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51

Expression Cloning of the cDNA for a Polypeptide Associated with Rat Hepatic Sinusoidal Reduced Glutathione Transport: Characteristics and Comparison with the Canalicular Transporter

Jian-Ri Yi, Shilun Lu, Jose Fernandez-Checa and Neil Kaplowitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 977 KB

english, 1995

52

Acid sphingomyelinase-ceramide system in steatohepatitis: A novel target regulating multiple pathways

Garcia-Ruiz, Carmen, Mato, Jose M., Vance, Dennis, Kaplowitz, Neil, Fernández-Checa, José C.

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

53

Angiogenin Secretion From Hepatoma Cells Activates Hepatic Stellate Cells To Amplify A Self-Sustained Cycle Promoting Liver Cancer

Bárcena, Cristina, Stefanovic, Milica, Tutusaus, Anna, Martinez-Nieto, Guillermo A., Martinez, Laura, García-Ruiz, Carmen, de Mingo, Alvaro, Caballeria, Juan, Fernandez-Checa, José C., Marí, Montserra

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

54

Zinc mitigates renal ischemia-reperfusion injury in rats by modulating oxidative stress, endoplasmic reticulum stress, and autophagy

Hadj Abdallah, Najet, Baulies, Anna, Bouhlel, Ahlem, Bejaoui, Mohamed, Zaouali, Mohamed A., Ben Mimouna, Safa, Messaoudi, Imed, Fernandez-Checa, José C., García Ruiz, Carmen, Ben Abdennebi, Hassen

Journal:

Journal of Cellular Physiology

Year:

2018

Language:

english

File:

PDF, 2.29 MB

english, 2018

55

Ceramide, Tumor Necrosis Factor and Alcohol-Induced Liver Disease

José C. Fernandez-Checa, Anna Colell, Montserrat Mari, Carmen García-Ruiz

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2005

Language:

english

File:

PDF, 570 KB

english, 2005

56

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

Joan Montero, Montserrat Mari, Anna Colell, Albert Morales, Gorka Basañez, Carmen Garcia-Ruiz, Jose C. Fernández-Checa

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2010

Language:

english

File:

PDF, 822 KB

english, 2010

57

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

Francisco Caballero, Anna Fernández, Antonio M. De Lacy, Jose C. Fernández-Checa, Juan Caballería, Carmen García-Ruiz

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 691 KB

english, 2009

58

Transcriptional regulation of the heavy subunit chain of γ-glutamylcysteine synthetase by ionizing radiation

Albert Morales, Merce Miranda, Alberto Sanchez-Reyes, Anna Colell, Albert Biete, José C Fernández-Checa

Journal:

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

59

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Anna Colell, Carmen García-Ruiz, Merce Miranda, Esther Ardite, Montse Marí, Albert Morales, Fernando Corrales, Neil Kaplowitz, José C. Fernández-Checa

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 1.29 MB

english, 1998

60

Plasma Membrane and Mitochondrial Transport of Hepatic Reduced Glutathione

Fernández-Checa, José, Yl, Jian-R, Ruiz, Carmen, Ookhtens, Murad, Kaplowitz, Neil

Journal:

Seminars in Liver Disease

Year:

1996

Language:

english

File:

PDF, 1.21 MB

english, 1996

61

Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes

Solsona-Vilarrasa, Estel, Fucho, Raquel, Torres, Sandra, Nuñez, Susana, Nuño, Natalia, Enrich, Carlos, García-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.90 MB

english, 2019

62

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity

Win, Sanda, Than, Tin Aung, Le, Bao Han Allison, García-Ruiz, Carmen, Fernandez-Checa, Jose C., Kaplowitz, Neil

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 5.87 MB

english, 2015

63

Consumption of decaffeinated coffee protects against the development of early non-alcoholic steatohepatitis: Role of intestinal barrier function

