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51

Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats

M. Jeub, H. Beck, E. Siep, C. Rüschenschmidt, E.-J. Speckmann, U. Ebert, H. Potschka, C. Freichel, E. Reissmüller, W. Löscher

Journal:

Neuropharmacology

Year:

2002

Language:

english

File:

PDF, 186 KB

english, 2002

52

A new oral erosion controlled drug delivery system with a late burst in the release profile

Oliver L. Freichel, Bernhard C. Lippold

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2000

Language:

english

File:

PDF, 380 KB

english, 2000

53

Mechanism of Stretch-Induced Activation of the Mechanotransducer Zyxin in Vascular Cells

Suresh Babu, S., Wojtowicz, A., Freichel, M., Birnbaumer, L., Hecker, M., Cattaruzza, M.

Journal:

Science Signaling

Year:

2012

Language:

english

File:

PDF, 4.44 MB

english, 2012

54

The TRPV6 gene, cDNA and protein

Daniela Hirnet, Jenny Olausson, Claudia Fecher-Trost, Matthias Bödding, Wolfgang Nastainczyk, Ulrich Wissenbach, Veit Flockerzi, Marc Freichel

Journal:

Year:

2003

Language:

english

File:

PDF, 453 KB

english, 2003

55

P.3.d.016 Effects of aripiprazole/OPC-14597 on pharmacological models of psychosis in rats

R.E. Nordquist, M. Maco, C. Freichel, C. Riemer, W.P. Spooren

Journal:

European Neuropsychopharmacology

Year:

2006

Language:

english

File:

PDF, 61 KB

english, 2006

56

Deletion of TRPC4 and TRPC6 in Mice Impairs Smooth Muscle Contraction and Intestinal Motility In Vivo

Volodymyr V. Tsvilovskyy, Alexander V. Zholos, Thomas Aberle, Stephan E. Philipp, Alexander Dietrich, Michael X. Zhu, Lutz Birnbaumer, Marc Freichel, Veit Flockerzi

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

57

Canonical Transient Receptor Channel 5 (TRPC5) and TRPC1/4 Contribute to Seizure and Excitotoxicity by Distinct Cellular Mechanisms

Phelan, K. D., Shwe, U. T., Abramowitz, J., Wu, H., Rhee, S. W., Howell, M. D., Gottschall, P. E., Freichel, M., Flockerzi, V., Birnbaumer, L., Zheng, F.

Journal:

Molecular Pharmacology

Year:

2013

Language:

english

File:

PDF, 2.00 MB

english, 2013

58

Light Induced Functionalization of PCL-PEG Block Copolymers for the Covalent Immobilization of Biomolecules

Pourcelle, Vincent, Freichels, Hélène, Stoffelbach, François, Auzély-Velty, Rachel, Jérôme, Christine, Marchand-Brynaert, Jacqueline

Journal:

Biomacromolecules

Year:

2009

Language:

english

File:

PDF, 972 KB

english, 2009

59

Synaptobrevin2 is the v-SNARE required for cytotoxic T-lymphocyte lytic granule fusion

Matti, Ulf, Pattu, Varsha, Halimani, Mahantappa, Schirra, Claudia, Krause, Elmar, Liu, Yuanyuan, Weins, Lisa, Fang Chang, Hsin, Guzman, Raul, Olausson, Jenny, Freichel, Marc, Schmitz, Frank, Pasche, M

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 952 KB

english, 2013

60

Fluorescent labeling of degradable poly(lactide-co-glycolide) for cellular nanoparticles tracking in living cells

Freichels, Hélène, Danhier, Fabienne, Préat, Véronique, Lecomte, Philippe, Jérôme, Christine

Journal:

The International Journal of Artificial Organs

Year:

2011

Language:

english

File:

PDF, 267 KB

english, 2011

61

Easy functionalization of amphiphilic poly(ethylene oxide)-b-poly(ε-caprolactone) copolymer micelles with unprotected sugar: synthesis and recognition by lectins

Freichels, Hélène, Auzély-Velty, Rachel, Lecomte, Philippe, Jérôme, Christine

Journal:

Polymer Chemistry

Year:

2012

Language:

english

File:

PDF, 474 KB

english, 2012

62

(Oligo)mannose functionalized hydroxyethyl starch nanocapsules: en route to drug delivery systems with targeting properties

Freichels, Hélène, Wagner, Manfred, Okwieka, Patricia, Meyer, Ralf Georg, Mailänder, Volker, Landfester, Katharina, Musyanovych, Anna

