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51

Mild phenotype and normal gonadal function in females with 4p trisomy due to unbalanced t(X;4)(p22.1;p14)

Paul Petit, Carl Hilliker, Fred Van Leuven, Jean-Pierre Fryns

Journal:

Clinical Genetics

Year:

1994

Language:

english

File:

PDF, 559 KB

english, 1994

52

Cultured human fibroblasts contain a large pool of precursor β1-integrin but lack an intracellular pool of mature subunit

Bart De STROOPER, Fred Van LEUVEN, Geert CARMELIET, Herman Van Den BERGHE, Jean-Jacques CASSIMAN

Journal:

Year:

1991

Language:

english

File:

PDF, 974 KB

english, 1991

53

The closely related homomeric and heterodimeric mannose-binding lectins from garlic are encoded by one-domain and two-domain lectin genes, respectively

Els J. M. VAN DAMME, Koen SMEETS, Sophie TORREKENS, Fred VAN LEUVEN, Irwin J. GOLDSTEIN, Willy J. PEUMANS

Journal:

Year:

1992

Language:

english

File:

PDF, 891 KB

english, 1992

54

Isolation and characterization of alliinase cDNA clones from garlic (Allium sativum L.) and related species

Els J. M. VAN DAMME, Koen SMEETS, Sophie TORREKENS, Fred VAN LEUVEN, Willy J. PEUMANS

Journal:

Year:

1992

Language:

english

File:

PDF, 712 KB

english, 1992

55

The primary sequence and the subunit structure of mouse α-2-macroglobulin, deduced from protein sequencing of the isolated subunits and from molecular cloning of the cDNA

Fred VAN LEUVEN, Sophie TORREKENS, Lut OVERBERGH, Kristin LORENT, Bart DE STROOPER, Herman VAN DEN BERGHE

Journal:

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

56

The mannose-specific lectins from ramsons (Allium ursinum L.) are encoded by three sets of genes

Els J. M. VAN DAMME, Koen SMEETS, Sophie TORREKENS, Fred VAN LEUVEN, Willy J. PEUMANS

Journal:

Year:

1993

Language:

english

File:

PDF, 772 KB

english, 1993

57

Characterization and molecular cloning of mannose-binding lectins from the Orchidaceae species Listera ovata, Epipactis helleborine and Cymbidium hybrid

Els J. M. VAN DAMME, Koen SMEETS, Sophie TORREKENS, Fred VAN LEUVEN, Willy J. PEUMANS

Journal:

Year:

1994

Language:

english

File:

PDF, 1.27 MB

english, 1994

58

The NeuAc(α-2,6)-Gal/GalNAc-Binding Lectin from Elderberry (Sambucus Nigra) Bark, a type-2 Ribosome-Inactivating Protein with an Unusual Specificity and Structure

Els J. M. Van Damme, Annick Barre, Pierre Rougé, Fred Van Leuven, Willy J. Peumans

Journal:

Year:

1996

Language:

english

File:

PDF, 1.28 MB

english, 1996

59

Molecular Cloning of Two Different Mannose-Binding Lectins from Tulip Bulbs

Els J. M. Van Damme, Filip Briké, Harry C. Winter, Fred Van Leuven, Irwin J. Goldstein, Willy J. Peumans

Journal:

Year:

1996

Language:

english

File:

PDF, 1.13 MB

english, 1996

60

Rat Pristanoyl-CoA Oxidase : cDNA Cloning and Recognition of its C-Terminal (SQL) by the Peroxisomal-Targeting Signal 1 Receptor

Johannes C. T. Vanhooren, Marc Fransen, Bernadette De Béthune, Eveline Baumgart, Myriam Baes, Sophie Torrekens, Fred Van Leuven, Guy P. Mannaerts, Paul P. Van Veldhoven

Journal:

Year:

1996

Language:

english

File:

PDF, 1.07 MB

english, 1996

61

Characterization and Molecular Cloning of Sambucus nigra Agglutinin V (Nigrin b), A Galnac-specific Type-2 Ribosome-Inactivating Protein from the Bark of Elderberry (Sambucus nigra)

Els J. M. van Damme, Annick Barre, Pierre Rougé, Fred van Leuven, Willy J. Peumans

Journal:

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

62

Elderberry (Sambucus Nigra) Bark Contains two Structurally Different Neusac(α2,6)Gal/Galnac-Binding Type 2 Ribosome-Inactivating Proteins

