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51

Viral kinetics of combination pegylated interferon a-2a and ribavirin in patients with hepatitis C cirrhosis

Edward Gane, Bruce Chapman, Joanne Holland, Janice Duxfield, Gan Shi, Dale Cornelius, Heather Bain

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 109 KB

english, 2002

52

The clinical diversity and role of chemotherapy in lymphoproliferative disorder in liver transplant recipients

Michelle McCarthy, John Ramage, Alistair McNair, Edward Gane, Bernard Portmann, Anthony Pagliuca, Mohamed Rela, Nigel Heaton, Ghulam J. Mufti, Roger Williams

Journal:

Journal of Hepatology

Year:

1997

Language:

english

File:

PDF, 814 KB

english, 1997

53

Massive ascitic fluid loss and coagulation disturbances after liver transplantation

Edward Gane, Peter Langley, Roger Williams

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 789 KB

english, 1995

54

Selection pressure on the hepatitis B virus pre-S/S and P open reading frames in Tongan subjects with a chronic hepatitis B virus infection

William G.H. Abbott, Peter Tsai, Howard A. Ross, Malakai ‘Ofanoa, Alexander J. Trevarton, John Hornell, Stephen R. Munn, Edward J. Gane

Journal:

Antiviral Research

Year:

2012

Language:

english

File:

PDF, 375 KB

english, 2012

55

106 International, multicenter, randomized, controlled study for the treatment of patients with chronic hepatitis C and persistently normal ALT levels with peginterferon alfa-2A (40KD) (PEGASYS®) and ribavirin (copegus®)

Stefan Zeuzem, Moisés Diago, Edward Gane, Rajender Reddy, Paul Pockros, Patrizia Farci, Norman Lardelli, Mitchell Shiffman

Journal:

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

56

Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levels

Stefan Zeuzem, Moisés Diago, Edward Gane, K. Rajender Reddy, Paul Pockros, Daniele Prati, Mitchell Shiffman, Patrizia Farci, Norman Gitlin, Christopher B. O’Brien, François Lamour, Pilar Lardelli

Journal:

Gastroenterology

Year:

2004

Language:

english

File:

PDF, 194 KB

english, 2004

57

Lamivudine Plus Low-Dose Hepatitis B Immunoglobulin to Prevent Recurrent Hepatitis B Following Liver Transplantation

Edward J. Gane, Peter W. Angus, Simone Strasser, Darrell H.G. Crawford, John Ring, Gary P. Jeffrey, Geoffrey W. McCaughan

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 294 KB

english, 2007

58

2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B

Yun–Fan Liaw, Edward Gane, Nancy Leung, Stefan Zeuzem, Yuming Wang, Ching Lung Lai, E. Jenny Heathcote, Michael Manns, Natalie Bzowej, Junqi Niu, Steven–Huy Han, Seong Gyu Hwang, Yilmaz Cakaloglu, Myr

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

59

Three-Year Efficacy and Safety of Tenofovir Disoproxil Fumarate Treatment for Chronic Hepatitis B

E. Jenny Heathcote, Patrick Marcellin, Maria Buti, Edward Gane, Robert A. De Man, Zahary Krastev, George Germanidis, Samuel S. Lee, Robert Flisiak, Kelly Kaita, Michael Manns, Iskren Kotzev, Konstanti

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

60

Effect of IL28B Genotype on Early Viral Kinetics During Interferon-Free Treatment of Patients With Chronic Hepatitis C

Tom W. Chu, Rohit Kulkarni, Edward J. Gane, Stuart K. Roberts, Catherine Stedman, Peter W. Angus, Brett Ritchie, Xiao-Yu Lu, David Ipe, Uri Lopatin, Soren Germer, Victor A. Iglesias, Robert Elston, Pa

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 758 KB

english, 2012

61

Nucleotide Polymerase Inhibitor Sofosbuvir plus Ribavirin for Hepatitis C

Gane, Edward J., Stedman, Catherine A., Hyland, Robert H., Ding, Xiao, Svarovskaia, Evguenia, Symonds, William T., Hindes, Robert G., Berrey, M. Michelle

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 594 KB

english, 2013

62

Peginterferon Alfa-2a in Patients with Chronic Hepatitis C

Zeuzem, Stefan, Feinman, S. Victor, Rasenack, Jens, Heathcote, E. Jenny, Lai, Ming-Yang, Gane, Edward, O'Grady, John, Reichen, Jürg, Diago, Moises, Lin, Amy, Hoffman, Joseph, Brunda, Michael J.

