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51

Three new crystal structures of point mutation variants of mono TIM: conformational flexibility of loop-1, loop-4 and loop-8

Torben V Borchert, KV Radha Kishan, Johan Ph Zeelen, Wolfgang Schliebs, Narmada Thanki, Ruben Abagyan, Rainer Jaenicke, Rik K Wierenga

Journal:

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

52

The 2.8å Crystal Structure of peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae : a five-layered αβαβα structure constructed from two core domains of identical topology

M Mathieu, JPh Zeelen, RA Pauptit, R Erdmann, W-H Kunau, RK Wierenga

Journal:

Year:

1994

Language:

english

File:

PDF, 1.58 MB

english, 1994

53

Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant

Torben V. BORCHERT, Kathryn PRATT, Johan Ph. ZEELEN, Mia CALLENS, Martin E. M. NOBLE, Fred R. OPPERDOES, Paul A. M. MICHELS, Rik K. WIERENGA

Journal:

Year:

1993

Language:

english

File:

PDF, 968 KB

english, 1993

54

Steroid total synthesis

Journal:

Natural Product Reports

Year:

1994

Language:

english

File:

PDF, 643 KB

english, 1994

55

Selective Interaction of Glycosomal Enzymes from Trypanosoma brucei with Hydrophobic Cyclic Hexapeptides

M. Callens, J. Vanroy, J.P. Zeelen, T.V. Borchert, D. Nalis, R.K. Wierenga, F.R. Opperdoes

Journal:

Biochemical and Biophysical Research Communications

Year:

1993

File:

PDF, 325 KB

1993

56

The 1.8 Å crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism

Magali Mathieu, Yorgo Modis, Johan Ph Zeelen, Christian K Engel, Ruben A Abagyan, Anders Ahlberg, Bjarne Rasmussen, Victor S Lamzin, Wolf H Kunau, Rik K Wierenga

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 807 KB

english, 1997

57

Primary structure of elongation factor 1γ from Artemia

G.D.F. Maessen, R. Amons, J.P. Zeelen, W. Möller

Journal:

Year:

1987

Language:

english

File:

PDF, 357 KB

english, 1987

58

The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop

T.V. Borchert, M. Mathieu, J.Ph. Zeelen, S.A. Courtneidge, R.K. Wierenga

Journal:

Year:

1994

Language:

english

File:

PDF, 769 KB

english, 1994

59

An interface point-mutation variant of triosephosphate isomerase is compactly folded and monomeric at low protein concentrations

T.V. Borchert, J.Ph. Zeelen, W. Schliebs, M. Callens, W. Minke, R. Jaenicke, R.K. Wierenga

Journal:

Year:

1995

Language:

english

File:

PDF, 592 KB

english, 1995

60

Crystallization and preliminary X-ray diffraction studies of mitochondrial short-chain Δ3,Δ2-enoyl-CoA isomerase from rat liver

J.Ph. Zeelen, R.A. Pauptit, R.K. Wierenga, W.-H. Kunau, J.K. Hiltunen

Journal:

Journal of Molecular Biology

Year:

1992

Language:

english

File:

PDF, 311 KB

english, 1992

61

201. ENT-3-methoxy-16α-methylaminoestra-1,3,5(10)-trien-17β-ol hydrochloride, a selective anti-arrhythmic enantiosteroid

A. Boyd, M.B. Groen, B. Hindriksen, R.J. Marshall, T. Sleigh, E. Winslow, F.J. Zeelen

Journal:

Journal of Steroid Biochemistry

Year:

1982

Language:

english

File:

PDF, 86 KB

english, 1982

62

Determination of the affinity of a steroid for its receptor is not sufficient to measure its intrinsic hormonal activity

Journal:

Year:

1990

Language:

english

File:

PDF, 209 KB

english, 1990

63

Steroid research at Organon in the golden 1950s and the following years

S.A. Szpilfogel, F.J. Zeelen

Journal:

Year:

1996

Language:

english

File:

PDF, 1000 KB

english, 1996

64

The lock-and-key principle: Edited by J-P. Behr, Wiley, 1994. $85.00 (x + 325 pages) ISBN 0 471 93902 1

Journal:

Trends in Pharmacological Sciences

Year:

1995

Language:

english

File:

PDF, 142 KB

english, 1995

65

Strategy in drug reseabch. Synthesis and study of the psogestational and ovulation inhibitory activity of a series of 11β-substituted-17α-ethynyl-4-estren-17β-ols

A.J.v.d. Broek, A.I.A. Broess, M.J.v.d. Heuvel, H.P. de Jongh, J. Leemhuis, K.H. Schonemann, J. Smits, J. de Visser, N.P. van Vliet, F.J. Zeelen

Journal:

Year:

1977

Language:

english

File:

PDF, 1.44 MB

english, 1977

66

Ent-16α-methylamino-3-methoxy-1,3,5(10)-estratrien-17β-ol hydrochloride, a selective anti-arrhytmic enantiosteroid

A. Boyd, M.B. Groen, B. Hindriksen, R.J. Marshall, T. Sleigh, E. Winslow, F.J. Zeelen

Journal:

Year:

1982

Language:

english

File:

PDF, 635 KB

english, 1982

67

Structure and progestational activity of 13-substituted-18-norpregn-4-ene-3,20-diones, a pilot study

K.H. Schönemann, N.P. van Vliet, F.J. Zeelen

Journal:

Year:

1985

Language:

english

File:

PDF, 207 KB

english, 1985

68

Receptor models: learning from the progesterone receptor

Journal:

Trends in Pharmacological Sciences

Year:

1983

Language:

english

File:

PDF, 207 KB

english, 1983

69

Innovative approaches in drug research: The 3rd Noordwijkerhout Symposium, September 1985, Noordwijkerhout, The Netherlands

Journal:

Trends in Pharmacological Sciences

Year:

1985

Language:

english

File:

PDF, 236 KB

english, 1985

70

Molecular biological techniques make an impact on medicinal chemistry

Journal:

Trends in Pharmacological Sciences

Year:

1989

Language:

english

File:

PDF, 143 KB

english, 1989

71

New perspectives in histamine research: Noordwijkerhout, Netherlands, 6–8 July 1990

F.J. Zeelen, H. Timmerman

Journal:

Trends in Pharmacological Sciences

Year:

1990

Language:

english

File:

PDF, 214 KB

english, 1990

72

Comprehensive medicinal chemistry: edited by Corwin Hansch, Pergamon Press, 1990. $1995.00/£1145.00 (cii + 5494 pages in six volumes) ISBN 0 08 032530 0

H. Timmerman, A. Bast, H. Van der Goot, N.P.E. Vermeulen, F.J. Zeelen

Journal:

Trends in Pharmacological Sciences

Year:

1991

Language:

english

File:

PDF, 273 KB

english, 1991

73

Crystallographic studies of 3-ketoacylCoA thiolase from yeast Saccharomyces cerevisiae

J.Ph. Zeelen, R.K. Wierenga, R. Erdmann, W.-H. Kunau

Journal:

Journal of Molecular Biology

Year:

1990

Language:

english

File:

PDF, 246 KB

english, 1990

74

Conformational analysis of 20-keto steroids. Single-crystal X-ray structure analysis of 16α,17-epoxy-4-pregnene-3,20-dione

K. Goubitz, H. Schenk, F.J. Zeelen

Journal:

Year:

1984

Language:

english

File:

PDF, 165 KB

english, 1984

75

Early detection of metastases in melanoma patients by fine needle aspiration cyology

Voit, C., Mayer, T., Krupienski, M., Peter, R.U., Weber, L., Zeelen, U., Schoengen, A.

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 177 KB

english, 1998

76

Stereoselective synthesis of steroid side-chains

Redpath, J., Zeelen, F. J.

