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1

Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis

Ortiz, Francisco, Acuña-Castroviejo, Darío, Doerrier, Carolina, Dayoub, José C., López, Luis C., Venegas, Carmen, García, José A., López, Ana, Volt, Huayqui, Luna-Sánchez, Marta, Escames, Germaine

Journal:

Journal of Pineal Research

Year:

2015

Language:

english

File:

PDF, 2.42 MB

english, 2015

2

Long-term melatonin administration protects brain mitochondria from aging

Miguel Carretero, Germaine Escames, Luis C. López, Carmen Venegas, José C. Dayoub, L. García, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

3

Melatonin mitigates mitochondrial malfunction

Josefa León, Darío Acuña-Castroviejo, Germane Escames, Dun-Xian Tan, Russel J. Reiter

Journal:

Journal of Pineal Research

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

4

Extrapineal melatonin: sources, regulation, and potential functions

Acuña-Castroviejo, Darío, Escames, Germaine, Venegas, Carmen, Díaz-Casado, María E., Lima-Cabello, Elena, López, Luis C., Rosales-Corral, Sergio, Tan, Dun-Xian, Reiter, Russel J.

Journal:

Cellular and Molecular Life Sciences

Year:

2014

Language:

english

File:

PDF, 837 KB

english, 2014

5

Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse

Yoelvis García-Mesa, Lydia Giménez-Llort, Luis C. López, Carmen Venegas, Rosa Cristòfol, Germain Escames, Darío Acuña-Castroviejo, Coral Sanfeliu

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 3.50 MB

english, 2012

6

Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo

M. Martín, M. Macías, G. Escames, R.J. Reiter, M.T. Agapito, G.G. Ortiz, D. Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2000

Language:

english

File:

PDF, 311 KB

english, 2000

7

Chronic melatonin treatment prevents age-dependent cardiac mitochondrial dysfunction in senescence-accelerated mice

Rodríguez, María I., Carretero, Miguel, Escames, Germaine, López, Luis C., Maldonado, María D., Tan, Dun-Xian, Reiter, Russel J., Acuña-Castroviejo, Darío

Journal:

Free Radical Research

Year:

2007

Language:

english

File:

PDF, 552 KB

english, 2007

8

Protective Effects of Melatonin on the Skin: Future Perspectives

Rusanova, Iryna, Martínez-Ruiz, Laura, Florido, Javier, Rodríguez-Santana, César, Guerra-Librero, Ana, Acuña-Castroviejo, Darío, Escames, Germaine

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.33 MB

english, 2019

9

Argan Oil-contained Antioxidants for Human Mitochondria

López, Luis C., Cabrera-Vique, Carmen, Venegas, Carmen, García-Corzo, Laura, Luna-Sánchez, Marta, Acuña-Castroviejo, Darío, Escames, Germaine

Journal:

Natural Product Communications

Year:

2013

Language:

english

File:

PDF, 259 KB

english, 2013

10

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

Carmen Venegas, José A. García, Germaine Escames, Francisco Ortiz, Ana López, Carolina Doerrier, Laura García-Corzo, Luis C. López, Russel J. Reiter, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2012

Language:

english

File:

PDF, 344 KB

english, 2012

11

Melatonin treatment normalizes plasma pro-inflammatory cytokines and nitrosative/oxidative stress in patients suffering from Duchenne muscular dystrophy

Mariam Chahbouni, Germaine Escames, Carmen Venegas, Belén Sevilla, José Antonio García, Luis C. López, Antonio Muñoz-Hoyos, Antonio Molina-Carballo, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2010

Language:

english

File:

PDF, 191 KB

english, 2010

12

Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin

Volt, Huayqui, García, José A., Doerrier, Carolina, Díaz-Casado, María E., Guerra-Librero, Ana, López, Luis C., Escames, Germaine, Tresguerres, Jesús A., Acuña-Castroviejo, Darío

Journal:

Journal of Pineal Research

Year:

2016

Language:

english

File:

PDF, 948 KB

english, 2016

13

Antioxidant defence and inflammatory response in professional road cyclists during a 4-day competition

Serrano, Eric, Venegas, Carmen, Escames, Germaine, Sánchez-Muñoz, Cristóbal, Zabala, Mikel, Puertas, Araceli, de Haro, Tomas, Gutierrez, Angel, Castillo, Manuel, Acuna-Castroviejo, Dario

Journal:

Journal of Sports Sciences

Year:

2010

Language:

english

File:

PDF, 269 KB

english, 2010

14

Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome

Rahim, Ibtissem, Sayed, Ramy K., FernÃ¡ndez-Ortiz, Marisol, Aranda-MartÃnez, Paula, Guerra-Librero, Ana, FernÃ¡ndez-MartÃnez, JosÃ©, Rusanova, Iryna, Escames, Germaine, Djerdjouri, Bahia, AcuÃ±a-Cas

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2020

File:

PDF, 2.15 MB

2020

15

The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS

Ortiz, Francisco, García, José A., Acuña-Castroviejo, Darío, Doerrier, Carolina, López, Ana, Venegas, Carmen, Volt, Huayqui, Luna-Sánchez, Marta, López, Luis C., Escames, Germaine

Journal:

Journal of Pineal Research

Year:

2014

Language:

english

File:

PDF, 722 KB

english, 2014

16

Melatonin-mitochondria Interplay in Health and Disease

Acuna Castroviejo, Dario, C. Lopez, Luis, Escames, Germaine, Lopez, Ana, A. Garcia, Jose, J. Reiter, Russel

Journal:

Current Topics in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 525 KB

english, 2011

17

Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network

Doerrier, Carolina, García, José A., Volt, Huayqui, Díaz-Casado, María E., Luna-Sánchez, Marta, Fernández-Gil, Beatriz, Escames, Germaine, López, Luis C., Acuña-Castroviejo, Darío

Journal:

Year:

2016

Language:

english

File:

PDF, 993 KB

english, 2016

18

Envejecimiento del sistema circadiano

Alejandro Lucas-Sánchez, Antonio Martinez-Nicolas, Germaine Escames, Jorge de Costa

Journal:

Revista Española de Geriatría y Gerontología

Year:

2012

File:

PDF, 443 KB

2012

19

Disruption of the NF- B/NLRP3 connection by melatonin requires retinoid-related orphan receptor- and blocks the septic response in mice

Garcia, J. A., Volt, H., Venegas, C., Doerrier, C., Escames, G., Lopez, L. C., Acuna-Castroviejo, D.

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 2.80 MB

english, 2015

20

The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance trained athletes

Leonardo-Mendonça, Roberto C, Ocaña-Wilhelmi, Javier, de Haro, Tomás, de Teresa-Galván, Carlos, Guerra-Hernández, Eduardo, Rusanova, Iryna, Fernández-Ortiz, Marisol, Sayed, Ramy KA, Escames, Germaine,

Journal:

Applied Physiology Nutrition and Metabolism

Year:

2017

Language:

english

File:

PDF, 664 KB

english, 2017

21

Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis

Rahim, Ibtissem, Djerdjouri, Bahia, Sayed, Ramy K., Fernández-Ortiz, Marisol, Fernández-Gil, Beatriz, Hidalgo-Gutiérrez, Agustín, López, Luis C., Escames, Germaine, Reiter, Russel J., Acuña-Castroviej

Journal:

Journal of Pineal Research

Year:

2017

Language:

english

File:

PDF, 714 KB

english, 2017

22

Melatonin, clock genes and mitochondria in sepsis

Acuña-Castroviejo, Darío, Rahim, Ibtissem, Acuña-Fernández, Carlos, Fernández-Ortiz, Marisol, Solera-Marín, Jorge, Sayed, Ramy K. A., Díaz-Casado, María E., Rusanova, Iryna, López, Luis C., Escames, G

Journal:

Cellular and Molecular Life Sciences

Year:

2017

Language:

english

File:

PDF, 1.94 MB

english, 2017

23

Melatonin-Induced Oncostasis, Mechanisms and Clinical Relevance

Cardinali, Daniel, Escames, Germaine

Journal:

Journal of Integrative Oncology

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

24

The Protective Effect of Melatonin Against Age-Associated Sarcopenia-Dependent Tubular Aggregates Formation, Lactate Depletion and Mitochondrial Changes

Sayed, Ramy K A, Fernández-Ortiz, Marisol, Diaz-Casado, María E, Rusanova, Iryna, Rahim, Ibtissem, Escames, Germaine, López, Luis C, Mokhtar, Doaa M, Acuña-Castroviejo, Darío

Journal:

The Journals of Gerontology Series A Biological Sciences and Medical Sciences

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

25

PO-089: Melatonin enhances the toxicity of radio- and chemotherapy in head and neck cancer cells

Escames, G., Fernández-Gil, B.I., Guerra-Librero, A., Shen, Y., García-López, S., Florido, J., Sayed, R., Acuña-Castroviejo, D., Esposito, J.

