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51

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

Anna Colell, Carmen Garcı́a-Ruiz, Montserrat Mari, José C Fernández-Checa

Journal:

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

52

Transcriptional regulation of the heavy subunit chain of γ-glutamylcysteine synthetase by ionizing radiation

Albert Morales, Merce Miranda, Alberto Sanchez-Reyes, Anna Colell, Albert Biete, José C Fernández-Checa

Journal:

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

53

Reactive Oxygen Species Mediate Liver Injury Through Parenchymal Nuclear Factor-κB Inactivation in Prolonged Ischemia/Reperfusion

Laura Llacuna, Montserrat Marí, Josep M. Lluis, Carmen García-Ruiz, José C. Fernández-Checa, Albert Morales

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

54

Acidic Sphingomyelinase Controls Hepatic Stellate Cell Activation and in Vivo Liver Fibrogenesis

Anna Moles, Núria Tarrats, Albert Morales, Marlene Domínguez, Ramón Bataller, Juan Caballería, Carmen García-Ruiz, José C. Fernández-Checa, Montserrat Marí

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

55

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Anna Colell, Carmen García-Ruiz, Merce Miranda, Esther Ardite, Montse Marí, Albert Morales, Fernando Corrales, Neil Kaplowitz, José C. Fernández-Checa

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 1.29 MB

english, 1998

56

Hepatocellular oxidative stress and initial graft injury in human liver transplantation

Esther Ardite, Clara Ramos, Antoni Rimola, Luis Grande, José Carlos Fernández-Checa

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 875 KB

english, 1999

57

Replenishment of Glutathione Levels Improves Mucosal Function in Experimental Acute Colitis

Ardite, Esther, Sans, Miguel, Panés, Juliá, Romero, Francisco J, Piqué, Josep M, Fernández-Checa, José C

Journal:

Laboratory Investigation

Year:

2000

Language:

english

File:

PDF, 272 KB

english, 2000

58

A hidden face of hope for the liver

Jose C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 60 KB

english, 2004

59

117 S-adenosylmethionine protects mice against acute liver failure

Montserrat Marr, Albert Morales, Carmen García-Ruiz, José Carlos Fernández-Checa

Journal:

Year:

2003

Language:

english

File:

PDF, 303 KB

english, 2003

60

870 Mitochondrial glutathione unfolds the apoptotic potential of tumor necrosis factor-alpha (TNF)

Montserrat Marí, Anna Colell, Carmen García-Ruiz, José Carlos Fernández-Checa

Journal:

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

61

Redox Control of Liver Function in Health and Disease

Marí, Montserrat, Colell, Anna, Morales, Albert, von Montfort, Claudia, Garcia-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

62

Role of Mitochondria in Alcoholic Liver Disease

García-Ruiz, Carmen, Kaplowitz, Neil, Fernandez-Checa, José C.

Journal:

Current Pathobiology Reports

Year:

2013

Language:

english

File:

PDF, 260 KB

english, 2013

63

Endoplasmic Reticulum Stress Mediates Amyloid β Neurotoxicity via Mitochondrial Cholesterol Trafficking

Barbero-Camps, Elisabet, Fernández, Anna, Baulies, Anna, Martinez, Laura, Fernández-Checa, Jose C., Colell, Anna

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 2.71 MB

english, 2014

64

P3-371

Colell, Anna, Fernandez, Anna, Fernandez-Checa, Jose C.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

65

P4-184: Increased mitochondrial cholesterol enhances glial activation and neuronal oxidative stress induced by intracerebroventricular infusion of human beta-amyloid

Colell, Anna, Fernández, Anna, García, Alberto, Fernández-Checa, Jose C.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

66

APP/PS1 transgenic mice overexpressing SREBP2 as a new model to study the pathogenic role of cholesterol in Alzheimer's disease (AD)

Barbero, Elisabet, Fernández, Anna, Fernández-Checa, José, Colell, Anna

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

67

SREBP-2-mediated cholesterol accumulation regulates beta-amyloid–induced autophagy in APP/PS1/SREBP-2 mice

Barbero-Camps, Elisabeth, Fernandez-Checa, Jose, Colell, Anna

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 480 KB

english, 2013

68

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress

Marí, Montserrat, Morales, Albert, Colell, Anna, García-Ruiz, Carmen, Fernández-Checa, Jose C.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

69

Expression Cloning of the cDNA for a Polypeptide Associated with Rat Hepatic Sinusoidal Reduced Glutathione Transport: Characteristics and Comparison with the Canalicular Transporter

Jian-Ri Yi, Shilun Lu, Jose Fernandez-Checa and Neil Kaplowitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 977 KB

english, 1995

70

Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: Impact on mitochondrial s-adenosyl-l-methionine and GSH.