Journal:

Boston Medical and Surgical Journal

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

63

Telbivudine Improves Renal Function in Patients With Chronic Hepatitis B

Gane, Edward J., Deray, Gilbert, Liaw, Yun-Fan, Lim, Seng Gee, Lai, Ching-Lung, Rasenack, Jens, Wang, Yuming, Papatheodoridis, George, Di Bisceglie, Adrian, Buti, Maria, Samuel, Didier, Uddin, Alkaz,

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 280 KB

english, 2014

64

Simeprevir Increases Rate of Sustained Virologic Response Among Treatment-Experienced Patients With HCV Genotype-1 Infection: A Phase IIb Trial

Zeuzem, Stefan, Berg, Thomas, Gane, Edward, Ferenci, Peter, Foster, Graham R., Fried, Michael W., Hezode, Christophe, Hirschfield, Gideon M., Jacobson, Ira, Nikitin, Igor, Pockros, Paul J., Poordad, F

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

65

Efficacy of Nucleotide Polymerase Inhibitor Sofosbuvir Plus the NS5A Inhibitor Ledipasvir or the NS5B Non-Nucleoside Inhibitor GS-9669 Against HCV Genotype 1 Infection

Gane, Edward J., Stedman, Catherine A., Hyland, Robert H., Ding, Xiao, Svarovskaia, Evguenia, Subramanian, G. Mani, Symonds, William T., McHutchison, John G., Pang, Phillip S.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 585 KB

english, 2014

66

Current Challenges in Bioequivalence, Quality, and Novel Assessment Technologies for Topical Products

Yacobi, Avraham, Shah, Vinod P., Bashaw, Edward D., Benfeldt, Eva, Davit, Barbara, Ganes, Derek, Ghosh, Tapash, Kanfer, Isadore, Kasting, Gerald B., Katz, Lindsey, Lionberger, Robert, Lu, Guang Wei, M

Journal:

Pharmaceutical Research

Year:

2014

Language:

english

File:

PDF, 255 KB

english, 2014

67

Effects of Sofosbuvir-Based Treatment, With and Without Interferon, on Outcome and Productivity of Patients With Chronic Hepatitis C

Younossi, Zobair M., Stepanova, Maria, Henry, Linda, Gane, Edward, Jacobson, Ira M., Lawitz, Eric, Nelson, David, Gerber, Lynn, Nader, Fatema, Hunt, Sharon

Journal:

Clinical Gastroenterology and Hepatology

Year:

2014

Language:

english

File:

PDF, 937 KB

english, 2014

68

Minimal impact of sofosbuvir and ribavirin on health related quality of life in Chronic Hepatitis C (CH-C)

Younossi, Zobair M., Stepanova, Maria, Henry, Linda, Gane, Edward, Jacobson, Ira M., Lawitz, Eric, Nelson, David, Nader, Fatema, Hunt, Sharon

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 730 KB

english, 2014

69

A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment

Lawitz, Eric, Rodriguez-Torres, Maribel, Stoehr, Albrecht, Gane, Edward J., Serfaty, Lawrence, Bhanja, Sanhita, Barnard, Richard J., An, Di, Gress, Jacqueline, Hwang, Peggy, Mobashery, Niloufar

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 698 KB

english, 2013

70

869b Simeprevir (TMC435) With Peginterferon/Ribavirin for Treatment of Chronic HCV Genotype 1 Infection in Patients Who Relapsed After Previous Interferon-Based Therapy: Results From PROMISE, a Phase III Trial

Lawitz, Eric, Forns, Xavier, Zeuzem, Stefan, Gane, Edward, Bronowicki, Jean-Pierre, Andreone, Pietro, Horban, Andrzej, Brown, Ashley, Peeters, Monika, Lenz, Oliver, Ouwerkerk-Mahadevan, Sivi, Kalmeije

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 231 KB

english, 2013

71

Sa1029 An Analysis of Response Rates by Fibrosis Stage in Patients Treated With Faldaprevir, Bi 207127 and Ribavirin in the Sound-C2 Study

Asselah, Tarik, Zeuzem, Stefan, Soriano, Vicente, Bronowicki, Jean-Pierre, Lohse, Ansgar W., Müllhaupt, Beat, Schuchmann, Marcus, Bourliere, Marc, Buti, Maria, Roberts, Stuart K., Gane, Edward, Stern,

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 253 KB

english, 2013

72

238 Sofosbuvir/Ledipasvir Fixed Dose Combination Is Safe and Effective in HCV Infected Populations Including Decompensated Patients and Patients With Prior Sofosbuvir Treatment Experience