Journal:

Journal of Materials Chemistry B

Year:

2013

Language:

english

File:

PDF, 659 KB

english, 2013

63

Characterisation of explanted endothelial cells from mouse aorta: electrophysiology and Ca2+signalling

S.H. Suh, R. Vennekens, V.G. Manolopoulos, M. Freichel, U. Schweig…

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 384 KB

english, 1999

64

Increased -Adrenergic Inotropy in Ventricular Myocardium From Trpm4-/- Mice

Mathar, I., Kecskes, M., Van der Mieren, G., Jacobs, G., Camacho Londono, J. E., Uhl, S., Flockerzi, V., Voets, T., Freichel, M., Nilius, B., Herijgers, P., Vennekens, R.

Journal:

Circulation Research

Year:

2014

Language:

english

File:

PDF, 2.42 MB

english, 2014

65

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

Schattling, Benjamin, Steinbach, Karin, Thies, Edda, Kruse, Martin, Menigoz, Aurélie, Ufer, Friederike, Flockerzi, Veit, Brück, Wolfgang, Pongs, Olaf, Vennekens, Rudi, Kneussel, Matthias, Freichel, Ma

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

66

Evidence for functional coupling of cGMP/cGKI signalling and TRPC channels in endothelium but not in vascular smooth muscle

Florian Loga,Katrin Domes,Marc Freichel…

Journal:

BMC Pharmacology and Toxicology

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

67

TRPC1 and TRPC4 Channels Contribute to Basal Cardiac Calcium Signalling via a Constitutively Active Background Calcium Entry

Lipp, Peter, Tian, Qinghai, Oberhofer, Martin, Hammer, Karin, Camacho-Londono, Juan E., Weissgerber, Petra, Freichel, Marc, Kaestner, Lars

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 39 KB

english, 2012

68

Lysophosphatidic Acid Signalling in Red Blood Cells

Kaestner, Lars, Wang, Jue, Wagner-Britz, Lisa, Bogdanova, Anna, Wiesen, Kathrina, Tian, Qinghai, Bernhardt, Ingolf, Philipp, Stephan, Freichel, Marc, Flockerzi, Veit, Lipp, Peter

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

69

Excision of the Cacnb2 Gene in Mice Results in Augmented SR-Ca Release and Impaired Cardiac Function In Vivo

Lipp, Peter, Wiesen, Kathrina, Pahlavan, Sara, Tian, Qinghai, Oberhofer, Martin, Kaestner, Lars, Weissgerber, Petra, Freichel, Marc, Flockerzi, Veit

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 39 KB

english, 2013

70

Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels

Tian, Jinbin, Thakur, Dhananjay P., Lu, Yungang, Zhu, Yingmin, Freichel, Marc, Flockerzi, Veit, Zhu, Michael X.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 16.73 MB

english, 2014

71

Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice

Uhl, Sebastian, Mathar, Ilka, Vennekens, Rudi, Freichel, Marc

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2014

Language:

english

File:

PDF, 2.79 MB

english, 2014

72

Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice

Weissmann, Norbert, Sydykov, Akylbek, Kalwa, Hermann, Storch, Ursula, Fuchs, Beate, Schnitzler, Michael Mederos y, Brandes, Ralf P., Grimminger, Friedrich, Meissner, Marcel, Freichel, Marc, Offermanns

Journal:

Nature Communications

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

73

Polyester Nanoparticles Presenting Mannose Residues: Toward the Development of New Vaccine Delivery Systems Combining Biodegradability and Targeting Properties

Rieger, Jutta, Freichels, Hélène, Imberty, Anne, Putaux, Jean-Luc, Delair, Thierry, Jérôme, Christine, Auzély-Velty, Rachel

Journal:

Biomacromolecules

Year:

2009

Language:

english

File:

PDF, 6.01 MB

english, 2009

74

Increase in cytosolic Ca 2+ produced by hypoxia and other depolarizing stimuli activates a non-selective cation channel in chemoreceptor cells of rat carotid body

Kang, Dawon, Wang, Jiaju, Hogan, James O., Vennekens, Rudi, Freichel, Marc, White, Carl, Kim, Donghee

Journal:

The Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 1.59 MB

english, 2014

75

Melanopsin signalling in mammalian iris and retina

Xue, T., Do, M. T. H., Riccio, A., Jiang, Z., Hsieh, J., Wang, H. C., Merbs, S. L., Welsbie, D. S., Yoshioka, T., Weissgerber, P., Stolz, S., Flockerzi, V., Freichel, M., Simon, M. I., Clapham, D. E.,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.99 MB

english, 2011

76

A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide

Michael Klaiber, Beatrice Dankworth, Martin Kruse, Michael Hartmann, Viacheslav O. Nikolaev, Ruey-Bing Yang, Katharina Völker, Birgit Gaßner, Heike Oberwinkler, Robert Feil, Marc Freichel, Klaus Grosc

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.57 MB

english, 2011

77

Moderate Calcium Channel Dysfunction in Adult Mice with Inducible Cardiomyocyte-specific Excision of the cacnb2 Gene

Meissner, M., Weissgerber, P., Londono, J. E. C., Prenen, J., Link, S., Ruppenthal, S., Molkentin, J. D., Lipp, P., Nilius, B., Freichel, M., Flockerzi, V.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.31 MB

english, 2011

78

Excision of Trpv6 Gene Leads to Severe Defects in Epididymal Ca2+ Absorption and Male Fertility Much Like Single D541A Pore Mutation

Weissgerber, P., Kriebs, U., Tsvilovskyy, V., Olausson, J., Kretz, O., Stoerger, C., Mannebach, S., Wissenbach, U., Vennekens, R., Middendorff, R., Flockerzi, V., Freichel, M.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 3.65 MB

english, 2012

79

NMDA Receptor-Dependent Synaptic Activation of TRPC Channels in Olfactory Bulb Granule Cells

Stroh, O., Freichel, M., Kretz, O., Birnbaumer, L., Hartmann, J., Egger, V.

Journal:

Journal of Neuroscience

Year:

2012

Language:

english

File:

PDF, 3.83 MB

english, 2012

80

Modulation of Ca2+ Signaling by Na+/Ca2+ Exchangers in Mast Cells

Aneiros, E., Philipp, S., Lis, A., Freichel, M., Cavalie, A.

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 1.08 MB

english, 2005

81

Heteromeric Canonical Transient Receptor Potential 1 and 4 Channels Play a Critical Role in Epileptiform Burst Firing and Seizure-Induced Neurodegeneration

Phelan, K. D., Mock, M. M., Kretz, O., Shwe, U. T., Kozhemyakin, M., Greenfield, L. J., Dietrich, A., Birnbaumer, L., Freichel, M., Flockerzi, V., Zheng, F.

Journal:

Molecular Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

82

Pain Perception in Mice Lacking the 3 Subunit of Voltage-activated Calcium Channels

Murakami, M., Fleischmann, B., De Felipe, C., Freichel, M., Trost, C., Ludwig, A., Wissenbach, U., Schwegler, H., Hofmann, F., Hescheler, J., Flockerzi, V., Cavalie, A.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 967 KB

english, 2002

83

Murine ORAI2 Splice Variants Form Functional Ca2+ Release-activated Ca2+ (CRAC) Channels

Gross, S. A., Wissenbach, U., Philipp, S. E., Freichel, M., Cavalie, A., Flockerzi, V.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 598 KB

english, 2007

84

Isoform-specific Inhibition of TRPC4 Channel by Phosphatidylinositol 4,5-Bisphosphate

Otsuguro, K.-i., Tang, J., Tang, Y., Xiao, R., Freichel, M., Tsvilovskyy, V., Ito, S., Flockerzi, V., Zhu, M. X., Zholos, A. V.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

85

The auxiliary subunit 1 of the skeletal muscle L-type Ca2+ channel is an endogenous Ca2+ antagonist

Andronache, Z., Ursu, D., Lehnert, S., Freichel, M., Flockerzi, V., Melzer, W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 978 KB

english, 2007

86

A Pathway Closely Related to the D-Tagatose Pathway of Gram-Negative Enterobacteria Identified in the Gram-Positive Bacterium Bacillus licheniformis

Van der Heiden, E., Delmarcelle, M., Lebrun, S., Freichels, R., Brans, A., Vastenavond, C. M., Galleni, M., Joris, B.

