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1

Protease-catalyzed fragment condensation via substrate mimetic strategy: a useful combination of solid-phase peptide synthesis with enzymatic methods

V. Čeřovský, F. Bordusa

Journal:

Chemical Biology & Drug Design

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

2

Electrical conductivity and translational diffusion in the 1-butyl-3-methylimidazolium tetrafluoroborate ionic liquid

Sangoro, J., Iacob, C., Serghei, A., Naumov, S., Galvosas, P., Kärger, J., Wespe, C., Bordusa, F., Stoppa, A., Hunger, J., Buchner, R., Kremer, F.

Journal:

The Journal of Chemical Physics

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

3

Charge transport and mass transport in imidazolium-based ionic liquids

Sangoro, J. R., Serghei, A., Naumov, S., Galvosas, P., Kärger, J., Wespe, C., Bordusa, F., Kremer, F.

Journal:

Physical Review E

Year:

2008

Language:

english

File:

PDF, 602 KB

english, 2008

4

Protease Catalysis Mediated by a Substrate Mimetic: A Novel Enzymatic Approach to the Synthesis of Carboxylic Acid Amides

Robert Günther, Frank Bordusa

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

5

Semisynthesis of Ht31(493–515): Involvement of PKA-Anchoring Proteins in the Regulation of the cAMP-Dependent Chloride Current in Heart Cells

Václav Cerovský, Jens Kockskämper, Helfried G. Glitsch, Frank Bordusa

Journal:

Year:

2000

Language:

english

File:

PDF, 79 KB

english, 2000

6

Enzymes for Peptide Cyclization

Journal:

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

7

Synthese von Neo-Peptidoglycanen: eine überraschende Aktivität proteolytischer Enzyme

Nicole Wehofsky, Reik Löser, Andrij Buchynskyy, Peter Welzel, Frank Bordusa

Journal:

Angewandte Chemie

Year:

2002

File:

PDF, 146 KB

2002

8

Synthesis of Neo-Peptidoglycans: An Unexpected Activity of Proteases

Nicole Wehofsky, Reik Löser, Andrij Buchynskyy, Peter Welzel, Frank Bordusa

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

9

Proteasekatalysierter Peptidaufbau vom N- zum C-Terminus: eine vorteilhafte Strategie

Frank Bordusa, Dr. Dirk Ullmann, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 411 KB

1997

10

Substratmimetica-vermittelte Peptidsynthese: eine Strategie zur spezifitätsunabhängigen, irreversiblen Ligation

Frank Bordusa, Dr. Dirk Ullmann, Christian Elsner, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 384 KB

1997

11

Exprimierte enzymatische Ligation zur Semisynthese chemisch modifizierter Proteine

Zuzana Machova, Regula von Eggelkraut-Gottanka, Nicole Wehofsky, Frank Bordusa, Annette G. Beck-Sickinger

Journal:

Angewandte Chemie

Year:

2003

Language:

german

File:

PDF, 114 KB

german, 2003

12

all-D-Polypeptide: Zielmoleküle für die Semisynthese

Nicole Wehofsky, Sven Thust, Jens Burmeister, Sven Klussmann, Frank Bordusa

Journal:

Angewandte Chemie

Year:

2003

File:

PDF, 122 KB

2003

13

D-Aminosäure-spezifische Proteasen und native All-L-Proteine: eine zweckmäßige Kombination für die Semisynthese

Nicole Wehofsky, Andreas Pech, Sandra Liebscher, Stephanie Schmidt, Hidenobu Komeda, Yasuhisa Asano, Frank Bordusa

Journal:

Angewandte Chemie

Year:

2008

Language:

german

File:

PDF, 401 KB

german, 2008

14

Protease-Catalyzed Peptide Synthesis from N- to C-Terminus: An Advantageous Strategy

Frank Bordusa, Dr. Dirk Ullmann, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 442 KB

english, 1997

15

Substrate Mimetic Mediated Peptide Synthesis: An Irreversible Ligation Strategy That Is Independent of Substrate Specificity

Frank Bordusa, Dr. Dirk Ullmann, Christian Elsner, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 593 KB

english, 1997

16

Expressed Enzymatic Ligation for the Semisynthesis of Chemically Modified Proteins

Zuzana Machova, Regula von Eggelkraut-Gottanka, Nicole Wehofsky, Frank Bordusa, Annette G. Beck-Sickinger

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 114 KB

english, 2003

17

all-D-Polypeptides: Novel Targets for Semisynthesis

Nicole Wehofsky, Sven Thust, Jens Burmeister, Sven Klussmann, Frank Bordusa

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 113 KB

english, 2003

18

D-Amino Acid Specific Proteases and Native All-L-Proteins: A Convenient Combination for Semisynthesis

Nicole Wehofsky, Andreas Pech, Sandra Liebscher, Stephanie Schmidt, Hidenobu Komeda, Yasuhisa Asano, Frank Bordusa

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 389 KB

english, 2008

19

Book Review: Peptide Arrays on Membrane Supports—Synthesis and Applications. Editors Joachim Koch and Michael Mahler

Journal:

Year:

2003

Language:

english

File:

PDF, 48 KB

english, 2003

20

Ionic Liquids and Proteases: A Clean Alliance for Semisynthesis

Nicole Wehofsky, Christian Wespe, Vaclav Cerovsky, Andreas Pech, Eva Hoess, Rainer Rudolph, Frank Bordusa

Journal:

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

21

ChemInform Abstract: Protease-Catalyzed Peptide Synthesis from N- to C-Terminus: An Advantageous Strategy.