Brandt, Annette, Nier, Anika, Jin, Cheng Jun, Baumann, Anja, Jung, Finn, Ribas, Vicent, García-Ruiz, Carmen, Fernández-Checa, Jose C., Bergheim, Ina

Journal:

Year:

2019

Language:

english

File:

PDF, 4.70 MB

english, 2019

64

A hidden face of hope for the liver

Jose C. Fernandez-Checa

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 60 KB

english, 2004

65

THU-264-Transmission electron microscopy reveals dramatic hepatic zonal changes upon chronic alcohol feeding

Fucho, Raquel, Solsona-Vilarrasa, Estel, Enrich, Carlos, Garcia-Ruiz, M. Carmen, Fernandez-Checa, José

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 335 KB

english, 2019

66

Cholesterol Induces Nrf-2- and HIF-1 Î± -Dependent Hepatocyte Proliferation and Liver Regeneration to Ameliorate Bile Acid Toxicity in Mouse Models of NASH and Fibrosis

Kaminsky-Kolesnikov, Yula, Rauchbach, Einat, Abu-Halaka, Diana, Hahn, Michal, GarcÃa-Ruiz, Carmen, Fernandez-Checa, Jose C., Madar, Zecharia, Tirosh, Oren

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2020

File:

PDF, 3.80 MB

2020

67

Growth arrest–specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury

Laura Llacuna, Cristina Bárcena, Lola Bellido-Martín, Laura Fernández, Milica Stefanovic, Montserrat Marí, Carmen García-Ruiz, José C. Fernández-Checa, Pablo García de Frutos, Albert Morales

Journal:

Year:

2010

Language:

english

File:

PDF, 500 KB

english, 2010

68

Conference article: Alcoholic liver injury and apoptosis—synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001

Manuela G Neuman, Gady G Katz, Izabella M Malkiewicz, Philippe Mathurin, Hidekazu Tsukamoto, Masayuki Adachi, Hiromasa Ishii, Anna Colell, Carmen Garcı́a-Ruiz, José C Fernández-Checa, Carol A Casey

Journal:

Year:

2002

Language:

english

File:

PDF, 121 KB

english, 2002

69

Replenishment of Glutathione Levels Improves Mucosal Function in Experimental Acute Colitis

Ardite, Esther, Sans, Miguel, Panés, Juliá, Romero, Francisco J, Piqué, Josep M, Fernández-Checa, José C

Journal:

Laboratory Investigation

Year:

2000

Language:

english

File:

PDF, 272 KB

english, 2000

70

Augmenter of Liver Regeneration Links Mitochondrial Function to Steatohepatitis and Hepatocellular Carcinoma

Maehara, Yoshihiko, Fernandez-Checa, Jose C.

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 588 KB

english, 2015

71

Mitochondria, cholesterol and cancer cell metabolism

Ribas, Vicent, García-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Clinical and Translational Medicine

Year:

2016

Language:

english

File:

PDF, 2.12 MB

english, 2016

72

THU-264-Transmission electron microscopy reveals dramatic hepatic zonal changes upon chronic alcohol feeding

Fucho, Raquel, Solsona-Vilarrasa, Estel, Enrich, Carlos, Garcia-Ruiz, M. Carmen, Fernandez-Checa, José

Journal:

Journal of Hepatology

Year:

2019

File:

PDF, 335 KB

2019

73

Sphingolipids and cell death

Albert Morales, Hyunmi Lee, Felix M. Goñi, Richard Kolesnick, José C. Fernandez-Checa

Journal:

Year:

2007

Language:

english

File:

PDF, 500 KB

english, 2007

74

Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy

Baulies, Anna, Ribas, Vicent, Núñez, Susana, Torres, Sandra, Alarcón-Vila, Cristina, Martínez, Laura, Suda, Jo, Ybanez, Maria D., Kaplowitz, Neil, García-Ruiz, Carmen, Fernández-Checa, Jose C.

