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1

Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation

Maura Greiser, Hans-Ruprecht Neuberger, Erik Harks, Ali El-Armouche, Peter Boknik, Sunniva de Haan, Fons Verheyen, Sander Verheule, Wilhelm Schmitz, Ursula Ravens, Stanley Nattel, Maurits A. Allessie,

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2009

Language:

english

File:

PDF, 1.52 MB

english, 2009

2

Terminal Differentiation, Advanced Organotypic Maturation, and Modeling of Hypertrophic Growth in Engineered Heart Tissue

Tiburcy, M., Didie, M., Boy, O., Christalla, P., Doker, S., Naito, H., Karikkineth, B. C., El-Armouche, A., Grimm, M., Nose, M.

Journal:

Circulation Research

Year:

2011

Language:

english

File:

PDF, 5.71 MB

english, 2011

3

A novel player in cellular hypertrophy: Giβγ/PI3K-dependent activation of the RacGEF TIAM-1 is required for α1-adrenoceptor induced hypertrophy in neonatal rat cardiomyocytes

Christiane Vettel, Karola Wittig, Andreas Vogt, Christina M. Wuertz, Ali El-Armouche, Susanne Lutz, Thomas Wieland

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

4

Post-column infusion of internal standard quantification for liquid chromatography-electrospray ionization-tandem mass spectrometry analysis – Pharmaceuticals in urine as example approach

Rossmann, Julia, Renner, Lars David, Oertel, Reinhard, El-Armouche, Ali

Journal:

Journal of Chromatography A

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

5

AAV-9 mediated phosphatase-1 inhibitor-1 overexpression improves cardiac contractility in unchallenged mice but is deleterious in pressure-overload

Schwab, D M, Tilemann, L, Bauer, R, Heckmann, M, Jungmann, A, Wagner, M, Burgis, J, Vettel, C, Katus, H A, El-Armouche, A, Müller, O J

Journal:

Year:

2018

Language:

english

File:

PDF, 948 KB

english, 2018

6

Curriculum Kardiologie; Curriculum cardiology;

Werdan, K., Baldus, St., Bauersachs, J., Baumgartner, H., Bongarth, C. M., Buerke, M., DÃ¶rr, R., Duncker, D., Eckardt, L., El-Armouche, A., ElsÃ¤sser, A., Fach, A., Flachskampf, F. A., Gabelmann, M.,

Journal:

Year:

2020

File:

PDF, 632 KB

2020

7

Phosphatase-1-inhibitor-1: amplifier or attenuator of catecholaminergic stress?

Katrin Wittköpper, Thomas Eschenhagen, Ali El-Armouche

Journal:

Basic Research in Cardiology

Year:

2010

Language:

english

File:

PDF, 140 KB

english, 2010

8

Endoreplication and polyploidy in primary culture of rat hepatic stellate cells

Jozsef Dudas, Bernhard Saile, Hamudi El-Armouche, Isabella Aprigliano, Giuliano Ramadori

Journal:

Cell and Tissue Research

Year:

2003

Language:

english

File:

PDF, 869 KB

english, 2003

9

β-Adrenergic stimulation and myocardial function in the failing heart

Ali El-Armouche, Thomas Eschenhagen

Journal:

Heart Failure Reviews

Year:

2009

Language:

english

File:

PDF, 566 KB

english, 2009

10

Febuxostat, ein neues Pharmakon zur Behandlung der Gicht

P. Christalla, K. Wittköpper, A. El-Armouche

Journal:

Year:

2011

Language:

german

File:

PDF, 313 KB

german, 2011

11

IGF-I induces DNA synthesis and apoptosis in rat liver hepatic stellate cells (HSC) but DNA synthesis and proliferation in rat liver myofibroblasts (rMF)

Saile, Bernhard, DiRocco, Paola, Dudas, Joszef, El-Armouche, Hammudeh, Sebb, Holger, Eisenbach, Christoph, Neubauer, Katrin, Ramadori, Giuliano

Journal:

Laboratory Investigation

Year:

2004

Language:

english

File:

PDF, 450 KB

english, 2004

12

The MLCK-mediated α1-adrenergic inotropic effect in atrial myocardium is negatively modulated by PKCɛ signaling

Michael Grimm, Nina Mahnecke, Friederike Soja, Ali El-Armouche, Pascal Haas, Hendrik Treede, Hermann Reichenspurner, Thomas Eschenhagen

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 311 KB

english, 2006

13

Vareniclin – Erhöhtes kardiovaskuläres Risiko bei der Raucherentwöhnung?

