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1

Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant

Folcher, Marc, Oesterle, Sabine, Zwicky, Katharina, Thekkottil, Thushara, Heymoz, Julie, Hohmann, Muriel, Christen, Matthias, Daoud El-Baba, Marie, Buchmann, Peter, Fussenegger, Martin

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

2

The Growth Factor Inhibitor Suramin Reduces Apoptosis and Cell Aggregation in Protein-Free CHO Cell Batch Cultures

James A. Zanghi, Wolfgang A. Renner, James E. Bailey, Martin Fussenegger

Journal:

Biotechnology Progress

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

3

Engineering synergy in biotechnology

Nielsen, Jens, Fussenegger, Martin, Keasling, Jay, Lee, Sang Yup, Liao, James C, Prather, Kristala, Palsson, Bernhard

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 489 KB

english, 2014

4

Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice

Shao, Jiawei, Xue, Shuai, Yu, Guiling, Yu, Yuanhuan, Yang, Xueping, Bai, Yu, Zhu, Sucheng, Yang, Linfeng, Yin, Jianli, Wang, Yidan, Liao, Shuyong, Guo, Sanwei, Xie, Mingqi, Fussenegger, Martin, Ye, Ha

Journal:

Science Translational Medicine

Year:

2017

Language:

english

File:

PDF, 3.12 MB

english, 2017

5

Use of antibodies for detection of phosphorylated proteins separated by two-dimensional gel electrophoresis

Hitto Kaufmann, James E. Bailey, Martin Fussenegger

Journal:

Year:

2001

Language:

english

File:

PDF, 86 KB

english, 2001

6

Ectopic expression of human mTOR increases viability, robustness, cell size, proliferation, and antibody production of chinese hamster ovary cells

Imke A.J. Dreesen, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

7

G Protein–Coupled Receptors Revisited: Therapeutic Applications Inspired by Synthetic Biology

Heng, Boon Chin, Aubel, Dominique, Fussenegger, Martin

Journal:

Annual Review of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

8

From gene switches to mammalian designer cells: present and future prospects

Ausländer, Simon, Fussenegger, Martin

Journal:

Trends in Biotechnology

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

9

[Methods in Molecular Medicine™] Tissue Engineering Volume 140 || Small Blood Vessel Engineering

Hauser, Hansjörg, Fussenegger, Martin

Year:

2007

Language:

english

File:

PDF, 565 KB

english, 2007

10

Synthetic Biology: Innovative approaches for pharmaceutics and drug delivery

Deans, Tara L., Grainger, David W., Fussenegger, Martin

Journal:

Advanced Drug Delivery Reviews

Year:

2016

Language:

english

File:

PDF, 126 KB

english, 2016

11

Programmable full-adder computations in communicating three-dimensional cell cultures

Ausländer, David, Ausländer, Simon, Pierrat, Xavier, Hellmann, Leon, Rachid, Leila, Fussenegger, Martin

Journal:

Year:

2017

Language:

english

File:

PDF, 550 KB

english, 2017

12

Designing cell function: assembly of synthetic gene circuits for cell biology applications

Xie, Mingqi, Fussenegger, Martin

Journal:

Nature Reviews Molecular Cell Biology

Year:

2018

Language:

english

File:

PDF, 43.85 MB

english, 2018

13

Optogenetic Medicine: Synthetic Therapeutic Solutions Precision-Guided by Light

Ye, Haifeng, Fussenegger, Martin

Journal:

Cold Spring Harbor Perspectives in Medicine

Year:

2018

Language:

english

File:

PDF, 3.37 MB

english, 2018

14

p27Kip1-mediated controlled proliferation technology increases constitutive sICAM production in CHO-DUKX adapted for growth in suspension and serum-free media

Heiko Meents, Barbara Enenkel, Rolf G. Werner, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 141 KB

english, 2002

15

Metabolic engineering II. Eukaryotic systems

Martin Fussenegger, Michael J. Betenbaugh

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 871 KB

english, 2002

16

BioLogic gates enable logical transcription control in mammalian cells

Beat P. Kramer, Cornelius Fischer, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

2004

Language:

english

File:

PDF, 780 KB

english, 2004

17

Heat-stable oral alga-based vaccine protects mice from Staphylococcus aureus infection

Imke A.J. Dreesen, Ghislaine Charpin-El Hamri, Martin Fussenegger

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 614 KB

english, 2010

18

Detailed design and comparative analysis of protocols for optimized production of high-performance HIV-1-derived lentiviral particles