Gane, Edward, Hyland, Rob H., Pang, Phil, Symonds, William T., McHutchison, John G., Stedman, Catherine A.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 703 KB

english, 2014

73

P672 HBeAg LEVELS DIFFER ACCORDING TO HBV GENOTYPE IN IMMUNE CLEARANCE DISEASE

Bayliss, J., Thompson, A., Rosenberg, G., Gaggar, A., Kitrinos, K., Gane, E., Chan, H.L., Li, X., Littlejohn, M., Yuen, L., Edwards, R., Jackson, K., Bonanzinga, S., Hammond, R., Bowden, S., Locarnini

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 69 KB

english, 2014

74

Combination of Vaniprevir With Peginterferon and Ribavirin Significantly Increases the Rate of SVR in Treatment-Experienced Patients With Chronic HCV Genotype 1 Infection and Cirrhosis

Rodriguez–Torres, Maribel, Stoehr, Albrecht, Gane, Edward J., Serfaty, Lawrence, Lawitz, Eric, Zhou, Amy, Bourque, Michael, Bhanja, Sanhita, Strizki, Julie, Barnard, Richard J.O., Hwang, Peggy M.T., D

Journal:

Clinical Gastroenterology and Hepatology

Year:

2014

Language:

english

File:

PDF, 656 KB

english, 2014

75

Oral β-blockade in relation to energy expenditure in clinically stable patients with liver cirrhosis: A double-blind randomized cross-over trial

Lee, Wai Gin, McCall, John L., Gane, Edward J., Murphy, Rinki, Plank, Lindsay D.

Journal:

Year:

2012

Language:

english

File:

PDF, 245 KB

english, 2012

76

Report of an International Workshop: Roadmap for Management of Patients Receiving Oral Therapy for Chronic Hepatitis B

Keeffe, Emmet B., Zeuzem, Stefan, Koff, Raymond S., Dieterich, Douglas T., Esteban–Mur, Rafael, Gane, Edward J., Jacobson, Ira M., Lim, Seng G., Naoumov, Nikolai, Marcellin, Patrick

Journal:

Clinical Gastroenterology and Hepatology

Year:

2007

Language:

english

File:

PDF, 346 KB

english, 2007

77

Accuracy of radiology in detection of hepatocellular carcinoma before liver transplantation

Rizzi, Paolo M., Kane, Pauline A., Ryder, Stephen D., Ramage, John K., Gane, Edward, Tan, Kai C., Portmann, Bernard, Karani, John, Williams, Roger

Journal:

Gastroenterology

Year:

1994

Language:

english

File:

PDF, 457 KB

english, 1994

78

Multiple-Complete-Digest Restriction Fragment Mapping: Generating Sequence-Ready Maps for Large-Scale DNA Sequencing

Gane K.-S. Wong, Jun Yu, Edward C. Thayer and Maynard V. Olson

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.47 MB

english, 1997

79

Serological and clinical outcomes of horizontally transmitted chronic hepatitis B infection in New Zealand Māori: results from a 28-year follow-up study

Lim, Tien Huey, Gane, Edward, Moyes, Chris, Borman, Barry, Cunningham, Chris

Journal:

Year:

2015

Language:

english

File:

PDF, 483 KB

english, 2015

80

Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B

Lau, George K.K., Piratvisuth, Teerha, Luo, Kang Xian, Marcellin, Patrick, Thongsawat, Satawat, Cooksley, Graham, Gane, Edward, Fried, Michael W., Chow, Wan Cheng, Paik, Seung Woon, Chang, Wen Yu, Ber

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

81

Mericitabine and ritonavir-boosted danoprevir with or without ribavirin in treatment-naive HCV genotype 1 patients: INFORM-SVR study

Gane, Edward J., Pockros, Paul J., Zeuzem, Stefan, Marcellin, Patrick, Shikhman, Anna, Bernaards, Coen, Zhou, Julian, Yetzer, Ellen S., Ballester, Rosa, Dwyer, Cindy, Tong, Xiao, Nájera, Isabel, Berta

Journal:

Liver International

Year:

2015

Language:

english

File:

PDF, 505 KB

english, 2015

82

Concordance of sustained virological response 4, 12, and 24 weeks post-treatment with sofosbuvir-containing regimens for hepatitis C virus

Yoshida, Eric M., Sulkowski, Mark S., Gane, Edward J., Herring, Robert W., Ratziu, Vlad, Ding, Xiao, Wang, Jing, Chuang, Shu-Min, Ma, Julie, McNally, John, Stamm, Luisa M., Brainard, Diana M., Symonds

Journal:

Year:

2015

Language:

english

File:

PDF, 987 KB

english, 2015

83

Evaluation of HBV DNA decay kinetics in patients containing both rtM204V/I mutant and wild-type HBV subpopulations during tenofovir DF (TDF) monotherapy or combination therapy with emtricitabine (FTC)/TDF

Liu, Yang, Fung, Scott, Gane, Edward J., Dinh, Phillip, Flaherty, John F., Svarovskaia, Evguenia S., Miller, Michael D., Kitrinos, Kathryn M.

