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1

Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest

Vincentz, Joshua W., Firulli, Beth A., Lin, Andrea, Spicer, Douglas B., Howard, Marthe J., Firulli, Anthony B., Bronner, Marianne E.

Journal:

Year:

2013

Language:

english

File:

PDF, 22.21 MB

english, 2013

2

Nkx2.5 regulates endothelin converting enzyme-1 during pharyngeal arch patterning

Iklé, Jennifer M., Tavares, Andre L. P., King, Marisol, Ding, Hailei, Colombo, Sophie, Firulli, Beth A., Firulli, Anthony B., Targoff, Kimara L., Yelon, Deborah, Clouthier, David E.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.27 MB

english, 2017

3

Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis

Firulli, Beth A., Milliar, Hannah, Toolan, Kevin P., Harkin, Jade, Fuchs, Robyn K., Robling, Alex G., Firulli, Anthony B.

Journal:

Development (The Company of Biologists)

Year:

2017

Language:

english

File:

PDF, 22.50 MB

english, 2017

4

Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification

Miao, Lianjie, Li, Jingjing, Li, Jun, Tian, Xueying, Lu, Yangyang, Hu, Saiyang, Shieh, David, Kanai, Ryan, Zhou, Bo-yang, Zhou, Bin, Liu, Jiandong, Firulli, Anthony B., Martin, James F., Singer, Harol

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 10.97 MB

english, 2018

5

Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency

Gan, Peiheng, Patterson, Michaela, Velasquez, Alexa, Wang, Kristy, Tian, Di, Windle, Jolene J., Tao, Ge, Judge, Daniel P., Makita, Takako, Park, Thomas J., Sucov, Henry M., Firulli, Anthony B.

Journal:

Year:

2019

Language:

english

File:

PDF, 4.46 MB

english, 2019

6

Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes

Vincentz, Joshua W., Clouthier, David E., Firulli, Anthony B.

Journal:

Journal of Cardiovascular Development and Disease

Year:

2020

File:

PDF, 12.35 MB

2020

7

Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes

GrÃ¼ndl, Marco, Walz, Susanne, Hauf, Laura, Schwab, Melissa, Werner, Kerstin Marcela, Spahr, Susanne, Schulte, Clemens, Maric, Hans Michael, Ade, Carsten P., Gaubatz, Stefan, Firulli, Anthony B.

Journal:

Year:

2020

File:

PDF, 10.81 MB

2020

8

Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects

Joshua W. Vincentz, Ralston M. Barnes, Anthony B. Firulli

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

9

Combinatorial transcriptional interaction within the cardiac neural crest: A pair of HANDs in heart formation

Anthony B. Firulli, Simon J. Conway

Journal:

Birth Defects Research Part C: Embryo Today: Reviews

Year:

2004

Language:

english

File:

PDF, 381 KB

english, 2004

10

Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development

Joshua W. Vincentz, Ralston M. Barnes, Beth A. Firulli, Simon J. Conway, Anthony B. Firulli

Journal:

Developmental Dynamics

Year:

2008

Language:

english

File:

PDF, 7.12 MB

english, 2008

11

Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability

Beth A. Firulli, David P. McConville, James S. Byers III, Joshua W. Vincentz, Ralston M. Barnes, Anthony B. Firulli

Journal:

Developmental Dynamics

Year:

2010

Language:

english

File:

PDF, 3.85 MB

english, 2010

12

Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives

Ralston M. Barnes, Beth A. Firulli, Simon J. Conway, Joshua W. Vincentz, Anthony B. Firulli

Journal:

Developmental Dynamics

Year:

2010

Language:

english

File:

PDF, 7.82 MB

english, 2010

13

A bHLH Code for Cardiac Morphogenesis

Simon J. Conway, Beth Firulli, Anthony B. Firulli

Journal:

Pediatric Cardiology

Year:

2010

Language:

english

File:

PDF, 439 KB

english, 2010

14

Gene Replacement Strategies to Test the Functional Redundancy of Basic Helix–Loop–Helix Transcription Factor

Anthony B. Firulli, Beth A. Firulli, Jian Wang, Rhonda H. Rogers, Simon J. Conway

Journal:

Pediatric Cardiology

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

15

A comparative molecular analysis of four rat smooth muscle cell lines

Anthony B. Firulli, David Han, Louise Kelly-Roloff, Victor E. Koteliansky, Stephen M. Schwartz, Eric N. Olson, Joseph M. Miano

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1998

Language:

english

File:

PDF, 2.47 MB

english, 1998

16

Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1

Firulli, Anthony B., McFadden, David G., Lin, Qing, Srivastava, Deepak, Olson, Eric N.

