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51

ChemInform Abstract: Synthesis of 3′-Amino-3′-deoxyguanosine and 3′-Amino-3′-deoxyxyloguanosine Monophosphate Hepdirect Prodrugs from Guanosine.

Brett C. Bookser, Nicholas B. Raffaele, K. Raja Reddy, Kevin Fan, Wenjian Huang, Mark D. Erion

Journal:

Year:

2010

File:

PDF, 20 KB

2010

52

Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist

Edward E. Cable, Patricia D. Finn, Jeffrey W. Stebbins, Jinzhao Hou, Bruce R. Ito, Paul D. van Poelje, David L. Linemeyer, Mark D. Erion

Journal:

Year:

2009

Language:

english

File:

PDF, 704 KB

english, 2009

53

Toxicity and dosimetry of 177Lu-DOTA-Y3-octreotate in a rat model

Jason S. Lewis, Mu Wang, Richard Laforest, Fan Wang, Jack L. Erion, Joseph E. Bugaj, Ananth Srinivasan, Carolyn J. Anderson

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

54

Ab initio quantum mechanics-based free energy perturbation method for calculating relative solvation free energies

M. Rami Reddy, U. C. Singh, Mark D. Erion

Journal:

Journal of Computational Chemistry

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

55

Probing the conformational space available to inhibitors in the thermolysin active site using Monte Carlo/energy minimization techniques

Wayne C. Guida, Regine S. Bohacek, Mark D. Erion

Journal:

Journal of Computational Chemistry

Year:

1992

Language:

english

File:

PDF, 1.12 MB

english, 1992

56

Assessment of methods used for predicting lipophilicity: Application to nucleosides and nucleoside bases

Vellarkad N. Viswanadhan, M. Rami Reddy, Russell J. Bacquet, Mark D. Erion

Journal:

Journal of Computational Chemistry

Year:

1993

Language:

english

File:

PDF, 728 KB

english, 1993

57

A radioimmunoassay for measuring α-amidating enzyme activity

Arco Y. Jeng, Mary Wong, Susan J. Lovato, Mark D. Erion, James P. Gilligan

Journal:

Analytical Biochemistry

Year:

1990

Language:

english

File:

PDF, 558 KB

english, 1990

58

Bis[(para-methoxy)benzyl] phosphonate prodrugs with improved stability and enhanced cell penetration

Qun Dang, Yan Liu, Robert M. Rydzewski, Brian S. Brown, Edward Robinson, Paul D. van Poelje, Timothy J. Colby, Mark D. Erion

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 154 KB

english, 2007

59

The correntropy MACE filter

Kyu-Hwa Jeong, Weifeng Liu, Seungju Han, Erion Hasanbelliu, Jose C. Principe

Journal:

Pattern Recognition

Year:

2009

Language:

english

File:

PDF, 1.36 MB

english, 2009

60

Distributed computation of the knn graph for large high-dimensional point sets

Erion Plaku, Lydia E. Kavraki

Journal:

Journal of Parallel and Distributed Computing

Year:

2007

Language:

english

File:

PDF, 446 KB

english, 2007

61

GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function

Tamas L. Horvath, Derek M. Erion, John D. Elsworth, Robert H. Roth, Gerald I. Shulman, Zane B. Andrews

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 2.26 MB

english, 2011

62

A parallel 3D particle-in-cell code with dynamic load balancing

Felix Wolfheimer, Erion Gjonaj, Thomas Weiland

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2006

Language:

english

File:

PDF, 226 KB

english, 2006

63

Stereoselective synthesis of nucleoside monophosphate HepDirect™ prodrugs

K. Raja Reddy, Serge H. Boyer, Mark D. Erion

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 105 KB

english, 2005

64

An unexpected cyclization discovered during the synthesis of 8-substituted purines from a 4,5-diaminopyrimidine

Qun Dang, Robert M. Rydzewski, Daniel K. Cashion, Mark D. Erion

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 105 KB

english, 2008

65

A new intermediate in the synthesis of a tritiated cytokinin with high specific activity

