology

Year:

2017

Language:

english

File:

PDF, 1.59 MB

english, 2017

52

Drug Metabolite-Specific Lymphocyte Responses in Sulfamethoxazole Allergic Patients with Cystic Fibrosis

Lavergne, Sidonie N., Whitaker, Paul, Peckham, Daniel, Conway, Steve, Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

53

Immunological principles of T-cell-mediated adverse drug reactions in skin

Naisbitt, Dean J, Pirmohamed, Munir, Park, B Kevin

Journal:

Expert Opinion on Drug Safety

Year:

2007

Language:

english

File:

PDF, 547 KB

english, 2007

54

Immune Drug-induced Liver Disease and Drugs

Waddington, James C., Meng, Xiaoli, Naisbitt, Dean J., Kevin Park, B.

Journal:

Current Opinion in Toxicology

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

55

Drug presentation to T cells

Naisbitt, Dean John, Pirmohamed, Munir, Park, Brian Kevin

Journal:

Journal of Allergy and Clinical Immunology

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

56

Characterization of drug-specific lymphocyte responses in a patient with drug-induced liver injury

El-Ghaiesh, Sabah, Sanderson, Joseph P., Farrell, John, Lavergne, Sidonie N., Syn, Wing-Kin, Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 989 KB

english, 2011

57

Immunological Principles of Adverse Drug Reactions

Dr Dean J. Naisbitt, S. Fraser Gordon, Munir Pirmohamed, B. Kevin Park

Journal:

Year:

2000

Language:

english

File:

PDF, 309 KB

english, 2000

58

Activation of carbamazepine-responsive T-cell clones with metabolically inert halogenated derivatives

Farrell, John, Lichtenfels, Maike, Sullivan, Andrew, Elliott, Emma C., Alfirevic, Ana, Stachulski, Andrew V., Pirmohamed, Munir, Naisbitt, Dean J., Park, B. Kevin

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 677 KB

english, 2013

59

Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury

Kim, Seung-Hyun, Saide, Katy, Farrell, John, Faulkner, Lee, Tailor, Arun, Ogese, Monday, Daly, Ann K., Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.

Journal:

Year:

2015

Language:

english

File:

PDF, 983 KB

english, 2015

60

Detection of Drug-Responsive T-Lymphocytes in a Case of Fatal Antituberculosis Drug-Related Liver Injury

Usui, Toru, Whitaker, Paul, Meng, Xiaoli, Watson, John, Antoine, Daniel J., French, Neil S., Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

61

IL-8 Release from Human Neutrophils Cultured with Pro-Haptenic Chemical Sensitizers

Kiorpelidou, Eva, Foster, Brian, Farrell, John, Ogese, Monday O., Faulkner, Lee, Goldring, Chris E., Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 459 KB

english, 2012

62

Detection of Drug Bioactivation in Vivo: Mechanism of Nevirapine–Albumin Conjugate Formation in Patients

Meng, Xiaoli, Howarth, Alice, Earnshaw, Caroline J., Jenkins, Rosalind E., French, Neil S., Back, David J., Naisbitt, Dean J., Park, B. Kevin

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 2.63 MB

english, 2013

63

Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients

Meng, Xiaoli, Al-Attar, Zaid, Yaseen, Fiazia S., Jenkins, Rosalind, Earnshaw, Caroline, Whitaker, Paul, Peckham, Daniel, French, Neil S., Naisbitt, Dean J., Park, B. Kevin

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.73 MB

english, 2017

64

Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo

Tailor, Arun, Waddington, James C., Hamlett, Jane, Maggs, James, Kafu, Laila, Farrell, John, Dear, Gordon J., Whitaker, Paul, Naisbitt, Dean J., Park, Kevin, Meng, Xiaoli

Journal:

Chemical Research in Toxicology

Year:

2019

Language:

english

File:

PDF, 6.94 MB

english, 2019

65

Characterization of amoxicillin and clavulanic acid specific T-cell clones from patients with immediate drug hypersensitivity