Journal:

Radiotherapy and Oncology

Year:

2017

Language:

english

File:

PDF, 364 KB

english, 2017

26

Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice

María I. Rodríguez, Germaine Escames, Luis C. López, Ana López, José A. García, Francisco Ortiz, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2007

Language:

english

File:

PDF, 978 KB

english, 2007

27

Improved mitochondrial function and increased life span after chronic melatonin treatment in senescent prone mice

María I. Rodríguez, Germaine Escames, Luis C. López, Ana López, José A. García, Francisco Ortiz, Vanesa Sánchez, Marta Romeu, Darío Acuña-Castroviejo

Journal:

Experimental Gerontology

Year:

2008

Language:

english

File:

PDF, 382 KB

english, 2008

28

Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice

Sayed, Ramy K.A., de Leonardis, Erika Chacin, Guerrero-Martínez, José A., Rahim, Ibtissem, Mokhtar, Doaa M., Saleh, Abdelmohaimen M., Abdalla, Kamal E.H., Pozo, María J., Escames, Germaine, López, Lui

Journal:

Experimental Gerontology

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

29

Specific binding of melatonin to purified cell nuclei from mammary gland of swiss mice: day–night variations and effect of continuous light

Ana Coto-Montes, Cristina Tomás-Zapico, Germaine Escames, Josefa León, María Josefa Rodríguez-Colunga, Delio Tolivia, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2003

Language:

english

File:

PDF, 157 KB

english, 2003

30

Melatonin protects lung mitochondria from aging

Darío Acuña-Castroviejo, Miguel Carretero, Carolina Doerrier, Luis C. López, Laura García-Corzo, Jesús A. Tresguerres, Germaine Escames

Journal:

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

31

Exercise and melatonin in humans: reciprocal benefits

Germaine Escames, Guler Ozturk, Beatriz Baño-Otálora, María J. Pozo, Juan A. Madrid, Russel J. Reiter, Eric Serrano, Melquiades Concepción, Dario Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2012

Language:

english

File:

PDF, 216 KB

english, 2012

32

Protective effects of melatonin against oxidative damage induced by Egyptian cobra (Naja haje) crude venom in rats

Abdel Moneim, Ahmed E., Ortiz, Francisco, Leonardo-Mendonça, Roberto C., Vergano-Villodres, Roberto, Guerrero-Martínez, Jose Antonio, López, Luis C., Acuña-Castroviejo, Darío, Escames, Germaine

Journal:

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

33

PO-0960: Clinical application of a new pharmaceutical formulation of melatonin against radiotherapy-induced mucositis

Escames, G., Ortiz, F., Vergano-Villodres, R., Guerrero-Martínez, J., Acuña-Castroviejo, D., López, L.C., Martinez Unica, A., Martínez Carrillo, M., Tovar-Martin, I., Expósito Hernández, J.

Journal:

Radiotherapy and Oncology

Year:

2014

Language:

english

File:

PDF, 235 KB

english, 2014

34

Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis

Rodríguez-Hidalgo, María, Luna-Sánchez, Marta, Hidalgo-Gutiérrez, Agustín, Barriocanal-Casado, Eliana, Mascaraque, Cristina, Acuña-Castroviejo, Darío, Rivera, Margarita, Escames, Germaine, López, Luis

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.12 MB

english, 2018

35

Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in rats

CRESPO, ELENA, MACÍAS, MANUEL, POZO, DAVID, ESCAMES, GERMAINE, MARTÍN, MIGUEL, VIVES, FRANCISCO, GUERRERO, JUAN M., ACUÑA-CASTROVIEJO, DARÍO

Journal:

The FASEB Journal

Year:

1999

Language:

english

File:

PDF, 346 KB

english, 1999

36

Electrophysiological response of neurons of the mediodorsal nucleus of the thalamus to the stimulation of the nucleus accumbens in the rat

J.M. Salmerón, G. Escames, J.M. Pérez-Jaranay, F. Vives

Journal:

Neuroscience Research Communications

Year:

1996

Language:

english

File:

PDF, 370 KB

english, 1996

37

β-globin gene cluster haplotypes in sickle cell patients from Panamá

Iryna Rusanova, Gladys Cossio, Bélgica Moreno, F. Javier Perea, Rosaura G. De Borace, Mauricio Perea, Germaine Escames, Darío Acuña-Castroviejo

Journal:

American Journal of Human Biology

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

38

Melatonin, mitochondria, and cellular bioenergetics

Darío Acuña-Castroviejo, Miguel Martín, Manuel Macías, Germaine Escames, Josefa León, Huda Khaldy, Russel J. Reiter

