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1

5-HT4 Receptor Ligands: Applications and New Prospects

Michel Langlois, Rodolphe Fischmeister

Journal:

Year:

2003

File:

PDF, 51 KB

2003

2

Cardiovascular effects of Urtica dioica L. in isolated rat heart and aorta

Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham, Abdelhafid Tahri, Mohamed Serhrouchni, Jacqueline Hoerter, Rodolphe Fischmeister

Journal:

Phytotherapy Research

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

3

A loudspeaker-driven system for rapid and multiple solution exchanges in patch-clamp experiments

Pierre-François Méry, Patrick Lechêne, Rodolphe Fischmeister

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1992

Language:

english

File:

PDF, 791 KB

english, 1992

4

Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase

Méry, Pierre-François, Brechler, Véronique, Pavoine, Catherine, Pecker, Françoise, Fischmeister, Rodolphe

Journal:

Year:

1990

File:

PDF, 430 KB

1990

5

Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block

Pierre Eftekhari, Laurent Sallé, Frank Lezoualc'h, Jeanne Mialet, Monique Gastineau, Jean-Paul Briand, David A. Isenberg, Gilbert J. Fournié, Jorge Argibay, Rodolphe Fischmeister, Sylviane Muller, Joh

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 136 KB

english, 2000

6

Induction of neonatal lupus in pups of mice immunized with synthetic peptides derived from amino acid sequences of the serotoninergic 5-HT4 receptor

Pierre Eftekhari, Jean-Christophe Roegel, Frank Lezoualc'h, Rodolphe Fischmeister, Jean-Louis Imbs, Johan Hoebeke

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 246 KB

english, 2001

7

Cloning, Expression, and Pharmacology of Four Human 5-Hydroxytryptamine4 Receptor Isoforms Produced by Alternative Splicing in the Carboxyl Terminus

Olivier Blondel, Monique Gastineau, Yamina Dahmoune, Michel Langlois, Rodolphe Fischmeister

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.13 MB

english, 1998

8

Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4receptor and its consequences in early BALB/c mouse embryonic development

Rehab Kamel, Simone Garcia, Frank Lezoualc'h, Rodolphe Fischmeister, Sylviane Muller, Johan Hoebeke, Pierre Eftekhari

Journal:

BMC Developmental Biology

Year:

2007

Language:

english

File:

PDF, 3.24 MB

english, 2007

9

PDE2 and PDE5 exert specific and distinct roles in regulating cGMP signals elicited by particulate or soluble guanylyl cyclases in rat cardiac myocytes

Liliana Castro, Grégoire Vandecasteele, Rodolphe Fischmeister

Journal:

BMC Pharmacology

Year:

2005

Language:

english

File:

PDF, 200 KB

english, 2005

10

Opposite effects of cGMP-dependent protein kinase on cGMP production by soluble and particular guanylyl cyclase in adult ventricular myocytes

Liliana Castro, Rodolphe Fischmeister

Journal:

BMC Pharmacology

Year:

2007

Language:

english

File:

PDF, 192 KB

english, 2007

11

cGMP compartments in cardiac myocytes

Rodolphe Fischmeister, Liliana Castro

Journal:

BMC Pharmacology

Year:

2007

Language:

english

File:

PDF, 189 KB

english, 2007

12

Arbutus unedo induces endothelium-dependent relaxation of the isolated rat aorta

Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham, Abdelhafid Tahri, Abdelkhaleq Legssyer, Jacqueline Hoerter, Rodolphe Fischmeister

Journal:

Phytotherapy Research

Year:

2002

Language:

english

File:

PDF, 104 KB

english, 2002

13

Tannins and catechin gallate mediate the vasorelaxant effect of Arbutus unedo on the rat isolated aorta

Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekhﬁ, Mohamed Bnouham, Christine Herrenknecht, Vincent Roumy, Christophe Fourneau, Alain Laurens, Jacqueline Hoerter, Rodolphe Fischmeister

Journal:

Phytotherapy Research

Year:

2004

Language:

english

File:

PDF, 208 KB

english, 2004

14

Cyclic GMP regulates the Ca-channel current in guinea pig ventricular myocytes

Renzo C. Levi, Giuseppe Alloatti, Rodolphe Fischmeister

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1989

Language:

english

File:

PDF, 374 KB

english, 1989

15

Some limitations of the cell-attached patch clamp technique: a two-electrode analysis

Rodolphe Fischmeister, Richard K. Ayer, Robert L. DeHaan

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1986

Language:

english

File:

PDF, 1.21 MB

english, 1986

16

Longitudinal distribution of Na+ and Ca2+ channels and β-adrenoceptors on the sarcolemmal membrane of frog cardiomyocytes

Jonas Jurevičius, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

1997

Language:

english

File:

PDF, 379 KB

english, 1997

17

Role of the NO-cGMP pathway in the muscarinic regulation of the L-type Ca2+ current in human atrial myocytes

Grégoire Vandecasteele, Thomas Eschenhagen, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

1998

Language:

english

File:

PDF, 538 KB

english, 1998

18

Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart

Jean-Michel Chesnais, Rodolphe Fischmeister, Pierre-François Méry

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 294 KB

english, 1999

19

Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart

Jean-Michel Chesnais, Rodolphe Fischmeister, Pierre-François Méry

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 680 KB

english, 1999

20

Local response of L-type Ca2+ current to nitric oxide in frog ventricular myocytes

Michael Dittrich, Jonas Jurevičius, Marie Georget, Francesca Rochais, Bernd Kurt Fleischmann, Jürgen Hescheler, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 429 KB

english, 2001

21

Simultaneous measurements of intracellular cAMP and L-type Ca2+ current in single frog ventricular myocytes

Jean-Marc Goaillard, Pierre Vincent, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 1.74 MB

english, 2001

22

G protein-mediated inhibitory effect of a nitric oxide donor on the L-type Ca2+ current in rat ventricular myocytes

Najah Abi-Gerges, Rodolphe Fischmeister, Pierre-François Méry

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 342 KB

english, 2001

23

Cyclic GMP regulation of the L-type Ca2+ channel current in human atrial myocytes

Grégoire Vandecasteele, Ignacio Verde, Catherine Rücker-Martin, Patrick Donzeau-Gouge, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 321 KB

english, 2001

24

Role of cyclic nucleotide phosphodiesterase isoforms in cAMP compartmentation following β2-adrenergic stimulation of ICa,L in frog ventricular myocytes

Jonas Jurevicius, V. Arvydas Skeberdis, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

2003

Language:

english

File:

PDF, 307 KB

english, 2003

25

Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

Hartzell, H. Criss, Fischmeister, Rodolphe

Journal:

Year:

1986

File:

PDF, 331 KB

1986

26

Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation

Hartzell, H. Criss, Méry, Pierre-Francois, Fischmeister, Rodolphe, Szabo, Gabor

Journal:

Year:

1991

File:

PDF, 505 KB

1991

27

10.1038/6553

Fischmeister, Rodolphe, Vandecasteele, Grégoire, Eschenhagen, Thomas, Scholz, Hasso, Stein, Birgitt, Verde, Ignacio

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 164 KB

english, 1999

28

Crosstalk between Rap1 and Rac regulates secretion of sAPPα

Maillet, Marjorie, Robert, Sylvain J., Cacquevel, Mathias, Gastineau, Monique, Vivien, Denis, Bertoglio, Jacques, Zugaza, José L., Fischmeister, Rodolphe, Lezoualc'h, Frank

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 1.42 MB

english, 2003

29

A comparative study of the effects of three guanylyl cyclase inhibitors on the L-type Ca2+ and muscarinic K+ currents in frog cardiac myocytes

Najah Abi-Gerges, Leif Hove-Madsen, Rodolphe Fischmeister, Pierre-François Méry

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 447 KB

english, 1997

30

Pharmacological characterization of the receptors involved in the β-adrenoceptor-mediated stimulation of the L-type Ca2+ current in frog ventricular myocytes

V Arvydas Skeberdis, Jonas Jurevičius, Rodolphe Fischmeister

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 420 KB

english, 1997

31

The 5-HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5-HT4(c) receptor

Olivier Blondel, Monique Gastineau, Michel Langlois, Rodolphe Fischmeister

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 227 KB

english, 1998

32

Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L-type Ca2+ current in rat ventricular myocytes

Ignacio Verde, Grégoire Vandecasteele, Frank Lezoualc'h, Rodolphe Fischmeister

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 224 KB

english, 1999

33

Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines

Jeanne Mialet, Isabelle Berque-Bestel, Pierre Eftekhari, Monique Gastineau, Mireille Giner, Yamina Dahmoune, Patrick Donzeau-Gouge, Johan Hoebeke, Michel Langlois, Sames Sicsic, Rodolphe Fischmeister,

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 324 KB

english, 2000

34

Exploration of the ligand binding site of the human 5-HT4 receptor by site-directed mutagenesis and molecular modeling

Jeanne Mialet, Yamina Dahmoune, Frank Lezoualc'h, Isabelle Berque-Bestel, Pierre Eftekhari, Johan Hoebeke, Sames Sicsic, Michel Langlois, Rodolphe Fischmeister

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 324 KB

english, 2000

35

Pharmacological characterization of the human 5-HT4(d) receptor splice variant stably expressed in Chinese hamster ovary cells