Dewenter, M., El-Armouche, A.

Journal:

Year:

2012

Language:

german

File:

PDF, 265 KB

german, 2012

14

Antiapoptotic effect of interferon-α on hepatic stellate cells (HSC): A novel pathway of IFN-α signal transduction via Janus kinase 2 (JAK2) and caspase-8

Bernhard Saile, Christoph Eisenbach, Hammoudeh El-Armouche, Katrin Neubauer, Giuliano Ramadori

Journal:

European Journal of Cell Biology

Year:

2003

Language:

english

File:

PDF, 275 KB

english, 2003

15

Interferon-γ acts proapoptotic on hepatic stellate cells (HSC) and abrogates the antiapoptotic effect of interferon-α by an HSP70-dependant pathway

Bernhard Saile, Christoph Eisenbach, Jozsef Dudas, Hammoudeh El-Armouche, Giuliano Ramadori

Journal:

European Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 363 KB

english, 2004

16

Ouabain treatment is associated with upregulation of phosphatase inhibitor-1 and Na+/Ca2+-exchanger and β-adrenergic sensitization in rat hearts

Ali El-Armouche, Elmar Jaeckel, Kenneth R Boheler, Peter Boknik, Boris Hertle, Joachim Neumann, Thomas Eschenhagen

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 260 KB

english, 2004

17

Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes

Ali El-Armouche, Anna Bednorz, Torsten Pamminger, Diana Ditz, Michael Didié, Dobromir Dobrev, Thomas Eschenhagen

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 511 KB

english, 2006

18

The new HNO donor, 1-nitrosocyclohexyl acetate, increases contractile force in normal and β-adrenergically desensitized ventricular myocytes

Ali El-Armouche, Azadeh Wahab, Katrin Wittköpper, Thomas Schulze, Felix Böttcher, Lutz Pohlmann, S. Bruce King, Jenna F. DuMond, Christian Gerloff, Rainer H. Böger, Thomas Eschenhagen, Lucie Carrier,

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 526 KB

english, 2010

19

Phospholamban and troponin I phosphorylation in remodeled left atria from patients with sinus rhythm and chronic atrial fibrillation

Ali El-Armouche, Michael Knaut, Thomas Eschenhagen, Ursula Ravens, Dobromir Dobrev

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

20

Reduced contractile response to α1-adrenergic stimulation in atria from mice with chronic cardiac calmodulin kinase II inhibition

Michael Grimm, Ali El-Armouche, Rong Zhang, Mark E. Anderson, Thomas Eschenhagen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 738 KB

english, 2007

21

Adenovirus-delivered short hairpin RNA targeting PKCα improves contractile function in reconstituted heart tissue

Ali El-Armouche, Jasmin Singh, Hiroshi Naito, Katrin Wittköpper, Michael Didié, Alexander Laatsch, Wolfram-Hubertus Zimmermann, Thomas Eschenhagen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 647 KB

english, 2007

22

Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure

Ali El-Armouche, Lutz Pohlmann, Saskia Schlossarek, Jutta Starbatty, Yung-Hsin Yeh, Stanley Nattel, Dobromir Dobrev, Thomas Eschenhagen, Lucie Carrier

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 592 KB

english, 2007

23

Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization

Alexander Peter Schwoerer, Ivan Melnychenko, Diane Goltz, Nils Hedinger, Irene Broichhausen, Ali El-Armouche, Thomas Eschenhagen, Tilmann Volk, Heimo Ehmke

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 874 KB

english, 2008

24

Inducible and cardiac specific inhibitor-1 overexpression enhances contractile performance in the murine heart

K. Wittköpper, B. Unsöld, T. Eschenhagen, A. El-Armouche

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 77 KB

english, 2008

25

Mechanical unloading of the rat heart involves marked changes in the protein kinase–phosphatase balance

Alexander P. Schwoerer, Christiane Neuber, Ariane Schmechel, Ivan Melnychenko, Giulia Mearini, Peter Boknik, Uwe Kirchhefer, Wilhelm Schmitz, Heimo Ehmke, Thomas Eschenhagen, Ali El-Armouche

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 667 KB

english, 2008

26

The Four and a Half LIM-Domain 2 Controls Early Cardiac Cell Commitment and Expansion Via Regulating β-Catenin-Dependent Transcription

Renger, Anke, Zafiriou, Maria-Patapia, Noack, Claudia, Pavlova, Elena, Becker, Alexander, Sharkova, Krasimira, Bergmann, Martin W., El-Armouche, Ali, Zimmermann, Wolfram-Hubertus, Zelarayán, Laura C.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.25 MB

english, 2013

27

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart

Heijman, Jordi, Dewenter, Matthias, El-Armouche, Ali, Dobrev, Dobromir

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

28

Cellular Ca2+ Handling in Cardiac Atrophy and Hypertrophy

Schwoerer, A.P., Biermann, D., Boknik, P., El-Armouche, A., Eschenhagen, T., Volk, T., Reichenspurner, H., Ehmke, H.

