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51

Effect of a novel nicotinic receptor antagonist,N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats

N. M. Neugebauer, Z. Zhang, P. A. Crooks, L. P. Dwoskin, M. T. Bardo

Journal:

Psychopharmacology

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006

52

Age and sex differences in the locomotor effect of repeated methylphenidate in rats classified as high or low novelty responders

T. E Wooters, L. P Dwoskin, M. T Bardo

Journal:

Psychopharmacology

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

53

Effects of nornicotine enantiomers on intravenousS(−)-nicotine self-administration and cardiovascular function in rats

D. J. Stairs, N. M. Neugebauer, X. Wei, C. Boustany, M. Hojahmat, L. A. Cassis, P. A. Crooks, L. P. Dwoskin, M. T. Bardo

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 282 KB

english, 2007

54

The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats

Joshua S. Beckmann, Emily D. Denehy, Guangrong Zheng, Peter A. Crooks, Linda P. Dwoskin, Michael T. Bardo

Journal:

Psychopharmacology

Year:

2012

Language:

english

File:

PDF, 213 KB

english, 2012

55

Nornicotine pretreatment decreases intravenous nicotine self-administration in rats

T.A. Green, S.B. Phillips, P.A. Crooks, L.P. Dwoskin, M.T. Bardo

Journal:

Psychopharmacology

Year:

2000

Language:

english

File:

PDF, 64 KB

english, 2000

56

Acute and chronic effects of nornicotine on locomotor activity in rats: altered response to nicotine

L. P. Dwoskin, Peter A. Crooks, LiHong Teng, Thomas A. Green, Michael T. Bardo

Journal:

Psychopharmacology

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

57

Nornicotine is self-administered intravenously by rats

M. T. Bardo, T. A. Green, P. A. Crooks, L. P. Dwoskin

Journal:

Psychopharmacology

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

58

Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism

Dennis K. Miller, Lincoln H. Wilkins, Michael T. Bardo, Peter A. Crooks, Linda P. Dwoskin

Journal:

Psychopharmacology

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

59

First-principles determination of molecular conformations of indolizidine (−)-235B′ in solution

Fang Zheng, Linda P. Dwoskin, Peter A. Crooks, Chang-Guo Zhan

Journal:

Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta)

Year:

2009

Language:

english

File:

PDF, 344 KB

english, 2009

60

The characterization of a novel rigid nicotine analog with α7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion

Roger L. Papke, Guangrong Zheng, Nicole A. Horenstein, Linda P. Dwoskin, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 227 KB

english, 2005

61

Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands

Guangrong Zheng, Linda P. Dwoskin, Agripina G. Deaciuc, Peter A. Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

62

bis-Azaaromatic quaternary ammonium analogues: ligands for α4β2* and α7* subtypes of neuronal nicotinic receptors

Joshua T Ayers, Linda P Dwoskin, A.Gabriela Deaciuc, Vladimir P Grinevich, Jun Zhu, Peter A Crooks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 139 KB

english, 2002

63

Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression

Jun Zhu, Michael T. Bardo, Ronald C. Bruntz, Dustin J. Stairs, Linda P. Dwoskin

Journal:

European Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 756 KB

english, 2007

64

Pharmacological Evidence for the Existence of Multiple Functional Pools of Brain Serotonin: Analysis of Brain Perfusate From Conscious Rats

Mark S. Kleven, Linda P. Dwoskin, Sheldon B. Sparber

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 660 KB

english, 1983

65

S(-)-Nornicotine Increases Dopamine Release in a Calcium-Dependent Manner from Superfused Rat Striatal Slices

Linda P. Dwoskin, Susan T. Buxton, Ann L. Jewell, Peter A. Crooks

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 886 KB

english, 1993

66

Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex

Jun Zhu, Subbu Apparsundaram, Michael T. Bardo, Linda P. Dwoskin

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 274 KB

english, 2005

67

The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery

Roger L. Papke, Linda P. Dwoskin, Peter A. Crooks

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 555 KB

english, 2007

68

Nicotine increases dopamine clearance in medial prefrontal cortex in rats raised in an enriched environment

Jun Zhu, Michael T. Bardo, Thomas A. Green, Peter J. Wedlund, Linda P. Dwoskin

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 586 KB

english, 2007

69

bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse

Thomas E Wooters, Andrew M Smith, Marharyta Pivavarchyk, Kiran B Siripurapu, J Michael McIntosh, Zhenfa Zhang, Peter A Crooks, Michael T Bardo, Linda P Dwoskin

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

70

Genetics of novelty seeking, amphetamine self-administration and reinstatement using inbred rats

A. C. Meyer, S. Rahman, R. J. Charnigo, L. P. Dwoskin, J. C. Crabbe, M. T. Bardo

Journal:

Genes, Brain and Behavior

Year:

2010

Language:

english

File:

PDF, 854 KB

english, 2010

71

Does Dopamine Contribute to Striatal Damage Caused by Impaired Mitochondrial Function?