Ariza, Adriana, FernÃ¡ndez-SantamarÃa, RubÃ©n, Meng, Xiaoli, Salas, MarÃa, Ogese, Monday O, Tailor, Arun, Bogas, GÃ¡dor, Torres, MarÃa JosÃ©, Naisbitt, Dean J

Journal:

Year:

2020

File:

PDF, 1.48 MB

2020

66

Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo

Dean J Naisbitt, S Fraser Gordon, Munir Pirmohamed, Christoph Burkhart, Alistair E Cribb, Werner J Pichler, B Kevin Park

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 299 KB

english, 2001

67

Drug hypersensitivity reactions in patients with HIV disease

Pirmohamed, Munir, Drummond, Nicola S, Naisbitt, Dean J, Park, B Kevin

Journal:

Expert Review of Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 460 KB

english, 2007

68

HLA-A*33:03-restricted activation of ticlopidine-specific T-cells from human donors

Usui, Toru, Tailor, Arun, Faulkner, Lee, Meng, Xiaoli, Farrell, John, Daly, Ann K., Dear, Gordon J., Park, B. Kevin, Naisbitt, Dean John

Journal:

Chemical Research in Toxicology

Year:

2018

Language:

english

File:

PDF, 375 KB

english, 2018

69

Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells

Josephine E. Hopkins, Dean J. Naisbitt, Neil Humphreys, Rebecca J. Dearman, Ian Kimber, B. Kevin Park

Journal:

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

70

Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity

Dean J Naisbitt, Sally J Hough, Helen J Gill, Munir Pirmohamed, Neil R Kitteringham, B Kevin Park

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 388 KB

english, 1999

71

Investigation of the immunogenicity of p-phenylenediamine and Bandrowski's base in the mouse

John Farrell, Claire Jenkinson, Sidonie N. Lavergne, James L. Maggs, B. Kevin Park, Dean J. Naisbitt

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 726 KB

english, 2009

72

A Mechanistic Investigation into the Irreversible Protein Binding and Antigenicity of p -Phenylenediamine

Jenkinson, Claire, Jenkins, Rosalind E., Maggs, James L., Kitteringham, Neil R., Aleksic, Maja, Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 2.29 MB

english, 2009

73

Correction: Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients

Meng, Xiaoli, Al-Attar, Zaid, Yaseen, Fiazia S., Jenkins, Rosalind, Earnshaw, Caroline, Whitaker, Paul, Peckham, Daniel, French, Neil S., Naisbitt, Dean J., Park, B. Kevin

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 478 KB

english, 2018

74

Involvement of drug-specific CD4+ and CD8+ T-cells in trimethoprim-mediated hepatitis

Sabah El-Ghaiesh, Sidonie Lavergne, John Farell, Wing Syn, Munir Pirmohamed, B. Kevin Park, Dean J. Naisbitt

Journal:

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

75

Immune pathomechanism of drug hypersensitivity reactions

Pichler, Werner J., Naisbitt, Dean J., Park, B. Kevin

Journal:

Journal of Allergy and Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 396 KB

english, 2011

76

Metabolic and Chemical Origins of Cross-Reactive Immunological Reactions to Arylamine Benzenesulfonamides: T-Cell Responses to Hydroxylamine and Nitroso Derivatives

Castrejon, J. Luis, Lavergne, Sidonie N., El-Sheikh, Ayman, Farrell, John, Maggs, James L., Sabbani, Sunil, O’Neill, Paul M., Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 687 KB

english, 2010

77

Abacavir Forms Novel Cross-Linking Abacavir Protein Adducts in Patients

Meng, Xiaoli, Lawrenson, Alexandre S., Berry, Neil G., Maggs, James L., French, Neil S., Back, David J., Khoo, Saye H., Naisbitt, Dean J., Park, B. Kevin

Journal:

Chemical Research in Toxicology

Year:

2014

Language:

english

File:

PDF, 5.61 MB

english, 2014

78

Nonimmediate β-lactam reactions in patients with cystic fibrosis

Whitaker, Paul, Naisbitt, Dean, Peckham, Daniel

Journal:

Current Opinion in Allergy and Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 393 KB

english, 2012

79

UP-REGULATION OF T - CELL ACTIVATION MICRORNAS IN DRUG-SPECIFIC CD4+ T - CELLS FROM HYPERSENSITIVE PATIENTS

Monroy-Arreola, Alejandra, Duran-Figueroa, Noe, Mendez-Flores, Silvia, Dominguez-Cherit, Judith, Watkinson, Joel, Badillo-Corona, Agustin, Whitaker, Paul, Naisbitt, Dean, Castrejon Flores, Luis

Journal:

Chemical Research in Toxicology

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

80

Biopsy pathology and immunohistochemistry of a case of immuneâmediated drugâinduced liver injury with Atabecestat

DeÂ Jonghe, Sandra, Weinstock, Daniel, Aligo, Jason, Washington, Kay, Naisbitt, Dean

Journal:

Year:

2020

File:

PDF, 8.25 MB

2020

81

Drug hypersensitivity reactions in skin: understanding mechanisms and the development of diagnostic and predictive tests

Dean J. Naisbitt

Journal:

Year:

2004

Language:

english

File:

PDF, 468 KB

english, 2004

82

Development of an improved T cell assay to assess the intrinsic immunogenicity of haptenic compounds

Ogese, Monday O, Watkinson, Joel, Lister, Adam, Faulkner, Lee, Gibson, Andrew, Hillegas, Aimee, Sakatis, Melanie Z, Park, B Kevin, Naisbitt, Dean J

Journal:

Toxicological Sciences

Year:

2020

File:

PDF, 2.05 MB

2020

83

Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells

Christoph Burkhart, Salome Von Greyerz, Jan P H Depta, Dean J Naisbitt, Markus Britschgi, Kevin B Park, Werner J Pichler

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 171 KB

english, 2001

84

Characterization of Peroxidases Expressed in Human Antigen Presenting Cells and Analysis of the Covalent Binding of Nitroso Sulfamethoxazole to Myeloperoxidase

Ogese, Monday O., Jenkins, Rosalind E., Maggs, James L., Meng, Xiaoli, Whitaker, Paul, Peckham, Daniel, Faulkner, Lee, Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 3.56 MB

english, 2015

85

Trimethoprim-induced aseptic meningism

Lochlainn, Mary Ni, Gooi, Hock C, Ogese, Monday O, Naisbitt, Dean J, Jafar-Mohammadi, Bahram

Journal:

British Journal of Hospital Medicine

Year:

2017

Language:

english

File:

PDF, 145 KB

english, 2017

86

Assessment of Antipiperacillin IgG Binding to Structurally Related Drug Protein Adducts

Amali, Mohammed O., Jenkins, Rosalind E., Meng, Xiaoli, Faulkner, Lee, Whitaker, Paul, Peckham, Daniel, Park, B. Kevin, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2017

Language:

english

File:

PDF, 307 KB

english, 2017

87

Characterization of drug-specific T cells in lamotrigine hypersensitivity

Naisbitt, Dean J., Farrell, John, Wong, Gavin, Depta, Jan p.H., Dodd, Charlotte C., Hopkins, Josephine E., Gibney, Claire A., Chadwick, David W., Pichler, Werner J., Pirmohamed, Munir, Park, B.Kevin

Journal:

Journal of Allergy and Clinical Immunology

Year:

2003

Language:

english

File:

PDF, 626 KB

english, 2003

88

HLA Restriction of Carbamazepine-Specific T-Cell Clones from an HLA-A*31:01-Positive Hypersensitive Patient

Lichtenfels, Maike, Farrell, John, Ogese, Monday O., Bell, Catherine C., Eckle, Sidonia, McCluskey, James, Park, B. Kevin, Alfirevic, Ana, Naisbitt, Dean J., Pirmohamed, Munir

Journal:

Chemical Research in Toxicology

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

89

Characterization of isoniazid-specific T-cell clones in patients with anti-tuberculosis drug-related liver and skin injury

Usui, Toru, Meng, Xiaoli, Saide, Katy, Farrell, John, Thomson, Paul, Whitaker, Paul, Watson, John, French, Neil S., Park, B. Kevin, Naisbitt, Dean J.