Caballero, Francisco, Fernandez, Anna, Matias, Nuria, Martinez, Laura, Fucho, Raquel, Elena, Montserrat, Caballeria, Joan, Morales, Albert, Fernandez-Checa, Jose C., Garcia-Ruiz, Carmen

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 2.33 MB

english, 2010

71

Glycosphingolipids and cell death: one aim, many ways

Garcia-Ruiz, Carmen, Morales, Albert, Fernández-Checa, José C.

Journal:

Year:

2015

Language:

english

File:

PDF, 521 KB

english, 2015

72

Augmenter of Liver Regeneration Links Mitochondrial Function to Steatohepatitis and Hepatocellular Carcinoma

Maehara, Yoshihiko, Fernandez-Checa, Jose C.

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 588 KB

english, 2015

73

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity

Win, Sanda, Than, Tin Aung, Le, Bao Han Allison, García-Ruiz, Carmen, Fernandez-Checa, Jose C., Kaplowitz, Neil

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 5.87 MB

english, 2015

74

Pharmacological Modulation of Sphingolipids and Role in Disease and Cancer Cell Biology

Morales, Albert, Fernandez-Checa, Jose

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

75

Acid sphingomyelinase-ceramide system in steatohepatitis: A novel target regulating multiple pathways

Garcia-Ruiz, Carmen, Mato, Jose M., Vance, Dennis, Kaplowitz, Neil, Fernández-Checa, José C.

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

76

Plasma Membrane and Mitochondrial Transport of Hepatic Reduced Glutathione

Fernández-Checa, José, Yl, Jian-R, Ruiz, Carmen, Ookhtens, Murad, Kaplowitz, Neil

Journal:

Seminars in Liver Disease

Year:

1996

Language:

english

File:

PDF, 1.21 MB

english, 1996

77

To binge or not to binge: Binge drinking disrupts glucose homeostasis by impairing hypothalamic but not liver insulin signaling

Garcia-Ruiz, Carmen, Fernandez-Checa, José C.

Journal:

Year:

2013

Language:

english

File:

PDF, 522 KB

english, 2013

78

Liver and lens glutathione and cysteine regulation in galactose-fed guinea pigs

Kannan, Ram, Fernández-Checa, José C., García-Ruiz, Carmen, Mackic, Jasmina B., Zlokovic, Berislav V.

Journal:

Current Eye Research

Year:

1997

Language:

english

File:

PDF, 280 KB

english, 1997

79

Metabolic Therapy: Lessons from Liver Diseases

Garcia-Ruiz, Carmen, Mari, Montserrat, Colell, Anna, Morales, Albert, C. Fernandez-Checa, Jose

Journal:

Current Pharmaceutical Design

Year:

2011

Language:

english

File:

PDF, 448 KB

english, 2011

80

Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells

Ordoñez, Raquel, Fernández, Anna, Prieto-Domínguez, Néstor, Martínez, Laura, García-Ruiz, Carmen, Fernández-Checa, José C., Mauriz, José L., González-Gallego, Javier

Journal:

Journal of Pineal Research

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

81

Mitochondria, cholesterol and cancer cell metabolism

Ribas, Vicent, García-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Clinical and Translational Medicine

Year:

2016

Language:

english

File:

PDF, 2.12 MB

english, 2016

82

Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy

Prieto-Domínguez, Néstor, Ordóñez, Raquel, Fernández, Anna, Méndez-Blanco, Carolina, Baulies, Anna, Garcia-Ruiz, Carmen, Fernández-Checa, José C., Mauriz, José L., González-Gallego, Javier

Journal:

Journal of Pineal Research

Year:

2016

Language:

english

File:

PDF, 574 KB

english, 2016

83

Angiogenin Secretion From Hepatoma Cells Activates Hepatic Stellate Cells To Amplify A Self-Sustained Cycle Promoting Liver Cancer

Bárcena, Cristina, Stefanovic, Milica, Tutusaus, Anna, Martinez-Nieto, Guillermo A., Martinez, Laura, García-Ruiz, Carmen, de Mingo, Alvaro, Caballeria, Juan, Fernandez-Checa, José C., Marí, Montserra

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

84

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation

de Mingo, Álvaro, de Gregorio, Estefanía, Moles, Anna, Tarrats, Núria, Tutusaus, Anna, Colell, Anna, Fernandez-Checa, Jose C, Morales, Albert, Marí, Montserrat

Journal:

Cell Death and Disease

Year:

2016

Language:

english

File:

PDF, 2.68 MB

english, 2016

85

Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy

Baulies, Anna, Ribas, Vicent, Núñez, Susana, Torres, Sandra, Alarcón-Vila, Cristina, Martínez, Laura, Suda, Jo, Ybanez, Maria D., Kaplowitz, Neil, García-Ruiz, Carmen, Fernández-Checa, Jose C.