Journal:

The Journal of Heart and Lung Transplantation

Year:

2014

Language:

english

File:

PDF, 68 KB

english, 2014

29

While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice

Neef, Stefan, Sag, Can M., Daut, Maria, Bäumer, Henrik, Grefe, Clemens, El-Armouche, Ali, DeSantiago, Jaime, Pereira, Laetitia, Bers, Donald M., Backs, Johannes, Maier, Lars S.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 657 KB

english, 2013

30

Paradoxical Effects on Force Generation after Efficient 1-Adrenoceptor Knockdown in Reconstituted Heart Tissue

Neuber, C., Muller, O. J., Hansen, F. C., Eder, A., Witten, A., Ruhle, F., Stoll, M., Katus, H. A., Eschenhagen, T., El-Armouche, A.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

31

Erythropoietin Responsive Cardiomyogenic Cells Contribute to Heart Repair Post Myocardial Infarction

Zafiriou, Maria Patapia, Noack, Claudia, Unsöld, Bernhard, Didie, Michael, Pavlova, Elena, Fischer, Henrike J., Reichardt, Holger M., Bergmann, Martin W., El-Armouche, Ali, Zimmermann, Wolfram-Hubertu

Journal:

Year:

2014

Language:

english

File:

PDF, 1.87 MB

english, 2014

32

Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes

Haj Slimane, Z., Bedioune, I., Lechene, P., Varin, A., Lefebvre, F., Mateo, P., Domergue-Dupont, V., Dewenter, M., Richter, W., Conti, M., El-Armouche, A., Zhang, J., Fischmeister, R., Vandecasteele,

Journal:

Cardiovascular Research

Year:

2014

Language:

english

File:

PDF, 897 KB

english, 2014

33

PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways

Vettel, C., Lammle, S., Ewens, S., Cervirgen, C., Emons, J., Ongherth, A., Dewenter, M., Lindner, D., Westermann, D., Nikolaev, V. O., Lutz, S., Zimmermann, W. H., El-Armouche, A.

Journal:

AJP Heart and Circulatory Physiology

Year:

2014

Language:

english

File:

PDF, 829 KB

english, 2014

34

Dopamine and Lipophilic Derivates Protect Cardiomyocytes against Cold Preservation Injury

Vettel, C., Hottenrott, M. C., Spindler, R., Benck, U., Schnuelle, P., Tsagogiorgas, C., Kramer, B. K., Hoeger, S., El-Armouche, A., Wieland, T., Yard, B. A.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2013

Language:

english

File:

PDF, 306 KB

english, 2013

35

Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects

Schmechel, A., Grimm, M., El-Armouche, A., Hoppner, G., Schwoerer, A. P., Ehmke, H., Eschenhagen, T.

Journal:

Cardiovascular Research

Year:

2009

Language:

english

File:

PDF, 279 KB

english, 2009

36

Age-dependent changes in contractile function and passive elastic properties of myocardium from mice lacking muscle LIM protein (MLP)

Unsöld, Bernhard, Schotola, Hanna, Jacobshagen, Claudius, Seidler, Tim, Sossalla, Samuel, Emons, Julius, Klede, Stefanie, Knöll, Ralph, Guan, Kaomei, El-Armouche, Ali, Linke, Wolfgang A., Kögler, Hara

Journal:

European Journal of Heart Failure

Year:

2012

Language:

english

File:

PDF, 371 KB

english, 2012

37

Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure

Journal:

Cardiovascular Research

Year:

2003

Language:

english

File:

PDF, 321 KB

english, 2003

38

Unfavourable consequences of chronic cardiac HIF-1 stabilization

Holscher, M., Schafer, K., Krull, S., Farhat, K., Hesse, A., Silter, M., Lin, Y., Pichler, B. J., Thistlethwaite, P., El-Armouche, A., Maier, L. S., Katschinski, D. M., Zieseniss, A.

