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51

Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand

Michelle L. James, Roger R. Fulton, David J. Henderson, Stefan Eberl, Steven R. Meikle, Sally Thomson, Robin D. Allan, Frederic Dolle, Michael J. Fulham, Michael Kassiou

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 251 KB

english, 2005

52

Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET

Frédéric Dollé, Patrick Emond, Sylvie Mavel, Stéphane Demphel, Françoise Hinnen, Zoïa Mincheva, Wadad Saba, Heric Valette, Sylvie Chalon, Christer Halldin, Julie Helfenbein, Joël Legaillard, Jean-Clau

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

53

Synthesis and radiosynthesis of [18F]FPhEP, a novel α4β2-selective, epibatidine-based antagonist for PET imaging of nicotinic acetylcholine receptors

Gaëlle Roger, Wadad Saba, Héric Valette, Françoise Hinnen, Christine Coulon, Michèle Ottaviani, Michel Bottlaender, Frédéric Dollé

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 275 KB

english, 2006

54

Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands

Johnny Vercouillie, Sylvie Mavel, Laurent Galineau, Tiziana Ragusa, Robert Innis, Michael Kassiou, Sylvie Chalon, Frédéric Dollé, Jean-Claude Besnard, Denis Guilloteau, Patrick Emond

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 121 KB

english, 2006

55

Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO)

Aaron Reynolds, Raphy Hanani, David Hibbs, Annelaure Damont, Eleonora Da Pozzo, Silvia Selleri, Frédéric Dollé, Claudia Martini, Michael Kassiou

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010

56

A convergent synthesis of 2′-o-methyl uridine

Gilles Parmentier, Gaby Schmitt, Frédéric Dolle, Bang Luu

Journal:

Year:

1994

Language:

english

File:

PDF, 602 KB

english, 1994

57

Synthesis of the phosphodiester of 3β(7β-hydroxycholesterol) and of 5′(3′deoxy, 3′azido-thymidine).

Xavier Pannecoucke, Gilles Parmentier, Gaby Schmitt, Frédéric Dolle, Bang Luu

Journal:

Year:

1994

Language:

english

File:

PDF, 463 KB

english, 1994

58

Synthesis of a tritiated 3-dehydroecdysteroid putative precursor of ecdysteroid biosynthesis

Frédéric Dolle, Charles Hetru, Bernard Rousseau, Frank Sobrio, Catherine Blais, René Lafont, Michel Descamp, Bang Luu

Journal:

Year:

1993

Language:

english

File:

PDF, 1.07 MB

english, 1993

59

Synthesis and in vivo imaging properties of [11C]befloxatone: A novel highly potent positron emission tomography ligand for mono-amine oxidase-A

Frédéric Dolle, Héric Valette, Yann Bramoulle, Ilonka Guenther, Chantal Fuseau, Christine Coulon, Carole Lartizien, Samir Jegham, Pascal George, Olivier Curet, Jean-Louis Pinquier, Michel Bottlaender

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

60

Synthesis of [11C]RPR-72840A and its evaluation as a radioligand for the serotonin reuptake site in positron emission tomography

Dirk Roeda, Bertrand Tavitian, Christine Coulon, Frédérique David, Frédéric Dollé, Chantal Fuseau, Antoinette Jobert, Christian Crouzel

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 765 KB

english, 1997

61

Synthesis of two optically active calcium channel antagonists labelled with carbon-11 for in vivo cardiac PET imaging

Frédéric Dollé, Françoise Hinnen, Héric Valette, Chantal Fuseau, Raphaël Duval, Jean-Louis Péglion, Christian Crouzel

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.22 MB

english, 1997

62

Long-lasting occupancy of central nicotinic acetylcholine receptors after smoking: a PET study in monkeys

Héric Valette, Michel Bottlaender, Frédéric Dollé, Christine Coulon, Michèle Ottaviani, André Syrota

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

63

Pharmacological evaluation of a Br-76 analog of epibatidine: A potent ligand for studying brain nicotinic acetylcholine receptors

Michael Kassiou, Michel Bottlaender, Christian Loc'h, Frederic Dolle, John L. Musachio, Christine Coulon, Michele Ottaviani, Robert F. Dannals, Bernard Maziere

Journal:

Year:

2002

Language:

english

File:

PDF, 1.27 MB

english, 2002

64

Acute effects of physostigmine and galantamine on the binding of [18F]fluoro-A-85380: A PET study in monkeys

Héric Valette, Michel Bottlaender, Frédéric Dollé, Christine Coulon, Michèle Ottaviani, André Syrota

Journal:

Year:

2005

Language:

english

File:

PDF, 72 KB

english, 2005

65

[11C]LBT-999: A suitable radioligand for investigation of extra-striatal dopamine transporter with PET