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.89 MB

english, 2015

86

MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

Balboa, Elisa, Castro, Juan, Pinochet, María-José, Cancino, Gonzalo I., Matías, Nuria, José Sáez, Pablo, Martínez, Alexis, Álvarez, Alejandra R., Garcia-Ruiz, Carmen, Fernandez-Checa, José C., Zanlung

Journal:

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

87

PROFILE OF INTRACELLULAR CHOLESTEROL TRAFFICKING IN POSTMORTEM BRAINS OF DOWN SYNDROME AND ALZHEIMER DISEASE

Arenas Rios, Fabian O., Diaz-Marugan, Laura, Rodriguez-Peiris, Maria, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose Carlos

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 164 KB

english, 2017

88

Zinc mitigates renal ischemia-reperfusion injury in rats by modulating oxidative stress, endoplasmic reticulum stress, and autophagy

Hadj Abdallah, Najet, Baulies, Anna, Bouhlel, Ahlem, Bejaoui, Mohamed, Zaouali, Mohamed A., Ben Mimouna, Safa, Messaoudi, Imed, Fernandez-Checa, José C., García Ruiz, Carmen, Ben Abdennebi, Hassen

Journal:

Journal of Cellular Physiology

Year:

2018

Language:

english

File:

PDF, 2.29 MB

english, 2018

89

The effect of zinc acexamate on oxidative stress, inflammation and mitochondria induced apoptosis in rat model of renal warm ischemia

Hadj Abdallah, Najet, Baulies, Anna, Bouhlel, Ahlem, Bejaoui, Mohamed, Zaouali, Mohamed Amine, Ben Mimouna, Safa, Messaoudi, Imed, Fernandez-Checa, José Carlos, García Ruiz, Carmen, Ben Abdennebi, Has

Journal:

Biomedicine & Pharmacotherapy

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

90

GD3 Synthase Overexpression Sensitizes Hepatocarcinoma Cells to Hypoxia and Reduces Tumor Growth by Suppressing the cSrc/NF-κB Survival Pathway

Lluis, Josep M., Llacuna, Laura, von Montfort, Claudia, Bárcena, Cristina, Enrich, Carlos, Morales, Albert, Fernandez-Checa, José C., Jin, Dong-Yan

Journal:

Year:

2009

Language:

english

File:

PDF, 541 KB

english, 2009

91

Tauroursodeoxycholic acid protects against valproic acid-induced sensitization to acetaminophen hepatotoxicity

Torres, S., Baulies, A., Insausti-Urkia, N., Alarcón-Vila, C., Fucho, R., Solsona, E., Núñez, S., Garcia-Ruiz, M.C., Fernandez-Checa, José

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 65 KB

english, 2018

92

Cholesterol-mediated expression of ganglioside GD3 acetylation contributes to liver fibrogenesis

Vallejo, C., Ribas, V., Robles, D., Torres, S., Ramos, J., Caballeria, J., Elena, M., Fernandez-Checa, José, Garcia-Ruiz, M.C.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 67 KB

english, 2018

93

Intracellular Cholesterol Trafficking and Impact in Neurodegeneration

Arenas, Fabian, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.

Journal:

Frontiers in Molecular Neuroscience

Year:

2017

Language:

english

File:

PDF, 4.26 MB

english, 2017

94

Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity

Moles, Anna, Torres, Sandra, Baulies, Anna, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

95

Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease

Torres, Sandra, Balboa, Elisa, Zanlungo, Silvana, Enrich, Carlos, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.

Journal:

Frontiers in Physiology

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

96

Mitochondrial Oxidative Stress and Antioxidants Balance in Fatty Liver Disease

García-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Hepatology Communications

Year:

2018

Language:

english

File:

PDF, 426 KB

english, 2018

97

Consumption of decaffeinated coffee protects against the development of early non-alcoholic steatohepatitis: Role of intestinal barrier function

Brandt, Annette, Nier, Anika, Jin, Cheng Jun, Baumann, Anja, Jung, Finn, Ribas, Vicent, García-Ruiz, Carmen, Fernández-Checa, Jose C., Bergheim, Ina

Journal:

Year:

2019

Language:

english

File:

PDF, 4.70 MB

english, 2019

98

Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes

Solsona-Vilarrasa, Estel, Fucho, Raquel, Torres, Sandra, Nuñez, Susana, Nuño, Natalia, Enrich, Carlos, García-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.90 MB

english, 2019

99

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma

Tutusaus, Anna, Stefanovic, Milica, Boix, Loreto, Cucarull, Blanca, Zamora, Aynara, Blasco, Laura, de Frutos, Pablo García, Reig, Maria, Fernandez-Checa, Jose C., Marí, Montserrat, Colell, Anna, Bruix

Journal:

Year:

2018

Language:

english

File:

PDF, 10.20 MB

english, 2018

100

THU-264-Transmission electron microscopy reveals dramatic hepatic zonal changes upon chronic alcohol feeding

Fucho, Raquel, Solsona-Vilarrasa, Estel, Enrich, Carlos, Garcia-Ruiz, M. Carmen, Fernandez-Checa, José

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 335 KB

english, 2019