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1

Studies on the toxicity of Punica granatum L. (Punicaceae) whole fruit extracts

Alexis Vidal, Adyary Fallarero, Blanca R Peña, Maria E Medina, Bienvenido Gra, Felicia Rivera, Yamilet Gutierrez, Pia M Vuorela

Journal:

Journal of Ethnopharmacology

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

2

Antioxidant Activity of Phenolics Compounds From Sugar Cane (Saccharum officinarumL.) Juice

Joaquim Maurício Duarte-Almeida, Alexis Vidal Novoa, Adyary Fallarero Linares, Franco M. Lajolo, Maria Inés Genovese

Journal:

Plant Foods for Human Nutrition

Year:

2006

Language:

english

File:

PDF, 236 KB

english, 2006

3

Staphylococcus aureus biofilm susceptibility to small and potent β 2,2 -amino acid derivatives

Ausbacher, Dominik, Fallarero, Adyary, Kujala, Janni, Määttänen, Anni, Peltonen, Jouko, Strøm, Morten B., Vuorela, Pia M.

Journal:

Year:

2014

Language:

english

File:

PDF, 769 KB

english, 2014

4

Preparation, characterization and antimicrobial application of hybrid cellulose-lignin beads

Gabov, Konstantin, Oja, Terhi, Deguchi, Takahiro, Fallarero, Adyary, Fardim, Pedro

Journal:

Year:

2017

Language:

english

File:

PDF, 3.21 MB

english, 2017

5

Screening of Natural Product Derivatives Identifies Two Structurally Related Flavonoids as Potent Quorum Sensing Inhibitors against Gram-Negative Bacteria

Manner, Suvi, Fallarero, Adyary

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 2.81 MB

english, 2018

6

Flavones as Quorum Sensing Inhibitors Identified by a Newly Optimized Screening Platform Using Chromobacterium violaceum as Reporter Bacteria

Skogman, Malena, Kanerva, Sonja, Manner, Suvi, Vuorela, Pia, Fallarero, Adyary

Journal:

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

7

Molecular Docking Guided Comparative GFA, G/PLS, SVM and ANN Models of Structurally Diverse Dual Binding Site Acetylcholinesterase Inhibitors

Shikhar Gupta, Adyary Fallarero, Mikko J. Vainio, P. Saravanan, J. Santeri Puranen, Päivi Järvinen, Mark S. Johnson, Pia M. Vuorela, C. Gopi Mohan

Journal:

Molecular Informatics

Year:

2011

Language:

english

File:

PDF, 552 KB

english, 2011

8

Potency determinations of acetylcholinesterase inhibitors using Ellman’s reaction-based assay in screening: Effect of assay variants

Päivi Järvinen, Pia Vuorela, Annele Hatakka, Adyary Fallarero

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 222 KB

english, 2011

9

Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with β-amyloid, acetylcholine, and butyrylcholine esterases

Vildan Alptüzün, Michaela Prinz, Verena Hörr, Josef Scheiber, Krzysztof Radacki, Adyary Fallarero, Pia Vuorela, Bernd Engels, Holger Braunschweig, Ercin Erciyas, Ulrike Holzgrabe

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

10

Discovery of dual binding site acetylcholinesterase inhibitors identified by pharmacophore modeling and sequential virtual screening techniques

Shikhar Gupta, Adyary Fallarero, Päivi Järvinen, Daniela Karlsson, Mark S. Johnson, Pia M. Vuorela, C. Gopi Mohan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 960 KB

english, 2011

11

Effect of high concentration of Co (II) on Enterobacter liquefaciens strain C-1: A bacterium highly resistant to heavy metals with an unknown genome.

Jeannette Marrero, Luis Javier González, Aniel Sánchez, Marta Ayala, Dalila Paz-Lago, Wendy González, Adyary Fallarero, Lila Castellanos-Serra, Orquídea Coto

Journal:

Year:

2004

Language:

english

File:

PDF, 305 KB

english, 2004

12

Homogeneous Screening Assay for Human Tankyrase

Narwal, M., Fallarero, A., Vuorela, P., Lehtio, L.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 567 KB

english, 2012

13

Coumarins permeability in Caco-2 cell model

Anna Galkin, Adyary Fallarero, Professor Pia M. Vuorela

Journal:

Journal of Pharmacy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

14

Screening against Staphylococcus aureus biofilms using a 96-microtiter well plates assay: An automated approach

A. Fallarero, M. Sandberg, A. Määttänen, J. Peltonen, P. Vuorela

Journal:

European Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

15

Identification and characterization of diarylimidazoles as hybrid inhibitors of butyrylcholinesterase and amyloid beta fibril formation

Daniela Karlsson, Adyary Fallarero, Gerda Brunhofer, Przemyslaw Guzik, Michaela Prinz, Ulrike Holzgrabe, Thomas Erker, Pia Vuorela

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 544 KB

english, 2012

16

The exploration of thienothiazines as selective butyrylcholinesterase inhibitors

Daniela Karlsson, Adyary Fallarero, Gerda Brunhofer, Claudia Mayer, Ohm Prakash, C. Gopi Mohan, Pia Vuorela, Thomas Erker

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 3.52 MB

english, 2012

17

Effects of the aqueous extract of Bryothamnion triquetrum on chemical hypoxia and aglycemia-induced damage in GT1-7 mouse hypothalamic immortalized cells

A. Fallarero, A. Peltoketo, J. Loikkanen, P. Tammela, A. Vidal, P. Vuorela

Journal:

Year:

2006

Language:

english

File:

PDF, 256 KB

english, 2006

18

Alpha- and β-casein components of host milk induce biofilm formation in the mastitis bacterium Streptococcus uberis

Emilia Varhimo, Pekka Varmanen, Adyary Fallarero, Malena Skogman, Satu Pyörälä, Antti Iivanainen, Antti Sukura, Pia Vuorela, Kirsi Savijoki

Journal:

Veterinary Microbiology

Year:

2011

Language:

english

File:

PDF, 607 KB

english, 2011

19

Effects of aqueous extracts of Halimeda incrassata (Ellis) Lamouroux and Bryothamnion triquetrum (S.G.Gmelim) Howe on hydrogen peroxide and methyl mercury-induced oxidative stress in GT1-7 mouse hypothalamic immortalized cells

A. Fallarero, J.J. Loikkanen, P.T. Männistö, O. Castañeda, A. Vidal

Journal:

Year:

2003

Language:

english

File:

PDF, 129 KB

english, 2003

20

Pros and cons of using resazurin staining for quantification of viable Staphylococcus aureus biofilms in a screening assay

Malena E. Sandberg, Denise Schellmann, Gerda Brunhofer, Thomas Erker, Igor Busygin, Reko Leino, Pia M. Vuorela, Adyary Fallarero

Journal:

Journal of Microbiological Methods

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

21

Living Cells of Staphylococcus aureus Immobilized onto the Capillary Surface in Electrochromatography: A Tool for Screening of Biofilms

Chen, Jie, Fallarero, Adyary, Määttänen, Anni, Sandberg, Malena, Peltonen, Jouko, Vuorela, Pia M., Riekkola, Marja-Liisa

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 827 KB

english, 2008

22

Combining biofilm matrix measurements with biomass and viability assays in susceptibility assessments of antimicrobials against Staphylococcus aureus biofilms

Skogman, Malena Elise, Vuorela, Pia Maarit, Fallarero, Adyary

Journal:

The Journal of Antibiotics

Year:

2012

Language:

english

File:

PDF, 502 KB

english, 2012

23

Inhibition of acetylcholinesterase by coumarins: The case of coumarin 106

Adyary Fallarero, Päivi Oinonen, Shikhar Gupta, Pia Blom, Anna Galkin, C. Gopi Mohan, Pia M. Vuorela

Journal:

Pharmacological Research

Year:

2008

Language:

english

File:

PDF, 513 KB

english, 2008

24

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: The case of chelerythrine

Gerda Brunhofer, Adyary Fallarero, Daniela Karlsson, Ana Batista-Gonzalez, Pravin Shinde, C. Gopi Mohan, Pia Vuorela

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 879 KB

english, 2012

25

Automating a 96-well microtitre plate model for Staphylococcus aureus biofilms: an approach to screening of natural antimicrobial compounds

Malena Sandberg, Anni Määttänen, Jouko Peltonen, Pia M. Vuorela, Adyary Fallarero

Journal:

International Journal of Antimicrobial Agents

Year:

2008

Language:

english

File:

PDF, 635 KB

english, 2008

26

Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors

Venkannagari, Harikanth, Fallarero, Adyary, Feijs, Karla L.H., Lüscher, Bernhard, Lehtiö, Lari

Journal:

European Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 820 KB

english, 2013

27

Screening and Structural Analysis of Flavones Inhibiting Tankyrases

Narwal, Mohit, Haikarainen, Teemu, Fallarero, Adyary, Vuorela, Pia M., Lehtiö, Lari

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

28

1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood–brain barrier

Prinz, Michaela, Parlar, Sülünay, Bayraktar, Gülşah, Alptüzün, Vildan, Erciyas, Ercin, Fallarero, Adyary, Karlsson, Daniela, Vuorela, Pia, Burek, Malgorzata, Förster, Carola, Turunc, Ezgi, Armagan, Gu

Journal:

European Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 657 KB

english, 2013

29

Towards fabrication of 3D printed medical devices to prevent biofilm formation

Sandler, Niklas, Salmela, Ida, Fallarero, Adyary, Rosling, Ari, Khajeheian, Mohammad, Kolakovic, Ruzica, Genina, Natalja, Nyman, Johan, Vuorela, Pia

Journal:

International Journal of Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 498 KB

english, 2014

30

High-throughput screening with a miniaturized radioligand competition assay identifies new modulators of human α2-adrenoceptors

Fallarero, Adyary, Pohjanoksa, Katariina, Wissel, Gloria, Parkkisenniemi-Kinnunen, Ulla-Mari, Xhaard, Henri, Scheinin, Mika, Vuorela, Pia

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

31

Printed paper-based arrays as substrates for biofilm formation

Määttänen, Anni, Fallarero, Adyary, Kujala, Janni, Ihalainen, Petri, Vuorela, Pia, Peltonen, Jouko

Journal:

Year:

2014

Language:

english

File:

PDF, 3.35 MB

english, 2014

32

Revisiting an agar-based plate method: What the static biofilm method can offer for biofilm research

Oja, Terhi, Blomqvist, Brianna, Buckingham-Meyer, Kelli, Goeres, Darla, Vuorela, Pia, Fallarero, Adyary

Journal:

Journal of Microbiological Methods

Year:

2014

Language:

english

File:

PDF, 377 KB

english, 2014

33

Liposomes-in-Hydrogel Delivery System with Mupirocin: In Vitro Antibiofilm Studies and In Vivo Evaluation in Mice Burn Model

Hurler, Julia, Sørensen, Karen K., Fallarero, Adyary, Vuorela, Pia, Škalko-Basnet, Nataša

Journal:

BioMed Research International

Year:

2013

Language:

english

File:

PDF, 741 KB

english, 2013

34

(+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro

Fallarero, Adyary, Skogman, Malena, Kujala, Janni, Rajaratnam, Mohanathas, Moreira, Vânia, Yli-Kauhaluoma, Jari, Vuorela, Pia

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 432 KB

english, 2013

35

How to Translate a Bioassay Into a Screening Assay for Natural Products: General Considerations and Implementation of Antimicrobial Screens

Fallarero, Adyary, Hanski, Leena, Vuorela, Pia

Journal:

Year:

2014

Language:

english

File:

PDF, 534 KB

english, 2014

36

Systematic Exploration of Natural and Synthetic Flavonoids for the Inhibition of Staphylococcus aureus Biofilms

Manner, Suvi, Skogman, Malena, Goeres, Darla, Vuorela, Pia, Fallarero, Adyary

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 509 KB

english, 2013

37

New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcusaureus and effectively disrupt bacterial membrane integrity

Manner, Suvi, Vahermo, Mikko, Skogman, Malena E., Krogerus, Sara, Vuorela, Pia M., Yli-Kauhaluoma, Jari, Fallarero, Adyary, Moreira, Vânia M.

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 835 KB

english, 2015

38

Effective anti-biofilm polyketides against Staphylococcus aureus from the pyranonaphthoquinone biosynthetic pathways of Streptomyces species

Oja, Terhi, San Martin Galindo, Paola, Taguchi, Takaaki, Manner, Suvi, Vuorela, Pia M., Ichinose, Koji, Metsä-Ketelä, Mikko, Fallarero, Adyary

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 826 KB

english, 2015

39

GT1-7 Cell-Based cytoxicity screening assay on 96-well microplates as a platform for the safety assessment of genetically modified Gerbera hybrida extracts

Fallarero, Adyary, Ainasoja, Miia, Sandberg, Malena, Teeri, Teemu H., Vuorela, Pia M.