Els J. M. VAN Damme, Soma Roy, Annick Barre, Lucia Citores, Kazem Mostafapous, Pierre Rougé, Fred VAN Leuven, Tomas Girbés, Irwin J. Goldstein, Willy J. Peumans

Journal:

Year:

1997

Language:

english

File:

PDF, 939 KB

english, 1997

63

Abnormal Glutamate Transport Function in Mutant Amyloid Precursor Protein Transgenic Mice

Eliezer Masliah, Michael Alford, Margaret Mallory, Edward Rockenstein, Dieder Moechars, Fred Van Leuven

Journal:

Experimental Neurology

Year:

2000

Language:

english

File:

PDF, 284 KB

english, 2000

64

Genomic Cloning of the Mouse LDL Receptor Related Protein/α2-Macroglobulin Receptor Gene

André van der Zee, Lou Stas, Carl Hilleker, Fred Van Leuven, Ko Willems van Dijk, Louis Havekes, Rune Frants, Marten Hofker

Journal:

Year:

1994

File:

PDF, 250 KB

1994

65

Molecular Cloning and Characterization of the Human Interleukin-11 Receptor α-Chain Gene, IL11RA, Located on Chromosome 9p13

Fred Van Leuven, Lou Stas, Carl Hilliker, Yoshimasa Miyake, Petra Bilinski, Achim Gossler

Journal:

Year:

1996

Language:

english

File:

PDF, 134 KB

english, 1996

66

Analysis of the Human LRPAP1 Gene Coding for the Lipoprotein Receptor-Associated Protein: Identification of 22 Polymorphisms and One Mutation

Fred Van Leuven, Els Thiry, Lou Stas, Bart Nelissen

Journal:

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

67

Molecular Cloning of a Gene on Chromosome 19q12 Coding for a Novel Intracellular Protein: Analysis of Expression in Human and Mouse Tissues and in Human Tumor Cells, Particularly Reed–Sternberg Cells in Hodgkin Disease

Fred Van Leuven, Sophie Torrekens, Dieder Moechars, Carl Hilliker, Monique Buellens, Mathieu Bollen, Jan Delabie

Journal:

Year:

1998

Language:

english

File:

PDF, 1.14 MB

english, 1998

68

Acetylcholinesterase-Positive Fiber Deafferentation and Cell Shrinkage in the Septohippocampal Pathway of Aged Amyloid Precursor Protein London Mutant Transgenic Mice

Francisca C. Bronfman, Dieder Moechars, Fred Van Leuven

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 713 KB

english, 2000

69

Acetylcholinesterase-Positive Fiber Deafferentation and Cell Shrinkage in the Septohippocampal Pathway of Aged Amyloid Precursor Protein London Mutant Transgenic Mice: Volume 7, Number 3 (2000), pages 152–168

Francisca C. Bronfman, Dieder Moechars, Fred Van Leuven

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 10 KB

english, 2000

70

Evidence for a role of fibronectin and other cell surface components in cell-cell layer adhesion of human fibroblasts

Marc Saison, Fred Van Leuven, Jean-Jacques Cassiman, Herman Van Den Berghe

Journal:

Experimental Cell Research

Year:

1983

Language:

english

File:

PDF, 1.36 MB

english, 1983

71

Receptor-mediated endocytosis of α2macroglobulin—protease complexes by fibroblasts in culture: Competitive inhibition by bacitracin

Fred Van Leuven, Peter Marynen, Jean-Jacques Cassiman, Herman van den Berghe

Journal:

Year:

1981

Language:

english

File:

PDF, 400 KB

english, 1981

72

Proteolysis at a lysine residue abolishes the recetor-recognition site of α2-Macroglobulin complexes

Peter Marynen, Fred Van Leuven, Jean-Jacques Cassiman, Herman Van Den Berghe

Journal:

Year:

1982

Language:

english

File:

PDF, 789 KB

english, 1982

73

Domain structure of human α2-macroglobulin: Characterization of a receptor-binding domain obtained by digestion with papain

Lars Sottrup-Jensen, Jørgen Gliemann, Fred Van Leuven

Journal:

Year:

1986

Language:

english

File:

PDF, 507 KB

english, 1986

74

Post-translational modification of the β-subunit of the human fibronectin receptor

Martine Jaspers, Bart de Strooper, Marijke Spaepen, Fred van Leuven, Guido David, Herman van den Berghe, Jean-Jacques Cassiman