Jeanne Mialet, Isabelle Berque-Bestel, Sames Sicsic, Michel Langlois, Rodolphe Fischmeister, Frank Lezoualc'h

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 206 KB

english, 2000

36

Characterization of human 5-HT4(d) receptor desensitization in CHO cells

Jeanne Mialet, Rodolphe Fischmeister, Frank Lezoualc'h

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

37

New insights into the human 5-HT4 receptor binding site: exploration of a hydrophobic pocket

Lucie Rivail, Mireille Giner, Monique Gastineau, Magali Berthouze, Jean-Louis Soulier, Rodolphe Fischmeister, Frank Lezoualc'h, Bernard Maigret, Sames Sicsic, Isabelle Berque-Bestel

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 405 KB

english, 2004

38

NO donors potentiate the β-adrenergic stimulation of ICa,L and the muscarinic activation of IK,ACh in rat cardiac myocytes

Najah Abi-Gerges, Gabor Szabo, Angela S. Otero, Rodolphe Fischmeister, Pierre-François Méry

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 561 KB

english, 2002

39

Functional expression of the hyperpolarization-activated, non-selective cation current If in immortalized HL-1 cardiomyocytes

Laura Sartiani, Pascal Bochet, Elisabetta Cerbai, Alessandro Mugelli, Rodolphe Fischmeister

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 519 KB

english, 2002

40

Volume sensitivity of the bestrophin family of chloride channels

Rodolphe Fischmeister, H. Criss Hartzell

Journal:

The Journal of Physiology

Year:

2005

Language:

english

File:

PDF, 456 KB

english, 2005

41

The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes

Laetitia Pereira, Mélanie Métrich, María Fernández-Velasco, Alexandre Lucas, Jérôme Leroy, Romain Perrier, Eric Morel, Rodolphe Fischmeister, Sylvain Richard, Jean-Pierre Bénitah, Frank Lezoualc'h, An

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 613 KB

english, 2007

42

Post-translational modifications of cardiac tubulin during chronic heart failure in the rat

Souad Belmadani, Christian Poüs, Renée Ventura-Clapier, Rodolphe Fischmeister, Pierre-François Méry

Journal:

Molecular and Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 170 KB

english, 2002

43

Post-translational modifications of tubulin and microtubule stability in adult rat ventricular myocytes and immortalized HL-1 cardiomyocytes

Souad Belmadani, Christian Poüs, Rodolphe Fischmeister, Pierre-François Méry

Journal:

Molecular and Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 592 KB

english, 2004

44

A comparative analysis of the time course of cardiac Ca2+current response to rapid applications of β-adrenergic and dihydropyridine agonists

Pierre-François Méry, A. Michael Frace, H. Criss Hartzell, Rodolphe Fischmeister

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.08 MB

english, 1993

45

Species- and tissue-dependent effects of NO and cyclic GMP on cardiac ion channels

Rodolphe Fischmeister, Liliana Castro, Aniella Abi-Gerges, Francesca Rochais, Grégoire Vandecasteele

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2005

Language:

english

File:

PDF, 153 KB

english, 2005

46

A new regulation of IL-6 production in adult cardiomyocytes by β-adrenergic and IL-1β receptors and induction of cellular hypertrophy by IL-6 trans-signalling

Nicolas Szabo-Fresnais, Florence Lefebvre, Aurore Germain, Rodolphe Fischmeister, Martine Pomérance

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

47

Design and Synthesis of Specific Probes for Human 5-HT4 Receptor Dimerization Studies

Soulier, Jean-Louis, Russo, Olivier, Giner, Mireille, Rivail, Lucie, Berthouze, Magali, Ongeri, Sandrine, Maigret, Bernard, Fischmeister, Rodolphe, Lezoualc'h, Frank, Sicsic, Sames

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 347 KB

english, 2005

48

Sympathetic Modulation of the Effect of Nifedipine on Myocardial Contraction and Ca Current in the Rat

AbdelKhaleq Legssyer, Leif Hove-Madsen, Jacqueline Hoerter, Rodolphe Fischmeister

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1997

Language:

english

File:

PDF, 356 KB

english, 1997

49

Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization

Magali Berthouze, Lucie Rivail, Alexandre Lucas, Mohammed A. Ayoub, Olivier Russo, Sames Sicsic, Rodolphe Fischmeister, Isabelle Berque-Bestel, Ralf Jockers, Frank Lezoualc’h

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 297 KB

english, 2007

50

Quantitative mRNA analysis of serotonin 5-HT4 receptor isoforms, calcium handling proteins and ion channels in human atrial fibrillation

Frank Lezoualc’h, Klaudia Steplewski, Laura Sartiani, Alessandro Mugelli, Rodolphe Fischmeister, Antoine Bril

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 201 KB

english, 2007