WILLIAM F. MARAGOS, REBEKAH J. JAKEL, M. DATHAN CHESNUT, JAMES W. GEDDES, LINDA P. DWOSKIN

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 750 KB

english, 1999

72

Pharmacological similarities between native brain and heterologously expressed α4β2 nicotinic receptors

Navid Shafaee, McCann Houng, Anthony Truong, Nareerat Viseshakul, Antonio Figl, Sumandeep Sandhu, John R Forsayeth, Linda P Dwoskin, Peter A Crooks, Bruce N Cohen

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 256 KB

english, 1999

73

Region-specific effects of N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo

S Rahman, Z Zhang, R L Papke, P A Crooks, L P Dwoskin, M T Bardo

Journal:

British Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 530 KB

english, 2008

74

A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine

Joshua T. Ayers, Rui Xu, Linda P. Dwoskin, Peter A. Crooks

Journal:

The AAPS Journal

Year:

2005

Language:

english

File:

PDF, 203 KB

english, 2005

75

Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the α4β2 nicotinic acetylcholine receptor subtype using nonlinear techniques

Joshua T. Ayers, Aaron Clauset, Jeffrey D. Schmitt, Linda P. Dwoskin, Peter A. Crooks

Journal:

The AAPS Journal

Year:

2005

Language:

english

File:

PDF, 469 KB

english, 2005

76

N-n-alkylnicotinium analogs, a novel class of antagonists at α4β2* Nicotinic acetylcholine receptors: Inhibition of S(-)-nicotine-evoked 86Rb+Efflux from rat thalamic synaptosomes

Lincoln H. Wilkins, Dennis K. Miller, Joshua T. Ayers, Peter A. Crooks, Linda P. Dwoskin

Journal:

The AAPS Journal

Year:

2005

Language:

english

File:

PDF, 257 KB

english, 2005

77

Stereocontrolled Synthesis and Pharmacological Evaluation of cis-2,6-Diphenethyl-1-azabicyclo[2.2.2]octanes as Lobelane Analogues

Zheng, Guangrong, Dwoskin, Linda P., Deaciuc, Agripina G., Crooks, Peter A.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 826 KB

english, 2009

78

Defunctionalized Lobeline Analogues: Structure−Activity of Novel Ligands for the Vesicular Monoamine Transporter

Zheng, Guangrong, Dwoskin, Linda P., Deaciuc, Agripina G., Norrholm, Seth D., Crooks, Peter A.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 181 KB

english, 2005

79

HIV-1 protein Tat inhibits vesicular monoamine transporter-2 activity in rat striatum

Shaji Theodore, Wayne A. Cass, Linda P. Dwoskin, William F. Maragos

Journal:

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

80

DuP 753, a nonpeptide angiotensin II-1 receptor antagonist, alters dopaminergic function in rat striatum

L. P. Dwoskin, A. L. Jewell, L. A. Cassis

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1992

Language:

english

File:

PDF, 838 KB

english, 1992

81

Synthesis and turnover of 3H-5-hydroxytryptamine in the lateral cerebroventricle

K.M. Kantak, M.J. Wayner, H.A. Tilson, L.P. Dwoskin, J.M. Stein

Journal:

Pharmacology Biochemistry and Behavior

Year:

1978

Language:

english

File:

PDF, 645 KB

english, 1978

82

Studies on the specificity of neurochemical and behavioral effects of LSD-25

S.B. Sparber, L.P. Dwoskin, M.S. Kleven

Journal:

Pharmacology Biochemistry and Behavior

Year:

1986

Language:

english

File:

PDF, 504 KB

english, 1986

83

Evidence for antiserotonergic properties of yohimbine

Linda P. Dwoskin, Bethany S. Neal, Sheldon B. Sparber

Journal:

Pharmacology Biochemistry and Behavior

Year:

1988

Language:

english

File:

PDF, 578 KB

english, 1988

84

Environmental enrichment attenuates locomotor sensitization, but not in vitro dopamine release, induced by amphetamine