Journal:

Cardiovascular Research

Year:

2012

Language:

english

File:

PDF, 598 KB

english, 2012

39

Development of phosphatase inhibitor-1 peptides acting as indirect activators of phosphatase 1

Sotoud, Hannieh, Borgmeyer, Uwe, Schulze, Christian, El-Armouche, Ali, Eschenhagen, Thomas

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

40

Microdomain Switch of cGMP-Regulated Phosphodiesterases Leads to ANP-Induced Augmentation of -Adrenoceptor-Stimulated Contractility in Early Cardiac Hypertrophy

Perera, R. K., Sprenger, J. U., Steinbrecher, J. H., Hubscher, D., Lehnart, S. E., Abesser, M., Schuh, K., El-Armouche, A., Nikolaev, V. O.

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 4.94 MB

english, 2015

41

Evidence for protein phosphatase inhibitor-1 playing an amplifier role in β-adrenergic signaling in cardiac myocytes

El-Armouche, A.

Journal:

The FASEB Journal

Year:

2003

Language:

english

File:

PDF, 1.10 MB

english, 2003

42

Phosphorylation of Protein Phosphatase Inhibitor-1 by Protein Kinase C

Sahin, Bogachan, Shu, Hongjun, Fernandez, Joseph, El-Armouche, Ali, Molkentin, Jeffery D., Nairn, Angus C., Bibb, James A.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

43

Phospholemman-dependent regulation of the cardiac Na/K-ATPase activity is modulated by inhibitor-1 sensitive type-1 phosphatase

El-Armouche, A., Wittkopper, K., Fuller, W., Howie, J., Shattock, M. J., Pavlovic, D.

Journal:

The FASEB Journal

Year:

2011

Language:

english

File:

PDF, 604 KB

english, 2011

44

Cardiac Myosin-Binding Protein C Is Required for Complete Relaxation in Intact Myocytes

Pohlmann, L., Kroger, I., Vignier, N., Schlossarek, S., Kramer, E., Coirault, C., Sultan, K. R., El-Armouche, A., Winegrad, S., Eschenhagen, T., Carrier, L.

Journal:

Circulation Research

Year:

2007

Language:

english

File:

PDF, 1004 KB

english, 2007

45

Follistatin-Like 1 in Chronic Systolic Heart Failure: A Marker of Left Ventricular Remodeling

El-Armouche, A., Ouchi, N., Tanaka, K., Doros, G., Wittkopper, K., Schulze, T., Eschenhagen, T., Walsh, K., Sam, F.

Journal:

Circulation Heart Failure

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

46

Development of a Colorimetric and a Fluorescence Phosphatase-Inhibitor Assay Suitable for Drug Discovery Approaches

Sotoud, H., Gribbon, P., Ellinger, B., Reinshagen, J., Boknik, P., Kattner, L., El-Armouche, A., Eschenhagen, T.

Journal:

Journal of Biomolecular Screening

Year:

2013

Language:

english

File:

PDF, 952 KB

english, 2013

47

Inhibition of Elevated Ca2+/Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium

Sossalla, S., Fluschnik, N., Schotola, H., Ort, K. R., Neef, S., Schulte, T., Wittkopper, K., Renner, A., Schmitto, J. D., Gummert, J., El-Armouche, A., Hasenfuss, G., Maier, L. S.

Journal:

Circulation Research

Year:

2010

Language:

english

File:

PDF, 727 KB

english, 2010

48

Prevention of Myofilament Dysfunction by -Blocker Therapy in Postinfarct Remodeling

Duncker, D. J., Boontje, N. M., Merkus, D., Versteilen, A., Krysiak, J., Mearini, G., El-Armouche, A., de Beer, V. J., Lamers, J. M.J., Carrier, L., Walker, L. A., Linke, W. A., Stienen, G. J.M., van

Journal:

Circulation Heart Failure

Year:

2009

Language:

english

File:

PDF, 573 KB

english, 2009

49

Ca2+-Related Signaling and Protein Phosphorylation Abnormalities Play Central Roles in a New Experimental Model of Electrical Storm

Tsuji, Y., Hojo, M., Voigt, N., El-Armouche, A., Inden, Y., Murohara, T., Dobrev, D., Nattel, S., Kodama, I., Kamiya, K.

Journal:

Year:

2011

Language:

english

File:

PDF, 4.29 MB

english, 2011

50

Reduced Phospholamban Phosphorylation Is Associated With Impaired Relaxation in Left Ventricular Myocytes From Neuronal NO Synthase-Deficient Mice

Zhang, Y. H., Zhang, M. H., Sears, C. E., Emanuel, K., Redwood, C., El-Armouche, A., Kranias, E. G., Casadei, B.

Journal:

Circulation Research

Year:

2008

Language:

english

File:

PDF, 843 KB

english, 2008