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51

ChemInform Abstract: Conformationally Restricted Analogues of Methionine: Synthesis of Chiral 3-Amino-5-methylthio-2-piperidones.

R. RODRIGUEZ, M. A. ESTIARTE, A. DIEZ, M. RUBIRALTA, A. COLELL, C. GARCIA-RUIZ, J. C. FERNANDEZ-CHECA

Journal:

Year:

1996

File:

PDF, 32 KB

1996

52

Qualitative and Quantitative Changes in Skeletal Muscle mtDNA and Expression of Mitochondrial-Encoded Genes in the Human Aging Process

Antoni Barrientos, Jordi Casademont, Francesc Cardellach, Esther Ardite, Xavier Estivill, Alvaro Urbano-Márquez, J.Carlos Fernández-Checa, Virginia Nunes

Journal:

Biochemical and Molecular Medicine

Year:

1997

Language:

english

File:

PDF, 232 KB

english, 1997

53

P-227 Increased sinusoidal efflux and decreased excretion of bile acids by the inhibition of binding to the cytosol Y' bile acid binders (BAB)

H Takikawa, Y Sugiyama, J.C Fernandez-Checa, N Kaplowitz, M Yamanaka

Journal:

International Hepatology Communications

Year:

1995

Language:

english

File:

PDF, 127 KB

english, 1995

54

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

Joan Montero, Montserrat Mari, Anna Colell, Albert Morales, Gorka Basañez, Carmen Garcia-Ruiz, Jose C. Fernández-Checa

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2010

Language:

english

File:

PDF, 822 KB

english, 2010

55

Mitochondrial cholesterol and cell death

José C. Fernández-Checa

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2010

Language:

english

File:

PDF, 53 KB

english, 2010

56

Chronic Ethanol Feeding Induces Cellular Antioxidants Decrease and Oxidative Stress in Rat Peripheral Nerves. Effect of S-Adenosyl-l-Methionine and N-Acetyl-l-Cysteine

Francisco Bosch-Morell, Francisco Martı́nez-Soriano, Anna Colell, J.Carlos Fernández-Checa, Francisco J Romero

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 146 KB

english, 1998

57

A Simple Technique to Determine Glutathione (GSH) Levels and Synthesis in Ocular Tissues as GSH-bimane Adduct: Application to Normal and Galactosemic Guinea-pigs

Ram Kannan, Diana Tang, Jasmina B. Mackic, Berislav V. Zlokovic, Jose C. Fernandez-Checa

Journal:

Experimental Eye Research

Year:

1993

File:

PDF, 358 KB

1993

58

Effect of indomethacin on the uptake, metabolism and excretion of 3-oxocholic acid: Studies in isolated hepatocytes and perfused rat liver

H. Takikawa, J.C. Fernandez-Checa, J. Kuhlenkamp, A. Stolz, M. Ookhtens, N. Kaplowitz

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1991

Language:

english

File:

PDF, 368 KB

english, 1991

59

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

Montserrat Marí, Francisco Caballero, Anna Colell, Albert Morales, Juan Caballeria, Anna Fernandez, Carlos Enrich, José C. Fernandez-Checa, Carmen García-Ruiz

Journal:

Cell Metabolism

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

60

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

Francisco Caballero, Anna Fernández, Antonio M. De Lacy, Jose C. Fernández-Checa, Juan Caballería, Carmen García-Ruiz

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 691 KB

english, 2009

61

Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia–reperfusion injury

Laura Llacuna, Anna Fernández, Claudia Von Montfort, Núria Matías, Laura Martínez, Francisco Caballero, Antoni Rimola, Montserrat Elena, Albert Morales, José C. Fernández-Checa, Carmen García-Ruiz

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 2.20 MB

english, 2011

62

Reply to: “2′,7′-Dichlorofluorescein is not a probe for the detection of reactive oxygen and nitrogen species”

Albert Morales, Carmen Garcia-Ruiz, Jose C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 170 KB

english, 2012

63

Systemic effects of cigarette smoke exposure in the guinea pig

Esther Ardite, Víctor I. Peinado, Roberto A. Rabinovich, José C. Fernández-Checa, Josep Roca, Joan A. Barberà

Journal:

Respiratory Medicine

Year:

2006

Language:

english

File:

PDF, 297 KB

english, 2006

64

Glutathione Depletion Impairs Myogenic Differentiation of Murine Skeletal Muscle C2C12 Cells through Sustained NF-κB Activation

Esther Ardite, Joan Albert Barbera, Josep Roca, Jose C. Fernández-Checa

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 529 KB

english, 2004

65

Redox regulation and signaling lipids in mitochondrial apoptosis

José C. Fernández-Checa

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 169 KB

english, 2003

66

Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-α-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation: Possible role of ganglioside GD3

Anna Colell, Albert Morales, José C Fernández-Checa, Carmen Garcı́a-Ruiz

Journal:

Year:

2002

Language:

english

File:

PDF, 360 KB

english, 2002

67

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-κB activation and apoptosis in human colon HT-29 cells

