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51

Native Dimer Stabilizes the Subunit Tertiary Structure of Porcine Class pi Glutathione S-transferase

Julija Erhardt, Heini Dirr

Journal:

Year:

1995

Language:

english

File:

PDF, 787 KB

english, 1995

52

Amide hydrogen exchange in HIV-1 subtype B and C proteases - insights into reduced drug susceptibility and dimer stability

Naicker, Previn, Stoychev, Stoyan, Dirr, Heini W., Sayed, Yasien

Journal:

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

53

A Phosphomimetic Study Implicates Ser557 in Regulation of FOXP2 DNA Binding

Blane, Ashleigh, Dirr, Heini W., Fanucchi, Sylvia

Journal:

The Protein Journal

Year:

2018

Language:

english

File:

PDF, 1.79 MB

english, 2018

54

The hydrophobic lock-and-key intersubunit motif of glutathione transferase A1-1: implications for catalysis, ligandin function and stability

Yasien Sayed, Louise A. Wallace, Heini W. Dirr

Journal:

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

55

F99 is Critical for Dimerization and Activation of South African HIV-1 Subtype C Protease

Naicker, Previn, Seele, Palesa, Dirr, Heini W., Sayed, Yasien

Journal:

The Protein Journal

Year:

2013

Language:

english

File:

PDF, 502 KB

english, 2013

56

Influence of the Dimer Interface on Glutathione Transferase Structure and Dynamics Revealed by Amide H/D Exchange Mass Spectrometry †

Codreanu, Simona G., Thompson, Lawrence C., Hachey, David L., Dirr, Heini W., Armstrong, Richard N.

Journal:

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

57

Stability of the domain interface contributes towards the catalytic function at the H-site of class alpha glutathione transferase A1-1

David Balchin, Sylvia Fanucchi, Ikechukwu Achilonu, Roslin J. Adamson, Jonathan Burke, Manuel Fernandes, Samantha Gildenhuys, Heini W. Dirr

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2010

Language:

english

File:

PDF, 696 KB

english, 2010

58

High yield purification of JNK1β1 and activation by in vitro reconstitution of the MEKK1→MKK4→JNK MAPK phosphorylation cascade

Owen, Gavin R., Achilonu, Ikechukwu, Dirr, Heini W.

Journal:

Protein Expression and Purification

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

59

S- Nitrosation Destabilizes Glutathione Transferase P1-1

Balchin, David, Stoychev, Stoyan H., Dirr, Heini W.

Journal:

Year:

2013

Language:

english

File:

PDF, 506 KB

english, 2013

60

Structural insights into the South African HIV-1 subtype C protease: impact of hinge region dynamics and flap flexibility in drug resistance

Naicker, Previn, Achilonu, Ikechukwu, Fanucchi, Sylvia, Fernandes, Manuel, Ibrahim, Mahmoud A.A., Dirr, Heini W., Soliman, Mahmoud E.S., Sayed, Yasien

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

2013

Language:

english

File:

PDF, 511 KB

english, 2013

61

Class Pi Glutathione Transferase Unfolds via a Dimeric and Not Monomeric Intermediate: Functional Implications for an Unstable Monomer

Gildenhuys, Samantha, Wallace, Louise A., Burke, Jonathan P., Balchin, David, Sayed, Yasien, Dirr, Heini W.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

62

Equilibrium Folding of Dimeric Class μ Glutathione Transferases Involves a Stable Monomeric Intermediate †

Hornby, Judith A. T., Luo, Jiann-Kae, Stevens, Julie M., Wallace, Louise A., Kaplan, Warren, Armstrong, Richard N., Dirr, Heini W.

Journal:

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

63

Formation of an Unfolding Intermediate State of Soluble Chloride Intracellular Channel Protein CLIC1 at Acidic pH †

Fanucchi, Sylvia, Adamson, Roslin J., Dirr, Heini W.

Journal:

Year:

2008

Language:

english

File:

PDF, 960 KB

english, 2008

64

Phosphorylation- and Nucleotide-Binding-Induced Changes to the Stability and Hydrogen Exchange Patterns of JNK1β1 Provide Insight into Its Mechanisms of Activation

Owen, Gavin R., Stoychev, Stoyan, Achilonu, Ikechukwu, Dirr, Heini W.

