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51

PET, MRI, and simultaneous PET/MRI in the development of diagnostic and therapeutic strategies for glioma

Puttick, Simon, Bell, Christopher, Dowson, Nicholas, Rose, Stephen, Fay, Michael

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 3.19 MB

english, 2015

52

Incremental Increase in Fitness Cost with Increased β‐Lactam Resistance in Pneumococci Evaluated by Competition in an Infant Rat Nasal Colonization Model

Trzciński, Krzysztof, Thompson, Claudette M., Gilbey, Andrea M., Dowson, Christopher G., Lipsitch, Marc

Journal:

The Journal of Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 704 KB

english, 2006

53

Novel Corynebacterium diphtheriae in Domestic Cats

Hall, Aron J., Cassiday, Pamela K., Bernard, Kathryn A., Bolt, Frances, Steigerwalt, Arnold G., Bixler, Danae, Pawloski, Lucia C., Whitney, Anne M., Iwaki, Masaaki, Baldwin, Adam, Dowson, Christopher

Journal:

Emerging Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 254 KB

english, 2010

54

Increasing feasibility and utility of 18F-FDOPA PET for the management of glioma

Bell, Christopher, Dowson, Nicholas, Puttick, Simon, Gal, Yaniv, Thomas, Paul, Fay, Mike, Smith, Jye, Rose, Stephen

Journal:

Nuclear Medicine and Biology

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

55

Nod1 Signaling Overcomes Resistance of S. pneumoniae to Opsonophagocytic Killing

Lysenko, Elena S., Clarke, Thomas B., Shchepetov, Mikhail, Ratner, Adam J., Roper, David I., Dowson, Christopher G., Weiser, Jeffrey N.

Journal:

Year:

2007

Language:

english

File:

PDF, 471 KB

english, 2007

56

[ACM Press the Sixth Annual Workshop - Oak Ridge, Tennessee (2010.04.21-2010.04.23)] Proceedings of the Sixth Annual Workshop on Cyber Security and Information Intelligence Research - CSIIRW '10 - An organic model for detecting cyber-events

Oehmen, Christopher, Peterson, Elena, Dowson, Scott

Year:

2010

Language:

english

File:

PDF, 235 KB

english, 2010

57

Homeologous Recombination and Mismatch Repair During Transformation in Streptococcus pneumoniae: Saturation of the Hex Mismatch Repair System

Odile Humbert, Marc Prudhomme, Regine Hakenbeck, Christopher G. Dowson and Jean-Pierre Claverys

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.18 MB

english, 1995

58

Penicillin-Resistant Viridans Streptococci have Obtained Altered Penicillin-Binding Protein Genes from Penicillin-Resistant Strains of Streptococcus pneumoniae

Christopher G. Dowson, Agnes Hutchison, Neil Woodford, Alan P. Johnson, Robert C. George and Brian G. Spratt

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 903 KB

english, 1990

59

Infection With Transmissible Strains of Pseudomonas aeruginosa and Clinical Outcomes in Adults With Cystic Fibrosis

Aaron, Shawn D., Vandemheen, Katherine L., Ramotar, Karam, Giesbrecht-Lewis, Tracy, Tullis, Elizabeth, Freitag, Andreas, Paterson, Nigel, Jackson, Mary, Lougheed, M. Diane, Dowson, Christopher, Kumar,

Journal:

JAMA The Journal of the American Medical Association

Year:

2010

Language:

english

File:

PDF, 391 KB

english, 2010

60

GENERAL NEWS

Christopher Lucas, Brian Knowles, Duncan Dowson and Peter Matthews

Journal:

Year:

1994

Language:

english

File:

PDF, 903 KB

english, 1994

61

Whole-Genome Sequence of Corynebacterium pseudotuberculosis 262 Biovar equi Isolated from Cow Milk

Araújo, Carlos Leonardo de A., Dias, Larissa M., Veras, Adonney A. O., Alves, Jorianne T. C., Cavalcante, Ana Lídia Q., Dowson, Christopher G., Azevedo, Vasco, Ramos, Rommel T. J., Silva, Artur, Carne

Journal:

Genome Announcements

Year:

2016

Language:

english

File:

PDF, 153 KB

english, 2016

62

Patient experience and satisfaction with Onabotulinumtoxin A for refractory overactive bladder

Malde, Sachin, Dowson, Christopher, Fraser, Olivia, Watkins, Jane, Khan, Muhammed S., Dasgupta, Prokar, Sahai, Arun

Journal:

BJU International

Year:

2015

Language:

english

File:

PDF, 154 KB

english, 2015

63

DNA methylation in fibrosis

Dowson, Christopher, O’Reilly, Steven

Journal:

European Journal of Cell Biology

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

64

Federated optimisation of kinetic analysis problems

Dowson, Nicholas, Baker, Charles, Thomas, Paul, Smith, Jye, Puttick, Simon, Bell, Christopher, Salvado, Olivier, Rose, Stephen

Journal:

Medical Image Analysis

Year:

2017

Language:

english

File:

PDF, 4.93 MB

english, 2017

65

Combatting AMR: photoactivatable ruthenium( ii )-isoniazid complex exhibits rapid selective antimycobacterial activity

Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G., Sadler,

Journal:

Chemical Science

Year:

2016

Language:

english

File:

PDF, 934 KB

english, 2016

66

Intercontinental Spread of a Multiresistant Clone of Serotype 23F Streptococcus pneumoniae

Rosario Muñoz, Tracey J. Coffey, Margaret Daniels, Christopher G. Dowson, Gotz Laible, Julio Casal, Regine Hakenbeck, Michael Jacobs, James M. Musser, Brian G. Spratt and Alexander Tomasz

Journal:

The Journal of Infectious Diseases

Year:

