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51

CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter

Andreia M. Ionescu, Hicham Drissi, Edward M. Schwarz, Mitsuyasu Kato, J. Edward Puzas, Dennis J. McCance, Randy N. Rosier, Michael J. Zuscik, Regis J. O'Keefe

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 288 KB

english, 2004

52

PTHrP expression in chick sternal chondrocytes is regulated by TGF-β through Smad-mediated signaling

Dhruv B. Pateder, Cristin M. Ferguson, Andreia M. Ionescu, Edward M. Schwarz, Randy N. Rosier, J. Edward Puzas, Regis J. O'Keefe

Journal:

Journal of Cellular Physiology

Year:

2001

Language:

english

File:

PDF, 273 KB

english, 2001

53

Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

Nathan Smith, Yufeng Dong, Jane B. Lian, Jitesh Pratap, Paul D. Kingsley, Andre J. van Wijnen, Janet L. Stein, Edward M. Schwarz, Regis J. O'Keefe, Gary S. Stein, M. Hicham Drissi

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 600 KB

english, 2005

54

Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor

Yu-Feng Dong, Do Y. Soung, Edward M. Schwarz, Regis J. O'Keefe, Hicham Drissi

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 428 KB

english, 2006

55

Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification

Lee A. Kaback, Do Y. Soung, Amish Naik, Nathan Smith, Edward M. Schwarz, Regis J. O'Keefe, Hicham Drissi

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 430 KB

english, 2008

56

Effects of transforming growth factor-β1 and fibroblast growth factor on DNA synthesis in growth plate chondrocytes are enhanced by insulin-like growth factor-I

Regis J. O'Keefe, Ian D. Crabb, J. Edward Puzas, Dr. Randy N. Rosier

Journal:

Journal of Orthopaedic Research

Year:

1994

Language:

english

File:

PDF, 1.07 MB

english, 1994

57

Differential regulation of type-II and type-X collagen synthesis by parathyroid hormone-related protein in chick growth-plate chondrocytes

Regis J. O'Keefe, Luke S. Loveys, David G. Hicks, Paul R. Reynolds, Ian D. Crabb, J. Edward Puzas, Randy N. Rosier

Journal:

Journal of Orthopaedic Research

Year:

1997

Language:

english

File:

PDF, 1.30 MB

english, 1997

58

Bone morphogenetic protein-7 in growth-plate chondrocytes: Regulation by retinoic acid is dependent on the stage of chondrocyte maturation

Christopher D. Grimsrud, Randy N. Rosier, J Edward Puzas, Paul R. Reynolds, Susan D. Reynolds, David G. Hicks, Regis J. O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

1998

Language:

english

File:

PDF, 2.63 MB

english, 1998

59

Interleukin-10 inhibits cytokine synthesis in monocytes stimulated by titanium particles: Evidence of an anti-inflammatory regulatory pathway

Paul F. Pollice, James Hsu, David G. Hicks, Susan Bukata, Randy N. Rosier, Paul R. Reynolds, J. Edward Puzas, Regis J. O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

1998

Language:

english

File:

PDF, 877 KB

english, 1998

60

Tumor necrosis factor-α/nuclear transcription factor-κB signaling in periprosthetic osteolysis

Edward M. Schwarz, Allen P. Lu, J. Jeffrey Goater, Eric B. Benz, George Kollias, Randy N. Rosier, J. Edward Puzas, Regis J. O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2000

Language:

english

File:

PDF, 1.01 MB

english, 2000

61

Quantitative small-animal surrogate to evaluate drug efficacy in preventing wear debris-induced osteolysis

Edward M. Schwarz, Eric B. Benz, Allen P. Lu, J. Jeffrey Goater, Anthony V. Mollano, Randy N. Rosier, J. Edward Puzas, Regis J. O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2000

Language:

english

File:

PDF, 856 KB

english, 2000

62

Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity

Dan Li, Kirill Gromov, Kjeld Søballe, J. Edward Puzas, Regis J. O'Keefe, Hani Awad, Hicham Drissi, Edward M. Schwarz

Journal:

Journal of Orthopaedic Research

Year:

2008

Language:

english

File:

PDF, 456 KB

english, 2008

63

Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT

Ryosuke Tsutsumi, Colleen Hock, C. Dustin Bechtold, Steven T. Proulx, Susan V. Bukata, Hiromu Ito, Hani A. Awad, Takashi Nakamura, Regis J. O'Keefe, Edward M. Schwarz

Journal:

Journal of Orthopaedic Research

Year:

2008

Language:

english

File:

PDF, 436 KB

english, 2008

64

Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression

Alayna E. Loiselle, Gwynne A. Bragdon, Justin A. Jacobson, Sys Hasslund, Zenia E. Cortes, Edward M. Schwarz, David J. Mitten, Hani A. Awad, Regis J. O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

65

Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis

Daniel P. Crane, Kirill Gromov, Dan Li, Kjeld Søballe, Christian Wahnes, Hubert Büchner, Matthew J. Hilton, Regis J. O'Keefe, Clinton K. Murray, Edward M. Schwarz

Journal:

Journal of Orthopaedic Research

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

66

The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy

Erik R. Sampson, Vinit Amin, Edward M. Schwarz, Regis J. O'Keefe, Randy N. Rosier

Journal:

Journal of Orthopaedic Research

Year:

2011

Language:

english

File:

PDF, 6.52 MB

english, 2011

67

Establishment of an index with increased sensitivity for assessing murine arthritis

Erik R. Sampson, Christopher A. Beck, John Ketz, Krista L. Canary, Matthew J. Hilton, Hani Awad, Edward M. Schwarz, Di Chen, Regis J. O'Keefe, Randy N. Rosier, Michael J. Zuscik

Journal:

Journal of Orthopaedic Research

Year:

2011

Language:

english

File:

PDF, 1.91 MB

english, 2011

68

Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression

Chao Xie, Edward M. Schwarz, Erik R. Sampson, Robinder S. Dhillon, Dan Li, Regis J. O'Keefe, Wakenda Tyler

Journal:

Journal of Orthopaedic Research

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

69

Immunohistochemical study of receptor activator of nuclear factor kappa-B ligand (RANK-L) in human osteolytic bone tumors

Christopher R. Good, Regis J. O'Keefe, J. Edward Puzas, Edward M. Schwarz, Randy N. Rosier

Journal:

Journal of Surgical Oncology

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

70

Proteolytic domains of the epidermal growth factor receptor of human placenta

Edward J. O'Keefe, Teresa K. Battin, Vann Bennett

Journal:

Journal of Cellular Biochemistry

Year:

1981

Language:

english

File:

PDF, 1.00 MB

english, 1981

71

Fission origin of the Moon: Cause and timing

John A. O'Keefe, Edward S. Sullivan

Journal:

Year:

1978

Language:

english

File:

PDF, 894 KB

english, 1978

72

Identification of phases in zinc alloy powders using electron backscatter diffraction

Martin G. Perez, Edward A. Kenik, Matthew J. O’Keefe, F. Scott Miller, Benedict Johnson

Journal:

Materials Science and Engineering: A

Year:

2006

Language:

english

File:

PDF, 1.17 MB

english, 2006

73

A novel murine segmental femoral graft model

Prarop Tiyapatanaputi, Paul T. Rubery, Jonathan Carmouche, Edward M. Schwarz, Regis J. O'Keefe, Xinping Zhang

Journal:

Journal of Orthopaedic Research

Year:

2004

Language:

english

File:

PDF, 955 KB

english, 2004

74

Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: A role for free radicals, NFkB, and TNFα

Alexander Soloviev, Edward M. Schwarz, Michael Darowish, Regis J. O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2005

Language:

english

File:

PDF, 835 KB

english, 2005

75

p38 MAP kinase inhibitors. Part 5: Discovery of an orally bio-available and highly efficacious compound based on the 7-amino-naphthyridone scaffold

Swaminathan R. Natarajan, Luping Liu, Mark Levorse, James E. Thompson, Edward A. O’Neill, Stephen J. O’Keefe, Kalpit A. Vora, Raymond Cvetovich, John Y. Chung, Ester Carballo-Jane, Denise M. Visco

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

76

Synthesis and biological activity of quinolinone and dihydroquinolinone p38 MAP kinase inhibitors