J.Eugene Fox, Jack L. Erion, James D. McChesney

Journal:

Year:

1979

Language:

english

File:

PDF, 205 KB

english, 1979

66

An efficient method for the conversion of alkylmercuric halides into olefins

Mark D. Erion, John E. McMurry

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 189 KB

english, 1985

67

Stereoselective synthesis of 4-C-methyl-2,3,5-tri-O-benzyl-d-ribofuranose and 4-C-methyl-2,3,5-tri-O-benzyl-l-lyxofuranose

Serge H Boyer, Bheemarao G Ugarkar, Mark D Erion

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 231 KB

english, 2003

68

Synthesis of phosphonate 3-phthalidyl esters as prodrugs for potential intracellular delivery of phosphonates

Qun Dang, Brian S. Brown, Paul D. van Poelje, Timothy J. Colby, Mark D. Erion

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 352 KB

english, 1999

69

Fast and reliable analysis of molecular motion using proximity relations and dimensionality reduction

Erion Plaku, Hernán Stamati, Cecilia Clementi, Lydia E. Kavraki

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 1.20 MB

english, 2007

70

The plastome mutator ofOenotheracontinues to function as originally described

Melvin D. Epp, Jack L. Erion, Barbara B. Sears, Wilfried Stubbe

Journal:

Molecular Genetics and Genomics

Year:

1987

Language:

english

File:

PDF, 347 KB

english, 1987

71

Synthesis of the large subunit of ribulose-1,5-bisphosphate carboxylase in anin vitropartially definedE. colisystem

Jack L. Erion, Joseph Tarnowski, Susan Peacock, Paul Caldwell, Betty Redfield, Nathan Brot, Herbert Weissbach

Journal:

Plant Molecular Biology

Year:

1983

Language:

english

File:

PDF, 1.15 MB

english, 1983

72

Characterization of the mRNA transcripts of the maize, ribulose-1,5-bisphosphate carboxylase, large subunit gene

Journal:

Plant Molecular Biology

Year:

1985

Language:

english

File:

PDF, 1.33 MB

english, 1985

73

Hypoglycaemic effect of AICAriboside in mice

M. F. Vincent, M. D. Erion, H. E. Gruber, G. Van den Berghe

Journal:

Year:

1996

Language:

english

File:

PDF, 812 KB

english, 1996

74

Knockdown of the gene encodingDrosophila tribbleshomologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance

D. Weismann, D. M. Erion, I. Ignatova-Todorava, Y. Nagai, R. Stark, J. J. Hsiao, C. Flannery, A. L. Birkenfeld, T. May, M. Kahn, D. Zhang, X. X. Yu, S. F. Murray, S. Bhanot, B. P. Monia, G. W. Cline,

Journal:

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

75

Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat

M. Futamura, J. Yao, X. Li, R. Bergeron, J.-L. Tran, E. Zycband, J. Woods, Y. Zhu, Q. Shao, H. Maruki-Uchida, H. Goto-Shimazaki, R. B. Langdon, M. D. Erion, J. Eiki, Y.-P. Zhou

Journal:

Year:

2012

Language:

english

File:

PDF, 366 KB

english, 2012

76

Stabilised111In-labelled DTPA- and DOTA-conjugated neurotensin analogues for imaging and therapy of exocrine pancreatic cancer

M. de Visser, P. J. J. M. Janssen, A. Srinivasan, J. C. Reubi, B. Waser, J. L. Erion, M. A. Schmidt, E. P. Krenning, M. de Jong

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

77

Novel111In-labelled bombesin analogues for molecular imaging of prostate tumours

M. de Visser, H. F. Bernard, J. L. Erion, M. A. Schmidt, A. Srinivasan, B. Waser, J. C. Reubi, E. P. Krenning, M. de Jong