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.89 MB

english, 2015

75

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma

Tutusaus, Anna, Stefanovic, Milica, Boix, Loreto, Cucarull, Blanca, Zamora, Aynara, Blasco, Laura, de Frutos, Pablo García, Reig, Maria, Fernandez-Checa, Jose C., Marí, Montserrat, Colell, Anna, Bruix

Journal:

Year:

2018

Language:

english

File:

PDF, 10.20 MB

english, 2018

76

Cholesterol regulates mitochondrial raft-like domains during TNF/Fas-mediated hepatocellular apoptosis

Nuria Matías, Anna Fernández, Valeria Manganelli, Anna Colell, Antonella Tinari, Walter Malorni, Carmen Garcia-Ruiz, Mauricio Sorice, José C. Fernández-Checa

Journal:

Chemistry and Physics of Lipids

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

77

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

Anna Colell, Carmen Garcı́a-Ruiz, Montserrat Mari, José C Fernández-Checa

Journal:

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

78

Human Placenta Sphingomyelinase, an Exogenous Acidic pH-Optimum Sphingomyelinase, Induces Oxidative Stress, Glutathione Depletion, and Apoptosis in Rat Hepatocytes

Carmen Garcı́a-Ruiz, Montse Marı́, Albert Morales, Anna Colell, Esther Ardite, José C. Fernández-Checa

Journal:

Year:

2000

Language:

english

File:

PDF, 419 KB

english, 2000

79

870 Mitochondrial glutathione unfolds the apoptotic potential of tumor necrosis factor-alpha (TNF)

Montserrat Marí, Anna Colell, Carmen García-Ruiz, José Carlos Fernández-Checa

Journal:

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

80

117 S-adenosylmethionine protects mice against acute liver failure

Montserrat Marr, Albert Morales, Carmen García-Ruiz, José Carlos Fernández-Checa

Journal:

Year:

2003

Language:

english

File:

PDF, 303 KB

english, 2003

81

Editorial: Autophagy and Related Transcription Factors in Liver and Gut Diseases

Eid, Nabil, Menon, Manoj B., Thomes, Paul, Zeng, Tao, Raimundo, Nuno, Fernandez-Checa, Jose C., Wang, Lin, Ito, Yuko, Otsuki, Yoshinori, Adeghate, Ernest

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 242 KB

2020

82

Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor–induced cell death by replenishing mitochondrial glutathione

Anna Colell, Olga Coll, Carmen Garcı́a-Ruiz, Raquel Parı́s, Claudio Tiribelli, Neil Kaplowitz, José C. Fernández-Checa

Journal:

Year:

2001

Language:

english

File:

PDF, 301 KB

english, 2001

83

Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-α-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation: Possible role of ganglioside GD3

Anna Colell, Albert Morales, José C Fernández-Checa, Carmen Garcı́a-Ruiz

Journal:

Year:

2002

Language:

english

File:

PDF, 360 KB

english, 2002

84

P3-371

Colell, Anna, Fernandez, Anna, Fernandez-Checa, Jose C.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

85

Metabolic Therapy: Lessons from Liver Diseases

Garcia-Ruiz, Carmen, Mari, Montserrat, Colell, Anna, Morales, Albert, C. Fernandez-Checa, Jose

Journal:

Current Pharmaceutical Design

Year:

2011

Language:

english

File:

PDF, 448 KB

english, 2011

86

PROFILE OF INTRACELLULAR CHOLESTEROL TRAFFICKING IN POSTMORTEM BRAINS OF DOWN SYNDROME AND ALZHEIMER DISEASE

Arenas Rios, Fabian O., Diaz-Marugan, Laura, Rodriguez-Peiris, Maria, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose Carlos

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 164 KB

english, 2017

87

Mitochondrial Cholesterol in Alzheimer's Disease and Niemann–Pick Type C Disease

Torres, Sandra, García-Ruiz, Carmen M., Fernandez-Checa, Jose C.