Meng-Hsin Chen, Patricia Fitzgerald, Suresh B. Singh, Edward A. O’Neill, Cheryl D. Schwartz, Chris M. Thompson, Stephen J. O’Keefe, Dennis M. Zaller, James B. Doherty

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 146 KB

english, 2008

77

Synthesis and biological activity of 2H-quinolizin-2-one based p38α MAP kinase inhibitors

Robert M. Tynebor, Meng-Hsin Chen, Swaminathan R. Natarajan, Edward A. O’Neill, James E. Thompson, Catherine E. Fitzgerald, Stephen J. O’Keefe, James B. Doherty

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

78

Synthesis and biological activity of pyridopyridazin-6-one p38 MAP kinase inhibitors. Part 1

Robert M. Tynebor, Meng-Hsin Chen, Swaminathan R. Natarajan, Edward A. O’Neill, James E. Thompson, Catherine E. Fitzgerald, Stephen J. O’Keefe, James B. Doherty

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 705 KB

english, 2011

79

Transforming growth factor-β1 induced alteration of skeletal morphogenesis in vivo

Cristin M Ferguson, Edward M Schwarz, J.Edward Puzas, Michael J Zuscik, Hicham Drissi, Regis J O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2004

Language:

english

File:

PDF, 1.30 MB

english, 2004

80

BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog

Christopher D Grimsrud, Paul R Romano, Mary D'Souza, J Edward Puzas, Edward M Schwarz, Paul R Reynolds, Randy N Roiser, Regis J O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2001

Language:

english

File:

PDF, 1.28 MB

english, 2001

81

Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis

J Jeffrey Goater, Regis J O'Keefe, Randy N Rosier, J Edward Puzas, Edward M Schwarz

Journal:

Journal of Orthopaedic Research

Year:

2002

Language:

english

File:

PDF, 589 KB

english, 2002

82

COX-1 and COX-2 expression in osteoid osteomas

David V Mungo, Xinping Zhang, Regis J O'Keefe, Randy N Rosier, J Edward Puzas, Edward M Schwarz

Journal:

Journal of Orthopaedic Research

Year:

2002

Language:

english

File:

PDF, 422 KB

english, 2002

83

Lead alters parathyroid hormone-related peptide and transforming growth factor-β1 effects and AP-1 and NF-κB signaling in chondrocytes

Michael J Zuscik, Dhruv B Pateder, J Edward Puzas, Edward M Schwarz, Randy N Rosier, Regis J O'Keefe

Journal:

Journal of Orthopaedic Research

Year:

2002

Language:

english

File:

PDF, 861 KB

english, 2002

84

Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A

Michael J. Zuscik, Regis J. O'Keefe, Thomas E. Gunter, J. Edward Puzas, Edward M. Schwarz, Randy N. Rosier

Journal:

Journal of Orthopaedic Research

Year:

2002

Language:

english

File:

PDF, 1.21 MB

english, 2002

85

Smad6 is induced by BMP-2 and modulates chondrocyte differentiation

Xeufeng Li, Andreia M Ionescu, Edward M Schwarz, Xinping Zhang, Hicham Drissi, J.Edward Puzas, Randy N Rosier, Michael J Zuscik, Regis J O’Keefe

Journal:

Journal of Orthopaedic Research

Year:

2003

Language:

english

File:

PDF, 594 KB

english, 2003

86

Effects of receptor activator of NFκB (RANK) signaling blockade on fracture healing

Lisa M Flick, Jason M Weaver, Michael Ulrich-Vinther, Faruk Abuzzahab, Xinping Zhang, William C Dougall, Dirk Anderson, Regis J O’Keefe, Edward M Schwarz

Journal:

Journal of Orthopaedic Research

Year:

2003

Language:

english

File:

PDF, 1.05 MB

english, 2003

87

Use of volumetric computerized tomography as a primary outcome measure to evaluate drug efficacy in the prevention of peri-prosthetic osteolysis: a 1-year clinical pilot of etanercept vs. placebo

Edward M Schwarz, Debbie Campbell, Saara Totterman, Allen Boyd, Regis J O’Keefe, R.John Looney

Journal:

Journal of Orthopaedic Research

Year:

2003

Language:

english

File:

PDF, 722 KB

english, 2003

88

Pyridazine based inhibitors of p38 MAPK

Charles J McIntyre, Gerald S Ponticello, Nigel J Liverton, Stephen J O’Keefe, Edward A O’Neill, Margaret Pang, Cheryl D Schwartz, David A Claremon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 143 KB

english, 2002

89

p38 Inhibitors: piperidine- and 4-aminopiperidine-substituted naphthyridinones, quinolinones, and dihydroquinazolinones

Julianne A Hunt, Florida Kallashi, Rowena D Ruzek, Peter J Sinclair, Ida Ita, Sherrie X McCormick, James V Pivnichny, C.E.C.A Hop, Sanjeev Kumar, Zhen Wang, Stephen J O'Keefe, Edward A O'Neill, Gene P

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 182 KB

english, 2003

90

Tyrosine Phosphorylation of Human Keratinocyte β-Catenin and Plakoglobin Reversibly Regulates their Binding to E-Cadherin and α-Catenin

Hu, Peiqi, O'Keefe, Edward J., Rubenstein, David S.

Journal:

The Journal of Investigative Dermatology

Year:

2001

Language:

english

File:

PDF, 278 KB

english, 2001

91

Keratinocyte Adherens Junctions Initiate Nuclear Signaling byTranslocation of Plakoglobin from the Membrane to the Nucleus

Hu, Peiqi, Berkowitz, Paula, O'Keefe, Edward J, Rubenstein, David S

Journal:

The Journal of Investigative Dermatology

Year:

2003

Language:

english

File:

PDF, 582 KB

english, 2003

92

Nitrate removal in the hyporheic zone of a salmon river in Alaska

Gilles Pinay, Thomas C. O'Keefe, Richard T. Edwards, Robert J. Naiman

Journal:

River Research and Applications

Year:

2009

Language:

english

File:

PDF, 192 KB

english, 2009

93

Differential effects of parathyroid hormone on chick growth plate and articular chondrocytes

Ian D. Crabb, Regis J. O'Keefe, J. Edward Puzas, Randy N. Rosier

Journal:

Calcified Tissue International

Year:

1992

Language:

english

File:

PDF, 989 KB

english, 1992

94

On the independence of primal algebras

Edward S. O'Keefe

Journal:

Mathematische Zeitschrift

Year:

1960

Language:

english

File:

PDF, 664 KB

english, 1960

95

Interdisciplinary agreement in the diagnosis of headache types

Edward B. Blanchard, Dennis O'Keefe, Debra Neff, Susan Jurish, Frank Andrasik

Journal:

Journal of Psychopathology and Behavioral Assessment

Year:

1981

Language:

english

File:

PDF, 203 KB

english, 1981

96

Cholera toxin and membrane gangliosides: Binding and adenylate cyclase activation in normal and transformed cells

Edward O'Keefe, Pedro Cuatrecasas

Journal:

Journal of Membrane Biology

Year:

1978

Language:

english

File:

PDF, 1.09 MB

english, 1978

97

Cyclosporin A and FK-506: Immunosuppression, inhibition of transcription and the role of calcineurin

Stephen J. O'Keefe, Edward A. O'Neill

Journal:

Perspectives in Drug Discovery and Design

Year:

1994

Language:

english

File:

PDF, 1.68 MB

english, 1994

98

Effect of transforming growth factor-β on DNA synthesis by growth plate chondrocytes: Modulation by factors present in serum

Regis J. O'Keefe, J. Edward Puzas, John S. Brand, Randy N. Rosier

Journal:

Calcified Tissue International

Year:

1988

Language:

english

File:

PDF, 761 KB

english, 1988

99

The effect of keratinocyte growth factor on tumour growth and small intestinal mucositis after chemotherapy in the rat with breast cancer

Rachel J. Gibson, Dorothy M. Keefe, Julie M. Clarke, Geoff O. Regester, Fiona M. Thompson, Gary J. Goland, Ben G. Edwards, Adrian G. Cummins

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 364 KB

english, 2002

100

Potential Denitrification Activity in the Landscape of a Western Alaska Drainage Basin

G. Pinay, T. O’Keefe, R. Edwards, Robert J. Naiman

Journal:

Year:

2003

Language:

english

File:

PDF, 482 KB

english, 2003

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