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51

Retinoids in Cancer Chemoprevention : Clinical Trials with the Synthetic Analogue Fenretinide

ALBERTO COSTA, GIUSEPPE DE PALO, ANDREA DECENSI, FRANCA FORMELLI, FAUSTO CHIESA, MAURIZIO NAVA, TIZIANA CAMERINI, ETTORE MARUBINI, UMBERTO VERONESI

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 931 KB

english, 1995

52

Chemoprevention of Breast Cancer with Fenretinide

Rosalba Torrisi, Dr Andrea Decensi, Franca Formelli, Tiziana Camerini, Giuseppe De Palo

Journal:

Year:

2001

Language:

english

File:

PDF, 193 KB

english, 2001

53

Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarian tumour cell line

Appierto, V, Cavadini, E, Pergolizzi, R, Cleris, L, Lotan, R, Canevari, S, Formelli, F

Journal:

British Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 96 KB

english, 2001

54

Prevention of local relapses and new localisations of oral leukoplakias with the synthetic retinoid fenretinide (4-HPR). Preliminary results

Chiesa, F., Tradati, N., Marazza, M., Rossi, N., Boracchi, P., Mariani, L., Clerici, M., Formelli, F., Barzan, L., Carrassi, A., Pastorini, A., Camerini, T., Giardini, R., Zurrida, S., Minn, F.L., Cos

Journal:

European Journal of Cancer Part B: Oral Oncology

Year:

1992

Language:

english

File:

PDF, 709 KB

english, 1992

55

Successful topical treatment of oral lichen planus and leukoplakias with fenretinide (4-HPR)

Tradati, Nicoletta, Chiesa, Fausto, Rossi, Nicoletta, Grigolato, Roberto, Formelli, Franca, Costa, Alberto, de Palo, Giuseppe

Journal:

Year:

1994

Language:

english

File:

PDF, 222 KB

english, 1994

56

Relation between waist circumference with others nutritional and inflammatory markers, in hemodialysis (hd) patients

Formelli, Franca, Zaccheo, Tiziana, Casazza, Anna Maria, Bellini, Ornella, Di Marco, Aurelio

Journal:

Journal of Renal Nutrition

Year:

2008

File:

PDF, 241 KB

2008

57

Effect of medroxyprogesterone acetate and doxorubicin on sublines of 13762 mammary adenocarcinoma in rats

Formelli, Franca, Zaccheo, Tiziana, Casazza, Anna Maria, Bellini, Ornella, Di Marco, Aurelio

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1981

Language:

english

File:

PDF, 2.51 MB

english, 1981

58

Effect of angiotensin II on the antitumor activity and cardiotoxicity of doxorubicin

Monti, E., Paracchini, L., Piccinini, F., Rossi, C., Formelli, F.

Journal:

Year:

1990

Language:

english

File:

PDF, 644 KB

english, 1990

59

Therapeutic effect of chemoimmunotherapy on lymphoma bearing mice

Formelli, F., Rossi, C., Sensi, M., Parmiani, G.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1987

Language:

english

File:

PDF, 118 KB

english, 1987

60

Distribution of fenretinide in the mammary gland of breast cancer patients

Mehta, Rajendra G., Moon, Richard C., Hawthorne, Michael, Formelli, Franca, Costa, Alberto

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1991

Language:

english

File:

PDF, 498 KB

english, 1991

61

Correlation between inhibitory effect on prolactin secretion and antitumor activity of new ergoline compounds on DMBA-induced tumors in rats

Formelli, Franca, Zaccheo, Tiziana, Di Salle, Enrico, Ornati, Giorgio, Di Marco, Aurelio

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1983

Language:

english

File:

PDF, 719 KB

english, 1983

62

Synthesis and antitumor properties of new glycosides of daunomycinone and adriamycinone

Arcamone, Federico, Penco, Sergio, Vigevani, Aristide, Redaelli, Silvio, Franchi, Giuliano, Di Marco, Aurelio, Casazza, Anna M., Dasdia, Teresa, Formelli, Franca

Journal:

Journal of Medicinal Chemistry

Year:

1975

Language:

english

File:

PDF, 594 KB

english, 1975

63

Plasma Testosterone and Prognosis of Postmenopausal Breast Cancer Patients

Micheli, A., Meneghini, E., Secreto, G., Berrino, F., Venturelli, E., Cavalleri, A., Camerini, T., Di Mauro, M. G., Cavadini, E., De Palo, G., Veronesi, U., Formelli, F.

