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51

Necitumumab in the treatment of advanced non-small cell lung cancer: translation from preclinical to clinical development

Dienstmann, Rodrigo, Felip, Enriqueta

Journal:

Expert Opinion on Biological Therapy

Year:

2011

Language:

english

File:

PDF, 242 KB

english, 2011

52

Genomic Medicine Frontier in Human Solid Tumors: Prospects and Challenges

Dienstmann, R., Rodon, J., Barretina, J., Tabernero, J.

Journal:

Journal of Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 275 KB

english, 2013

53

Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors

Juric, D., Dienstmann, R., Cervantes, A., Hidalgo, M., Messersmith, W., Blumenschein, G. R., Tabernero, J., Roda, D., Calles, A., Jimeno, A., Wang, X., Bohorquez, S. S., Leddy, C., Littman, C., Kapp,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

54

Panitumumab: a summary of clinical development in colorectal cancer and future directions

Argiles, Guillem, Dienstmann, Rodrigo, Elez, Elena, Tabernero, Josep

Journal:

Future Oncology

Year:

2012

Language:

english

File:

PDF, 692 KB

english, 2012

55

Spectrum of Gene Mutations in Colorectal Cancer

Dienstmann, Rodrigo, Tabernero, Josep

Journal:

The Cancer Journal

Year:

2016

Language:

english

File:

PDF, 252 KB

english, 2016

56

KRAS mutations(m) in lung adenocarcinoma (AC) patients(p) receiving standard chemotherapy (ch) and immune checkpoint inhibitors (i-CI): Impact of KRAS clonality and coexisting TP53m

Aranda, N. Pardo, Ruiz, F., Marti, A. Martinez, Cedres, S., Mendivil, A. Navarro, fuente, I. de la, de Castro, A. Martinez, Vivancos, A., Dienstmann, R., Felip, E.

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 64 KB

english, 2016

57

Personalizing Adjuvant Therapy for Stage II/III Colorectal Cancer

McCleary, Nadine Jackson, Benson, Al B., Dienstmann, Rodrigo

Journal:

American Society of Clinical Oncology Educational Book

Year:

2017

Language:

english

File:

PDF, 675 KB

english, 2017

58

Development of Molecular Biomarkers in Individualized Treatment of Colorectal Cancer

Leticia De Mattos-Arruda, Rodrigo Dienstmann, Josep Tabernero

Journal:

Clinical Colorectal Cancer

Year:

2011

Language:

english

File:

PDF, 1.11 MB

english, 2011

59

619 Results of the First-in-human Phase I Study of GDC-0068, an Akt Inhibitor That Demonstrates Safe and Sustained Targeting of the PI3K/Akt Pathway in Patients (pts) with Advanced Solid Tumors

Cervantes, A., Saura, C., Roda, D., Dienstmann, R., Rosello, S., Carles, J., Funke, R., Zhu, J., Meng, R., Tabernero, J.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

60

BRAF as a Target for Cancer Therapy

Dienstmann, Rodrigo, Tabernero, Josep

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

61

219P Outcomes of malignant pleural mesothelioma (MPM) patients (p) treated after first line chemotherapy (CT)

Cedres, S., Amair, F., Martinez-Marti, A., Navarro, A., Pardo, N., Remon-Masip, J., Miquel, J.M., Villacampa, G., Dienstmann, R., Font, E. Felip

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 94 KB

english, 2018

62

ESÔFAGO NEGRO COMO COMPLICAÇÃO PÓS‐OPERATÓRIA DE RETOSSIGMOIDECTOMIA ABDOMINAL: RELATO DE CASO

Michaelsen, Marlise Mello Cerato, Valentini, Kamyla Griebeler, Koshimizu, Ruy Takashi, Vila, Rafael Dienstmann Dutra, Passos, Patricia da Silva, Bonamigo, Karine Sabrina, Visioli, Marja Luciane

Journal:

Journal of Coloproctology (Rio de Janeiro)

Year:

2018

File:

PDF, 165 KB

2018

63

Precision oncology: separating the wheat from the chaff

Remon, Jordi, Dienstmann, Rodrigo

Journal:

Year:

2018

Language:

english

File:

PDF, 297 KB

english, 2018

64

923PValidation of the VIO prognostic index in patients with metastatic urothelial carcinoma treated with immune-checkpoint inhibitors

Morales Barrera, R, Matos, I, Gonzalez, M, Suárez, C, Ros, J, Valverde, C, Fernandez, C, Hierro, C, Serra, E, Mateo, J, Gutierrez, S, Martín Liberal, J, Quintana, A, Dienstmann, R, Serrano, C, Garrald

Journal:

Annals of Oncology

Year:

2019

File:

PDF, 87 KB

2019

65

580 First-in-human, Safety, Pharmacokinetic (PK) and Pharmacodynamic (PD) Results From a Phase I Study of a Selective BRAF Inhibitor (BRAFi) RG7256 in Patients with BRAF V600-mutated Advanced Solid Tumors

Dienstmann, R., Lassen, U., Cebon, J., Desai, J., Brown, M.P., Evers, S., Su, F., Zhang, W., Meresse, V., Tabernero, J.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 75 KB

english, 2012

66

TGR Analysis in Phase I Clinical Trials--Letter

Dienstmann, R., Tabernero, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 106 KB

english, 2014

67

123PGenotyping circulating tumor DNA identifies metastatic colorectal cancer (mCRC) patients highly sensitive to Sym004

Montagut Viladot, C., Bardelli, A., Tuxen Poulsen, T., Dienstmann, R., Kragh, M., Kopetz, S., Koefoed, K., Ciardiello, F., Ding, C., Vidal, J., Clausell-Tormos, J., Siravegna, G., Lindsted, T., Peders

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 52 KB

english, 2017

68

First-in-Man Dose-Escalation Study of the Selective BRAF Inhibitor RG7256 in Patients with BRAF V600-Mutated Advanced Solid Tumors

Dienstmann, Rodrigo, Lassen, Ulrik, Cebon, Jonathan, Desai, Jayesh, Brown, Michael P., Evers, Stefan, Su, Fei, Zhang, Weijiang, Boisserie, Frederic, Lestini, Brian, Schostack, Kathleen, Meresse, Valer

Journal:

Targeted Oncology

Year:

2016

Language:

english

File:

PDF, 650 KB

english, 2016

69

Cancer: A precision approach to tumour treatment

Dienstmann, Rodrigo, Tabernero, Josep

Journal:

Year:

2017

Language:

english

File:

PDF, 811 KB

english, 2017

70

Pharmacokinetic/Pharmacodynamic Modeling for Drug Development in Oncology

Garralda, Elena, Dienstmann, Rodrigo, Tabernero, Josep

Journal:

American Society of Clinical Oncology Educational Book

Year:

2017

Language:

english

File:

PDF, 813 KB

english, 2017

71

RNF43 - and NOTCH1 -Mutated Chemotherapy and Anti–EGFR-Refractory Colorectal Cancer: Should Clonality Guide Target Prioritization With Investigational Therapies?

Aguilar, Susana, Santos, Cristina, Martini, Giulia, Argiles, Guillem, Azaro, Analia, Garralda, Elena, Tabernero, Josep, Nuciforo, Paolo, Vivancos, Ana, Dienstmann, Rodrigo

Journal:

JCO Precision Oncology

Year:

2019

Language:

english

File:

PDF, 475 KB

english, 2019

72

Precision therapy in RAS mutant colorectal cancer

Dienstmann, R., Connor, K., Byrne, A.T., Fridman, W.H., Lambrechts, D., Sadanandam, A., Trusolino, L., Prehn, J.H.M., Tabernero, J., Kolch, W.

Journal:

Gastroenterology

Year:

2020

Language:

english

File:

PDF, 2.77 MB

english, 2020

73

Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors

Dienstmann, R., Rodon, J., Prat, A., Perez-Garcia, J., Adamo, B., Felip, E., Cortes, J., Iafrate, A. J., Nuciforo, P., Tabernero, J.

Journal:

Annals of Oncology

Year:

2014

Language:

english

File:

PDF, 296 KB

english, 2014

74

Biomarker-driven patient selection for early clinical trials

Dienstmann, Rodrigo, Rodon, Jordi, Tabernero, Josep

Journal:

Current Opinion in Oncology

Year:

2013

Language:

english

File:

PDF, 219 KB

english, 2013

75

A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations

Tamborero, David, Rubio-Perez, Carlota, Muiños, Ferran, Sabarinathan, Radhakrishnan, Piulats, Josep Maria, Muntasell, Aura, Dienstmann, Rodrigo, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 6.48 MB

english, 2018

76

Combined Modality Therapy of Stage IIIC Breast Cancer

Rodrigo Dienstmann, Luís Guilherme Branco, Lígia M. Rezende, Leila C. Freitas, Carlos Frederico Lima, Guilherme J. Rodrigues, Hélio Noronha Filho, Roberta B. Sarmento, Isabele Small, José Bines

Journal:

The Breast Journal

Year:

2011

Language:

english

File:

PDF, 59 KB

english, 2011

77

Molecular Profiling of Patients with Colorectal Cancer and Matched Targeted Therapy in Phase I Clinical Trials

Dienstmann, R., Serpico, D., Rodon, J., Saura, C., Macarulla, T., Elez, E., Alsina, M., Capdevila, J., Perez-Garcia, J., Sanchez-Olle, G., Aura, C., Prudkin, L., Landolfi, S., Hernandez-Losa, J., Viva

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 541 KB

english, 2012

78

Database of Genomic Biomarkers for Cancer Drugs and Clinical Targetability in Solid Tumors

Dienstmann, R., Jang, I. S., Bot, B., Friend, S., Guinney, J.