Journal:

Chemical Society Reviews

Year:

1983

Language:

english

File:

PDF, 980 KB

english, 1983

77

Stereoselective biomimetic total synthesis of 6.alpha.-methyl-19-norsteroids

Groen, Marinus B., Zeelen, Filippus J.

Journal:

Journal of Organic Chemistry

Year:

1978

Language:

english

File:

PDF, 563 KB

english, 1978

78

Modular mutagenesis of a TEM-barrel enzyme: the crystal structure of a chimeric E.coli TIM having the eighth βα-unit replaced by the equivalent unit of chicken TIM

Kishan, Radha, Zeelen, Ph. Johan, Noble, Martin E.M., Borchert, Torben V., Mainfroid, Véronique, Goraj, Karine, Martial, Joseph A., Wierenga, Rik K.

Journal:

Protein Engineering Design and Selection

Year:

1994

Language:

english

File:

PDF, 3.09 MB

english, 1994

79

Biomimetic polyene cyclizations. Total synthesis of dl-19-nor-4-pregnen-20-one. Asymmetric induction by the initiating center

Peters, Jacobus A. M., Posthumus, Tonny A. P., Van Vliet, Nicolaas P., Zeelen, Filippus J., Johnson, William S.

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 1017 KB

english, 1980

80

[IEEE 2001 IEEE Autotestcon Processing. IEEE Systems Readiness Technology Conference - Valley Forge, PA, USA (20-23 Aug. 2001)] 2001 IEEE Autotestcon Proceedings. IEEE Systems Readiness Technology Conference. (Cat. No.01CH37237) - PROMIS methodology for prognostic health management

Smeulers, J.P.M., Zeelen, R., Bos, A.

Year:

2001

Language:

english

File:

PDF, 557 KB

english, 2001

81

‘I felt very bad, I had self-rejection’: narratives of exclusion and marginalisation among early school leavers in Uganda

Tukundane, Cuthbert, Zeelen, Jacques, Minnaert, Alexander, Kanyandago, Peter

Journal:

Journal of Youth Studies

Year:

2014

Language:

english

File:

PDF, 185 KB

english, 2014

82

Adult education in the Limpopo province of South Africa: challenges for policy implementation

zeelen, j., rampedi, m., de jong, g.

Journal:

International Journal of Lifelong Education

Year:

2011

Language:

english

File:

PDF, 198 KB

english, 2011

83

Capacity building in Southern Africa: experiences and reflections: towards joint knowledge production and social change in international development cooperation

Zeelen, Jacques, van der Linden, Josje

Journal:

Year:

2009

Language:

english

File:

PDF, 98 KB

english, 2009

84

Technical and economic results from forced moulting of laying hens

Zeelen, Ir. H. H. M.

Journal:

World's Poultry Science Journal

Year:

1975

Language:

english

File:

PDF, 516 KB

english, 1975

85

Triose-phosphate Isomerase (TIM) of the Psychrophilic BacteriumVibrio marinus: KINETIC AND STRUCTURAL PROPERTIES

Alvarez, M., Zeelen, J. P., Mainfroid, V., Rentier-Delrue, F., Martial, J. A., Wyns, L., Wierenga, R. K., Maes, D.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 777 KB

english, 1998

86

Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power

Williams, J. C., Zeelen, J. P., Neubauer, G., Vriend, G., Backmann, J., Michels, P. A.M., Lambeir, A.-M., Wierenga, R. K.

Journal:

Protein Engineering Design and Selection

Year:

1999

Language:

english

File:

PDF, 314 KB

english, 1999

87

Protein engineering with monomeric triosephosphate isomerase (monoTIM): the modelling and structure verification of a seven-residue loop

Thanki, N., Zeelen, J. P., Mathieu, M., Jaenicke, R., Abagyan, R. A., Wierenga, R. K., Schliebs, W.