Journal:

Journal of Medical Virology

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

84

No Resistance to Tenofovir Disoproxil Fumarate Through 96 Weeks of Treatment in Patients With Lamivudine-Resistant Chronic Hepatitis B

Corsa, Amoreena C., Liu, Yang, Flaherty, John F., Mitchell, Ben, Fung, Scott K., Gane, Edward, Miller, Michael D., Kitrinos, Kathryn M.

Journal:

Clinical Gastroenterology and Hepatology

Year:

2014

Language:

english

File:

PDF, 838 KB

english, 2014

85

Additive effect of pretransplant obesity, diabetes, and cardiovascular risk factors on outcomes after liver transplantation

Dare, Anna J., Plank, Lindsay D., Phillips, Anthony R. J., Gane, Edward J., Harrison, Barry, Orr, David, Jiang, Yannan, Bartlett, Adam S. J. R.

Journal:

Liver Transplantation

Year:

2014

Language:

english

File:

PDF, 148 KB

english, 2014

86

Type 2 diabetes: A risk factor for liver mortality and complications in hepatitis B cirrhosis patients

Hsiang, John C, Gane, Edward J, Bai, Wayne W, Gerred, Stephen J

Journal:

Journal of Gastroenterology and Hepatology

Year:

2015

Language:

english

File:

PDF, 969 KB

english, 2015

87

Air travel with limbs immobilised in casts

Zeiton, Moez, Gane, Angus, Jain, Neil, Holt, Edward Martin

Journal:

International Journal of Surgery

Year:

2014

Language:

english

File:

PDF, 51 KB

english, 2014

88

Telbivudine plus pegylated interferon alfa-2a in a randomized study in chronic hepatitis B is associated with an unexpected high rate of peripheral neuropathy

Marcellin, Patrick, Wursthorn, Karsten, Wedemeyer, Heiner, Chuang, Wan-Long, Lau, George, Avila, Claudio, Peng, Cheng-Yuan, Gane, Edward, Lim, Seng Gee, Fainboim, Hugo, Foster, Graham R., Safadi, Rifa

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 678 KB

english, 2015

89

Efficacy and safety of 12 weeks versus 18 weeks of treatment with grazoprevir (MK-5172) and elbasvir (MK-8742) with or without ribavirin for hepatitis C virus genotype 1 infection in previously untreated patients with cirrhosis and patients with previous null response with or without cirrhosis (C-WORTHY): a randomised, open-label phase 2 trial

Lawitz, Eric, Gane, Edward, Pearlman, Brian, Tam, Edward, Ghesquiere, Wayne, Guyader, Dominique, Alric, Laurent, Bronowicki, Jean-Pierre, Lester, Laura, Sievert, William, Ghalib, Reem, Balart, Luis, S

Journal:

Year:

2015

Language:

english

File:

PDF, 621 KB

english, 2015

90

Sofosbuvir and Ribavirin for Treatment of Compensated Recurrent Hepatitis C Virus Infection After Liver Transplantation

Charlton, Michael, Gane, Edward, Manns, Michael P., Brown, Robert S., Curry, Michael P., Kwo, Paul Y., Fontana, Robert J., Gilroy, Richard, Teperman, Lewis, Muir, Andrew J., McHutchison, John G., Symo

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 11.08 MB

english, 2015

91

Response-guided peginterferon therapy in hepatitis B e antigen-positive chronic hepatitis B using serum hepatitis B surface antigen levels

Sonneveld, Milan J., Hansen, Bettina E., Piratvisuth, Teerha, Jia, Ji-Dong, Zeuzem, Stefan, Gane, Edward, Liaw, Yun-Fan, Xie, Qing, Heathcote, E. Jenny, Chan, Henry L.-Y., Janssen, Harry L.A.