Anna Colell, Olga Coll, Montse Marı́, José C Fernández-Checa, Carmen Garcı́a-Ruiz

Journal:

Year:

2002

Language:

english

File:

PDF, 322 KB

english, 2002

68

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

Anna Colell, Carmen Garcı́a-Ruiz, Montserrat Mari, José C Fernández-Checa

Journal:

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

69

Transcriptional regulation of the heavy subunit chain of γ-glutamylcysteine synthetase by ionizing radiation

Albert Morales, Merce Miranda, Alberto Sanchez-Reyes, Anna Colell, Albert Biete, José C Fernández-Checa

Journal:

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

70

90 Hepatic mitochondrial free cholesterol accumulation in the Niemann-pick C disease

M. Mari, F. Caballero, A. Colell, C. Garcia-Ruiz, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006

71

283 Hepatocellular cholesterol distribution in Ob/Ob mice and its role in non-alcoholic steatohepatitis

E. Caballero, M. Mari, A. Colell, C. Garcia-Ruiz, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 131 KB

english, 2006

72

[41] ACIDIC SPHINGOMYELINASE IS REQUIRED FOR TNF-INDUCED MITOCHONDRIAL PERMEABILIZATION AND HEPATOCELLULAR DEATH VIA CARDIOLIPIN PEROXIDATION

M. Mari, A. Colell, C. Garcia-Ruiz, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 268 KB

english, 2007

73

[286] BIFUNCTIONAL ROLE OF MITOCHONDRIAL REACTIVE OXYGEN SPECIES IN DETERMINING THE SURVIVAL/SUSCEPTIBILITY OF HEPATOMA CELLS TO HYPOXIA

J.M. Lluis, A. Morales, C. Blasco, A. Colell, M. Mari, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 152 KB

english, 2007

74

[333] ACIDIC SPHINGOMYELINASE REGULATES THE FIBROGENIC POTENTIAL OF HEPATIC STELLATE CELLS

A. Moles, J.C. Fernandez-Checa, M. Mari

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 151 KB

english, 2007

75

159 GAS6 PROTECTS AGAINST HEPATIC ISCHEMIA/REPERFUSION INJURY THROUGH AKT ACTIVATION

L. Llacuna, D. Bellido, P. Garcia de Frutos, J.C. Fernandez-Checa, A. Morales

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

76

160 SELECTIVE ACTIVATION OF PROTECTIVE NF-KB DEPENDENT GENES BY S-ADENOSYLMETHIONINE REDUCES ISCHEMIA/REPERFUSION INJURY IN MOUSE LIVER

L. Llacuna, A. Morales, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

77

426 INHIBITION OF THE SQUALENE SYNTHASE OR STAR SILENCING INCREASES THE SUSCEPTIBILITY OF HEPATOCELLULAR CARCINOMA TO CHEMOTHERAPY

J. Montero, A. Morales, L. Llacuna, J.M. Lluis, C. Garcia-Ruiz, A. Colell, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

78

481 CATHEPSINS B AND D PLAY A CRITICAL ROLE IN HSC ACTIVATION

A. Moles, J.C. Fernandez-Checa, M. Mari

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

79

916 ENHANCED SREBP-2 EXPRESSION AND FREE CHOLESTEROL LEVELS IN HUMAN NASH

F. Caballero, R. Bataller, A. Lacy, J.C. Fernandez-Checa, J. Caballeria, C. Garcia-Ruiz

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 65 KB

english, 2008

80

917 METHIONINE DEFICIENCY ACCOUNTS FOR THE LIVER DAMAGE OBSERVED IN A NUTRITIONAL MODEL OF NONALCOHOLIC STEATOHEPATITIS

F. Caballero, A. Fernandez, J.C. Fernandez-Checa, C. Garcia-Ruiz

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

81

76 ENHANCED SUSCEPTIBILITY TO LPS-INDUCED LIVER DAMAGE IN TG-SREBP-2 MICE

A. Fernandez, F. Caballero, C. Garcia-Ruiz, J.c. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

82

138 CRITICAL ROLE OF CHOLESTEROL IN THE SENSITIZATION OF STEATOTIC LIVER TO ISCHEMIA/REPERFUSION INJURY

L. Llacuna, A. Morales, A. Fernandez, J.C. Fernandez-Checa, C. Garcia-Ruiz

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

83

298 ROLE OF TNF RECEPTORS (TNFR1 AND TNFR2) IN HEPATIC STELLATE CELL PROLIFERATION

N. Tarrats, A. Moles, J.C. Fernandez-Checa, M. Marí

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

84

727 THE MITOCHONDRIAL GSH LEVEL IS RESPONSIBLE FOR THE EFFICIENCY AND THE PROTECTIVE EFFECT OF SUPEROXIDE ELIMINATION

C. von Montfort, N. Matias, C. Garcia-Ruiz, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 65 KB

english, 2009

85

95 CAVEOLIN-1 REGULATES MITOCHONRIAL CHOLESTEROL AND HEPATOCELLULAR SUSCEPTIBILITY TO TNF/FAS

M. Mari, M. Bosch, A. Fernandez, A. Kassan, A. Colell, C. Enrich, C. Garcia-Ruiz, A. Pol, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 167 KB