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 911 KB

english, 2016

90

Human leukocyte antigen and idiosyncratic adverse drug reactions

Usui, Toru, Naisbitt, Dean J.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 537 KB

english, 2017

91

A chemically inert drug can stimulate T cells in vitro by their T cell receptor in non-sensitised individuals

Olivier B Engler, Ingrid Strasser, Dean J Naisbitt, Andreas Cerny, Werner J Pichler

Journal:

Year:

2004

Language:

english

File:

PDF, 191 KB

english, 2004

92

Selective Haptenation of Cellular or Extracellular Protein by Chemical Allergens: Association with Cytokine Polarization

Hopkins, Josephine E., Naisbitt, Dean J., Kitteringham, Neil R., Dearman, Rebecca J., Kimber, Ian, Park, B. Kevin

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 315 KB

english, 2005

93

Plasma Cysteine Deficiency and Decreased Reduction of Nitrososulfamethoxazole with HIV Infection

Naisbitt, Dean J., Vilar, F. Javier, Stalford, Anne C., Wilkins, Edmund G. L., Pirmohamed, Munir, Park, B. Kevin

Journal:

AIDS Research and Human Retroviruses

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

94

Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA‐B*57:01 binding and T‐cell activation

Thomson, Paul J., Illing, Patricia T., Farrell, John, Alhaidari, Mohammad, Bell, Catherine C., Berry, Neil, O’Neill, Paul M., Purcell, Anthony W., Park, Kevin B., Naisbitt, Dean J.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.20 MB

english, 2019

95

Characterization of p-Phenylenediamine–Albumin Binding Sites and T-Cell Responses to Hapten-Modified Protein

Jenkinson, Claire, Jenkins, Rosalind E, Aleksic, Maja, Pirmohamed, Munir, Naisbitt, Dean J, Park, B Kevin

Journal:

The Journal of Investigative Dermatology

Year:

2009

Language:

english

File:

PDF, 583 KB

english, 2009

96

Correction: The Effect of Inhibitory Signals on the Priming of Drug Hapten–Specific T Cells That Express Distinct Vβ Receptors

Gibson, Andrew, Faulkner, Lee, Lichtenfels, Maike, Ogese, Monday, Al-Attar, Zaid, Alfirevic, Ana, Esser, Philipp R., Martin, Stefan F., Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 589 KB

english, 2018

97

T-cell activation by low molecular weight drugs and factors that influence susceptibility to drug hypersensitivity

Hammond, Sean, Thomson, Paul J., Ogese, Monday O., Naisbitt, Dean John

Journal:

Chemical Research in Toxicology

Year:

2019

File:

PDF, 1.22 MB

2019

98

Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury

Gibson, Andrew, Hammond, Sean, Jaruthamsophon, Kanoot, Roth, Sharin, Mosedale, Merrie, Naisbitt, Dean J.

Journal:

Chemical Research in Toxicology

Year:

2020

File:

PDF, 2.44 MB

2020

99

Oxidative Bioactivation of Abacavir in Subcellular Fractions of Human Antigen Presenting Cells

Bell, Catherine C., Santoyo Castelazo, Anahi, Yang, Emma L., Maggs, James L., Jenkins, Rosalind E., Tugwood, Jonathan, O’Neill, Paul M., Naisbitt, Dean J., Park, B. Kevin

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 760 KB

english, 2013

100

Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions?

Sullivan, Andrew, Gibson, Andrew, Park, Brian Kevin, Naisbitt, Dean J

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2015

Language:

english

File:

PDF, 542 KB

english, 2015

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