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1

Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes

Staahl, Brett T, Benekareddy, Madhurima, Coulon-Bainier, Claire, Banfal, Ashwin A, Floor, Stephen N, Sabo, Jennifer K, Urnes, Cole, Munares, Gabriela Acevedo, Ghosh, Anirvan, Doudna, Jennifer A

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

2

Move Over, Genomes: Here Comes Transcriptome Engineering

Thai, Bao, Floor, Stephen N.

Journal:

The CRISPR Journal

Year:

2018

Language:

english

File:

PDF, 312 KB

english, 2018

3

SRP RNA controls a conformational switch regulating the SRP–SRP receptor interaction

Neher, Saskia B, Bradshaw, Niels, Floor, Stephen N, Gross, John D, Walter, Peter

Journal:

Nature Structural and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 861 KB

english, 2008

4

A split active site couples cap recognition by Dcp2 to activation

Floor, Stephen N, Jones, Brittnee N, Hernandez, Gail A, Gross, John D

Journal:

Nature Structural and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.00 MB

english, 2010

5

Ligand-Induced Conformational Heterogeneity of Cytochrome P450 CYP119 Identified by 2D NMR Spectroscopy with the Unnatural Amino Acid 13C-p-Methoxyphenylalanine

Lampe, Jed N., Floor, Stephen N., Gross, John D., Nishida, Clinton R., Jiang, Yongying, Trnka, Michael J., Ortiz de Montellano, Paul R.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 128 KB

english, 2008

6

mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2

Mandar V. Deshmukh, Brittnee N. Jones, Duc-Uy Quang-Dang, Jeremy Flinders, Stephen N. Floor, Candice Kim, Jacek Jemielity, Marcin Kalek, Edward Darzynkiewicz, John D. Gross

Journal:

Year:

2008

Language:

english

File:

PDF, 1.62 MB

english, 2008

7

Mismatch repair protein expression in 1049 endometrial carcinomas, associations with body mass index, and other clinicopathologic variables

Joehlin-Price, Amy S., Perrino, Carmen M., Stephens, Julie, Backes, Floor J., Goodfellow, Paul J., Cohn, David E., Suarez, Adrian A.

Journal:

Gynecologic Oncology

Year:

2014

Language:

english

File:

PDF, 330 KB

english, 2014

8

Engineering Inhibitor Specificity in the Dead-Box Protein Family

Condon, Kendall, Floor, Stephen, Doudna, Jennifer

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

9

Active Site Conformational Dynamics Are Coupled to Catalysis in the mRNA Decapping Enzyme Dcp2

Aglietti, Robin A., Floor, Stephen N., McClendon, Chris L., Jacobson, Matthew P., Gross, John D.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

10

Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome

Floor, Stephen N., Doudna, Jennifer A.

Journal:

Year:

2015

Language:

english

File:

PDF, 384 KB

english, 2015

11

Autoinhibitory Interdomain Interactions and Subfamily-Specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3

Floor, Stephen N., Condon, Kendall J., Sharma, Deepak, Jankowsky, Eckhard, Doudna, Jennifer A.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.74 MB

english, 2015

12

Control of mRNA decapping by Dcp2: An open and shut case?

Floor, Stephen N., Jones, Brittnee N., Gross, John D.

Journal:

Year:

2008

Language:

english

File:

PDF, 399 KB

english, 2008

13

Analog sensitive chemical inhibition of the DEAD-box protein DDX3

Floor, Stephen N., Barkovich, Krister J., Condon, Kendall J., Shokat, Kevan M., Doudna, Jennifer A.

Journal:

Protein Science

Year:

2016

Language:

english

File:

PDF, 3.01 MB

english, 2016

14

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor

Iwasaki, Shintaro, Floor, Stephen N., Ingolia, Nicholas T.

Journal:

Year:

2016

Language:

english

File:

PDF, 12.68 MB

english, 2016

15

Eccentricity Evolution in Simulated Galaxy Clusters

Floor, Stephen N., Melott, Adrian L., Miller, Christopher J., Bryan, Greg L.

Journal:

The Astrophysical Journal

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

16

Simulated Versus Observed Cluster Eccentricity Evolution

Floor, Stephen N., Melott, Adrian L., Motl, Patrick M.