english, 2010

86

804 THE OXIDATIVE ALCOHOL METABOLISM INDUCES THE MITOCHONDRIAL CHOLESTEROL TRANSPORTING POLYPEPTIDE STAR

C. Von Monfort, N. Matias, J. Caballeria, C. Garcia-Ruiz, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

87

960 CHOLESTEROL REGULATES MITOCHONDRIAL RAFT-LIKE DOMAINS DURING TNF/FAS-MEDIATED HEPATOCELLULAR APOPTOSIS

N. Matias, A. Fernandez, V. Manganelli, A. Colell, A. Tinari, W. Malorni, C. Garcia-Ruiz, M. Sorice, J.C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

88

965 ACID SPHINGOMYELINASE CONTROLS HEPATIC STELLATE CELL ACTIVATION AND IN VIVO LIVER FIBROSIS

A. Moles, N. Tarrats, A. Morales, M. Dominguez, R. Bataller, J. Caballeria, C. Garcia-Ruiz, J.C. Fernandez-Checa, M. Mari

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

89

136 OVEREXPRESSION OF 2-OXOGLUTARATE CARRIER IN HEPATOCELLULAR CARCINOMA OVERCOMES CHOLESTEROL-MEDIATED MITOCHONDRIAL GSH DEPLETION TO EVADE CELL DEATH AND PROMOTE IN VIVO TUMOR GROWTH

N. Matias, J. Montero, M. Stefanovic, A. Morales, J. Prieto, C. Garcia-Ruiz, A. Colell, J. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

90

310 SORAFENIB INDUCTION OF SPHINGOLIPIDIC METABOLISM REVEALS CERAMIDASE TARGETING AS A POTENTIAL STRATEGY IN HCC TREATMENT

M. Stefanovic, C. Bárcena, C. García-Ruiz, J.C. Fernández-Checa, A. Morales

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

91

401 CATHEPSIN B OVEREXPRESSION DUE TO ACID SPHINGOMYELINASE ABLATION PROMOTES LIVER FIBROSIS IN NIEMANN PICK DISEASE

N. Tarrats, A. Moles, J.C. Fernandez-Checa, M. Mari

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

92

Reactive Oxygen Species Mediate Liver Injury Through Parenchymal Nuclear Factor-κB Inactivation in Prolonged Ischemia/Reperfusion

Laura Llacuna, Montserrat Marí, Josep M. Lluis, Carmen García-Ruiz, José C. Fernández-Checa, Albert Morales

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

93

Acidic Sphingomyelinase Controls Hepatic Stellate Cell Activation and in Vivo Liver Fibrogenesis

Anna Moles, Núria Tarrats, Albert Morales, Marlene Domínguez, Ramón Bataller, Juan Caballería, Carmen García-Ruiz, José C. Fernández-Checa, Montserrat Marí

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

94

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Anna Colell, Carmen García-Ruiz, Merce Miranda, Esther Ardite, Montse Marí, Albert Morales, Fernando Corrales, Neil Kaplowitz, José C. Fernández-Checa

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 1.29 MB

english, 1998

95

Hepatocellular oxidative stress and initial graft injury in human liver transplantation

Esther Ardite, Clara Ramos, Antoni Rimola, Luis Grande, José Carlos Fernández-Checa

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 875 KB

english, 1999

96

Replenishment of Glutathione Levels Improves Mucosal Function in Experimental Acute Colitis

Ardite, Esther, Sans, Miguel, Panés, Juliá, Romero, Francisco J, Piqué, Josep M, Fernández-Checa, José C

Journal:

Laboratory Investigation

Year:

2000

Language:

english

File:

PDF, 272 KB

english, 2000

97

Evidence that interference with binding to hepatic cytosol binders can inhibit bile acid excretion in rats

H Takikawa, Y Sugiyama, JC Fernandez-Checa, J Kuhlenkamp, M Ookhtens, N Kaplowitz

Journal:

Year:

1996

Language:

english

File:

PDF, 275 KB

english, 1996

98

Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: Effect of membrane physical properties and S-adenosyl-L-methionine

A Colell, C Garcia-Ruiz, A Morales, A Ballesta, M Ookhtens, J Rodes, N Kaplowitz, JC Fernandez-Checa

Journal:

Year:

1997

Language:

english

File:

PDF, 397 KB

english, 1997

99

A hidden face of hope for the liver

Jose C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 60 KB

english, 2004

100

PGE1 reduced caspase-3 and -6 activation induced by D-galactosamine in primary culture of rat hepatocytes, role of oxidative stress

E. Siendones, J. Muntané, A. Quintero, J.L. Montero, J.C. Fernández-Checa, M. De la Mata, G. Miño

Journal:

Journal of Hepatology

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000