Barbara Mitta, Markus Rimann, Martin Fussenegger

Journal:

Metabolic Engineering

Year:

2005

Language:

english

File:

PDF, 364 KB

english, 2005

19

Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells

Marcel Tigges, Martin Fussenegger

Journal:

Metabolic Engineering

Year:

2006

Language:

english

File:

PDF, 308 KB

english, 2006

20

Macrolide-based transgene control in mammalian cells and mice

Weber, Wilfried, Fux, Cornelia, Daoud-El Baba, Marie, Keller, Bettina, Weber, Cornelia C., Kramer, Beat P., Heinzen, Christoph, Aubel, Dominique, Bailey, James E., Fussenegger, Martin

Journal:

Nature Biotechnology

Year:

2002

Language:

english

File:

PDF, 1.95 MB

english, 2002

21

An engineered epigenetic transgene switch in mammalian cells

Kramer, Beat P, Viretta, Alessandro Usseglio, Baba, Marie Daoud-El, Aubel, Dominique, Weber, Wilfried, Fussenegger, Martin

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 166 KB

english, 2004

22

A novel system for trigger-controlled drug release from polymer capsules

David A. Fluri, Christian Kemmer, Marie Daoud-El Baba, Martin Fussenegger

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

23

Synthetic two-way communication between mammalian cells

Bacchus, William, Lang, Moritz, El-Baba, Marie Daoud, Weber, Wilfried, Stelling, Jörg, Fussenegger, Martin

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 738 KB

english, 2012

24

SAMY, a novel mammalian reporter gene derived from Bacillus stearothermophilus α-amylase

Stefan Schlatter, Markus Rimann, Jens Kelm, Martin Fussenegger

Journal:

Year:

2002

Language:

english

File:

PDF, 564 KB

english, 2002

25

[Methods in Molecular Biology] Synthetic Gene Networks Volume 813 || Expressed Protein Modifications: Making Synthetic Proteins

Weber, Wilfried, Fussenegger, Martin

Year:

2012

Language:

english

File:

PDF, 391 KB

english, 2012

26

Synthetic mammalian gene circuits for biomedical applications

Ye, Haifeng, Aubel, Dominique, Fussenegger, Martin

Journal:

Current Opinion in Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.40 MB

english, 2013

27

[ESACT Proceedings] Animal Cell Technology Meets Genomics Volume 2 || An Efficient Approach to Cell Culture Medium Optimization — A Statistical Method to Medium Mixing

Gòdia, Francesc, Fussenegger, Martin

Year:

2005

Language:

english

File:

PDF, 439 KB

english, 2005

28

[Cell Engineering] Systems Biology Volume 5 || Metabolic Flux Analysis of Mammalian Cells

Al-Rubeai, Mohamed, Fussenegger, Martin

Year:

2007

Language:

english

File:

PDF, 300 KB

english, 2007

29

Animal Cell Technology Meets Genomics || Design of an Animal Protein Free Medium to Sustain Vero Cells Growth in a Stirred Tank Bioreactor

Gòdia, Francesc, Fussenegger, Martin

Year:

2005

Language:

english

File:

PDF, 146 KB

english, 2005

30

Mammalian designer cells: Engineering principles and biomedical applications

Xie, Mingqi, Fussenegger, Martin

Journal:

Biotechnology Journal

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

31

Synthetic biology: applying biological circuits beyond novel therapies

Dobrin, Anton, Saxena, Pratik, Fussenegger, Martin

Journal:

Integrative Biology

Year:

2016

Language:

english

File:

PDF, 4.11 MB

english, 2016

32

In vitro assays for anticancer drug discovery???a novel approach based on engineered mammalian cell lines

Gonzalez-Nicolini, Valeria, Fussenegger, Martin

Journal:

Anti-Cancer Drugs

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

33

Self-adjusting synthetic gene circuit for correcting insulin resistance

Ye, Haifeng, Xie, Mingqi, Xue, Shuai, Hamri, Ghislaine Charpin-El, Yin, Jianli, Zulewski, Henryk, Fussenegger, Martin

Journal:

Nature Biomedical Engineering

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

34

Synthetic biology – Engineering cell-based biomedical devices

Haellman, Viktor, Fussenegger, Martin

Journal:

Current Opinion in Biomedical Engineering

Year:

2017

Language:

english

File:

PDF, 3.49 MB

english, 2017

35

The new frontiers of synthetic biology

Tullman-Ercek, Danielle, Fussenegger, Martin

Journal:

Current Opinion in Systems Biology

Year:

2017

Language:

english

File:

PDF, 168 KB

english, 2017

36

Treatment of chronic pain by designer cells controlled by spearmint aromatherapy

Wang, Hui, Xie, Mingqi, Charpin-El Hamri, Ghislaine, Ye, Haifeng, Fussenegger, Martin

Journal:

Nature Biomedical Engineering

Year:

2018

Language:

english

File:

PDF, 2.61 MB

english, 2018

37

Synthetic biology-based cellular biomedical tattoo for detection of hypercalcemia associated with cancer

Tastanova, Aizhan, Folcher, Marc, Müller, Marius, Camenisch, Gieri, Ponti, Aaron, Horn, Thomas, Tikhomirova, Maria S., Fussenegger, Martin

Journal:

Science Translational Medicine

Year:

2018

Language:

english

File:

PDF, 584 KB

english, 2018

38

Programming mammalian gene expression with the antibiotic simocyclinone D8 and the flavonoid luteolin

Bojar, Daniel, Fussenegger, Martin

Journal:

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

39

From synthetic biology to human therapy: engineered mammalian cells

Scheller, Leo, Fussenegger, Martin

Journal:

Current Opinion in Biotechnology

Year:

2019

Language:

english

File:

PDF, 1.20 MB

english, 2019

40

Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice

Krawczyk, Krzysztof, Xue, Shuai, Buchmann, Peter, Charpin-El-Hamri, Ghislaine, Saxena, Pratik, Hussherr, Marie-DidiÃ©e, Shao, Jiawei, Ye, Haifeng, Xie, Mingqi, Fussenegger, Martin

Journal:

Year:

2020

File:

PDF, 1.43 MB

2020

41

A novel cytostatic process enhances the productivity of Chinese hamster ovary cells

Martin Fussenegger, Xenia Mazur, James E. Bailey

Journal:

Biotechnology and Bioengineering

Year:

1997

Language:

english

File:

PDF, 288 KB

english, 1997

42

pTRIDENT, a novel vector family for tricistronic gene expression in mammalian cells

Martin Fussenegger, Xenia Mazur, James E. Bailey

Journal:

Biotechnology and Bioengineering

Year:

1998

Language:

english

File:

PDF, 280 KB

english, 1998

43

Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells

Hitto Kaufmann, Xenia Mazur, Martin Fussenegger, James E. Bailey

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 383 KB

english, 1999

44

Serum protects protein-free competent Chinese hamster ovary cells against apoptosis induced by nutrient deprivation in batch culture

James A. Zanghi, Martin Fussenegger, James E. Bailey

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 790 KB

english, 1999

45

A novel autoregulated proliferation-controlled production process using recombinant CHO cells

Xenia Mazur, Hans M. Eppenberger, James E. Bailey, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 111 KB

english, 1999

46

Comparative analysis of two controlled proliferation strategies regarding product quality, influence on tetracycline-regulated gene expression, and productivity

Hitto Kaufmann, Xenia Mazur, Romina Marone, James E. Bailey, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

2001

Language:

english

File:

PDF, 407 KB

english, 2001

47

A Gene Therapy Technology-Based Biomaterial for the Trigger-Inducible Release of Biopharmaceuticals in Mice

Michael M. Kämpf, Erik H. Christen, Martin Ehrbar, Marie Daoud-El Baba, Ghislaine Charpin-El Hamri, Martin Fussenegger, Wilfried Weber

Journal:

Advanced Functional Materials

Year:

2010

Language:

english

File:

PDF, 270 KB

english, 2010

48

Conditional DNA-Protein Interactions Confer Stimulus-Sensing Properties to Biohybrid Materials

Erik H. Christen, Maria Karlsson, Michael M. Kämpf, Ronald Schoenmakers, Raphael J. Gübeli, Hanna M. Wischhusen, Christian Friedrich, Martin Fussenegger, Wilfried Weber

Journal:

Advanced Functional Materials

Year:

2011

Language:

english

File:

PDF, 726 KB

english, 2011

49

Mammalian synthetic biology – from tools to therapies

Dominique Aubel, Martin Fussenegger

Journal:

Year:

2010

Language:

english

File:

PDF, 831 KB

english, 2010

50

Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-xL on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media

Heiko Meents, Barbara Enenkel, Hans M. Eppenberger, Rolf G. Werner, Martin Fussenegger

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 380 KB

english, 2002