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1

A quantitative study of the effect of process parameters on key granule characteristics in a high shear wet granulation process involving a two component pharmaceutical blend

Oka, Sarang, Kašpar, Ondřej, Tokárová, Viola, Sowrirajan, Koushik, Wu, Huiquan, Khan, Mansoor, Muzzio, Fernando, Štěpánek, František, Ramachandran, Rohit

Journal:

Advanced Powder Technology

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

2

An Extension of Olivier's Theorem

Frantisek Stepanek

Journal:

American Mathematical Monthly

Year:

1965

Language:

english

File:

PDF, 241 KB

english, 1965

3

Experimental and theoretical investigation of the reactive granulation of sodium carbonate with dodecyl-benzenesulfonic acid

Marek Schöngut, David Smrčka, František Štěpánek

Journal:

Chemical Engineering Science

Year:

2013

Language:

english

File:

PDF, 467 KB

english, 2013

4

The effects of improper mixing and preferential wetting of active and excipient ingredients on content uniformity in high shear wet granulation

Oka, Sarang, Emady, Heather, Kašpar, Ondřej, Tokárová, Viola, Muzzio, Fernando, Štěpánek, František, Ramachandran, Rohit

Journal:

Powder Technology

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

5

Effect of colloidal silica on rheological properties of common pharmaceutical excipients

Majerová, Diana, Kulaviak, Lukáš, Růžička, Marek, Štěpánek, František, Zámostný, Petr

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 953 KB

english, 2016

6

Analysis of the origins of content non-uniformity in high-shear wet granulation

Oka, Sarang, Smrčka, David, Kataria, Anjali, Emady, Heather, Muzzio, Fernando, Štěpánek, František, Ramachandran, Rohit

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 941 KB

english, 2017

7

Multi-Armed Droplets as Shape-Changing Protocells

Čejková, Jitka, Hanczyc, Martin M., Štěpánek, František

Journal:

Artificial Life

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

8

Design of granule structure: Computational methods and experimental realization

Mansoor A. Ansari, Frantisek Stepanek

Journal:

Year:

2006

Language:

english

File:

PDF, 677 KB

english, 2006

9

A study on adjusted contact force laws for accelerated large scale discrete element simulations

Harald Kruggel-Emden, Frantisek Stepanek, Ante Munjiza

Journal:

Year:

2010

Language:

english

File:

PDF, 2.54 MB

english, 2010

10

A mechanistic model for breakage in population balances of granulation: Theoretical kernel development and experimental validation

Rohit Ramachandran, Charles D. Immanuel, Frantisek Stepanek, James D. Litster, Francis J. Doyle III

Journal:

Chemical Engineering Research and Design

Year:

2009

Language:

english

File:

PDF, 2.42 MB

english, 2009

11

Microstructure-based mathematical modelling and spectroscopic imaging of tablet dissolution

James A. Kimber, Sergei G. Kazarian, František Štěpánek

Journal:

Computers & Chemical Engineering

Year:

2011

Language:

english

File:

PDF, 1.93 MB

english, 2011

12

Inkjet fabrication and characterization of calcium alginate microcapsules

Jiří Dohnal, František Štěpánek

Journal:

Powder Technology

Year:

2010

Language:

english

File:

PDF, 624 KB

english, 2010

13

Nonstationary operation of a system of catalytic monolithic reactors for selective NOx reduction

Jiřı́ Jirát, František Štěpánek, Milan Kubı́ček, Miloš Marek

Journal:

Chemical Engineering Science

Year:

1999

Language:

english

File:

PDF, 224 KB

english, 1999

14

Pore-scale modelling and tomographic visualisation of drying in granular media

Martin Kohout, Zdeněk Grof, František Štěpánek

Journal:

Journal of Colloid and Interface Science

Year:

2006

Language:

english

File:

PDF, 634 KB

english, 2006

15

Kinetics of Dry Neutralization of Dodecyl-Benzenesulfonic Acid with Respect to Detergent Granulation

Schöngut, Marek, Grof, Zdeněk, Štěpánek, František

Journal:

Industrial & Engineering Chemistry Research

Year:

2011

Language:

english

File:

PDF, 3.07 MB

english, 2011

16

Combined UV/vis and micro-tomography investigation of acetaminophen dissolution from granules

Kašpar, Ondřej, Tokárová, Viola, Oka, Sarang, Sowrirajan, Koushik, Ramachandran, Rohit, Štěpánek, František

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 4.67 MB

english, 2013

17

Quantitative validation and analysis of the regime map approach for the wet granulation of industrially relevant zirconium hydroxide powders