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 275 KB

english, 2007

78

Comparison of three radiolabelled peptide analogues for CCK-2 receptor scintigraphy in medullary thyroid carcinoma

Alida C. Fröberg, Marion de Jong, Berthold A. Nock, Wout A. P. Breeman, Jack L. Erion, Theodosia Maina, Marion Verdijsseldonck, Wouter W. de Herder, Aad van der Lugt, Peter P. M. Kooij, Eric P. Krenni

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

79

Cholecystokinin receptor imaging using an octapeptide DTPA-CCK analogue in patients with medullary thyroid carcinoma

Dik J. Kwekkeboom, Willem H. Bakker, Peter P.M. Kooij, Jack Erion, Ananth Srinivasan, Marion de Jong, Jean-Claude Reubi, Eric P. Krenning

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

80

Unsulfated DTPA- and DOTA-CCK analogs as specific high-affinity ligands for CCK-B receptor-expressing human and rat tissues in vitro and in vivo

J. C. Reubi, B. Waser, J. C. Schaer, U. Laederach, J. Erion, A. Srinivasan, M. A. Schmidt, J. E. Bugaj

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1998

Language:

english

File:

PDF, 675 KB

english, 1998

81

[177Lu-DOTA0,Tyr3]octreotate: comparison with [111In-DTPA0]octreotide in patients

Dik J. Kwekkeboom, Willem H. Bakker, Peter P. Kooij, Mark W. Konijnenberg, Ananth Srinivasan, Jack L. Erion, Michelle A. Schmidt, Joe L. Bugaj, Marion de Jong, Eric P. Krenning

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2001

Language:

english

File:

PDF, 96 KB

english, 2001

82

Delivery of high levels of anti-proliferative nucleoside triphosphates to CYP3A-expressing cells as a potential treatment for hepatocellular carcinoma

Deidre A. MacKenna, Annika Montag, Serge H. Boyer, David L. Linemeyer, Mark D. Erion

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 584 KB

english, 2009

83

Hybrid systems: from verification to falsification by

Erion Plaku, Lydia E. Kavraki, Moshe Y. Vardi

Journal:

Formal Methods in System Design

Year:

2009

Language:

english

File:

PDF, 980 KB

english, 2009

84

Relative solvation free energies calculated using an ab initio QM/MM-based free energy perturbation method: dependence of results on simulation length

M. Rami Reddy, Mark D. Erion

Journal:

Journal of Computer-Aided Molecular Design

Year:

2009

Language:

english

File:

PDF, 276 KB

english, 2009

85

Thyroid hormone β receptor activation has additive cholesterol lowering activity in combination with atorvastatin in rabbits, dogs and monkeys

BR Ito, B-H Zhang, EE Cable, X Song, JM Fujitaki, DA MacKenna, CE Wilker, B Chi, PD Van Poelje, DL Linemeyer, MD Erion

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 343 KB

english, 2009

86

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

Andrews, Zane B., Liu, Zhong-Wu, Walllingford, Nicholas, Erion, Derek M., Borok, Erzsebet, Friedman, Jeffery M., Tschöp, Matthias H., Shanabrough, Marya, Cline, Gary, Shulman, Gerald I.

Journal:

Year:

2008

Language:

english

File:

PDF, 606 KB

english, 2008

87

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

Andrews, Zane B., Liu, Zhong-Wu, Walllingford, Nicholas, Erion, Derek M., Borok, Erzsebet, Friedman, Jeffery M., Tschöp, Matthias H., Shanabrough, Marya, Cline, Gary, Shulman, Gerald I.