Journal:

Year:

1988

Language:

english

File:

PDF, 1.05 MB

english, 1988

75

α2-Macroglobulin and other proteinase inhibitors do not interfere with the secretion of amyloid precursor protein in mouse neuroblastoma cells

Bart De Strooper, Fred Van Leuven, Herman Van Den Berghe

Journal:

Year:

1992

Language:

english

File:

PDF, 442 KB

english, 1992

76

A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species

Franky R.G. Terras, Sophie Torrekens, Fred Van Leuven, Rupert W. Osborn, Jozef Vanderleyden, Bruno P.A. Cammue, Willem F. Broekaert

Journal:

Year:

1993

Language:

english

File:

PDF, 941 KB

english, 1993

77

Isolation, characterization and partial sequencing of Pregnancy Associated Mouse Protein PAMP1 identifies it as a novel female specific protein, unrelated to the α-2-macroglobulin family of proteinase inhibitors

Fred Van Leuven, Sophie Torrekens, Herman Van den Berghe

Journal:

Year:

1993

Language:

english

File:

PDF, 617 KB

english, 1993

78

Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae

Rupert W. Osborn, Genoveva W. De Samblanx, Karin Thevissen, Inge Goderis, Sophie Torrekens, Fred Van Leuven, Sheila Attenborough, Sarah B. Rees, Willem F. Broekaert

Journal:

Year:

1995

Language:

english

File:

PDF, 603 KB

english, 1995

79

Dendritic Degeneration, Neurovascular Defects, and Inflammation Precede Neuronal Loss in a Mouse Model for Tau-Mediated Neurodegeneration

Tomasz Jaworski, Benoit Lechat, David Demedts, Lies Gielis, Herman Devijver, Peter Borghgraef, Hans Duimel, Fons Verheyen, Sebastian Kügler, Fred Van Leuven

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 6.01 MB

english, 2011

80

A yeast-based model of α-synucleinopathy identifies compounds with therapeutic potential

Gerard Griffioen, Hein Duhamel, Nele Van Damme, Klaartje Pellens, Piotr Zabrocki, Christophe Pannecouque, Fred van Leuven, Joris Winderickx, Stefaan Wera

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2006

Language:

english

File:

PDF, 335 KB

english, 2006

81

Alzheimer's disease: Old problem, new views from transgenic and viral models

Tomasz Jaworski, Ilse Dewachter, Claire Marie Seymour, Peter Borghgraef, Herman Devijver, Sebastian Kügler, Fred Van Leuven

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2010

Language:

english

File:

PDF, 1.82 MB

english, 2010

82

Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells

Lut Van Laer, Markus Pfister, Sofie Thys, Karen Vrijens, Marcus Mueller, Lieve Umans, Lutgarde Serneels, Luc Van Nassauw, Frank Kooy, Richard J.H. Smith, Jean-Pierre Timmermans, Fred Van Leuven, Guy V

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 704 KB

english, 2005

83

Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo

Chiho Hirata-Fukae, Elkhansa Hassan Sidahmed, Thomas P. Gooskens, Paul S. Aisen, Ilse Dewachter, Herman Devijver, Fred Van Leuven, Yasuji Matsuoka

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 322 KB

english, 2008

84

Occurrence and co-localization of amyloid β-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice

Dietmar Rudolf Thal, Sergey Larionov, Dorothee Abramowski, Karl-Heinz Wiederhold, Tom Van Dooren, Haruyasu Yamaguchi, Christian Haass, Fred Van Leuven, Matthias Staufenbiel, Estibaliz Capetillo-Zarate

Journal:

Neurobiology of Aging

Year:

2007

Language:

english

File:

PDF, 1.51 MB

english, 2007

85

Potential amyloid plaque-specific peptides for the diagnosis of Alzheimer's disease

Lionel Larbanoix, Carmen Burtea, Sophie Laurent, Fred Van Leuven, Gérard Toubeau, Luce Vander Elst, Robert N. Muller

Journal:

Neurobiology of Aging

Year:

2010

Language:

english

File:

PDF, 2.91 MB

english, 2010

86

β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Increases Amyloid Deposition in Brain Parenchyma but Reduces Cerebrovascular Amyloid Angiopathy in Aging BACE × APP[V717I] Double-Transgenic Mice