Journal:

Journal of Molecular Biology

Year:

2014

Language:

english

File:

PDF, 3.86 MB

english, 2014

65

A Conserved Interdomain Interaction Is a Determinant of Folding Cooperativity in the GST Fold

Parbhoo, Nishal, Stoychev, Stoyan H., Fanucchi, Sylvia, Achilonu, Ikechukwu, Adamson, Roslin J., Fernandes, Manuel, Gildenhuys, Samantha, Dirr, Heini W.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

66

Structural Dynamics of Soluble Chloride Intracellular Channel Protein CLIC1 Examined by Amide Hydrogen−Deuterium Exchange Mass Spectrometry

Stoychev, Stoyan H., Nathaniel, Christos, Fanucchi, Sylvia, Brock, Melissa, Li, Sheng, Asmus, Kyle, Woods, Virgil L., Dirr, Heini W.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.51 MB

english, 2009

67

The effects of mutating Tyr9 and Arg15 on the structure, stability, conformational dynamics and mechanism of GSTA3-3

Robertson, Gary J., Stoychev, Stoyan H., Sayed, Yasien, Achilonu, Ikechukwu, Dirr, Heini W.

Journal:

Biophysical Chemistry

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

68

The study of degradation mechanisms of glyco-engineered plant produced anti-rabies monoclonal antibodies E559 and 62-71-3

Buthelezi, Sindisiwe G., Dirr, Heini W., Chakauya, Ereck, Chikwamba, Rachel, Martens, Lennart, Tsekoa, Tsepo L., Vandermarliere, Elien, Stoychev, Stoyan H., Kaur, Balveen

Journal:

Year:

2018

Language:

english

File:

PDF, 3.72 MB

english, 2018

69

Double trouble? Gag in conjunction with double insert in HIV protease contribute to reduced DRV susceptibility

Williams, Alison, Basson, Adriaan, Achilonu, Ikechukwu, Dirr, Heini W., Morris, Lynn, Sayed, Yasien

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 493 KB

english, 2018

70

Structure Determination and Refinement of Human Alpha Class Glutathione Transferase A1-1, and a Comparison with the Mu and Pi Class Enzymes

Irmgard Sinning, Gerard J. Kleywegt, Sandra W. Cowan, Peter Reinemer, Heini W. Dirr, Robert Huber, Gary L. Gilliland, Richard N. Armstrong, Xinhua Ji, Philip G. Board, Birgit Olin, Bengt Mannervik, T.

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 1.22 MB

1993

71

The Cochaperone Murine Stress-Inducible Protein 1: Overexpression, Purification, and Characterization

Jacqueline van der Spuy, Michael E. Cheetham, Heini W. Dirr, Gregory L. Blatch

Journal:

Protein Expression and Purification

Year:

2001

Language:

english

File:

PDF, 224 KB

english, 2001

72

Molecular dynamics and ligand docking of a hinge region variant of South African HIV-1 subtype C protease

Zondagh, Jake, Balakrishnan, Vijayakumar, Achilonu, Ikechukwu, Dirr, Heini W., Sayed, Yasien

Journal:

Journal of Molecular Graphics and Modelling

Year:

2018

Language:

english

File:

PDF, 6.49 MB

english, 2018

73

Electrostatic interactions affecting the active site of class Sigma glutathione S-transferase

STEVENS, Julie M., ARMSTRONG, Richard N., DIRR, Heini W.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

74

Stability and Unfolding of Reduced Escherichia coli Glutaredoxin 2: A Monomeric Structural Homologue of the Glutathione Transferase Family †

Gildenhuys, Samantha, Wallace, Louise A., Dirr, Heini W.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.58 MB

english, 2008

75

The role of an evolutionarily conserved cis-proline in the thioredoxin-like domain of human class Alpha glutathione transferase A1-1

NATHANIEL, Chris, WALLACE, Louise A., BURKE, Jonathan, DIRR, Heini W.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 163 KB

english, 2003

76

Accessibility of the tryptophan residues and flavin prosthetic group of β-cyclopiazonate oxidocyclase to solvent studied by fluorescence quenching