Adepu, Manogna, Hate, Siddhi, Bétard, Angelique, Oka, Sarang, Schongut, Marek, Sen, Maitraye, Sood, Yadvaindera, Wolf, Dorit, Wieland, Stefan, Stepanek, Frantisek, Muzzio, Fernando, Glasser, Benjamin,

Journal:

Powder Technology

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

18

Quantifying the effect of fillers on the breakage behaviour of needle-shaped particles

Grof, Zdeněk, Štěpánek, František

Journal:

Advanced Powder Technology

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

19

Effect of lipid nanoparticle formulations on skin delivery of a lipophilic substance

Vidlářová, Lucie, Hanuš, Jaroslav, Veselý, Martin, Ulbrich, Pavel, Štěpánek, František, Zbytovská, Jarmila

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.74 MB

english, 2016

20

The impact of polymeric excipients on the particle size of poorly soluble drugs after pH-induced precipitation

Punčochová, Kateřina, Prajzlerová, Marie, Beránek, Josef, Štěpánek, František

Journal:

European Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 808 KB

english, 2016

21

Scale-up from batch to flow-through wet milling process for injectable depot formulation

Lehocký, Róbert, Pěček, Daniel, Štěpánek, František

Journal:

European Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

22

[ASME ASME 2009 Pressure Vessels and Piping Conference - Prague, Czech Republic (July 26–30, 2009)] Volume 4: Fluid-Structure Interaction - Discrete Element Methods for Large Scale Particle/Fluid Simulations

Kruggel-Emden, Harald, Stepanek, Frantisek, Munjiza, Ante

Year:

2009

Language:

english

File:

PDF, 913 KB

english, 2009

23

Continuous production of spherical multi-crystals by extractive crystallization in a droplet based fluidic device

Kalný, Martin, Pittermannová, Anna, Zadražil, Aleš, Stepanek, Frantisek

Journal:

Crystal Growth & Design

Year:

2017

Language:

english

File:

PDF, 5.98 MB

english, 2017

24

Droplets As Liquid Robots

Čejková, Jitka, Banno, Taisuke, Hanczyc, Martin M., Štěpánek, František

Journal:

Artificial Life

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

25

A quantitative analysis of drug migration during granule drying

Kataria, Anjali, Oka, Sarang, Smrčka, David, Grof, Zdenek, Štěpánek, František, Ramachandran, Rohit

Journal:

Chemical Engineering Research and Design

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

26

Probing the early stages of tablet disintegration by stress relaxation measurement

Tomas, Jan, Schöngut, Marek, Dammer, Ondřej, Beránek, Josef, Zadražil, Aleš, Štěpánek, František

Journal:

European Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 6.70 MB

english, 2018

27

Manufacturing of Multi-drug Formulations with Customised Dose by Solvent Impregnation of Mesoporous Silica Tablets

Šoltys, Marek, Akhlasová, Sarah, Zadražil, Aleš, Kovačík, Pavel, Štěpánek, František

Journal:

AAPS PharmSciTech

Year:

2019

Language:

english

File:

PDF, 2.32 MB

english, 2019

28

Continuous high-shear granulation: Mechanistic understanding of the influence of process parameters on critical quality attributes via elucidating the internal physical and chemical microstructure

Meng, Wei, Dvořák, Jakub, Kumar, Ravish, Hofmeister, Rudy, Štěpánek, František, Ramachandran, Rohit, Muzzio, Fernando J.

Journal:

Advanced Powder Technology

Year:

2019

Language:

english

File:

PDF, 9.22 MB

english, 2019

29

Modeling capillary condensation hysteresis cycles in reconstructed porous media

František Štěpánek, Miloš Marek, Pierre M. Adler

Journal:

Year:

1999

Language:

english

File:

PDF, 466 KB

english, 1999

30

Multiscale modelling methodology for virtual prototyping of effervescent tablets

Frantisek Stepanek, Adeline Loo, Tiong Shing Lim

Journal:

Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 689 KB

english, 2006

31

Dye Diffusion in Polymer Films Subjected to Supercritical CO2: Confocal Raman Microscopy and Modelling

Oliver S. Fleming, Frantisek Stepanek, Sergei G. Kazarian

Journal:

Macromolecular Chemistry and Physics

Year:

2005

Language:

english

File:

PDF, 132 KB

english, 2005

32

Percolation models of adsorption–desorption equilibria and kinetics for systems with hysteresis

Miroslav Šoóš, Pavol Rajniak, František Štěpánek

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

33

Formation of hollow core granules by fluid bed in situ melt granulation: Modelling and experiments

