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101

Parkin acts as a transcription factor modulating presenilin-1 and presenilin-2 promoter transactivations

Duplan, Eric, Sévalle, Jean, Viotti, Julien, Goiran, Thomas, Bauer, Charlotte, Renbaum, Paul, Levy-Lahad, Ephrat, Gautier, Clément A, Corti, Olga, Leroudier, Nathalie, Checler, Frédéric, da Costa, Cri

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 87 KB

english, 2013

102

The beta-secretase-derived C-terminal fragment of APP (C99): a key determinant for intraneuronal pathology in the 3xTgAD mouse

Lauritzen, Inger, Pardossi-Piquard, Raphaelle, Druon, Charlotte, Brigham, Elizabeth, Abraham, Daniel, Ranaldi, Sébatien, Chami, Linda, Dunys, Julie, Checler, Fréderic

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

103

Leaky Ryanodine receptors increases Amyloid-beta load and induces memory impairments in Tg2576 mouse model of Alzheimer disease

Oulès, Bénédicte, Del Prete, Dolores, Greco, Barbara, Zhang, Xuexin, Lauritzen, Inger, Trebak, Mohamed, Benfenati, Fabio, Checler, Frédéric, Chami, Mounia

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 84 KB

english, 2013

104

The transcription factor XBP-1 in neurodegenerative diseases

Frédéric Checler,Eric Duplan,Cristine Alves da Costa

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 74 KB

english, 2013

105

Neurotensin metabolism in various tissues of central and peripheral origins: ubiquitous involvement of a novel neurotensin degrading metalloendopeptidase

Checler, Frédéric, Barelli, Hélène, Kitabgi, Patrick, Vincent, Jean-Pierre

Journal:

Year:

1988

Language:

english

File:

PDF, 711 KB

english, 1988

106

P3-381 Endocytosis-dependent function of cellular prion

Sunyach, Claire, Checler, Frédéric

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

107

Study on Aβ34 biology and detection in transgenic mice brains

Caillava, Céline, Ranaldi, Sébastien, Lauritzen, Inger, Bauer, Charlotte, Fareh, Jeannette, Abraham, Jean-Daniel, Checler, Frédéric

Journal:

Neurobiology of Aging

Year:

2014

Language:

english

File:

PDF, 2.15 MB

english, 2014

108

p53 in neurodegenerative diseases and brain cancers

Checler, Frédéric, Alves da Costa, Cristine

Journal:

Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 689 KB

english, 2014

109

γ-secretase composition and cellular trafficking

Meckler, Xavier, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

110

Author index

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Journal of Biotechnology

Year:

1990

Language:

english

File:

PDF, 144 KB

english, 1990

111

Diary of the Week

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Year:

1982

Language:

english

File:

PDF, 143 KB

english, 1982

112

P3-237

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

113

ROYAL COLLEGE OF SURGEONS OF ENGLAND.

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Year:

1868

Language:

english

File:

PDF, 874 KB

english, 1868

114

Regulation of the amyloid precursor protein processing by the Nuclear Factor-kappa B

Chami, Linda, Buggia-Prevot, Virginie, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

115

Analogues radioactifs de la neurotensine. II. Préparation de neurotensine tritiée à partir d'un dérivé multi-insaturé de synthèse

Labbé-Jullié, Catherine, Blanot, Didier, Morgat, Jean-Louis, Kitabgi, Patrick, Checler, Frédéric, Vincent, Jean-Pierre, Granier, Claude, Van Rietschoten, Jurphaas

Journal:

Year:

1983

Language:

english

File:

PDF, 796 KB

english, 1983

116

Characterization of a new ADAM as a key player of the APP metabolism

Letronne, Florent, Laumet, Geoffroy, Demiautte, Florie, Colin, Morvane, Ayral, Anne-Marie, Hot, David, Hansmannel, Franck, Mounier, Anais, Berr, Claudine, Huot, Ludovic, Checler, Frederic, Pasquier, F

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

117

Apathy-like syndrome associated with early lesion in the triple-transgenic 3xTgAD mouse

Lauritzen, Inger, Pardossi-Piquard, Raphaelle, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

118

Further characterization of a neurotensin-degrading neutral metalloendopeptidase from rat brain

Barelli, Hélène, Girard, Fernand, St. Pierrr, Serge, Kitabgi, Patrick, Vincent, Jean-Pierre, Checler, Frédéric

Journal:

Neurochemistry International

Year:

1988

Language:

english

File:

PDF, 681 KB

english, 1988

119

Neuropeptide-hydrolysing activities in synaptosomal fractions from dog ileum myenteric, deep muscular and submucous plexi. Their participation in neurotensin inactivation

Barelli, Hélène, Ahmad, Sultan, Kostka, Peter, Fox, Jo-Ann E.T., Daniel, Edwin E., Vincent, Jean-Pierre, Checler, Frédéric

Journal:

Year:

1989

Language:

english

File:

PDF, 686 KB

english, 1989

120

Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein

Peuchmaur, Marine, Lacour, Marie-Agnès, Sévalle, Jean, Lisowski, Vincent, Touati-Jallabe, Youness, Rodier, Fabien, Martinez, Jean, Checler, Frédéric, Hernandez, Jean-François

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 854 KB

english, 2013

121

P3-213

Dunys, Julie, Kawarai, Toshitaka, St. George-Hyslop, Peter, Alves da Costa, Cristine, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

122

AICD is preferentially produced from C99 in a gamma-secretase in vitro assay

Flammang, Brice, Pardossi-Piquard, Raphaelle, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

123

identification of enzymes involved in n-terminal truncation and modification of amyloid peptide

Caillava, Celine, Sevalle, Jean, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

124

P3-238

Sévalle, Jean, Eyral, Erwan, Hernandez, Jean-François, Martinez, Jean, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

125

P3-225

Alves da Costa, Cristine, Sunyach, Claire, Pardossi-Piquard, Raphaelle, Vincent, Bruno, Sevalle, Jean, Kawarai, Toshitaka, St. George-Hyslop, Peter, Shen, Jie, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 70 KB

english, 2006

126

P4-219: TMP21 association with the γ-secretase complex and its regulation of protease activity

Pardossi-Piquard, Raphaelle, Chen, Fusheng, Bohm, Christopher, Checler, Frédéric, St George-Hyslop, Peter, Fraser, Paul

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

127

P1-449: Aminopeptidase A is involved in amyloid beta peptide N-terminal truncation

Sévalle, Jean, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

128

Catabolism of neurotensin by neural (neuroblastoma clone N1E115) and extraneural (HT29) cell lines

Checler, Frédéric, Amar, Shimon, Kitabgi, Patrick, Vincent, Jean-Pierre

Journal:

Year:

1986

Language:

english

File:

PDF, 710 KB

english, 1986

129

P3-243

Vincent, Bruno, Cissé, Moustapha, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

130

Early accumulation of C99 in 3xTg mice

Pardossi-Piquard, Raphaëlle, Lauritzen, Inger, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011

131

Assessment of BIN1 involvement in the Alzheimer's Disease pathophysiological process

Hansmannel, Franck, Mounier, Anais, Gistelinck, Marc, Grenier-Boley, Benjamin, Maturski, Marie Eve, Letronne, Florent, Ayral, Anne-Marie, Checler, Frederic, Buée, Luc, Amouyel, Philippe, Dermaut, Bart

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 74 KB

english, 2011

132

Endoplasmic Reticulum and Trans-Golgi Network Generate Distinct Populations of Alzheimer β -Amyloid Peptides

Jeffrey P. Greenfield, Julia Tsai, Gunnar K. Gouras, Bing Hai, Gopal Thinakaran, Frederic Checler, Sangram S. Sisodia, Paul Greengard and Huaxi Xu

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.90 MB

english, 1999

133

Presenilin 2 Deficiency Causes a Mild Pulmonary Phenotype and no Changes in Amyloid Precursor Protein Processing but Enhances the Embryonic Lethal Phenotype of Presenilin 1 Deficiency

An Herreman, Dieter Hartmann, Wim Annaert, Paul Saftig, Katleen Craessaerts, Lutgarde Serneels, Lieve Umans, Vincent Schrijvers, Frederic Checler, Hugo Vanderstichele, Veerle Baekelandt, Ralf Dressel,

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.62 MB

english, 1999

134

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

Dolores Del Prete,Frédéric Checler,Mounia Chami

Journal:

Molecular Neurodegeneration

Year:

2014

Language:

english

File:

PDF, 871 KB

english, 2014

135

Eph receptors: New players in Alzheimer's disease pathogenesis

Cissé, Moustapha, Checler, Frédéric

Journal:

Neurobiology of Disease

Year:

2015

Language:

english

File:

PDF, 909 KB

english, 2015

136

Confocal Microscopy Reveals Thimet Oligopeptidase (EC 3.4.24.15) and Neurolysin (EC 3.4.24.16) in the Classical Secretory Pathway

Garrido, Paula A.G., Vandenbulcke, Franck, Ramjaun, Antoine R., Vincent, Bruno, Checler, Frederic, Ferro, Emer, Beaudet, Alain

Journal:

DNA and Cell Biology

Year:

1999

Language:

english

File:

PDF, 503 KB

english, 1999

137

Melatonin stimulates the nonamyloidogenic processing of β APP through the positive transcriptional regulation of ADAM10 and ADAM17

Shukla, Mayuri, Htoo, Htut Htut, Wintachai, Phitchayapak, Hernandez, Jean-Francois, Dubois, Claire, Postina, Rolf, Xu, Huaxi, Checler, Frédéric, Smith, Duncan R., Govitrapong, Piyarat, Vincent, Bruno

Journal:

Journal of Pineal Research

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

138

Two-steps control of cellular prion physiology by the Extracellular Regulated Kinase-1 (ERK1)

Checler, Frédéric

Journal:

Year:

2012

Language:

english

File:

PDF, 377 KB

english, 2012

139

Experimental stroke: neurolysin back on stage

Checler, Frédéric

Journal:

Journal of Neurochemistry

Year:

2014

Language:

english

File:

PDF, 235 KB

english, 2014

140

The transcription factor X-box binding protein-1 in neurodegenerative diseases

Dunys, Julie, Duplan, Eric, Checler, Frédéric

Journal:

Molecular Neurodegeneration

Year:

2014

Language:

english

File:

PDF, 381 KB

english, 2014

141

A novel parkin-mediated transcriptional function links p53 to familial Parkinson’s disease

Alves da Costa, Cristina, Checler, Frédéric

Journal:

Year:

2010

Language:

english

File:

PDF, 668 KB

english, 2010

142

Presenilins: Multifunctional Proteins Involved in Alzheimer's Disease Pathology

Checler, Frederic

Journal:

Year:

1999

Language:

english

File:

PDF, 165 KB

english, 1999

143

α-Secretase in Alzheimers Disease and Beyond: Mechanistic, Regulation and Function in the Shedding of Membrane Proteins

Vincent, Bruno, Checler, Frederic

Journal:

Current Alzheimer Research

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

144

The γ /η-Secretase-Derived APP Intracellular Domain Fragments Regulate p53

Checler, Frederic, Sunyach, Claire, Pardossi-Piquard, Raphaelle, Sevalle, Jean, Vincent, Bruno, Kawarai, Toshitaka, Girardot, Nadege, George-Hyslop, Peter St, da Costa, Cristine

Journal:

Current Alzheimer Research

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

145

Editorial [ Production and Fate of Amyloid Peptides: Recent Advances and Perspectives ]

Checler, Frederic

Journal:

Current Alzheimer Research

Year:

2008

Language:

english

File:

PDF, 163 KB

english, 2008

146

Regulation of βAPP and PrPc Cleavage by α-Secretase: Mechanistic and Therapeutic Perspectives

Vincent, Bruno, Cisse, Moustapha, Sunyach, Claire, Guillot-Sestier, Marie-Victoire, Checler, Frederic

Journal:

Current Alzheimer Research

Year:

2008

Language:

english

File:

PDF, 234 KB

english, 2008

147

JLK Inhibitors: Isocoumarin Compounds as Putative Probes to Selectively Target the γ-Secretase Pathway

Frederic, Checler, Cristine, Alves, Erwan, Ayral, David, Andrau, Cecile, Dumanchin, Michael, Farzan, Jean-Francois, Hernandez, Martinez, J., Solveig, Lefranc-Jullien, Philippe, Marambaud, Andrea, Pasi

Journal:

Current Alzheimer Research

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

148

Ryanodine receptors

Chami, Mounia, Checler, Frédéric

Journal:

Year:

2014

Language:

english

File:

PDF, 421 KB

english, 2014

149

p53 Is Regulated by and Regulates Members of the γ-Secretase Complex

Checler, Frédéric, Dunys, Julie, Pardossi-Piquard, Raphaelle, Alves da Costa, Cristine

Journal:

Neurodegenerative Diseases

Year:

2010

Language:

english

File:

PDF, 235 KB

english, 2010

150

Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments

Meckler, Xavier, Checler, Frédéric

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 10.31 MB

english, 2016