Journal:

Year:

2013

Language:

english

File:

PDF, 4.24 MB

english, 2013

92

Twenty-eight day safety, antiviral activity, and pharmacokinetics of tenofovir alafenamide for treatment of chronic hepatitis B infection

Agarwal, Kosh, Fung, Scott K., Nguyen, Tuan T., Cheng, Wendy, Sicard, Eric, Ryder, Stephen D., Flaherty, John F., Lawson, Eileen, Zhao, Sally, Subramanian, G. Mani, McHutchison, John G., Gane, Edward

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

93

Efficacy and Safety of Faldaprevir, Deleobuvir, and Ribavirin in Treatment-Naive Patients with Chronic Hepatitis C Virus Infection and Advanced Liver Fibrosis or Cirrhosis

Zeuzem, Stefan, Soriano, Vicente, Asselah, Tarik, Gane, Edward J., Bronowicki, Jean-Pierre, Angus, Peter, Lohse, Ansgar W., Stickel, Felix, Müllhaupt, Beat, Roberts, Stuart, Schuchmann, Marcus, Manns,

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 697 KB

english, 2015

94

Long-Term Outcome of Hepatitis C Infection after Liver Transplantation

Gane, Edward J., Portmann, Bernard C., Naoumov, Nikolai V., Smith, Heather M., Underhill, James A., Donaldson, Peter T., Maertens, Geert, Williams, Roger

Journal:

Boston Medical and Surgical Journal

Year:

1996

Language:

english

File:

PDF, 120 KB

english, 1996

95

Reimbursement policies in the Asia-Pacific for chronic hepatitis B

Lim, Seng Gee, Amarapurkar, Deepak N., Chan, Henry Lik-Yuen, Crawford, Darrell H., Gane, Edward J., Han, Kwang-Hyub, Ahn, Sang Hoon, Jafri, Wasim, Jia, Jidong, Kao, Jia-Horng, Lesmana, Laurentius A.,

Journal:

Hepatology International

Year:

2015

Language:

english

File:

PDF, 178 KB

english, 2015

96

The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection

Gane, Edward J., Lim, Young-Suk, Gordon, Stuart C., Visvanathan, Kumar, Sicard, Eric, Fedorak, Richard N., Roberts, Stuart, Massetto, Benedetta, Ye, Zhishen, Pflanz, Stefan, Garrison, Kimberly L., Gag

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 780 KB

english, 2015

97

Long-term clinical outcomes in cirrhotic chronic hepatitis B patients treated with tenofovir disoproxil fumarate for up to 5 years

Buti, Maria, Fung, Scott, Gane, Edward, Afdhal, Nezam H., Flisiak, Robert, Gurel, Selim, Flaherty, John F., Martins, Eduardo B., Yee, Leland J., Dinh, Phillip, Bornstein, Jeffrey D., Mani Subramanian,

Journal:

Hepatology International

Year:

2015

Language:

english

File:

PDF, 302 KB

english, 2015

98

Sofosbuvir plus pegylated interferon and ribavirin in patients with genotype 1 hepatitis C virus in whom previous therapy with direct-acting antivirals has failed

Pol, Stanislas, Sulkowski, Mark S., Hassanein, Tarek, Gane, Edward J., Liu, Lin, Mo, Hongmei, Doehle, Brian, Kanwar, Bittoo, Brainard, Diana, Subramanian, G. Mani, Symonds, William T., McHutchison, Jo

Journal:

Year:

2015

Language:

english

File:

PDF, 3.75 MB

english, 2015

99

365 Ledipasvir/Sofosbuvir With Ribavirin Is Safe and Efficacious in Decompensated and Post Liver Transplantation Patients With HCV Infection: Preliminary Results of the Prospective SOLAR 2 Trial

Gane, Edward, Manns, Michael P., Forns, Xavier, Samuel, Didier, Charlton, Michael R., Denning, Jill, Arterburn, Sarah, Brandt-Sarif, Theo S., Pang, Phil, McHutchison, John G., Mutimer, David

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 304 KB

english, 2015

100

901f Efficacy and Safety of Grazoprevir/Elbasvir ± Ribavirin (RBV) for 12 or 16 Weeks in Patients With HCV G1, G4, or G6 Infection Who Previously Failed Peginterferon/RBV: C-EDGE Treatment-Experienced Trial

Kwo, Paul Y, Gane, Edward, Peng, Cheng-Yuan, Pearlman, Brian, Vierling, John M, Serfaty, Lawrence, Buti, Maria, Shafran, Stephen D, Stryszak, Paul, Lin, Li, Gress, Jacqueline O, Robertson, Michael, Wa

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015