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51

cGMP-dependent protein kinase Iα associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake

Jennifer A Steiner, Ana Marin D Carneiro, Jane Wright, Heinrich JG Matthies, Harish C Prasad, Christian K Nicki, Wolfgang R Dostmann, Carrie C Buchanan, Jackie D Corbin, Sharron H Francis, Randy D Bla

Journal:

Molecular Brain

Year:

2009

Language:

english

File:

PDF, 1.77 MB

english, 2009

52

[Handbook of Experimental Pharmacology] Phosphodiesterases as Drug Targets Volume 204 || Pharmacology, Clinical Efficacy, and Tolerability of Phosphodiesterase-4 Inhibitors: Impact of Human Pharmacokinetics

Francis, Sharron H., Conti, Marco, Houslay, Miles D.

Year:

2011

Language:

english

File:

PDF, 429 KB

english, 2011

53

Amino-Acid Sequence of the Variable Region of the Heavy (Alpha) Chain of a Mouse Myeloma Protein with Anti-Hapten Activity

Sharron H. Francis, R. Graham Q. Leslie, Leroy Hood and Herman N. Eisen

Journal:

Proceedings of the National Academy of Sciences

Year:

1974

Language:

english

File:

PDF, 696 KB

english, 1974

54

Histidine-607 and Histidine-643 Provide Important Interactions for Metal Support of Catalysis in Phosphodiesterase-5 †

Francis, Sharron H., Turko, Illarion V., Grimes, Kennard A., Corbin, Jackie D.

Journal:

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000

55

Distinguishing between Closely Related Protein Kinases: A Variation on the Bisubstrate Inhibitor Theme

Yan, Xiongwei, Lawrence, David S., Corbin, Jackie D., Francis, Sharron H.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 69 KB

english, 1996

56

Effects of photooxidation of histidine-38 on the various catalytic activities of glyceraldehyde 3-phosphate dehydrogenase

Francis, Sharron H., Meriwether, Blanche P., Park, Jane Harting

Journal:

Year:

1973

Language:

english

File:

PDF, 2.83 MB

english, 1973

57

N-Terminal Domain of Phosphodiesterase-11A4 (PDE11A4) Decreases Affinity of the Catalytic Site for Substrates and Tadalafil, and is Involved in Oligomerization †

Weeks, James L., Zoraghi, Roya, Francis, Sharron H., Corbin, Jackie D.

Journal:

Year:

2007

Language:

english

File:

PDF, 289 KB

english, 2007

58

Distinguishing between A Mitogenic and Two Closely Related Nonmitogenic Protein Kinases

Yan, Xiongwei, Lawrence, David S., Corbin, Jackie D., Francis, Sharron H.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 77 KB

english, 1996

59

Effects of photooxidation of histidine-38 on the acetylphosphatase activity of glyceraldehyde 3-phosphate dehydrogenase

Francis, Sharron H., Meriwether, Blanche P., Park, Jane Harting

Journal:

Year:

1973

Language:

english

File:

PDF, 603 KB

english, 1973

60

Hydropathic Analysis and Mutagenesis of the Catalytic Domain of the cGMP-Binding cGMP-Specific Phosphodiesterase (PDE5). cGMP versus cAMP Substrate Selectivity †

Turko, Illarion V., Francis, Sharron H., Corbin, Jackie D.

Journal:

Year:

1998

Language:

english

File:

PDF, 71 KB

english, 1998

61

Sildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction

Francis, Sharron H, Corbin, Jackie D

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2005

Language:

english

File:

PDF, 341 KB

english, 2005

62

Sildenafil citrate does not affect cardiac contractility in human or dog heart

Corbin, Jackie, Rannels, Stephen, Neal, Doss, Chang, Paul, Grimes, Kennard, Beasley, Alfreda, Francis, Sharron

Journal:

Current Medical Research and Opinion

Year:

2003

Language:

english

File:

PDF, 355 KB

english, 2003

63

Deletion of the nef Gene Abrogates the Ability of SIVsmmPBj to Induce Acutely Lethal Disease in Pigtail Macaques

NOVEMBRE, FRANCIS J., LEWIS, MARK G., SAUCIER, M. MICHELLE, YALLEY-OGUNRO, JACOB, BRENNAN, TERRY, McKINNON, KATHARINE, BELLAH, SHARRON, McCLURE, HAROLD M.

