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51

Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products

Regina Appiah-Opong, Jan N.M. Commandeur, Barbara van Vugt-Lussenburg, Nico P.E. Vermeulen

Journal:

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

52

Impact of individual-donation nucleic acid testing on risk of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus transmission by blood transfusion in South Africa

Marion Vermeulen, Nico Lelie, Wendy Sykes, Robert Crookes, Johanna Swanevelder, Lilian Gaggia, Martin Le Roux, Eben Kuun, Sam Gulube, Ravi Reddy

Journal:

Transfusion (Wiley)

Year:

2009

Language:

english

File:

PDF, 265 KB

english, 2009

53

Refinement of a viral transmission risk model for blood donations in seroconversion window phase screened by nucleic acid testing in different pool sizes and repeat test algorithms

Jos Weusten, Marion Vermeulen, Harry van Drimmelen, Nico Lelie

Journal:

Transfusion (Wiley)

Year:

2011

Language:

english

File:

PDF, 446 KB

english, 2011

54

Ab initio calculations on iron-porphyrin model systems for intermediates in the oxidative cycle of cytochrome P450s

Marcel J. de Groot, Remco W.A. Havenith, H. Maarten Vinkers, Renate Zwaans, Nico P.E. Vermeulen, Joop H. van Lenthe

Journal:

Journal of Computer-Aided Molecular Design

Year:

1998

Language:

english

File:

PDF, 90 KB

english, 1998

55

Design, Synthesis, and Characterization of 7-Methoxy-4-(aminomethyl)coumarin as a Novel and Selective Cytochrome P450 2D6 Substrate Suitable for High-Throughput Screening

Onderwater, Rob C. A., Venhorst, Jennifer, Commandeur, Jan N. M., Vermeulen, Nico P. E.

Journal:

Chemical Research in Toxicology

Year:

1999

Language:

english

File:

PDF, 64 KB

english, 1999

56

Combining substrate dynamics, binding statistics, and energy barriers to rationalize regioselective hydroxylation of octane and lauric acid by CYP102A1 and mutants

K. Anton Feenstra, Eugene B. Starikov, Vlada B. Urlacher, Jan N.M. Commandeur, Nico P.E. Vermeulen

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 553 KB

english, 2007

57

Free Energy Calculations Give Insight into the Stereoselective Hydroxylation of α-Ionones by Engineered Cytochrome P450 BM3 Mutants

de Beer, Stephanie B.A., Venkataraman, Harini, Geerke, Daan P., Oostenbrink, Chris, Vermeulen, Nico P.E.

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 1.72 MB

english, 2012

58

Surface-Enhanced Resonance Raman Scattering of Cytochrome P450-2D6 on Coated Silver Hydrosols

Bonifacio, Alois, Keizers, Peter H. J., Vermeulen, Nico P. E., Commandeur, Jan N. M., Gooijer, Cees, van der Zwan, Gert

Journal:

Year:

2007

Language:

english

File:

PDF, 301 KB

english, 2007

59

Virtual Screening and Prediction of Site of Metabolism for Cytochrome P450 1A2 Ligands

Vasanthanathan, Poongavanam, Hritz, Jozef, Taboureau, Olivier, Olsen, Lars, Steen Jørgensen, Flemming, Vermeulen, Nico P. E., Oostenbrink, Chris

Journal:

Journal of Chemical Information and Modeling

Year:

2009

Language:

english

File:

PDF, 1.68 MB

english, 2009

60

Identification of CYP1A2 ligands by structure-based and ligand-based virtual screening

Lastdrager, Jeroen, Oostenbrink, Chris, Vasanthanathan, Poongavanam, Commandeur, Jan N. M., Vermeulen, Nico P. E., Jørgensen, Flemming S., Olsen, Lars

Journal:

Year:

2011

Language:

english

File:

PDF, 517 KB

english, 2011

61

Bioaccumulation, biotransformation and DNA binding of pahs in feral eel (Anguilla anguilla) exposed to polluted sediments: A field survey

Ron van der Oost, Henk Heida, Karel Satumalay, Frederik-Jan van Schooten, Freek Ariese, Nico P. E. Vermeulen