Journal:

Protein Engineering Design and Selection

Year:

1997

Language:

english

File:

PDF, 622 KB

english, 1997

88

A review of enabling factors in support intervention programmes for early school leavers: What are the implications for Sub-Saharan Africa?

Tukundane, Cuthbert, Minnaert, Alexander, Zeelen, Jacques, Kanyandago, Peter

Journal:

Children and Youth Services Review

Year:

2015

Language:

english

File:

PDF, 341 KB

english, 2015

89

[Principles of Medical Biology] Molecular and Cellular Pharmacology Volume 8 || Chapter 22 Medicinal Chemistry of steroids

Year:

1997

Language:

english

File:

PDF, 1.30 MB

english, 1997

90

[IEEE 2002 IEEE Aerospace Conference - Big Sky, MT, USA (9-16 March 2002)] Proceedings, IEEE Aerospace Conference - PROMIS - A generic PHM methodology applied to aircraft subsystems

Smeulers, J.P.M., Zeelen, R., Bos, A.

Year:

2002

Language:

english

File:

PDF, 585 KB

english, 2002

91

Beyond silence and rumor

Zeelen, Jacques, Wijbenga, Hieke, Vintges, Marga, de Jong, Gideon

Journal:

Health Education

Year:

2010

Language:

english

File:

PDF, 202 KB

english, 2010

92

Using participatory action research to improve vocational skills training for marginalised youth in Uganda: experiences from an early school-leavers’ project

Tukundane, Cuthbert, Zeelen, Jacques

Journal:

International Journal of Training Research

Year:

2015

Language:

english

File:

PDF, 338 KB

english, 2015

93

Die Feinnadelaspirationszytologie malignomverdächtiger Lymphknoten: Diagnostischer Wert und Fähigkeit zur Vorhersage der Histogenese

Schoengen, A., Binder, T., Fembacher, P., Zeelen, U.

Journal:

DMW - Deutsche Medizinische Wochenschrift

Year:

1995

File:

PDF, 1.64 MB

1995

94

Motivations for participation in higher education: narratives of non-traditional students at Makerere University in Uganda

Tumuheki, Peace Buhwamatsiko, Zeelen, Jacques, Openjuru, George Ladaah

Journal:

International Journal of Lifelong Education

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

95

Beyond Care Avoidance and Care Paralysis: Theorizing Public Mental Health Care

Schout, G., de Jong, G., Zeelen, J.

Journal:

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

96

SPIE Proceedings [SPIE 1985 International Technical Symposium/Europe - Cannes, France (Monday 25 November 1985)] Architectures and Algorithms for Digital Image Processing III - A Hardware Design For Fast 2-D Percentile Filtering

Duin, R. P. W., Haringa, H., Zeelen, R., Corbett, Francis J., Siegel, Howard J., Duff, Michael J.

Year:

1986

Language:

english

File:

PDF, 146 KB

english, 1986

97

ChemInform Abstract: Biomimetic Total Synthesis of Steroids. Part 10. Synthesis of 7-(Methoxymethyl)- and 7-(Phenylmethoxymethyl)-19-norsteroids.

GROEN, M. B., ZEELEN, F. J.

Journal:

Year:

1987

File:

PDF, 215 KB

1987

98

ChemInform Abstract: Steroid Total Synthesis

GROEN, M. B., ZEELEN, F. J.

Journal:

Year:

1987

File:

PDF, 91 KB

1987

99

High-resolution transmission electron microscopy with an electrostatic Zach phase plate

Hettler, S, Dries, M, Zeelen, J, Oster, M, Schröder, R R, Gerthsen, D

Journal:

New Journal of Physics

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

100

ChemInform Abstract: A Partial Synthesis of 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Desogestrel) Based Upon Intramolecular Oxidation of an 11β-Hydroxy-19-norsteroid to the 18 → 11β-Lactone.

VAN DEN HEUVEL, M. J., VAN BOKHOVEN, C. W., DE JONGH, H. P., ZEELEN, F. J.

Journal:

Year:

1988

File:

PDF, 175 KB

1988