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

64

Risks and Benefits of Retinoids in the Chemoprevention of Cancer

Dr Giuseppe De Palo,Franca Formelli

Journal:

Year:

1995

Language:

english

File:

PDF, 1.84 MB

english, 1995

65

Randomized Trial of Fenretinide to Prevent Second Breast Malignancy in Women With Early Breast Cancer

Veronesi, U., De Palo, G., Marubini, E., Costa, A., Formelli, F., Mariani, L., Decensi, A., Camerini, T., Del Turco, M. R., Di Mauro, M. G., Muraca, M. G., Del Vecchio, M., Pinto, C., D'Aiuto, G., Bon

Journal:

JNCI Journal of the National Cancer Institute

Year:

1999

Language:

english

File:

PDF, 207 KB

english, 1999

66

Altered Sphingolipid Metabolism inN-(4-Hydroxyphenyl)- retinamide-resistant A2780 Human Ovarian Carcinoma Cells

Prinetti, A., Basso, L., Appierto, V., Villani, M. G., Valsecchi, M., Loberto, N., Prioni, S., Chigorno, V., Cavadini, E., Formelli, F., Sonnino, S.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 742 KB

english, 2003

67

A Phase I-II Preoperative Biomarker Trial of Fenretinide in Ascitic Ovarian Cancer

Colombo, N., Formelli, F., Cantu, M. G., Parma, G., Gasco, M., Argusti, A., Santinelli, A., Montironi, R., Cavadini, E., Baglietto, L., Guerrieri-Gonzaga, A., Viale, G., Decensi, A.

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

68

Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity

Appierto, V., Tiberio, P., Cavadini, E., Casalini, P., Cappelletti, G., Formelli, F.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 601 KB

english, 2009

69

In Vivo Eradication of Human BCR/ABL-Positive Leukemia Cells With an ABL Kinase Inhibitor

le Coutre, P., Mologni, L., Cleris, L., Marchesi, E., Buchdunger, E., Giardini, R., Formelli, F., Gambacorti-Passerini, C.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1999

Language:

english

File:

PDF, 183 KB

english, 1999

70

IFN- Enhances the Antimyeloma Activity of the Fully Human Anti-Human Leukocyte Antigen-DR Monoclonal Antibody 1D09C3

Carlo-Stella, C., Guidetti, A., Di Nicola, M., Lavazza, C., Cleris, L., Sia, D., Longoni, P., Milanesi, M., Magni, M., Nagy, Z., Corradini, P., Carbone, A., Formelli, F., Gianni, A. M.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 414 KB

english, 2007

71

4-Oxo-Fenretinide, a Recently Identified Fenretinide Metabolite, Induces Marked G2-M Cell Cycle Arrest and Apoptosis in Fenretinide-Sensitive and Fenretinide-Resistant Cell Lines

Villani, M. G., Appierto, V., Cavadini, E., Bettiga, A., Prinetti, A., Clagett-Dame, M., Curley, R. W., Formelli, F.

Journal:

Cancer Research

Year:

2006

Language:

english

File:

PDF, 486 KB

english, 2006

72

AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

Petti, Carlotta, Vegetti, Claudia, Molla, Alessandra, Bersani, Ilaria, Cleris, Loredana, Mustard, Kirsty J., Formelli, Franca, Hardie, Grahame D., Sensi, Marialuisa, Anichini, Andrea

Journal:

Melanoma Research

Year:

2012

Language:

english

File:

PDF, 722 KB

english, 2012

73

In vitro and In vivo Activity of SKI-606, a Novel Src-Abl Inhibitor, against Imatinib-Resistant Bcr-Abl+ Neoplastic Cells

Puttini, M., Coluccia, A. M. L., Boschelli, F., Cleris, L., Marchesi, E., Donella-Deana, A., Ahmed, S., Redaelli, S., Piazza, R., Magistroni, V., Andreoni, F., Scapozza, L., Formelli, F., Gambacorti-P

Journal:

Cancer Research

Year:

2006

Language:

english

File:

PDF, 432 KB

english, 2006

74

Randomized Double-Blind 2 x 2 Trial of Low-Dose Tamoxifen and Fenretinide for Breast Cancer Prevention in High-Risk Premenopausal Women

Decensi, A., Robertson, C., Guerrieri-Gonzaga, A., Serrano, D., Cazzaniga, M., Mora, S., Gulisano, M., Johansson, H., Galimberti, V., Cassano, E., Moroni, S. M., Formelli, F., Lien, E. A., Pelosi, G.,

Journal:

Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 144 KB

english, 2009

75

Effect of Fenretinide and Low-Dose Tamoxifen on Insulin Sensitivity in Premenopausal Women at High Risk for Breast Cancer

Johansson, H., Gandini, S., Guerrieri-Gonzaga, A., Iodice, S., Ruscica, M., Bonanni, B., Gulisano, M., Magni, P., Formelli, F., Decensi, A.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 318 KB

english, 2008

76

Re: Vitamin A Analogue for Breast Cancer Prevention: a Grade of F or Incomplete?