Wadad Saba, Héric Valette, Marie-Anne Schöllhorn-Peyronneau, Christine Coulon, Michele Ottaviani, Sylvie Chalon, Frédéric Dolle, Patrick Emond, Christer Halldin, Julie Helfenbein, Jean-Claude Madelmon

Journal:

Year:

2007

Language:

english

File:

PDF, 204 KB

english, 2007

66

[18F]FPhEP and [18F]F2PhEP, two new epibatidine-based radioligands: Evaluation for imaging nicotinic acetylcholine receptors in baboon brain

Héric Valette, Frédéric Dollé, Wadad Saba, Gaelle Roger, Françoise Hinnen, Christine Coulon, Michele Ottaviani, André Syrota, Michel Bottlaender

Journal:

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

67

[11C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: Preclinical characterisation in nonhuman primate

Wadad Saba, Héric Valette, Marie-Anne Peyronneau, Yann Bramoullé, Christine Coulon, Olivier Curet, Pascal George, Frédéric Dollé, Michel Bottlaender

Journal:

Year:

2010

Language:

english

File:

PDF, 425 KB

english, 2010

68

[18F]ZW-104, a new radioligand for imaging α2-α3-α4/β2 central nicotinic acetylcholine receptors: Evaluation in mutant mice

Wadad Saba, Héric Valette, Sylvie Granon, Yingxian Xiao, Kenneth J. Kellar, Frédéric Dollé, Michel Bottlaender

Journal:

Year:

2010

Language:

english

File:

PDF, 136 KB

english, 2010

69

In vivo biodistribution and pharmacokinetics of18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals

Raphaël Boisgard, Bertrand Kuhnast, Stefan Vonhoff, Chéraz Younes, Françoise Hinnen, Jean-Marc Verbavatz, Bernard Rousseau, Jens Peter Fürste, Britta Wlotzka, Frédéric Dollé, Sven Klussmann, Bertrand

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2005

Language:

english

File:

PDF, 351 KB

english, 2005

70

Biodistribution and radiation dosimetry of [11C]raclopride in healthy volunteers

Maria-João Ribeiro, Marcel Ricard, Sandrine Bourgeois, Marie-Angele Lièvre, Michel Bottlaender, Philippe Gervais, Frédéric Dollé, André Syrota

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

71

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers

Fabien Chauveau, Hervé Boutin, Nadja Van Camp, Frédéric Dollé, Bertrand Tavitian

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2008

Language:

english

File:

PDF, 330 KB

english, 2008

72

PET imaging of medullary thyroid carcinoma in MEN2A transgenic mice using 6-[18F]F-L-DOPA

Carine Pestourie, Benoît Thézé, Bertrand Kuhnast, Stéphane Le Helleix, Karine Gombert, Frédéric Dollé, Bertrand Tavitian, Frédéric Ducongé

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

73

In vivo imaging of neuroinflammation: a comparative study between [18F]PBR111, [11C]CLINME and [11C]PK11195 in an acute rodent model

Nadja Van Camp, Raphael Boisgard, Bertrand Kuhnast, Benoit Thézé, Thomas Viel, Marie-Claude Grégoire, Fabien Chauveau, Hervé Boutin, Andrew Katsifis, Frédéric Dollé, Bertrand Tavitian

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2010

Language:

english

File:

PDF, 620 KB

english, 2010

74

In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18

Fabien Chauveau, Hervé Boutin, Nadja Van Camp, Cyrille Thominiaux, Philippe Hantraye, Luc Rivron, Frank Marguet, Marie-Noëlle Castel, Thomas Rooney, Jesus Benavides, Frédéric Dollé, Bertrand Tavitian

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2011

Language:

english

File:

PDF, 352 KB

english, 2011

75

Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714

Abraham Martín, Raphaël Boisgard, Michael Kassiou, Frédéric Dollé, Bertrand Tavitian

Journal:

Molecular Imaging and Biology

Year:

2011

Language:

english

File:

PDF, 284 KB

english, 2011

76

Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases

Alex Sik Chung Ching, Bertrand Kuhnast, Annelaure Damont, Dirk Roeda, Bertrand Tavitian, Frédéric Dollé

Journal:

Insights into Imaging

Year:

2012

Language:

english

File:

PDF, 587 KB

english, 2012

77

Synthesis of high specific activity [3H2-1,2]-7-dehydrocholesterol. Conversion to ecdysone in follicle cells of locusta (Insects)

Dolle Frédéric, Kappler Christine, Hetru Charles, Rousseau Bernard, Coppo Michéle, Luu Bang, Jules A. Hoffmann

Journal:

Year:

1990

Language:

english

File:

PDF, 841 KB

english, 1990

78

Synthesis of a tritiated 3-dehydroecdysteroid putative precursor of ecdysteroid biosynthesis in Locusta migratoria