Journal:

Year:

2009

File:

PDF, 35 KB

2009

88

Hidden alternative structures of proline isomerase essential for catalysis

Fraser, James S., Clarkson, Michael W., Degnan, Sheena C., Erion, Renske, Kern, Dorothee, Alber, Tom

Journal:

Year:

2009

Language:

english

File:

PDF, 781 KB

english, 2009

89

STAT3 inhibition of gluconeogenesis is downregulated by SirT1

Nie, Yongzhan, Erion, Derek M., Yuan, Zhenglong, Dietrich, Marcelo, Shulman, Gerald I., Horvath, Tamas L., Gao, Qian

Journal:

Nature Cell Biology

Year:

2009

Language:

english

File:

PDF, 2.79 MB

english, 2009

90

Diacylglycerol-mediated insulin resistance

Erion, Derek M, Shulman, Gerald I

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 871 KB

english, 2010

91

SirT1 Regulates Adipose Tissue Inflammation

Gillum, M. P., Kotas, M. E., Erion, D. M., Kursawe, R., Chatterjee, P., Nead, K. T., Muise, E. S., Hsiao, J. J., Frederick, D. W., Yonemitsu, S.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

92

Use of a QM/MM-Based FEP Method to Evaluate the Anomalous Hydration Behavior of Simple Alkyl Amines and Amides: Application to the Design of FBPase Inhibitors for the Treatment of Type-2 Diabetes

Reddy, M. Rami, Singh, U. Chandra, Erion, Mark D.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 682 KB

english, 2011

93

Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(Arylmethyl) derivatives of 9-deazaguanine

Montgomery, John A., Niwas, Shri, Rose, Jerry D., Secrist, John A., Babu, Y. Sudhakar, Bugg, Charles E., Erion, Mark D., Guida, Wayne C., Ealick, Steven E.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 3.31 MB

english, 1993

94

Adenosine Kinase Inhibitors. 3. Synthesis, SAR, and Antiinflammatory Activity of a Series of l-Lyxofuranosyl Nucleosides

Ugarkar, Bheemarao G., Castellino, Angelo J., DaRe, Jay S., Ramirez-Weinhouse, Michele, Kopcho, Joseph J., Rosengren, Sanna, Erion, Mark D.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

95

Adenosine Kinase Inhibitors. 6. Synthesis, Water Solubility, and Antinociceptive Activity of 5-Phenyl-7-(5-deoxy-β-d-ribofuranosyl)pyrrolo[2,3-d]pyrimidines Substituted at C4 with Glycinamides and Related Compounds

Bookser, Brett C., Ugarkar, Bheemarao G., Matelich, Michael C., Lemus, Robert H., Allan, Matthew, Tsuchiya, Megumi, Nakane, Masami, Nagahisa, Atsushi, Wiesner, James B., Erion, Mark D.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 218 KB

english, 2005

96

ChemInform Abstract: 5-Aminopyrazoles as Dienophiles in the Inverse Electron Demand Diels- Alder Reactions of 2,4,6-Tris(ethoxycarbonyl)-1,3,5-triazine: Syntheses of Pyrazolopyrimidines.

Q. DANG, B. S. BROWN, M. D. ERION

Journal:

Year:

1996

File:

PDF, 29 KB

1996

97

Insulinotropic Action of Formycin A

W.J. Malaisse, A. Sener, H.E. Gruber, M.D. Erion

Journal:

Biochemical Medicine and Metabolic Biology

Year:

1994

File:

PDF, 444 KB

1994

98

The addition of DTPA to [177Lu-DOTA0,Tyr3]octreotate prior to administration reduces rat skeleton uptake of radioactivity

Breeman, Wouter A., van der Wansem, Katy, Bernard, Bert F., van Gameren, Arthur, Erion, Jack L., Visser, Theo J., Krenning, Eric P., de Jong, M.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

99

Optimising conditions for radiolabelling of DOTA-peptides with90Y,111In and177Lu at high specific activities

Breeman, Wouter A. P., Jong, Marion, Visser, Theo J., Erion, Jack L., Krenning, Eric P.

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

100

The structure of human 5′-deoxy-5′-methylthioadenosine phosphorylase at 1.7 Å resolution provides insights into substrate binding and catalysis

Todd C Appleby, Mark D Erion, Steven E Ealick

Journal:

Year:

1999

Language:

english

File:

PDF, 777 KB

english, 1999