Mansoor A. Ansari, Frantisek Stepanek

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 496 KB

english, 2006

34

Computational and experimental investigation of needle-shaped crystal breakage

Zdenĕk Grof, Carl M. Schoellhammer, Pavol Rajniak, František Štĕpánek

Journal:

International Journal of Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 783 KB

english, 2011

35

Characterization of copper SERS-active substrates prepared by electrochemical deposition

Jitka Cejkova, Vadym Prokopec, Sona Brazdova, Alzbeta Kokaislova, Pavel Matejka, Frantisek Stepanek

Journal:

Applied Surface Science

Year:

2009

Language:

english

File:

PDF, 424 KB

english, 2009

36

Dynamics and selectivity of NOx reduction in NOx storage catalytic monolith

Petr Kočí, František Plát, Jan Štěpánek, Milan Kubíček, Miloš Marek

Journal:

Catalysis Today

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

37

Global kinetic model for the regeneration of NOx storage catalyst with CO, H2 and C3H6 in the presence of CO2 and H2O

Petr Kočí, František Plát, Jan Štěpánek, Šárka Bártová, Miloš Marek, Milan Kubíček, Volker Schmeißer, Daniel Chatterjee, Michel Weibel

Journal:

Catalysis Today

Year:

2009

Language:

english

File:

PDF, 660 KB

english, 2009

38

Meso-scale modelling of CO oxidation in digitally reconstructed porous catalyst

Petr Kočí, František Štěpánek, Milan Kubíček, Miloš Marek

Journal:

Chemical Engineering Science

Year:

2006

Language:

english

File:

PDF, 738 KB

english, 2006

39

Multi-scale simulation of needle-shaped particle breakage under uniaxial compaction

Zdeněk Grof, Martin Kohout, František Štěpánek

Journal:

Chemical Engineering Science

Year:

2007

Language:

english

File:

PDF, 883 KB

english, 2007

40

Mathematical modelling of low-temperature hydrogen production with in situ CO2 capture

Georgios C. Koumpouras, Esat Alpay, Frantisek Stepanek

Journal:

Chemical Engineering Science

Year:

2007

Language:

english

File:

PDF, 630 KB

english, 2007

41

Fabrication of composite microcapsules by drop-on-demand inkjet: Effect of precursor composition on the process limits

Jiří Dohnal, František Štěpánek

Journal:

Chemical Engineering Science

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

42

Characterisation of porous media by the virtual capillary condensation method

František Štěpánek, Miroslav Šoóš, Pavol Rajniak

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Year:

2007

Language:

english

File:

PDF, 1.94 MB

english, 2007

43

Investigation of thermo-responsive optical properties of a composite hydrogel

Aleš Zadražil, František Štěpánek

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Year:

2010

Language:

english

File:

PDF, 789 KB

english, 2010

44

Investigation of combined DOC and NSRC diesel car exhaust catalysts

Jan Štěpánek, Petr Kočí, František Plát, Miloš Marek, Milan Kubíček

Journal:

Computers & Chemical Engineering

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

45

The strength of liquid bridges in random granular materials

Zdeněk Grof, Christopher J. Lawrence, František Štěpánek

Journal:

Journal of Colloid and Interface Science

Year:

2008

Language:

english

File:

PDF, 2.72 MB

english, 2008

46

Investigation of internal microstructure and thermo-responsive properties of composite PNIPAM/silica microcapsules

Jitka Čejková, Jaroslav Hanuš, František Štěpánek

Journal:

Journal of Colloid and Interface Science

Year:

2010

Language:

english

File:

PDF, 3.08 MB

english, 2010

47

Reversible buckling and diffusion properties of silica-coated hydrogel particles

Petra Haufová, Zdeněk Knejzlík, Jaroslav Hanuš, Aleš Zadražil, František Štěpánek

Journal:

Journal of Colloid and Interface Science

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

48

Synthesis, characterization and study of arsenate adsorption from aqueous solution by α- and δ-phase manganese dioxide nanoadsorbents

Mandeep Singh, Dong Nguyen Thanh, Pavel Ulbrich, Nina Strnadová, František Štěpánek

Journal:

Journal of Solid State Chemistry

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

49

A new traveling wave phenomenon of Dictyostelium in the presence of cAMP

Hana Ševčíková, Jitka Čejková, Lenka Krausová, Michal Přibyl, František Štěpánek, Miloš Marek

Journal:

Physica D: Nonlinear Phenomena

Year:

2010

Language:

english

File:

PDF, 4.77 MB

english, 2010

50

The effect of granule microstructure on dissolution rate

Mansoor A. Ansari, Frantisek Stepanek

Journal:

Powder Technology

Year:

2008

Language:

english

File:

PDF, 2.36 MB

english, 2008