Frédéric Dolle, Charles Hetru, Jean-Pierre Roussel, Bernard Rousseau, Franck3 Sobrio, Bang Luu, Jules A. Hoffmann

Journal:

Year:

1991

Language:

english

File:

PDF, 913 KB

english, 1991

79

A new route to precursors of ecdysteroids using a regio- and stereoselective hydroboration

Frédéric Dolle, Charles Hetru, Bang Luu

Journal:

Year:

1991

Language:

english

File:

PDF, 516 KB

english, 1991

80

Synthesis of a [6-Pyridinyl-18F]-labelled fluoro derivative of WAY-100635 as a candidate radioligand for brain 5-HT1A receptor imaging with PET

Mylène Karramkam, Françoise Hinnen, Myriam Berrehouma, Christophe Hlavacek, Françoise Vaufrey, Christer Halldin, Julie A. McCarron, Victor W. Pike, Frédéric Dollé

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 393 KB

english, 2003

81

Synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor PET imaging

Lilian Dolci, Frédéric Dolle, Héric Valette, Françoise Vaufrey, Chantal Fuseau, Michel Bottlaender, Christian Crouzel

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 403 KB

english, 1999

82

Striatal and extrastriatal dopamine transporter in cannabis and tobacco addiction: a high-resolution PET study

Claire Leroy, Laurent Karila, Jean-Luc Martinot, Michaël Lukasiewicz, Edouard Duchesnay, Claude Comtat, Frédéric Dollé, Amine Benyamina, Eric Artiges, Maria-Joao Ribeiro, Michel Reynaud, Christian Tri

Journal:

Addiction Biology

Year:

2012

Language:

english

File:

PDF, 619 KB

english, 2012

83

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

Matthes, Hans W. D., Maldonado, Rafael, Simonin, Frédéric, Valverde, Olga, Slowe, Susan, Kitchen, Ian, Befort, Katia, Dierich, Andrée, Le Meur, Marianne, Dollé, Pascal

Journal:

Year:

1996

File:

PDF, 1.49 MB

1996

84

Evaluation of the PBR/TSPO radioligand [18F]DPA-714 in a rat model of focal cerebral ischemia

Martín, Abraham, Boisgard, Raphaël, Thézé, Benoit, Van Camp, Nadja, Kuhnast, Bertrand, Damont, Annelaure, Kassiou, Michael, Dollé, Frédéric, Tavitian, Bertrand

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2009

Language:

english

File:

PDF, 727 KB

english, 2009

85

In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [11C]befloxatone and the multi-injection approach

Bottlaender, Michel, Valette, Héric, Delforge, Jacques, Saba, Wadad, Guenther, Ilonka, Curet, Olivier, George, Pascal, Dollé, Frédéric, Grégoire, Marie-Claude

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2009

Language:

english

File:

PDF, 464 KB

english, 2009

86

Decrease of nicotinic receptors in the nigrostriatal system in Parkinson's disease

Kas, Aurélie, Bottlaender, Michel, Gallezot, Jean Dominique, Vidailhet, Marie, Villafane, Gabriel, Grégoire, Marie Claude, Coulon, Christine, Valette, Héric, Dollé, Frédéric, Ribeiro, Maria-Joao

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

87

In vivo imaging of oligonucleotides with positron emission tomography

Tavitian, Bertrand, Terrazzino, Salvatore, Kühnast, Bertrand, Marzabal, Stéphane, Stettler, Olivier, Dollé, Fréderic, Deverre, Jean-robert, Jobert, Antoinette, Hinnen, Françoise, Bendriem, Bernard

Journal:

Nature Medicine

Year:

1998

File:

PDF, 671 KB

1998

88

Multiinjection approach for D2 receptor binding quantification in living rats using [11C]raclopride and the β-microprobe: crossvalidation with in vitro binding data

Mauger, Gweltas, Saba, Wadad, Hantraye, Philippe, Dolle, Frédéric, Coulon, Christine, Bramoulle, Yann, Chalon, Sylvie, Gregoire, Marie-Claude

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2005

Language:

english

File:

PDF, 229 KB

english, 2005

89

Quantification of cerebral nicotinic acetylcholine receptors by PET using 2-[18F]fluoro-A-85380 and the multiinjection approach

Syrota, André, Gallezot, Jean-Dominique, Bottlaender, Michel A, Delforge, Jacques, Valette, Héric, Saba, Wadad, Dollé, Frédéric, Coulon, Christine M, Ottaviani, Michèle P, Hinnen, Françoise

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2007

Language:

english

File:

PDF, 469 KB

english, 2007

90

Characterization of a Synthetic Anionic Vector for Oligonucleotide Delivery Usingin VivoWhole Body Dynamic Imaging