Journal:

Drug and Chemical Toxicology

Year:

2009

Language:

english

File:

PDF, 557 KB

english, 2009

40

Protein and bacterial interactions with nanostructured polymer coatings

Juvonen, Helka, Oja, Terhi, Määttänen, Anni, Sarfraz, Jawad, Rosqvist, Emil, Riihimäki, Tiina A., Toivakka, Martti, Kulomaa, Markku, Vuorela, Pia, Fallarero, Adyary, Peltonen, Jouko, Ihalainen, Petri

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2015

Language:

english

File:

PDF, 2.15 MB

english, 2015

41

Phenotypic screening identifies protein synthesis inhibitors as H-ras-nanocluster increasing tumor growth inducers

Kaja Najumudeen, Arafath, Posada, Itziar MD, Lectez, Benoit, Zhou, Yong, Landor, Sebastian K-J, Fallarero, Adyary, Vuorela, Pia Maarit, Hancock, John F., Abankwa, Daniel

Journal:

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

42

Penicillin G increases the synthesis of a suicidal marker (CidC) and virulence (HlgBC) proteins in Staphylococcus aureus biofilm cells

Savijoki, Kirsi, Skogman, Malena, Fallarero, Adyary, Nyman, Tuula A., Sukura, Antti, Vuorela, Pia, Varmanen, Pekka

Journal:

International Journal of Medical Microbiology

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

43

Bioactive glass combined with bisphosphonates provides protection against biofilms formed by the periodontal pathogen Aggregatibacter actinomycetemcomitans

Hiltunen, Anna K., Skogman, Malena E., Rosenqvist, Kirsi, Juvonen, Helka, Ihalainen, Petri, Peltonen, Jouko, Juppo, Anne, Fallarero, Adyary

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

44

Miniaturization and Validation of the Ellmans Reaction Based Acetylcholinesterase Inhibitory Assay into 384-Well Plate Format and Screening of a Chemical Library

Jarvinen, Paivi, Fallarero, Adyary, Gupta, Shikhar, Mohan, Gobi, Hatakka, Annele, Vuorela, Pia

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2010

Language:

english

File:

PDF, 314 KB

english, 2010

45

Neuroprotective effects of Halimeda incrassata and Bryothamnium triquetrum aqueous extracts on in vitro models of oxidative stress

Fallarero, A., Loikkanen, J., Castaneda, O., Vidal, A., Mannisto, P.

Journal:

Biochemical Society Transactions

Year:

2000

Language:

english

File:

PDF, 88 KB

english, 2000

46

Synthesis and biological evaluation of 8-hydroxy-2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)

Schiedel, M., Fallarero, A., Luise, C., Sippl, W., Vuorela, P., Jung, M.

Journal:

Year:

2017

Language:

english

File:

PDF, 1015 KB

english, 2017

47

Luminometric Nanoparticle-Based Assay for High Sensitivity Detection of β-Amyloid Aggregation

Pihlasalo, Sari, Deguchi, Takahiro, Virtamo, Maria, Jacobino, Jenna, Chary, Karthik, López-Picón, Francisco R., Brunhofer-Bolzer, Gerda, Huttunen, Roope, Fallarero, Adyary, Vuorela, Pia, Härmä, Harri

Journal:

Analytical Chemistry

Year:

2017

Language:

english

File:

PDF, 2.12 MB

english, 2017

48

Prevention of Staphylococcus aureus biofilm formation by antibiotics in 96-Microtiter Well Plates and Drip Flow Reactors: critical factors influencing outcomes

Manner, Suvi, Goeres, Darla M., Skogman, Malena, Vuorela, Pia, Fallarero, Adyary

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

49

Bisphosphonates offer protection against prosthetic joint infections caused by Staphylococcus aureus and Staphylococcus epidermidis biofilms

Hiltunen, Anna K., Vuorela, Pia M., Fallarero, Adyary

Journal:

Journal of Drug Delivery Science and Technology

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

50

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Skogman, Malena E., Vuorela, Pia M., Fallarero, Adyary

Journal:

Journal of Visualized Experiments

Year:

2016

Language:

english

File:

PDF, 453 KB

english, 2016

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