Journal:

Frontiers in Neurology

Year:

2019

File:

PDF, 540 KB

2019

88

Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia–reperfusion injury

Laura Llacuna, Anna Fernández, Claudia Von Montfort, Núria Matías, Laura Martínez, Francisco Caballero, Antoni Rimola, Montserrat Elena, Albert Morales, José C. Fernández-Checa, Carmen García-Ruiz

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 2.20 MB

english, 2011

89

Mitochondrial Oxidative Stress and Antioxidants Balance in Fatty Liver Disease

García-Ruiz, Carmen, Fernández-Checa, José C.

Journal:

Hepatology Communications

Year:

2018

Language:

english

File:

PDF, 426 KB

english, 2018

90

Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury

Laura Llacuna, Montserrat Marí, Carmen Garcia-Ruiz, José C. Fernandez-Checa, Albert Morales

Journal:

Year:

2006

Language:

english

File:

PDF, 1.32 MB

english, 2006

91

Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

Anna Moles, Núria Tarrats, José C. Fernández-Checa, Montserrat Marí

Journal:

Year:

2009

Language:

english

File:

PDF, 4.10 MB

english, 2009

92

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

Montserrat Marí, Francisco Caballero, Anna Colell, Albert Morales, Juan Caballeria, Anna Fernandez, Carlos Enrich, José C. Fernandez-Checa, Carmen García-Ruiz

Journal:

Cell Metabolism

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

93

Tauroursodeoxycholic acid protects against valproic acid-induced sensitization to acetaminophen hepatotoxicity

Torres, S., Baulies, A., Insausti-Urkia, N., Alarcón-Vila, C., Fucho, R., Solsona, E., Núñez, S., Garcia-Ruiz, M.C., Fernandez-Checa, José

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 65 KB

english, 2018

94

A Simple Technique to Determine Glutathione (GSH) Levels and Synthesis in Ocular Tissues as GSH-bimane Adduct: Application to Normal and Galactosemic Guinea-pigs

Ram Kannan, Diana Tang, Jasmina B. Mackic, Berislav V. Zlokovic, Jose C. Fernandez-Checa

Journal:

Experimental Eye Research

Year:

1993

File:

PDF, 358 KB

1993

95

Redox regulation and signaling lipids in mitochondrial apoptosis

José C. Fernández-Checa

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 169 KB

english, 2003

96

Reactive Oxygen Species Mediate Liver Injury Through Parenchymal Nuclear Factor-κB Inactivation in Prolonged Ischemia/Reperfusion

Laura Llacuna, Montserrat Marí, Josep M. Lluis, Carmen García-Ruiz, José C. Fernández-Checa, Albert Morales

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

97

Glycosphingolipids and cell death: one aim, many ways

Garcia-Ruiz, Carmen, Morales, Albert, Fernández-Checa, José C.

Journal:

Year:

2015

Language:

english

File:

PDF, 521 KB

english, 2015

98

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation

de Mingo, Álvaro, de Gregorio, Estefanía, Moles, Anna, Tarrats, Núria, Tutusaus, Anna, Colell, Anna, Fernandez-Checa, Jose C, Morales, Albert, Marí, Montserrat

Journal:

Cell Death and Disease

Year:

2016

Language:

english

File:

PDF, 2.68 MB

english, 2016

99

Intracellular Cholesterol Trafficking and Impact in Neurodegeneration

Arenas, Fabian, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.

Journal:

Frontiers in Molecular Neuroscience

Year:

2017

Language:

english

File:

PDF, 4.26 MB

english, 2017

100

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-κB activation and apoptosis in human colon HT-29 cells

Anna Colell, Olga Coll, Montse Marı́, José C Fernández-Checa, Carmen Garcı́a-Ruiz

Journal:

Year:

2002

Language:

english

File:

PDF, 322 KB

english, 2002

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