Journal:

Environmental Toxicology and Chemistry

Year:

1994

Language:

english

File:

PDF, 1.12 MB

english, 1994

62

Comparative Cytotoxicity of 14 Novel Selenocysteine Se-Conjugates in Rat Renal Proximal Tubular Cells

Ioanna Andreadou, Bob van de Water, Jan N.M. Commandeur, Fred J. Nagelkerke, Nico P.E. Vermeulen

Journal:

Toxicology and Applied Pharmacology

Year:

1996

Language:

english

File:

PDF, 202 KB

english, 1996

63

The Use of Humanin VitroMetabolic Parameters to Explore the Risk Assessment of Hazardous Compounds: The Case of Ethylene Dibromide

Jan-Peter H.T.M. Ploemen, Lars W. Wormhoudt, Guido R.M.M. Haenen, Martin J. Oudshoorn, Jan N.M. Commandeur, Nico P.E. Vermeulen, Isabelle de Waziers, Philippe H. Beaune, Tadashi Watabe, Peter J. van B

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 297 KB

english, 1997

64

Evaluation of Urinary Biomarkers for Radical-Induced Liver Damage in Rats Treated with Carbon Tetrachloride

Loeckie L. de Zwart, Ralph C.A. Hermanns, John H.N. Meerman, Jan N.M. Commandeur, Paul J.M. Salemink, Nico P.E. Vermeulen

Journal:

Toxicology and Applied Pharmacology

Year:

1998

Language:

english

File:

PDF, 242 KB

english, 1998

65

A new approach to firm evaluation

Erik M. Vermeulen, Jaap Spronk, Nico van der Wijst

Journal:

Annals of Operations Research

Year:

1993

Language:

english

File:

PDF, 1.07 MB

english, 1993

66

Cytochrome P-450-mediated oxidation of substrates by electron-transfer; Role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol

Ronald van de Straat, Robert M. Vromans, Patrick Bosman, John de Vries, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1988

Language:

english

File:

PDF, 771 KB

english, 1988

67

Effect of thiols on lipid peroxidation in rat liver microsomes

Guido R.M.M. Haenen, Nico P.E. Vermeulen, Henk Timmerman, Aalt Bast

Journal:

Chemico-Biological Interactions

Year:

1989

Language:

english

File:

PDF, 682 KB

english, 1989

68

Reductase and oxidase activity of rat liver cytochrome P450 with 2,3,5,6-tetramethylbenzoquinone as substrate

Arnold R. Goeptar, Johan M. Te Koppele, Etienne P.A. Neve, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1992

Language:

english

File:

PDF, 1.20 MB

english, 1992

69

The cytotoxicity of mitomycin C and Adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes

Arnold R. Goeptar, Johan M. te Koppele, Hansruedi R. Glatt, Ed J. Groot, Albrecht Seidel, Martine Barrenscheen, Catherine Wölfel, Johannes Doehmer, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1995

Language:

english

File:

PDF, 1.53 MB

english, 1995

70

Cytochrome P450 catalyzed metabolism of 1,2-dibromoethane in liver microsomes of differentially induced rats

Lars W. Wormhoudt, Jan H.T.M. Ploemen, Jan N.M. Commandeur, Ben van^Ommen, Peter J. van Bladeren, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1996

Language:

english

File:

PDF, 903 KB

english, 1996

71

Inter-individual variability in the oxidation of 1,2-dibromoethane: use of heterologously expressed human cytochrome P450 and human liver microsomes

Lars W. Wormhoudt, Jan H.T.M. Ploemen, Isabelle de Waziers, Jan N.M. Commandeur, Philippe H. Beaune, Peter J. van Bladeren, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1996

Language:

english

File:

PDF, 1.26 MB

english, 1996

72

Interrelationships between bioaccumulation of organic trace pollutants (PCBs, organochlorine pesticides and PAHs), and MFO-induction in fish

Ron Van der Oost, Henk Heida, Antoon Opperhuizen, Nico P.E. Vermeulen

Journal:

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Year:

1991

Language:

english

File:

PDF, 544 KB

english, 1991

73

Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolism

Peter H.J. Keizers, Barbara M.A. Lussenburg, Chris de Graaf, Letty M. Mentink, Nico P.E. Vermeulen, Jan N.M. Commandeur

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 253 KB

english, 2004

74

The role of phenylalanine 483 in cytochrome P450 2D6 is strongly substrate dependent

Barbara M.A. Lussenburg, Peter H.J. Keizers, Chris de Graaf, Mats Hidestrand, M. Ingelman-Sundberg, Nico P.E. Vermeulen, Jan N.M. Commandeur

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 245 KB

english, 2005

75

Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites

Micaela C. Damsten, Barbara M.A. van Vugt-Lussenburg, Tineke Zeldenthuis, Jon S.B. de Vlieger, Jan N.M. Commandeur, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

76

Interactions of organophosphates with keratins in the cornified epithelium of human skin

Daan R.W. Verstappen, Albert G. Hulst, Alex Fidder, Nico P.E. Vermeulen, Daan Noort

Journal:

Chemico-Biological Interactions

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

77

Relevance of hair and spines of the European hedgehog (Erinaceus europaeus) as biomonitoring tissues for arsenic and metals in relation to blood

Frouke Vermeulen, Helga D'Havé, Valentine K. Mubiana, Nico W. Van den Brink, Ronny Blust, Lieven Bervoets, Wim De Coen

Journal:

Science of The Total Environment

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

78

Selective induction of cytochrome P450 3A1 by dexamethasone in cultured rat hepatocytes: Analysis with a novel reverse transcriptase–polymerase chain reaction assay

Peter A.Chr. ’t Hoen, Jan N.M Commandeur, Nico P.E Vermeulen, Theo J.C Van Berkel, Martin K Bijsterbosch

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 422 KB

english, 2000

79

Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugates

Peter A.C. ’t Hoen, Martijn Rooseboom, Martin K. Bijsterbosch, Theo J.C. van Berkel, Nico P.E. Vermeulen, Jan N.M. Commandeur

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 155 KB

english, 2002

80

Tissue distribution of cytosolic β-elimination reactions of selenocysteine Se-conjugates in rat and human

Martijn Rooseboom, Nico P.E. Vermeulen, Ed J. Groot, Jan N.M. Commandeur

Journal:

Chemico-Biological Interactions

Year:

2002

Language:

english

File:

PDF, 533 KB

english, 2002

81

Urinary excretion of biomarkers for radical-induced damage in rats treated with NDMA or diquat and the effects of calcium carbimide co-administration

Loeckie L de Zwart, Nico P.E Vermeulen, Ralph C.A Hermanns, Jan N.M Commandeur, Paul J.M Salemink, John H.N Meerman

Journal:

Chemico-Biological Interactions

Year:

1999

Language:

english

File:

PDF, 345 KB

english, 1999

82

Biomarkers of free radical damage: Applications in experimental animals and in humans

Loeckie L de Zwart, John H.N Meerman, Jan N.M Commandeur, Nico P.E Vermeulen

Journal:

Free Radical Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 276 KB

english, 1999

83

Evaluation of a novel high-throughput assay for cytochrome P450 2D6 using 7-methoxy-4-(aminomethyl)-coumarin

Jennifer Venhorst, Rob C.A Onderwater, John H.N Meerman, Nico P.E Vermeulen, Jan N.M Commandeur

Journal:

European Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

84

Mass Spectrometric Characterization of Protein Adducts of Multiple P450-Dependent Reactive Intermediates of Diclofenac to Human Glutathione- S -transferase P1-1

Boerma, Jan Simon, Dragovic, Sanja, Vermeulen, Nico P. E., Commandeur, Jan N. M.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

85

Cytochrome P450 in Silico: An Integrative Modeling Approach

de Graaf, Chris, Vermeulen, Nico P. E., Feenstra, K. Anton

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 1.19 MB

english, 2005

86

Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver

S. Oetari, M. Sudibyo, Jan N.M. Commandeur, R. Samhoedi, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 785 KB

english, 1996

87

Biomonitoring of aquatic pollution with feral eel (Anguilla anguilla) II. Biomarkers: pollution-induced biochemical responses