Journal:

Applied and Environmental Microbiology

Year:

2013

Language:

english

File:

PDF, 473 KB

english, 2013

87

Ca2+ Entry via TRPC Channels Is Necessary for Thrombin-induced NF- B Activation in Endothelial Cells through AMP-activated Protein Kinase and Protein Kinase C

Bair, A. M., Thippegowda, P. B., Freichel, M., Cheng, N., Ye, R. D., Vogel, S. M., Yu, Y., Flockerzi, V., Malik, A. B., Tiruppathi, C.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.16 MB

english, 2009

88

Enzymatic functionalization of a nanobody using protein insertion technology

Crasson, O., Rhazi, N., Jacquin, O., Freichels, A., Jerome, C., Ruth, N., Galleni, M., Filee, P., Vandevenne, M.

Journal:

Protein Engineering Design and Selection

Year:

2015

Language:

english

File:

PDF, 503 KB

english, 2015

89

Contribution of transient receptor potential channels to the control of GABA release from dendrites

Munsch, T., Freichel, M., Flockerzi, V., Pape, H.-C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 409 KB

english, 2003

90

The Guanine Nucleotide Exchange Factor p63RhoGEF, a Specific Link between Gq/11-coupled Receptor Signaling and RhoA

Lutz, S., Freichel-Blomquist, A., Yang, Y., Rumenapp, U., Jakobs, K. H., Schmidt, M., Wieland, T.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 782 KB

english, 2005

91

Mutations of Calcium Channel beta Subunit Genes in Mice

Freise, D., Himmerkus, N., Schroth, G., Trost, C., Weißgerber, P., Freichel, M., Flockerzi, V.

Journal:

Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 536 KB

english, 1999

92

The Ca2+ Sensor Stromal Interaction Molecule 1 (STIM1) Is Necessary and Sufficient for the Store-Operated Ca2+ Entry Function of Transient Receptor Potential Canonical (TRPC) 1 and 4 Channels in Endothelial Cells

Sundivakkam, P. C., Freichel, M., Singh, V., Yuan, J. P., Vogel, S. M., Flockerzi, V., Malik, A. B., Tiruppathi, C.

Journal:

Molecular Pharmacology

Year:

2012

Language:

english

File:

PDF, 5.71 MB

english, 2012

93

Male Fertility Depends on Ca2+ Absorption by TRPV6 in Epididymal Epithelia

Weissgerber, P., Kriebs, U., Tsvilovskyy, V., Olausson, J., Kretz, O., Stoerger, C., Vennekens, R., Wissenbach, U., Middendorff, R., Flockerzi, V., Freichel, M.

Journal:

Science Signaling

Year:

2011

Language:

english

File:

PDF, 1.77 MB

english, 2011

94

Critical role for the regulatory subunits of Cav channels in T lymphocyte function

Badou, A., Jha, M. K., Matza, D., Mehal, W. Z., Freichel, M., Flockerzi, V., Flavell, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 721 KB

english, 2006

95

A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide

Klaiber, M., Dankworth, B., Kruse, M., Hartmann, M., Nikolaev, V. O., Yang, R.-B., Volker, K., Gassner, B., Oberwinkler, H., Feil, R., Freichel, M., Groschner, K., Skryabin, B. V., Frantz, S., Birnbau

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 943 KB

english, 2011

96

Diversity and Developmental Expression of L-type Calcium Channel 2 Proteins and Their Influence on Calcium Current in Murine Heart

Link, S., Meissner, M., Held, B., Beck, A., Weissgerber, P., Freichel, M., Flockerzi, V.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.09 MB

english, 2009

97

Voltage Dependence of the Ca2+-activated Cation Channel TRPM4

Nilius, B., Prenen, J., Droogmans, G., Voets, T., Vennekens, R., Freichel, M., Wissenbach, U., Flockerzi, V.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 595 KB

english, 2003

98

The Role of TRP Proteins in Mast Cells

Freichel, Marc, Almering, Julia, Tsvilovskyy, Volodymyr

Journal:

Frontiers in Immunology

Year:

2012

Language:

english

File:

PDF, 421 KB

english, 2012

99

Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption

Woudenberg-Vrenken, T. E., Lameris, A. L., Weissgerber, P., Olausson, J., Flockerzi, V., Bindels, R. J. M., Freichel, M., Hoenderop, J. G. J.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2012

Language:

english

File:

PDF, 157 KB

english, 2012

100

Transient Receptor Potential Channels Function as a Coincidence Signal Detector Mediating Phosphatidylserine Exposure

Harper, M. T., Londono, J. E. C., Quick, K., Londono, J. C., Flockerzi, V., Philipp, S. E., Birnbaumer, L., Freichel, M., Poole, A. W.

Journal:

Science Signaling

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013