Journal:

Nature Genetics

Year:

1998

File:

PDF, 811 KB

1998

17

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

Firulli, Beth A, Krawchuk, Dayana, Centonze, Victoria E, Vargesson, Neil, Virshup, David M, Conway, Simon J, Cserjesi, Peter, Laufer, Ed, Firulli, Anthony B

Journal:

Nature Genetics

Year:

2005

Language:

english

File:

PDF, 636 KB

english, 2005

18

Fluorescence resonance energy transfer (FRET) as a method to calculate the dimerization strength of basic Helix-Loop-Helix (bHLH) proteins

Victoria E. Centonze, Beth A. Firulli, Anthony B. Firulli

Journal:

Biological Procedures Online

Year:

2004

Language:

english

File:

PDF, 191 KB

english, 2004

19

Phosphopeptide mapping of proteins ectopically expressed in tissue culture cell lines

Beth A. Firulli, David M. Virshup, Anthony B. Firulli

Journal:

Biological Procedures Online

Year:

2004

Language:

english

File:

PDF, 334 KB

english, 2004

20

Ontogeny of Cardiac Sympathetic Innervation and Its Implications for Cardiac Disease

Vincentz, Joshua W., Rubart, Michael, Firulli, Anthony B.

Journal:

Pediatric Cardiology

Year:

2012

Language:

english

File:

PDF, 241 KB

english, 2012

21

Functional Screening of Intracardiac Cell Transplants Using Two-Photon Fluorescence Microscopy

Tao, Wen, Soonpaa, Mark H., Field, Loren J., Chen, Peng-Sheng, Firulli, Anthony B., Shou, Weinian, Rubart, Michael

Journal:

Pediatric Cardiology

Year:

2012

Language:

english

File:

PDF, 765 KB

english, 2012

22

Modular regulation of muscle gene transcription: a mechanism for muscle cell diversity

Anthony B. Firulli, Eric N. Olson

Journal:

Trends in Genetics

Year:

1997

Language:

english

File:

PDF, 3.27 MB

english, 1997

23

Evolution of muscle cell diversity through modular enhancers

A.B. Firulli, E.N. Olson

Journal:

Trends in Genetics

Year:

1997

Language:

english

File:

PDF, 166 KB

english, 1997

24

Triplex Forming Ability of a c-myc Promoter Element Predicts Promoter Strength

A.B. Firulli, D.C. Maibenco, A.J. Kinniburgh

Journal:

Archives of Biochemistry and Biophysics

Year:

1994

File:

PDF, 594 KB

1994

25

The Basic-Helix-Loop-Helix Transcription Factor HAND2 Directly Regulates Transcription of the Atrial Naturetic Peptide Gene

Bijoy D. Thattaliyath, Beth A. Firulli, Anthony B. Firulli

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 921 KB

english, 2002

26

Another Hat for Myocardin

Anthony B. Firulli

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 64 KB

english, 2002

27

Twist factor regulation of non-cardiomyocyte cell lineages in the developing heart

Nathan J. VanDusen, Anthony B. Firulli

Journal:

Differentiation

Year:

2012

Language:

english

File:

PDF, 764 KB

english, 2012

28

Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer

Andrew Lindsley, Paige Snider, Hongming Zhou, Rhonda Rogers, Jian Wang, Michael Olaopa, Agnieszka Kruzynska-Frejtag, Shrinagesh V. Koushik, Brenda Lilly, John B.E. Burch, Anthony B. Firulli, Simon J.

Journal:

Developmental Biology

Year:

2007

Language:

english

File:

PDF, 2.76 MB

english, 2007

29

Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons

Tyler J. Hendershot, Hongbin Liu, David E. Clouthier, Iain T. Shepherd, Eva Coppola, Michèle Studer, Anthony B. Firulli, Douglas L. Pittman, Marthe J. Howard

Journal:

Developmental Biology

Year:

2008

Language:

english

File:

PDF, 6.16 MB

english, 2008

30

An absence of Twist1 results in aberrant cardiac neural crest morphogenesis

Joshua W. Vincentz, Ralston M. Barnes, Rhonda Rodgers, Beth A. Firulli, Simon J. Conway, Anthony B. Firulli

Journal:

Developmental Biology

Year:

2008

Language:

english

File:

PDF, 1.98 MB

english, 2008

31

Twist1 is required for cardiac neural crest morphogenesis

Joshua W. Vincentz, Ralston M. Barnes, Rhonda Rogers, Beth A. Firulli, Simon J. Conway, Anthony B. Firulli

Journal:

Developmental Biology

Year:

2008

Language:

english

File:

PDF, 114 KB

english, 2008

32

Twist-family member interactions regulate cardiac neural crest morphogenesis

Joshua W. Vincentz, Ralston M. Barnes, Beth A. Firulli, Simon J. Conway, Anthony B. Firulli

Journal:

Developmental Biology

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

33

Targeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract development

Kristen L. Holler, Tyler J. Hendershot, Sophia E. Troy, Joshua W. Vincentz, Anthony B. Firulli, Marthe J. Howard

Journal:

Developmental Biology

Year:

2010

Language:

english

File:

PDF, 3.81 MB

english, 2010

34

Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects

Sunyong Tang, Paige Snider, Antony B. Firulli, Simon J. Conway

Journal:

Developmental Biology

Year:

2010

Language:

english

File:

PDF, 4.88 MB

english, 2010

35

HAND1 and HAND2 are expressed in the adult-rodent heart and are modulated during cardiac hypertrophy

Bijoy D Thattaliyath, Carolina B Livi, Mark E Steinhelper, Glenn M Toney, Anthony B Firulli

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 195 KB

english, 2002

36

The identification of a tandem H-DNA structure in the c-MYC nuclease sensitive promoter element

Anthony B. Firulli, Douglas C. Maibenco, Alan J. Kinniburgh

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 680 KB

english, 1992

37

HAND2 synergistically enhances transcription of dopamine-β-hydroxylase in the presence of Phox2a

Haiming Xu, Anthony B Firulli, Xiaotong Zhang, Marthe J Howard

Journal:

Developmental Biology

Year:

2003

Language:

english

File:

PDF, 498 KB

english, 2003

38

A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix–loop–helix transcription factors

Anthony B. Firulli

Journal:

Year:

2003

Language:

english

File:

PDF, 2.34 MB

english, 2003

39

PKA, PKC, and the Protein Phosphatase 2A Influence HAND Factor Function: A Mechanism for Tissue-Specific Transcriptional Regulation

Beth A Firulli, Marthe J Howard, Jennifer R McDaid, Leanne McIlreavey, Karen M Dionne, Victoria E Centonze, Peter Cserjesi, David M Virshup, Anthony B Firulli

Journal:

Year:

2003

Language:

english

File:

PDF, 524 KB

english, 2003

40

Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death

VanDusen, Nathan J., Vincentz, Joshua W., Firulli, Beth A., Howard, Marthe J., Rubart, Michael, Firulli, Anthony B.

Journal:

Developmental Biology

Year:

2014

Language:

english

File:

PDF, 12.23 MB

english, 2014

41

Twist 1 controls cell fate decisions within the cardiac neural crest

Vincentz, Joshua W., Firulli, Beth A., Lin, Andrea, Spicer, Douglas B., Howard, Marthe J., Firulli, Anthony B.

Journal:

Autonomic Neuroscience

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

42

DNA triplexes and regulation of the c-myc gene

Kinniburgh, Alan J., Firulli, Anthony B., Kolluri, Rukmini

Journal:

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

43

Another Hat for Myocardin

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 64 KB

english, 2002

44

Ribonucleoprotein and Protein Factors Bind to an H-DNA-Forming c-myc DNA Element: Possible Regulators of the c-myc Gene

Terri L. Davis, Anthony B. Firulli and Alan J. Kinniburgh

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.20 MB

english, 1989

45

Restricted Expression of Homeobox Genes Distinguishes Fetal from Adult Human Smooth Muscle Cells

Joseph M. Miano, Anthony B. Firulli, Eric N. Olson, Paul Hara, Cecilia M. Giachelli and Stephen M. Schwartz

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.29 MB

english, 1996

46

The Transcription Factor Twist1 Limits T Helper 17 and T Follicular Helper Cell Development by Repressing the Gene Encoding the Interleukin-6 Receptor Chain

Pham, D., Walline, C. C., Hollister, K., Dent, A. L., Blum, J. S., Firulli, A. B., Kaplan, M. H.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 2.70 MB

english, 2013

47

Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration

Schindler, Y. L., Garske, K. M., Wang, J., Firulli, B. A., Firulli, A. B., Poss, K. D., Yelon, D.

Journal:

Development (The Company of Biologists)

Year:

2014

Language:

english

File:

PDF, 1.92 MB

english, 2014

48

Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells

Zook, E. C., Krishack, P. A., Zhang, S., Zeleznik-Le, N. J., Firulli, A. B., Witte, P. L., Le, P. T.

Journal:

Year:

2011

Language:

english

File:

PDF, 550 KB

english, 2011

49

Twist1 Regulates Ifng Expression in Th1 Cells by Interfering with Runx3 Function

Pham, D., Vincentz, J. W., Firulli, A. B., Kaplan, M. H.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

50

A Phosphomimetic Mutation in the Sall1 Repression Motif Disrupts Recruitment of the Nucleosome Remodeling and Deacetylase Complex and Repression of Gbx2

Lauberth, Shannon M., Bilyeu, Amy C., Firulli, Beth A., Kroll, Kristen L., Rauchman, Michael

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 957 KB

english, 2007