Ron van der Oost, Anders Goksøyr, Malin Celander, Henk Heida, Nico P.E. Vermeulen

Journal:

Aquatic Toxicology

Year:

1996

Language:

english

File:

PDF, 2.69 MB

english, 1996

88

The Use of Macroporous Microcarriers for the Large-Scale Growth of V79 Cells Genetically Designed to Express Single Human Cytochrome P450 Isoenzymes and for the Characterization of the Expressed Cytochrome P450

Rob C.A. Onderwater, Arnold R. Goeptar, Piet R. Levering, Ria M.E. Vos, Pierre N.M. Konings, Johannes Doehmer, Jan N.M. Commandeur, Nico P.E. Vermeulen

Journal:

Protein Expression and Purification

Year:

1996

Language:

english

File:

PDF, 161 KB

english, 1996

89

4-Hydroxy-2,3-trans-nonenal stimulates microsomal lipid peroxidation by reducing the glutathione-dependent protection

Guido R.M.M. Haenen, Jacintha N.L. Tai Tin Tsoi, Nico P.E. Vermeulen, Henk Timmerman, Aalt Bast

Journal:

Archives of Biochemistry and Biophysics

Year:

1987

Language:

english

File:

PDF, 628 KB

english, 1987

90

Activation of the microsomal glutathione S-transferase by metabolites of α-methyldopa

Guido R.M.M. Haenen, Frank P. Jansen, Nico P.E. Vermeulen, Aalt Bast

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 584 KB

english, 1991

91

Activation of the microsomal glutathione-s-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acrolein

Guido R.M.M. Haenen, Nico P.E. Vermeulen, Jacintha N.L. Tai Tin Tsoi, Henri M.N. Ragetli, Henk Timmerman, Aalt Bast

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 716 KB

english, 1988

92

Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney: Uptake of the conjugates and activation to toxic metabolites

Pieter J. Boogaard, Jan N.M. Commandeur, Gerard J. Mulder, Nico P.E. Vermeulen, J.Fred Nagelkerke

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 936 KB

english, 1989

93

Cytotoxic and cytoprotective activities of curcumin: Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes

Imono Argo Donatus, Sardjoko, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 759 KB

english, 1990

94

The mechanism of interaction between cisplatin and selenite

Glenn S. Baldew, Johannes G.J. Mol, Frans J.J. de Kanter, Ben Van Baar, Jeroen J.M. de Goeij, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 838 KB

english, 1991

95

Metabolism of l-cysteine S-conjugates and N-(trideuteroacetyl)-l-cysteineS-conjugates of four fluoroethylenes in the rat: Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids

Jan.N.M. Commandeur, Gerard J. Stijntjes, Janet Wijngaard, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 830 KB

english, 1991

96

The influence of ebselen on the toxicity of cisplatin in LLC-PK1 cells

Glenn S. Baldew, Antonius P. Boymans, Johannes G.J. Mol, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 748 KB

english, 1992

97

One-electron reductive bioactivation of 2,3,5,6-tetramethylbenzoquinone by cytochrome P450

Arnold R. Goeptar, Johan M. te Koppele, Jan M.S. van Maanen, Clema E.M. Zoetemelk, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.10 MB

english, 1992

98

The role of lipid peroxidation in the nephrotoxicity of cisplatin

Nico P.E. Vermeulen, Glenn S. Baldew

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 811 KB

english, 1992

99

Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes

Li Qiu-Ju, Jos G.M. Bessems, Jan N.M. Commandeur, Bas Adams, Nico P.E. Vermeulen

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.43 MB

english, 1994

100

In vitro inhibition of rat and human glutathione S-transferase isoenzymes by disulfiram and diethyldithiocarbamate

Jan-Peter H.T.M. Ploemen, Marlou L.P.S. van Iersel, Lars W. Wormhoudt, Jan N.M. Commandeur, Nico P.E. Vermeulen, Peter J. van Bladeren

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 900 KB

english, 1996