Journal:

Cancer Discovery

Year:

2015

Language:

english

File:

PDF, 550 KB

english, 2015

79

Tankyrase inhibition blocks Wnt/ -catenin pathway and reverts resistance to PI3K and AKT inhibitors in the treatment of colorectal cancer

Arques, O., Chicote, I., Puig, I., Tenbaum, S. P., Argiles, G., Dienstmann, R., Fernandez, N., Caratu, G., Matito, J., Silberschmidt, D., Rodon, J., Landolfi, S., Prat, A., Espin, E., Charco, R., Nuci

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 10.01 MB

english, 2015

80

[WORLD SCIENTIFIC Proceedings of the Pacific Symposium - Kohala Coast, Hawaii, USA (4 – 8 January 2015)] Biocomputing 2015 - STEPWISE GROUP SPARSE REGRESSION (SGSR): GENE-SET-BASED PHARMACOGENOMIC PREDICTIVE MODELS WITH STEPWISE SELECTION OF FUNCTIONAL PRIORS

JANG, IN SOCK, DIENSTMANN, RODRIGO, MARGOLIN, ADAM A., GUINNEY, JUSTIN

Language:

english

File:

PDF, 3.73 MB

english

81

Effectiveness of Metformin in the Prevention of Gestational Diabetes Mellitus in Obese Pregnant Women

Sales, Willian, Nascimento, Iramar, Dienstmann, Guilherme, Souza, Matheus, Silva, Grazielle, Silva, Jean

Journal:

Revista Brasileira de Ginecologia e Obstetrícia

Year:

2018

File:

PDF, 208 KB

2018

82

Predictive modeling in colorectal cancer: time to move beyond Consensus Molecular Subtypes

Sveen, A, Cremolini, C, Dienstmann, R

Journal:

Annals of Oncology

Year:

2019

File:

PDF, 459 KB

2019

83

Fusobacterium nucleatum persistence and risk of recurrence after preoperative treatment in locally advanced rectal cancer

Serna, G., Ruiz-Pace, F., Hernando, J., Alonso, L., Fasani, R., Landolfi, S., Comas, R., Jimenez, J., Elez, E., Bullman, S., Meyerson, M., Tabernero, J., Capdevila, J., Dienstmann, R., Nuciforo, P.

Journal:

Annals of Oncology

Year:

2020

File:

PDF, 7.31 MB

2020

84

No effect of a low dose of metformin on the lipid profile, body mass index and weight gain in pregnant women with obesity: A randomized trial

Dienstmann, Guilherme, Nascimento, Iramar Baptistella do, Sales, Willian Barbosa, Leite Ramos de Souza, Matheus, Silva, Grazielle Dutra da, de Oliveira, Larissa Cano, Silva, Jean Carl

Journal:

Obesity Research & Clinical Practice

Year:

2020

File:

PDF, 472 KB

2020

85

Assessment of the recycling potential of fresh concrete waste using a factorial design of experiments

S.L. Correia, F.L. Souza, G. Dienstmann, A.M. Segadães

Journal:

Waste Management

Year:

2009

Language:

english

File:

PDF, 310 KB

english, 2009

86

XAF1 mRNA expression improves progression-free and overall survival for patients with advanced bladder cancer treated with neoadjuvant chemotherapy

Marcos B. Pinho, Fernanda Costas, João Sellos, Rodrigo Dienstmann, Patricia B. Andrade, Daniel Herchenhorn, Fábio Afonso Peixoto, Valdelice O. Santos, Isabele A. Small, Denise P. Guimarães, Carlos G.