Journal:

AIDS Research and Human Retroviruses

Year:

1996

Language:

english

File:

PDF, 1.70 MB

english, 1996

64

Isolated Regulatory Domains of cGMP-dependent Protein Kinase Iα and Iβ Retain Dimerization and Native cGMP-binding Properties and Undergo Isoform-specific Conformational Changes

Richie-Jannetta, Robyn, Busch, Jennifer L., Higgins, Kristin A., Corbin, Jackie D., Francis, Sharron H.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 879 KB

english, 2006

65

[Methods in Enzymology] Initiation and Termination of Cyclic Nucleotide Action Volume 159 || [65] Purification of cGMP-binding protein phosphodiesterase from rat lung

Francis, Sharron H.

Year:

1988

Language:

english

File:

PDF, 1.19 MB

english, 1988

66

Cyclic Nucleotide Phosphodiesterases in Health and Disease || Pde9

Francis, Sharron, Beavo, Joseph, Houslay, Miles

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

67

cGMP-dependent protein kinase protects cGMP from hydrolysis by phosphodiesterase-5

KOTERA, Jun, GRIMES, Kennard A., CORBIN, Jackie D., FRANCIS, Sharron H.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 164 KB

english, 2003

68

Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation

TURKO, V. Illarion, FRANCIS, H. Sharron, CORBIN, D. Jackie

Journal:

Biochemical Journal

Year:

1998

Language:

english

File:

PDF, 344 KB

english, 1998

69

Cyclic Nucleotide Phosphodiesterases in Health and Disease || Medicinal Chemistry of PDE4 Inhibitors

Francis, Sharron, Beavo, Joseph, Houslay, Miles

Year:

2006

Language:

english

File:

PDF, 265 KB

english, 2006

70

[Methods in Enzymology] Protein Phosphorylation Part A: Protein Kinases: Assays, Purification, Antibodies, Functional Analysis, Cloning, and Expression Volume 200 || [26] Purification of type Iα and Type Iβ isozymes and proteolyzed type Iβ monomeric enzyme of cGMP-dependent protein kinase from bovine aorta

Francis, Sharron H.

Year:

1991

Language:

english

File:

PDF, 909 KB

english, 1991

71

[Advances in Pharmacology] Volume 26 || Progress in Understanding the Mechanism and Function of Cyclic GhAP-Dependent Protein Kinase

Francis, Sharron H.

Year:

1994

Language:

english

File:

PDF, 3.34 MB

english, 1994

72

Calcineurin Regulates Homologous Desensitization of Natriuretic Peptide Receptor-A and Inhibits ANP-Induced Testosterone Production in MA-10 Cells

Henesy, Michelle B., Britain, Andrea L., Zhu, Bing, Amable, Lauren, Honkanen, Richard E., Corbin, Jackie D., Francis, Sharron H., Rich, Thomas C., Hetman, Michal

Journal:

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

73

Potential Roles of Conserved Amino Acids in the Catalytic Domain of the cGMP-binding cGMP-specific Phosphodiesterase (PDE5)

Turko, Illarion V., Francis, Sharron H., Corbin, Jackie D.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 158 KB

english, 1998

74

Handbook of Cell Signaling || Phosphodiesterase-5

Francis, Sharron H.

Year:

2010

Language:

english

File:

PDF, 257 KB

english, 2010

75

Molecular properties of mammalian proteins that interact with cGMP: protein kinases, cation channels, phosphodiesterases, and multi-drug anion transporters

Francis, Sharron, H.

Journal:

Frontiers in Bioscience

Year:

2005

Language:

english

File:

PDF, 443 KB

english, 2005

76

Mechanisms of autoinhibition in cyclic nucleotide-dependent protein kinases

Francis, Sharron, H.

Journal:

Frontiers in Bioscience

Year:

2002

Language:

english

File:

PDF, 623 KB

english, 2002

77

ANF elicits phosphorylation of the cGMP phosphodiesterase in vascular smooth muscle cells

Wyatt, Todd A., Naftilan, Allen J., Francis, Sharron H., Corbin, Jackie D.

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

78

Mechanisms of autoinhibition in cyclic nucleotide-dependent protein kinases

Francis, Sharron H

Journal:

Frontiers in Bioscience

Year:

2002

File:

PDF, 623 KB

2002