Journal:

The Astrophysical Journal

Year:

2004

Language:

english

File:

PDF, 92 KB

english, 2004

17

The Microcystic, Elongated, and Fragmented (MELF) Pattern of Invasion

Joehlin-Price, Amy S., McHugh, Kelsey E., Stephens, Julie A., Li, Zaibo, Backes, Floor J., Cohn, David E., Cohen, David W., Suarez, Adrian A.

Journal:

American Journal of Surgical Pathology

Year:

2017

Language:

english

File:

PDF, 388 KB

english, 2017

18

Effects of Fasting on Tissue Contents of Coenzyme A and Related Intermediates in Rats

Jenniskens, Floor A, Jopperi-Davis, Katrina S, Walters, Lauren C, Schorr, Erica N, Rogers, Lynette K, Welty, Stephen E, Smith, Charles V

Journal:

Pediatric Research

Year:

2002

Language:

english

File:

PDF, 634 KB

english, 2002

19

Widespread Translational Remodeling during Human Neuronal Differentiation

Blair, John D., Hockemeyer, Dirk, Doudna, Jennifer A., Bateup, Helen S., Floor, Stephen N.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.53 MB

english, 2017

20

The Traffic Jam: Polyamine Prevalence Pauses Protein Production

Venkataramanan, Srivats, Floor, Stephen N.

Journal:

Year:

2018

Language:

english

File:

PDF, 359 KB

english, 2018

21

CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway

Richardson, Chris D., Kazane, Katelynn R., Feng, Sharon J., Zelin, Elena, Bray, Nicholas L., Schäfer, Axel J., Floor, Stephen N., Corn, Jacob E.

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

22

The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA

Iwasaki, Shintaro, Iwasaki, Wakana, Takahashi, Mari, Sakamoto, Ayako, Watanabe, Chiduru, Shichino, Yuichi, Floor, Stephen N., Fujiwara, Koichi, Mito, Mari, Dodo, Kosuke, Sodeoka, Mikiko, Imataka, Hiro

Journal:

Year:

2018

Language:

english

File:

PDF, 5.07 MB

english, 2018

23

PTBP1 mRNA isoforms and regulation of their translation

Arake de Tacca, Luisa M, Pulos-Holmes, Mia C, Floor, Stephen N, Cate, Jamie H D

Journal:

Year:

2019

Language:

english

File:

PDF, 11.41 MB

english, 2019

24

STROOPWAFEL: Simulating rare outcomes from astrophysical populations, with application to gravitational-wave sources*

Broekgaarden, Floor S, Justham, Stephen, de Mink, Selma E, Gair, Jonathan, Mandel, Ilya, Stevenson, Simon, Barrett, Jim W, Vigna-Gómez, Alejandro, Neijssel, Coenraad J

Journal:

Monthly Notices of the Royal Astronomical Society

Year:

2019

Language:

english

File:

PDF, 72 KB

english, 2019

25

STROOPWAFEL: Simulating rare outcomes from astrophysical populations, with application to gravitational-wave sources*

Broekgaarden, Floor S, Justham, Stephen, de Mink, Selma E, Gair, Jonathan, Mandel, Ilya, Stevenson, Simon, Barrett, Jim W, Vigna-Gómez, Alejandro, Neijssel, Coenraad J

Journal:

Monthly Notices of the Royal Astronomical Society

Year:

2019

File:

PDF, 72 KB

2019

26

Retroperitoneal lymphatic malformation in a dog

Driessen, Floor, Cushing, Tim, Baines, Stephen John

Journal:

Acta Veterinaria Scandinavica

Year:

2020

Language:

english

File:

PDF, 1.50 MB

english, 2020

27

Common envelope episodes that lead to double neutron star formation

Vigna-GÃ³mez, Alejandro, MacLeod, Morgan, Neijssel, Coenraad J., Broekgaarden, Floor S., Justham, Stephen, Howitt, George, de Mink, Selma E., Vinciguerra, Serena, Mandel, Ilya

Journal:

Publications of the Astronomical Society of Australia

Year:

2020

File:

PDF, 1.43 MB

2020