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

2009

Language:

english

File:

PDF, 526 KB

english, 2009

87

Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study

Dienstmann, R., Mason, M. J., Sinicrope, F. A., Phipps, A. I., Tejpar, S., Nesbakken, A., Danielsen, S. A., Sveen, A., Buchanan, D. D., Clendenning, M., Rosty, C., Bot, B., Alberts, S. R., Milburn Jes

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

88

988PBenefit from subsequent conventional cytotoxic chemotherapy (CTx) to immunotherapy (IT) in patients (pts) with gynaecological malignancies (GM)

Ros Montañá, F J, Rodriguez Freixinos, V, Fariñas Madrid, L, Amair Pinedo, F, Ruiz-Pace, F, Garralda, E, Dienstmann, R, Oaknin, A

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 79 KB

2018

89

Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer

Dienstmann, Rodrigo, Salazar, Ramon, Tabernero, Josep

Journal:

American Society of Clinical Oncology Educational Book

Year:

2015

Language:

english

File:

PDF, 227 KB

english, 2015

90

Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials

Dienstmann, Rodrigo, Garralda, Elena, Aguilar, Susana, Sala, Gemma, Viaplana, Cristina, Ruiz-Pace, Fiorella, GonzÃ¡lez-Zorelle, Jenifer, Grazia LoGiacco, Deborah, Ogbah, Zighereda, Ramos Masdeu, Laia,

Journal:

JCO Precision Oncology

Year:

2020

File:

PDF, 730 KB

2020

91

L6.3 Molecular Characterization and Pre-Screening Process in Early Drug Clinical Development of PI3K-Pathway Inhibitors

Rodon, J., Dienstmann, R., Cortes, J., Saura, C., Aura, C., HernÃ¡ndez-Losa, J., Vivancos, A., Joan, J., del Campo, J., Felip, E., Seoane, J., Tabernero, J.T.

Journal:

Annals of Oncology

Year:

2012

File:

PDF, 120 KB

2012

92

Outcomes of systemic therapy after first line therapy in patients (p) with malignant pleural mesothelioma (MPM)

Cedres, S., Iranzo, P., Callejo, A., Pardo, N., Navarro, A., Martinez-Marti, A., Saoudi Gonzalez, N., Valdivia, A., Monton, V., Gonzalo, J., Pedrola, A., Dienstmann, R., Felip, E.

Journal:

Annals of Oncology

Year:

2020

File:

PDF, 74 KB

2020

93

Drug development to overcome resistance to EGFR inhibitors in lung and colorectal cancer

Rodrigo Dienstmann, Sara De Dosso, Enriqueta Felip, Josep Tabernero

Journal:

Molecular Oncology

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

94

979PAchievement of complete response (CR) in metastatic or recurrent cervical cancer (MRCC): Does it matter?

Grau Béjar, J.F., Rodriguez Freixinos, V., Fariñas Madrid, L., Villacampa Javierre, G., Gil-Moreno, A., Verges, R., Pérez Benavente, M.A., García, A., Dienstmann, R., Oaknin, A.

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 83 KB

english, 2017

95

117PImmunoscore feasibility study in routine postsurgical pathologic review for early-stage colon cancer (CC) cases risk-assessment

Belaloui, K, Malifarge, E, Bohm, J, Bossard, C, Dienstmann, R, Garcia, S, Geppert, C, Gogenur, I, Hartmann, A, Hatzibougias, D, Landolfi, S, Mishaeli, M, Paez, D, Patel, P, Rodriguez-Justo, M, Szafran

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 74 KB

2018

96

Application of Monoclonal Antibodies as Cancer Therapy in Solid Tumors

Dienstmann, Rodrigo, Markman, Ben, Tabernero, Josep

Journal:

Current Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 168 KB

english, 2012

97

Avaliação fenotípica da enzima Klebsiella pneumoniae carbapenemase (KPC) em Enterobacteriaceae de ambiente hospitalar

Dienstmann, Rosabel, Picoli, Simone Ulrich, Meyer, Gabriela, Schenkel, Tiago, Steyer, Juçara

Journal:

Jornal Brasileiro de Patologia e Medicina Laboratorial

Year:

2010

File:

PDF, 129 KB

2010

98

2 Agents Targeting the mTOR-PI3K-Akt Pathway

Tabernero, J., Dienstmann, R., Macarulla, T., Saura, C., Argiles, G., Alsina, M., Cruz, C., Brana, I., Cortes, J., Rodon, J.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

99

Molecular subtypes and the evolution of treatment management in metastatic colorectal cancer

Martini, Giulia, Dienstmann, Rodrigo, Ros, Javier, Baraibar, Iosune, Cuadra-Urteaga, Jose Luis, Salva, Francesc, Ciardiello, Davide, Mulet, Nuria, Argiles, Guillem, Tabernero, Josep, Elez, Elena

Journal:

Therapeutic Advances in Medical Oncology

Year:

2020

File:

PDF, 779 KB

2020

100

Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial

Bines, J., Dienstmann, R., Obadia, R. M., Branco, L. G. P., Quintella, D. C., Castro, T. M., Camacho, P. G., Soares, F. A., Costa, M. E. F.

Journal:

Annals of Oncology

Year:

2014

Language:

english

File:

PDF, 170 KB

english, 2014

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