Bertrand Tavitian, Stéphane Marzabal, Valérie Boutet, Bertrand Kühnast, Salvatore Terrazzino, Marinette Moynier, Frédéric Dollé, Jean Robert Deverre, Alain R. Thierry

Journal:

Pharmaceutical Research

Year:

2002

Language:

english

File:

PDF, 2.78 MB

english, 2002

91

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

Alexandra Winkeler, Raphael Boisgard, Ali R. Awde, Albertine Dubois, Benoit Thézé, Jinzi Zheng, Luisa Ciobanu, Frédéric Dollé, Thomas Viel, Andreas H. Jacobs, Bertrand Tavitian

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2012

Language:

english

File:

PDF, 698 KB

english, 2012

92

[18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106—Selective radioligands for imaging TSPO 18 kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls

Bertrand Kuhnast, Annelaure Damont, Françoise Hinnen, Tony Catarina, Stéphane Demphel, Stéphane Le Helleix, Christine Coulon, Sébastien Goutal, Philippe Gervais, Frédéric Dollé

Journal:

Applied Radiation and Isotopes

Year:

2012

Language:

english

File:

PDF, 604 KB

english, 2012

93

Synthesis of fluorine-18-labelled TSPO ligands for imaging neuroinflammation with Positron Emission Tomography

Dirk Roeda, Bertrand Kuhnast, Annelaure Damont, Frédéric Dollé

Journal:

Journal of Fluorine Chemistry

Year:

2012

Language:

english

File:

PDF, 415 KB

english, 2012

94

In vivo validation of free-space fluorescence tomography using nuclear imaging

Garofalakis, Anikitos, Dubois, Albertine, Kuhnast, Bertrand, Dupont, Daniel M., Janssens, Isabelle, Mackiewicz, Nicolas, Dollé, Frédéric, Tavitian, Bertrand, Ducongé, Frédéric

Journal:

Year:

2010

Language:

english

File:

PDF, 377 KB

english, 2010

95

The Pyridinyl-6 Position of WAY-100635 as a site for radiofluorination—effect on 5-HT1A receptor radioligand behavior in vivo

Julie A. McCarron, Victor W. Pike, Christer Halldin, Johan Sandell, Judit Sóvágó, Balàsz Gulyas, Zsolt Cselényi, Hakan V. Wikström, Sandrine Marchais-Oberwinkler, Bartek Nowicki, Frédéric Dollé, Lars

Journal:

Molecular Imaging and Biology

Year:

2004

Language:

english

File:

PDF, 325 KB

english, 2004

96

Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons

Haruhiko Kishima, Thomas Poyot, Jocelyne Bloch, Julien Dauguet, Françoise Condé, Frédéric Dollé, Françoise Hinnen, William Pralong, Stéphane Palfi, Nicole Déglon, Patrick Aebischer, Philippe Hantraye

Journal:

Neurobiology of Disease

Year:

2004

Language:

english

File:

PDF, 955 KB

english, 2004

97

Functional Recovery in a Primate Model of Parkinson's Disease following Motor Cortex Stimulation

Xavier Drouot, Satoru Oshino, Bechir Jarraya, Laurent Besret, Haruhiko Kishima, Philippe Remy, Julien Dauguet, Jean Pascal Lefaucheur, Frédéric Dollé, Françoise Condé, Michel Bottlaender, Marc Peschan

Journal:

Year:

2004

Language:

english

File:

PDF, 537 KB

english, 2004

98

Synthesis and radiolabeling of N-[4-[4-(2-[11C]methoxyphenyl)piperazin-1-yl]butyl]benzo[b]thiophene-2-carboxamide — a potential radiotracer for D3 receptor imaging with PET

Bertrand Kuhnast, Héric Valette, Laurent Besret, Stéphane Demphel, Christine Coulon, Michèle Ottaviani, Martine Guillermier, Michel Bottlaender, Frédéric Dollé

Journal:

Nuclear Medicine and Biology

Year:

2006

Language:

english

File:

PDF, 444 KB

english, 2006

99

Whole-body distribution and radiation dosimetry of the dopamine transporter radioligand [11C]PE2I in healthy volunteers

Maria-João Ribeiro, Marcel Ricard, Marie-Angele Lièvre, Sandrine Bourgeois, Patrick Emond, Philippe Gervais, Frédéric Dollé, André Syrota

Journal:

Nuclear Medicine and Biology

Year:

2007

Language:

english

File:

PDF, 189 KB

english, 2007

100

Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling: Part I: PET studies

Wadad Saba, Marie-Anne Peyronneau, Frédéric Dollé, Sébastien Goutal, Michel Bottlaender, Héric Valette

Journal:

Nuclear Medicine and Biology

Year:

2012

Language:

english

File:

PDF, 329 KB

english, 2012

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