Veronesi, U., De Palo, G., Marubini, E., Costa, A., Mariani, L., Formelli, F., Decensi, A.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2000

Language:

english

File:

PDF, 18 KB

english, 2000

77

Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of -Catenin, KRAS, and the Oncogenic Transcription Factor ITF2

Mologni, L., Dekhil, H., Ceccon, M., Purgante, S., Lan, C., Cleris, L., Magistroni, V., Formelli, F., Gambacorti-Passerini, C. B.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 892 KB

english, 2010

78

Role of impression cytology during hypovitaminosis A

Polizzi, A, Schenone, M, Sacca, S C, Burlando, S, Freedman, D, Marinari, G, Cuneo, S, Rovida, S, Formelli, F, Camerini, G

Journal:

British Journal of Ophthalmology

Year:

1998

Language:

english

File:

PDF, 156 KB

english, 1998

79

Plasma Retinol and Prognosis of Postmenopausal Breast Cancer Patients

Formelli, F., Meneghini, E., Cavadini, E., Camerini, T., Di Mauro, M. G., De Palo, G., Veronesi, U., Berrino, F., Micheli, A.

Journal:

Cancer Epidemiology Biomarkers & Prevention

Year:

2009

Language:

english

File:

PDF, 310 KB

english, 2009

80

Inhibition of RET tyrosine kinase by SU5416

Mologni, L., Sala, E., Cazzaniga, S., Rostagno, R., Kuoni, T., Puttini, M., Bain, J., Cleris, L., Redaelli, S., Riva, B., Formelli, F., Scapozza, L., Gambacorti-Passerini, C.

Journal:

Journal of Molecular Endocrinology

Year:

2006

Language:

english

File:

PDF, 419 KB

english, 2006

81

Effect of the Synthetic Retinoid Fenretinide on Dark Adaptation and the Ocular Surface

Decensi, A., Torrisi, R., Polizzi, A., Gesi, R., Brezzo, V., Rolando, M., Rondanina, G., AntoniettaOrengo, M., Formelli, F., Costa, A.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1994

Language:

english

File:

PDF, 646 KB

english, 1994

82

PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation

Appierto, V., Tiberio, P., Villani, M. G., Cavadini, E., Formelli, F.

Journal:

Year:

2009

Language:

english

File:

PDF, 546 KB

english, 2009

83

Can Fenretinide Protect Women Against Ovarian Cancer?

DE PALO, G., VERONESI, U., CAMERINI, T., FORMELLI, F., MASCOTTI, G., BONI, C., FOSSER, V., VECCHIO, M. D., CAMPA, T., COSTA, A., MARUBINI, E.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1995

Language:

english

File:

PDF, 185 KB

english, 1995

84

Comment re: Continuous Rather than Intermittent Administration of Fenretinide in Leukoplakia

Formelli, F., Cavadini, E., Appierto, V., Tiberio, P., Grigolato, R., Chiesa, F., Tradati, N., Persiani, S.

Journal:

Cancer Prevention Research

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

85

Characterization of compound 584, an Abl kinase inhibitor with lasting effects

Puttini, M., Redaelli, S., Moretti, L., Brussolo, S., Gunby, R. H, Mologni, L., Marchesi, E., Cleris, L., Donella-Deana, A., Drueckes, P., Sala, E., Lucchini, V., Kubbutat, M., Formelli, F., Zambon, A

Journal:

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

86

Retinoids: in vitro interaction with retinol-binding protein and influence on plasma retinol

Berni, R, Clerici, M, Malpeli, G, Cleris, L, Formelli, F

Journal:

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993

87

Pharmacokinetics and effects on plasma retinol concentrations of 13-cis-retinoic acid in melanoma patients

Formelli, F, Cavadini, E, Mascheroni, L, Belli, F, Cascinelli, N

Journal:

British Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 1.05 MB

english, 1997

88

In vivo characterization of a doxorubicin resistant B16 melanoma cell line

Formelli, F, Rossi, C, Supino, R, Parmiani, G

Journal:

British Journal of Cancer

Year:

1986

Language:

english

File:

PDF, 1.38 MB

english, 1986

89

Outcome of Conservatively Treated Microinvasive Squamous Cell Carcinoma of the Uterine Cervix During a 10-Year Follow-up

Costa, Silvano, Marra, Elena, Martinelli, Giuseppe N., Santini, Donatella, Casadio, Paolo, Formelli, Guido, Pelusi, Carla, Ghi, Tullio, Syrjänen, Kari, Pelusi, Giuseppe

Journal:

International Journal of Gynecological Cancer

Year:

2009

Language:

english

File:

PDF, 125 KB

english, 2009

90

ChemInform Abstract: SYNTHESIS AND ANTITUMOR PROPERTIES OF NEW GLYCOSIDES OF DAUNOMYCINONE AND ADRIAMYCINONE

ARCAMONE, F., PENCO, S., VIGEVANI, A., REDAELLI, S., FRANCHI, G., DI MARCO, A., CASAZZA, A. M., DASDIA, T., FORMELLI, F., NECCO, A., SORANZO, C.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 116 KB

1975

91

4-oxo-N-(4-hydroxyphenyl)retinamide: Two Independent Ways to Kill Cancer Cells

Tiberio, Paola, Cavadini, Elena, Abolafio, Gabriella, Formelli, Franca, Appierto, Valentina, Gartel, Andrei L.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.05 MB

english, 2010

92

Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl beta-glucuronide.

Formelli, F, Barua, A B, Olson, J A

Journal:

The FASEB Journal

Year:

1996

Language:

english

File:

PDF, 2.32 MB

english, 1996

93

Retinoids: in vitro interaction with retinol-binding protein and influence on plasma retinol.

Berni, R, Clerici, M, Malpeli, G, Cleris, L, Formelli, F

Journal:

The FASEB Journal

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993

94

Chemoprevention Trial of Contralateral Breast Cancer with Fenretinide. Rationale, Design, Methodology, Organization, Data Management, Statistics and Accrual

De Palo, Giuseppe, Camerini, Tiziana, Marubini, Ettore, Costa, Alberto, Formelli, Franca, Del Vecchio, Marcella, Mariani, Luigi, Miceli, Rosalba, Mascotti, Gustavo, Magni, Andrea, Campa, Tiziana, Di M

Journal:

Year:

1997

Language:

english

File:

PDF, 1.01 MB

english, 1997

95

Effect of Medroxyprogesterone Acetate and of Some Antiinflammatory Agents on Mouse Erythroleukemia Cell Differentiation

Supino, Rosanna, Mazzoni, Alessandra, Formelli, Franca

Journal:

Year:

1984

Language:

english

File:

PDF, 705 KB

english, 1984

96

Five-year administration of fenretinide: pharmacokinetics and effects on plasma retinol concentrations.

Formelli, F, Clerici, M, Campa, T, Di Mauro, M G, Magni, A, Mascotti, G, Moglia, D, De Palo, G, Costa, A, Veronesi, U

Journal:

Journal of Clinical Oncology

Year:

1993

File:

PDF, 605 KB

1993

97

Cardiac Calcified Amorphous Tumor as a Rare Cause of Ischemic Stroke

Formelli, Benedetta, Farina, Antonio, Pescini, Francesca, Palumbo, Vanessa, Grazia D’Alfonso, Maria, Oddo, Andrea, Mori, Fabio, Poggesi, Anna

Journal:

Circulation Cardiovascular Imaging

Year:

2020

File:

PDF, 163 KB

2020

98

Occurrence of resistance to retinoic acid in the acute promyelocytic leukemia cell line NB4 is associated with altered expression of the pml/RAR alpha protein

Dermime, S, Grignani, F, Clerici, M, Nervi, C, Sozzi, G, Talamo, GP, Marchesi, E, Formelli, F, Parmiani, G, Pelicci, PG, Gambacorti-Passerini, C

Journal:

Year:

1993

File:

PDF, 1.47 MB

1993

99

Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated bcl-2

Delia, D, Aiello, A, Formelli, F, Fontanella, E, Costa, A, Miyashita, T, Reed, JC, Pierotti, MA

Journal:

Year:

1995

File:

PDF, 1.93 MB

1995

100

Chronic oral administration of fenretinide, as a chemopreventive agent to breast cancer patients, does not affect plasma alpha-tocopherol concentration

Formelli, F., Clerici, M., De Palo, G., Costa, A., Veronesi, U.

Journal:

Annals of Oncology

Year:

1991

File:

PDF, 117 KB

1991