Michael Willem, Ilse Dewachter, Neil Smyth, Tom Van Dooren, Peter Borghgraef, Christian Haass, Fred Van Leuven

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 1.00 MB

english, 2004

87

Prominent Axonopathy and Disruption of Axonal Transport in Transgenic Mice Expressing Human Apolipoprotein E4 in Neurons of Brain and Spinal Cord

Ina Tesseur, Jo Van Dorpe, Koen Bruynseels, Francisca Bronfman, Raf Sciot, Alfons Van Lommel, Fred Van Leuven

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 3.54 MB

english, 2000

88

Expression of Human Apolipoprotein E4 in Neurons Causes Hyperphosphorylation of Protein Tau in the Brains of Transgenic Mice

Ina Tesseur, Jo Van Dorpe, Kurt Spittaels, Chris Van den Haute, Dieder Moechars, Fred Van Leuven

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 3.20 MB

english, 2000

89

α2-Macroglobulin- and Murinoglobulin-1- Deficient Mice: A Mouse Model for Acute Pancreatitis

Lieve Umans, Lutgarde Serneels, Lut Overbergh, Lou Stas, Fred Van Leuven

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 1.36 MB

english, 1999

90

Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein

Kurt Spittaels, Chris Van den Haute, Jo Van Dorpe, Koen Bruynseels, Kris Vandezande, Isabelle Laenen, Hugo Geerts, Marc Mercken, Raf Sciot, Alfons Van Lommel, Ruth Loos, Fred Van Leuven

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 2.17 MB

english, 1999

91

Elderberry (Sambucus nigra) contains truncated Neu5Ac(α-2,6)Gal/GalNAc-binding type 2 ribosome-inactivating proteins

Willy J Peumans, Soma Roy, Annick Barre, Pierre Rouge, Fred van Leuven, Els J.M van Damme

Journal:

Year:

1998

Language:

english

File:

PDF, 215 KB

english, 1998

92

Alpha-2-macroglobulin receptor is differently expressed in peritoneal macrophages from C3H and C57/B16 mice and up-regulated during Trypanosoma cruzi infection

Cláudia M.L.M. Coutinho, Guarani Cavalcanti, Renato A. DaMatta, Fred Van Leuven, Tania C. Araújo-Jorge

Journal:

Tissue and Cell

Year:

1998

Language:

english

File:

PDF, 4.46 MB

english, 1998

93

Transgenic mice expressing an α-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder

Dieder Moechars, Kristin Lorent, Ilse Dewachter, Veerle Baekelandt, Bart De Strooper, Fred Van Leuven

Journal:

Behavioural Brain Research

Year:

1998

Language:

english

File:

PDF, 858 KB

english, 1998

94

Neuronal expression of human apolipoprotein E4 increases protein tau phosphorylation in transgenic mice

Ina C. Tesseur, Jo Van Dorpe, Kurt Spittaels, Chris Van den Haute, Koen Bruynseels, Fred Van Leuven

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

95

Impact of PS mutations and PS null state in adult transgenic mouse brain

Fred Van Leuven

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

96

Rescue of protein tau-induced axonopathy by GSK-3β in [GSK-3β X HTAU-4R] double transgenic mice

Kurt Spittaels, Chris Van Den Haute, Jo Van Dorpe, Hugo Geerts, Marc Mercken, Reena Lasrado, Kris Vandezande, Fred Van Leuven

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

97

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons

Jo A. Van Dorpe, Liesbet Smeijers, Ilse Dewachter, Spittaels Kurt, Chris Van Den Haute, Ina Tesseur, Raf Sciot, Fred Van Leuven

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

98

O1-01-07 Multiple transgenic mice, better models for AD?

Fred Van Leuven, Ilse Dewachter, Dick Terwel, Reena Lasrado, David Muyllaert, Ingrid Van der Auwera, Stefaan Wera

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 166 KB

english, 2004

99

Reduction of β-amyloid plaques in brain of transgenic mouse model of Alzheimer’s disease by EFRH-phage immunization

Dan Frenkel, Ilse Dewachter, Fred Van Leuven, Beka Solomon

Journal:

Year:

2003

Language:

english

File:

PDF, 216 KB

english, 2003

100

Single and multiple transgenic mice as models for Alzheimer’s disease

Fred van Leuven

Journal:

Progress in Neurobiology

Year:

2000

Language:

english

File:

PDF, 118 KB

english, 2000