F. BORDUSA, D. ULLMANN, H.-D. JAKUBKE

Journal:

Year:

1997

File:

PDF, 25 KB

1997

22

ChemInform Abstract: Investigations on the Enzyme Specificity of Clostripain: A New Efficient Biocatalyst for the Synthesis of Peptide Isosteres.

Robert Guenther, Anja Stein, Frank Bordusa

Journal:

Year:

2000

File:

PDF, 25 KB

2000

23

ChemInform Abstract: Nonconventional Amide Bond Formation Catalysis: Programming Enzyme Specificity with Substrate Mimetics

Journal:

Year:

2001

File:

PDF, 26 KB

2001

24

ChemInform Abstract: Synthesizing Protease-Stable Isopeptides by Proteases: An Efficient Biocatalytic Approach on the Basis of a New Type of Substrate Mimetics.

Nicole Wehofsky, Mandy Alisch, Frank Bordusa

Journal:

Year:

2001

File:

PDF, 26 KB

2001

25

Proteases in Organic Synthesis

Journal:

Year:

2003

File:

PDF, 49 KB

2003

26

Assay of Diverse Protease Activities on the Basis of a Small Synthetic Substrate

Nora Müller, Frank Bordusa

Journal:

Analytical Biochemistry

Year:

2000

Language:

english

File:

PDF, 67 KB

english, 2000

27

Effect of freezing on the enzymatic coupling of specific amino acid-containing peptide fragments

Nicole Wehofsky, Marion Haensler, Sebastian W Kirbach, Johannes-Dieter Wissmann, Frank Bordusa

Journal:

Tetrahedron: Asymmetry

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

28

Synthesis of α-fluoroalkyl substituted peptides via enzymatic fragment condensation

Frank Bordusa, Christina Dahl, Hans-Dieter Jakubke, Klaus Burger, Beate Koksch

Journal:

Tetrahedron: Asymmetry

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

29

Trypsin-specific acyl-4-guanidinophenyl esters for α-chymotrypsin-catalysed reactions : Computational predictions, hydrolyses, and peptide bond formation

Robert Günther, Sven Thust, Hans-Jörg Hofmann, Frank Bordusa

Journal:

Year:

2000

Language:

english

File:

PDF, 452 KB

english, 2000

30

Peptide bond formation mediated by substrate mimetics : Structure-guided optimization of trypsin for synthesis

Raik Grünberg, Ines Domgall, Robert Günther, Kathrin Rall, Hans-Jörg Hofmann, Frank Bordusa

Journal:

Year:

2000

Language:

english

File:

PDF, 518 KB

english, 2000

31

Differences in the protein-kinase-A-dependent regulation of CFTR Cl–channels and Na+–K+pumps in guinea-pig ventricular myocytes

Jens Kockskämper, Kirsty Sendhoff, Simone Erlenkamp, Frank Bordusa, Vaclav Cerovsky, Helfried G. Glitsch

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 107 KB

english, 2001

32

A new simple route to the synthesis of protease substrates in ice

Dirk Ullmann, Frank Bordusa, Katrin Salchert, Hans-Dieter Jakubke

Journal:

Tetrahedron: Asymmetry

Year:

1996

Language:

english

File:

PDF, 408 KB

english, 1996

33

The specificity of Prolyl Endopeptidase from Flavobacterium meningoseptum: mapping the S′ subsites by positional scanning via acyl transfer

Frank Bordusa, Hans-Dieter Jakubke

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 202 KB

english, 1998

34

Structural Studies on Ionic Liquid/Water/Peptide Systems by HR-MAS NMR Spectroscopy

Dr. Carmen Mrestani-Klaus, Annekathrin Richardt, Dr. Christian Wespe, Dr. Annegret Stark, Eberhard Humpfer, Prof. Dr. Frank Bordusa

Journal:

Year:

2012

Language:

english

File:

PDF, 784 KB

english, 2012

35

Engineering of substrate mimetics as novel-type substrates for glutamic acid-specific endopeptidases: design, synthesis, and application

Nicole Wehofsky, Johannes-Dieter Wissmann, Mandy Alisch, Frank Bordusa

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2000

Language:

english

File:

PDF, 209 KB

english, 2000

36

Programming of enzyme specificity by substrate mimetics: investigations on the Glu-specific V8 protease reveals a novel general principle of biocatalysis

Nicole Wehofsky, Frank Bordusa

Journal:

Year:

1999

Language:

english

File:

PDF, 139 KB

english, 1999

37

New enzymatic segment coupling approach to bioactive peptides by specificity mimicry using substrate mimetics

Hans-Dieter Jakubke, Vaclav Cerovsky, Nicole Wehofsky, Katrin Rall, Frank Bordusa

Journal:

Regulatory Peptides

Year:

2000

Language:

english

File:

PDF, 131 KB

english, 2000

38

Proteases in Organic Synthesis †

Journal:

Chemical Reviews

Year:

2002

Language:

english

File:

PDF, 979 KB

english, 2002

39

Protease-Catalyzed Hydrolysis of Substrate Mimetics (Inverse Substrates): A New Approach Reveals a New Mechanism †,‡

Thormann, Michael, Thust, Sven, Hofmann, Hans-Jörg, Bordusa, Frank

Journal:

Year:

1999

Language:

english

File:

PDF, 129 KB

english, 1999

40

On the Nature of Interactions between Ionic Liquids and Small Amino-Acid-Based Biomolecules

Tietze, Alesia A., Bordusa, Frank, Giernoth, Ralf, Imhof, Diana, Lenzer, Thomas, Maaß, Astrid, Mrestani-Klaus, Carmen, Neundorf, Ines, Oum, Kawon, Reith, Dirk, Stark, Annegret

Journal:

Year:

2013

Language:

english

File:

PDF, 2.72 MB

english, 2013

41

Derivatization of Antibody Fab Fragments: A Designer Enzyme for Native Protein Modification

Liebscher, Sandra, Kornberger, Petra, Fink, Gerhard, Trost-Gross, Eva-Maria, Höss, Eva, Skerra, Arne, Bordusa, Frank

Journal:

Year:

2014

Language:

english

File:

PDF, 1.03 MB

english, 2014

42

Impact of ionic liquids on the structure of peptides proved by HR-MAS NMR spectroscopy

Richardt, Annekathrin, Mrestani-Klaus, Carmen, Bordusa, Frank

Journal:

Journal of Molecular Liquids

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

43

Investigations on the Enzyme Specificity of Clostripain: A New Efficient Biocatalyst for the Synthesis of Peptide Isosteres †

Günther, Robert, Stein, Anja, Bordusa, Frank

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 515 KB

english, 2000

44

Hofmeister Salts and Potential Therapeutic Compounds Accelerate in Vitro Fibril Formation of the N-Terminal Domain of PABPN1 Containing a Disease-Causing Alanine Extension

Lodderstedt, Grit, Sachs, Rolf, Faust, Jürgen, Bordusa, Frank, Kühn, Uwe, Golbik, Ralph, Kerth, Andreas, Wahle, Elmar, Balbach, Jochen, Schwarz, Elisabeth

Journal:

Year:

2008

File:

PDF, 14 KB

2008

45

The Protein-Free IANUS Peptide Array Uncovers Interaction Sites between Escherichia coli Parvulin 10 and Alkyl Hydroperoxide Reductase

Malešević, Miroslav, Poehlmann, Angela, Hernandez Alvarez, Birte, Diessner, André, Träger, Mario, Rahfeld, Jens-Ulrich, Jahreis, Günther, Liebscher, Sandra, Bordusa, Frank, Fischer, Gunter, Lück

Journal:

Year:

2010

Language:

english

File:

PDF, 4.01 MB

english, 2010

46

Substrate Mimetics-Specific Peptide Ligases: Studies on the Synthetic Utility of a Zymogen and Zymogen-Like Enzymes

Rall, Kathrin, Bordusa, Frank

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 85 KB

english, 2002

47

Substrate Mimetics and Freezing Strategy: A Useful Combination That Broadens the Scope of Proteases for Synthesis

Wehofsky, Nicole, Kirbach, Sebastian W., Haensler, Marion, Wissmann, Johannes-Dieter, Bordusa, Frank

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000

48

Enzymatic Coupling of Specific Peptides at Nonspecific Ligation Sites: Effect of Asp189Glu Mutation in Trypsin on Substrate Mimetic-Mediated Reactions †

Xu, Shaojun, Rall, Kathrin, Bordusa, Frank

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 62 KB

english, 2001

49

Hofmeister Salts and Potential Therapeutic Compounds Accelerate in Vitro Fibril Formation of the N-Terminal Domain of PABPN1 Containing a Disease-Causing Alanine Extension †

Lodderstedt, Grit, Sachs, Rolf, Faust, Jürgen, Bordusa, Frank, Kühn, Uwe, Golbik, Ralph, Kerth, Andreas, Wahle, Elmar, Balbach, Jochen, Schwarz, Elisabeth

Journal:

Year:

2008

Language:

english

File:

PDF, 317 KB

english, 2008

50

Synthesising protease-stable isopeptides by proteases: an efficient biocatalytic approach on the basis of a new type of substrate mimetics

Wehofsky, Nicole, Bordusa, Frank, Alisch, Mandy

Journal:

Chemical Communications

Year:

2001

Language:

english

File:

PDF, 44 KB

english, 2001