Heini W. Dirr, Gerdinand L. Erasmus, Johan C. Schabort

Journal:

International Journal of Biochemistry

Year:

1988

Language:

english

File:

PDF, 261 KB

english, 1988

77

Purification and properties of an esterase from Cucurbita maxima fruit tissue

Amanda Nourse, Johan C. Schabort, Heini W. Dirr, Ian A. Dubery

Journal:

Year:

1989

Language:

english

File:

PDF, 721 KB

english, 1989

78

Purification and partial characterization of the glutathione S-transferase of rat erythrocytes

Heini W. Dirr, Johan C. Schabort

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1988

Language:

english

File:

PDF, 721 KB

english, 1988

79

Class π glutathione S-transferase from pig lung : Purification, biochemical characterization, primary structure and crystallization

Heini W. DIRR, Karlheinz MANN, Robert HUBER, Rudi LADENSTEIN, Peter REINEMER

Journal:

Year:

1991

Language:

english

File:

PDF, 661 KB

english, 1991

80

The Lyssavirus glycoprotein: A key to cross-immunity

Buthelezi, Sindisiwe G., Dirr, Heini W., Chakauya, Ereck, Chikwamba, Rachel, Martens, Lennart, Tsekoa, Tsepo L., Stoychev, Stoyan H., Vandermarliere, Elien

Journal:

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

81

Role of Arginine 29 and Glutamic Acid 81 Interactions in the Conformational Stability of Human Chloride Intracellular Channel 1

Legg-E’Silva, Derryn, Achilonu, Ikechukwu, Fanucchi, Sylvia, Stoychev, Stoyan, Fernandes, Manuel, Dirr, Heini W.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.03 MB

english, 2012

82

A Single Amino Acid in the Hinge Loop Region of the FOXP Forkhead Domain is Significant for Dimerisation

Perumal, Kershia, Dirr, Heini W., Fanucchi, Sylvia

Journal:

The Protein Journal

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

83

Conformational stability of pGEX-expressed Schistosoma japonicum glutathione S-transferase: A detoxification enzyme and fusion-protein affinity tag

Warren Kaplan, Julija Erhardt, Nicolas Sluis-Cremer, Heini Dirr, Paul Hüsler, Horst Klump

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 2.17 MB

english, 1997

84

Characterization of the aflatoxin B1-binding site of rat albumin

Heini W. Dirr, Johannes C. Schabort

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1987

Language:

english

File:

PDF, 625 KB

english, 1987

85

Aflatoxin B1 and sulphobromophthalein binding to the dimeric human glutathione S-transferase A1-1 : a fluorescence spectroscopic analysis

Nicolas Sluis-Cremer, Louise Wallace, Jonathan Burke, Julie Stevens, Heini Dirr

Journal:

Year:

1998

Language:

english

File:

PDF, 265 KB

english, 1998

86

Refined Crystal Structure of Porcine Class Pi Glutathione S-Transferase (pGST P1-1) at 2·1 Å Resolution

Heini Dirr, Peter Reinemer, Robert Huber

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 1.53 MB

1994

87

Tertiary Interactions Stabilise the C-terminal Region of Human Glutathione Transferase A1-1: a Crystallographic and Calorimetric Study

Diane C. Kuhnert, Yasien Sayed, Salerwe Mosebi, Muhammed Sayed, Trevor Sewell, Heini W. Dirr

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 516 KB

english, 2005

88

Molecular Recognition at the Dimer Interface of a Class Mu Glutathione Transferase: Role of a Hydrophobic Interaction Motif in Dimer Stability and Protein Function †

Hornby, Judith A. T., Codreanu, Simona G., Armstrong, Richard N., Dirr, Heini W.

Journal:

Year:

2002

Language:

english

File:

PDF, 327 KB

english, 2002

89

An update on the biophysical character of the human eukaryotic elongation factor 1 beta: Perspectives from interaction with elongation factor 1 gamma

Achilonu, Ikechukwu, Elebo, Nnenna, Hlabano, Babongiwe, Owen, Gavin R., Papathanasopoulos, Maria, Dirr, Heini W.

Journal:

Journal of Molecular Recognition

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

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