M.T Bardo, S.L Bowling, J.K Rowlett, P Manderscheid, S.T Buxton, L.P Dwoskin

Journal:

Pharmacology Biochemistry and Behavior

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

85

Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD)

Linda P. Dwoskin, B. Matthew Joyce, Guangrong Zheng, Nichole M. Neugebauer, Vamshi K. Manda, Paul Lockman, Roger L. Papke, Michael T. Bardo, Peter A. Crooks

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 680 KB

english, 2007

86

Nicotinic receptor-based therapeutics and candidates for smoking cessation

Linda P. Dwoskin, Andrew M. Smith, Thomas E. Wooters, Zhenfa Zhang, Peter A. Crooks, Michael T. Bardo

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 269 KB

english, 2009

87

GZ556A and ZZ204G are novel small molecule antagonists of α9α10 nAChRs and are analgesic in rats

J.M. McIntosh, L.P. Dwoskin, P.A. Crooks, J.R. Holtman Jr.

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 58 KB

english, 2009

88

The novel nicotinic receptor antagonist, N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [3H]norepinephrine overflow from rat hippocampal slices

Andrew M. Smith, Gurpreet K. Dhawan, Zhenfa Zhang, Kiran B. Siripurapu, Peter A. Crooks, Linda P. Dwoskin

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 251 KB

english, 2009

89

Repeated nicotine administration robustly increases bPiDDB inhibitory potency at α6β2-containing nicotinic receptors mediating nicotine-evoked dopamine release

Andrew M. Smith, Marharyta Pivavarchyk, Thomas E. Wooters, Zhenfa Zhang, Guangrong Zheng, J. Michael McIntosh, Peter A. Crooks, Michael T. Bardo, Linda P. Dwoskin

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

90

Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine

Nichole M. Neugebauer, S. Tiffany Cunningham, Jun Zhu, Rachel I. Bryant, Lisa S. Middleton, Linda P. Dwoskin

Journal:

Developmental Brain Research

Year:

2004

Language:

english

File:

PDF, 345 KB

english, 2004

91

Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism

Lisa S. Middleton, Subbu Apparsundaram, Kelley A. King-Pospisil, Linda P. Dwoskin

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 337 KB

english, 2007

92

The novel nicotinic receptor antagonist N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens

Shafiqur Rahman, Nichole M. Neugebauer, Zhenfa Zhang, Peter A. Crooks, Linda P. Dwoskin, Michael T. Bardo

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

93

Indolizidine (−)-235B′ and related structural analogs: Discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release

Marharyta Pivavarchyk, Andrew M. Smith, Zhenfa Zhang, Dejun Zhou, Xu Wang, Naoki Toyooka, Hiroshi Tsuneki, Toshiyasu Sasaoka, J. Michael McIntosh, Peter A. Crooks, Linda P. Dwoskin

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 772 KB

english, 2011

94

The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic

Joseph R. Holtman, Linda P. Dwoskin, Cheryl Dowell, Elzbieta P. Wala, Zhenfa Zhang, Peter A. Crooks, J. Michael McIntosh

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 834 KB

english, 2011

95

Lobeline produces conditioned taste avoidance in rats

S.B Harrod, L.P Dwoskin, M.T Bardo

Journal:

Pharmacology Biochemistry and Behavior

Year:

2004

Language:

english

File:

PDF, 196 KB

english, 2004

96

Mecamylamine, dihydro-β-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine

Amanda M. Struthers, Jamie L. Wilkinson, Linda P. Dwoskin, Peter A. Crooks, Rick A. Bevins

Journal:

Pharmacology Biochemistry and Behavior

Year:

2009

Language:

english

File:

PDF, 476 KB

english, 2009

97

Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices

Thomas A Green, Peter A Crooks, Michael T Bardo, Linda P Dwoskin

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 124 KB

english, 2001

98

A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse

Linda P. Dwoskin, Peter A. Crooks

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

99

Mitochondrial toxin inhibition of [3H]dopamine uptake into rat striatal synaptosomes

William F. Maragos, Jun Zhu, M.Dathan Chesnut, Linda P. Dwoskin

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 141 KB

english, 2002

100

Nornicotine, a nicotine metabolite and tobacco alkaloid: desensitization of nicotinic receptor-stimulated dopamine release from rat striatum

Linda P. Dwoskin, Li Hong Teng, Peter A. Crooks

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 147 KB

english, 2001