Journal:

Journal of Pineal Research

Year:

2001

Language:

english

File:

PDF, 197 KB

english, 2001

39

Changes in brain amino acids and nitric oxide after melatonin administration in rats with pentylenetetrazole-induced seizures

Leila Bikjdaouene, Germaine Escames, Josefa León, José M. R. Ferrer, Hoda Khaldy, Francisco Vives, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2003

Language:

english

File:

PDF, 376 KB

english, 2003

40

Characterization of melatonin high-affinity binding sites in purified cell nuclei of the hamster (Mesocricetus auratus) harderian gland

Ana Coto-Montes, Cristina Tomás-Zapico, Germaine Escames, Josefa León, Delio Tolivia, Mª JosefaRodríguez-Colunga, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2003

Language:

english

File:

PDF, 233 KB

english, 2003

41

Effects of some synthetic kynurenines on brain amino acids and nitric oxide after pentylenetetrazole administration to rats

Leila Bikjdaouene, Germaine Escames, Encarnación Camacho, Josefa León, José M. R. Ferrer, Antonio Espinosa, Miguel A. Gallo, Juan De Dios Luna, Darío Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2004

Language:

english

File:

PDF, 598 KB

english, 2004

42

Prophylactic Actions of Melatonin in Oxidative Neurotoxicity

RUSSEL J. REITER, JUAN M. GUERRERO, GERMAINE ESCAMES, MIGUEL A. PAPPOLLA, DARIO ACUÑA-CASTROVIEJO

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 604 KB

english, 1997

43

Effect of propranolol plus exercise on melatonin and growth hormone levels in children with growth delay

A. Muñoz-Hoyos, E. Hubber, G. Escames, A. Molina-Carballo, M. Macías, A. Valenzuela-Ruiz, J.M. Fernández-García, D. Acuña-Castroviejo

Journal:

Journal of Pineal Research

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

44

Modification of Nitric Oxide Synthase Activity and Neuronal Response in Rat Striatum by Melatonin and Kynurenine Derivatives

Josefa León, Francisco Vives, Elena Crespo, Encarnación Camacho, Antonio Espinosa, MigueL. A. Gallo, Germaine Escames, Darío Acuña-Castroviejo

Journal:

Journal of Neuroendocrinology

Year:

1998

Language:

english

File:

PDF, 107 KB

english, 1998

45

Calreticulin–melatonin : An unexpected relationship

Manuel Macías, Germaine Escames, Josefa Leon, Ana Coto, Younes Sbihi, Antonio Osuna, Darío Acuña-Castroviejo

Journal:

Year:

2003

Language:

english

File:

PDF, 255 KB

english, 2003

46

Melatonin in the oral cavity: physiological and pathological implications

Reiter, R. J., Rosales-Corral, S. A., Liu, X. Y., Acuna-Castroviejo, D., Escames, G., Tan, D.-X.

Journal:

Journal of Periodontal Research

Year:

2015

Language:

english

File:

PDF, 154 KB

english, 2015

47

Calcium-Dependent Effects of Melatonin Inhibition of Glutamatergic Response in Rat Striatum

G. Escames, M. Macías, J. León, J. García, H. Khaldy, M. Martín, F. Vives, D. Acuña-Castroviejo

Journal:

Journal of Neuroendocrinology

Year:

2001

Language:

english

File:

PDF, 327 KB

english, 2001

48

Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation

Joaquı́n J Garcı́a, Russel J Reiter, Juan M Guerrero, Germaine Escames, Byung P Yu, Chang S Oh, Antonio Muñoz-Hoyos

Journal:

Year:

1997

Language:

english

File:

PDF, 401 KB

english, 1997

49

CADD-28. MELATONIN: TARGETING THE CELL’S POWERHOUSE TO FIGHT GLIOBLASTOMA

Fernandez-Gil, Beatriz I, Schiappareli, Paula, Vazquez-Ramos, Carla, Sarabia-Estrada, Rachel, Escames, Germaine, Quiñones-Hinojosa, Alfredo

Journal:

Year:

2018

File:

PDF, 119 KB

2018

50

Melatonin and its brain metabolite N1-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice

Víctor Tapias, Germaine Escames, Luis C. López, Ana López, Encarnación Camacho, María D. Carrión, Antonio Entrena, Miguel A. Gallo, Antonio Espinosa, Darío Acuña-Castroviejo

Journal:

Journal of Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 181 KB

english, 2009

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