1991

Language:

english

File:

PDF, 1.20 MB

english, 1991

67

Innate Immunity in Systemic Sclerosis

Dowson, Christopher, Simpson, Nathan, Duffy, Laura, O’Reilly, Steven

Journal:

Current Rheumatology Reports

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

68

Design and utilisation of protocols to characterise dynamic PET uptake of two tracers using basis pursuit

Bell, Christopher, Puttick, Simon, Rose, Stephen, Smith, Jye, Thomas, Paul, Dowson, Nicholas

Journal:

Physics in Medicine and Biology

Year:

2017

Language:

english

File:

PDF, 2.98 MB

english, 2017

69

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase

Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A., Besra, Gurdyal S.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1016 KB

english, 2016

70

Sequence control as a powerful tool for improving the selectivity of antimicrobial polymers

Kuroki, Agnes, Sangwan, Parveen, Qu, Yue, Peltier, Raoul, Sanchez-Cano, Carlos, Moat, John, Dowson, Christopher G, Williams, Elizabeth G.L., Locock, Katherine E. S., Hartlieb, Matthias, Perrier, Sebas

Journal:

ACS Applied Materials & Interfaces

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

71

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, Fülöp, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 922 KB

english, 2017

72

In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB

Hrast, Martina, Jukič, Marko, Patin, Delphine, Tod, Julie, Dowson, Christopher G, Roper, David I, Barreteau, Hélène, Gobec, Stanislav

Journal:

Chemical Biology & Drug Design

Year:

2018

Language:

english

File:

PDF, 514 KB

english, 2018

73

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA)

Sychantha, David, Jones, Carys S., Little, Dustin J., Moynihan, Patrick J., Robinson, Howard, Galley, Nicola F., Roper, David I., Dowson, Christopher G., Howell, P. Lynne, Clarke, Anthony J., Zhang, G

Journal:

Year:

2017

Language:

english

File:

PDF, 5.80 MB

english, 2017

74

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization

Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma, Roper, David I.

Journal:

The Cell Surface

Year:

2018

Language:

english

File:

PDF, 6.09 MB

english, 2018

75

Structural studies suggest aggregation as one of the modes of action for teixobactin

Öster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G

Journal:

Chemical Science

Year:

2018

Language:

english

File:

PDF, 1.87 MB

english, 2018

76

Profiling Interactions of Vaborbactam with Metallo-β-Lactamases

Langley, Gareth W., Cain, Ricky, Tyrrell, Jonathan M., Hinchliffe, Phillip, Calvopiña, Karina, Tooke, Catherine, Widlake, Emma, Dowson, Christopher G., Spencer, James, Walsh, Timothy R., Schofield, Ch

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

77

Evaluation of a library of FDA-approved drugs for their ability to potentiate antibiotics against multidrug resistant Gram-negative pathogens

Hind, Charlotte K., Dowson, Christopher G., Sutton, J. Mark, Jackson, Thomas, Clifford, Melanie, Garner, R. Colin, Czaplewski, Lloyd

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2019

Language:

english

File:

PDF, 1.28 MB

english, 2019

78

Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities

Massarweh, Ahmad, Bosco, Michael, Chantret, Isabelle, Léger, Thibaut, Jamal, Layla, Roper, David I., Dowson, Christopher G., Busca, Patricia, Bouhss, Ahmed, Gravier-Pelletier, Christine, Moore, Stuart

Journal:

Year:

2019

Language:

english

File:

PDF, 5.77 MB

english, 2019

79

Evaluation of a library of FDA-approved drugs for their ability to potentiate antibiotics against multidrug resistant Gram-negative pathogens

Hind, Charlotte K., Dowson, Christopher G., Sutton, J. Mark, Jackson, Thomas, Clifford, Melanie, Garner, R. Colin, Czaplewski, Lloyd

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2019

File:

PDF, 1.28 MB

2019

80

Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities

Massarweh, Ahmad, Bosco, Michael, Chantret, Isabelle, Léger, Thibaut, Jamal, Layla, Roper, David I., Dowson, Christopher G., Busca, Patricia, Bouhss, Ahmed, Gravier-Pelletier, Christine, Moore, Stuart

Journal:

Year:

2019

File:

PDF, 5.77 MB

2019

81

Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of β-Lactam Target-Mediated Resistance

Bellini, Dom, Koekemoer, Lizbé, Newman, Hector, Dowson, Christopher G.

Journal:

Journal of Molecular Biology

Year:

2019

Language:

english

File:

PDF, 3.65 MB

english, 2019

82

Metal Complexes as a Promising Source for New Antibiotics

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G, Baker, Murray V, Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher Gerard, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour,

Journal:

Chemical Science

Year:

2020

File:

PDF, 1.58 MB

2020

83

Correction: Metal complexes as a promising source for new antibiotics

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray, Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher G., Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed

Journal:

Chemical Science

Year:

2020

File:

PDF, 125 KB

2020

84

Investigating Bacteriophages Targeting the Opportunistic Pathogen Acinetobacter baumannii

Styles, Kathryn M., Thummeepak, Rapee, Leungtongkam, Udomluk, Smith, Sophie E., Christie, Gabrielle S., Millard, Andrew, Moat, John, Dowson, Christopher G., Wellington, Elizabeth M. H., Sitthisak, Sut

Journal:

Year:

2020

File:

PDF, 2.16 MB

2020

85

Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin

Jacques, Laura C., Panagiotou, Stavros, Baltazar, Murielle, Senghore, Madikay, Khandaker, Shadia, Xu, Rong, Bricio-Moreno, Laura, Yang, Marie, Dowson, Christopher G., Everett, Dean B., Neill, Daniel R

Journal:

Nature Communications

Year:

2020

File:

PDF, 2.63 MB

2020