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51

Alternative complement pathway assessment in patients with atypical HUS

Lubka T. Roumenina, Chantal Loirat, Marie-Agnes Dragon-Durey, Lise Halbwachs-Mecarelli, Catherine Sautes-Fridman, Veronique Fremeaux-Bacchi

Journal:

Journal of Immunological Methods

Year:

2011

Language:

english

File:

PDF, 994 KB

english, 2011

52

Mutations in complement regulatory proteins predispose to preeclampsia

Jane E. Salmon, Michael Triebwasser, M. Kathryn Liszewski, David Kavanagh, Cara Heuser, Lubka Roumenina, Ware Branch, Tim Goodship, Veronique Fremeaux-Bacchi, John P. Atkinson

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

53

Fluid phase complement alternative pathway dysregulation: A major physiopathological mechanism in anti-FH autoantibodies-associated HUS

Caroline Blanc, Lubka Roumenina, Christophe Hue, Wolf Herman Fridman, Catherine Sautès-Fridman, Véronique Frémeaux-Bacchi, Marie-Agnès Dragon-Durey

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

54

Factor H protects stressed but not quiescent glomerular endothelial cells from complement-mediated damage

Lubka T. Roumenina, Marie Frimat, Caroline Poitou, Michal Malina, Sylvain Bigot, Marie-Agnès Dragon-Durey, Simon C. Satchell, Peter W. Mathieson, Lise Halbwachs-Mecarelli, Veronique Fremeaux-Bacchi

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

55

Analysis of genes coding for CD46, CD55 and C4b-binding protein in patients with idiopathic, recurrent, spontaneous pregnancy loss

Frida Bergström, Eric Mercier, Veronique Fremeaux-Bacchi, Jean-Christophe Gris, Anna M. Blom

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 81 KB

english, 2010

56

Functional characterization of mutations in complement C3 that predispose to aHUS

Elizabeth C. Miller, Lubka Roumenina, Veronique Fremeaux-Bacchi, John P. Atkinson

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

57

Acquired and hereditary complement abnormalities in atypical hemolytic and uremic syndrome and membranoproliferative glomerulonephritis

Veronique Fremeaux-Bacchi, Lubka T. Roumenina, Aude Servais, Marie-Agnes Dragon-Durey, Chantal Loirat

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 77 KB

english, 2010

58

Complement factor I in health and disease

Sara C. Nilsson, Robert B. Sim, Susan M. Lea, Veronique Fremeaux-Bacchi, Anna M. Blom

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 640 KB

english, 2011

59

A novel mutation in the C3 gene and recurrent invasive pneumococcal infection: A clue for vaccine development

Michael Goldberg, Véronique Fremeaux-Bacchi, Penina Koch, Zvi Fishelson, Yitzhak Katz

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 761 KB

english, 2011

60

High prevalence of hybrid genes involving CFH and CFHR1 in atypical Hemolytic Uremic Syndrome

V. Fremeaux-Bacchi, L. Strain, D. Beury, S. Ngo, L. Roumenina, M.A. Dragon-Durey, K. Marchbank, L. Holmes, T.H.J. Goodship

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 335 KB

english, 2011

61

Genetic variants in CFH and CD46 are the major susceptibility factors for aHUS—An association study of multiple complement genes

L. Ermini, T. Goodship, L. Strain, M. Weale, S. Sacks, H. Cordell, V. Frémeaux-Bacchi, N. Sheerin

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

62

Structure-Function-Disease map for the genetic abnormalities in the central complement component C3

L.T. Roumenina, L. Halbwachs-Mecarelli, P. Bordereau, T. Rybkine, M.A. Dragon-Durey, M. Noris, C. Sautes-Fridman, V. Frémeaux-Bacchi

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

63

Heme interacts with C1Q and inhibits the classical complement pathway

L.T. Roumenina, M. Radanova, B. Atanasov, K. Popov, S. Kaveri, S. Lacroix-Desmazes, V. Frémeaux-Bacchi, J. Dimitrov

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

64

Anti-factor H auto-antibodies in C3 glomerulopathy

M.A. Dragon-Durey, C. Blanc, L. Roumenina, S. Chauvet, Y. Ashraf, B. Moulin, P. Le Pogamp, V. Fremeaux-Bacchi, W.H. Fridman

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

65

Extended role for antibodies anti-Factor H in alternative pathway dysregulation in a context of atypical hemolytic uremic syndrome (aHUS)

C. Blanc, L. Roumenina, Y. Ashraf, W. Fridman, C. Sautès-Fridman, V. Frémeaux-Bacchi, M. Dragon-Durey

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

66

Molecular characterization and clinical history of a homozygous functional C1q abnormality

L.T. Roumenina, D. Sène, M. Radanova, J. Blouin, L. Halbwachs-Mecarelli, M.A. Dragon-Durey, W. Fridman, V. Frémeaux-Bacchi

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

67

Factor H and MCP haplotypes don’t confer susceptibility for C3 glomerulopathy

M. Lequintrec, A. Servais, S. Ngo, M.A. Dragon-Durey, L. Roumenina, V. Fremeaux-Bacchi

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

68

Three novel C3 mutations in atypical haemolytic uraemic syndrome: Two ways to hyperactive C3 convertase

M.M. Malina, R.L. Roumenina, B.P. Bordereau, S.C.P. Schmitt, M.A.M. Majid, J.A. Jankauskiene, S.T. Seeman, H.-M.L. Halbwachs-Mecarelli, F.-B.V. Fremeaux-Bacchi, S.F. Schaefer

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 71 KB

english, 2011

69

Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS

Luca Ermini, Timothy H.J. Goodship, Lisa Strain, Michael E. Weale, Steven H. Sacks, Heather J. Cordell, Veronique Fremeaux-Bacchi, Neil S. Sheerin

Journal:

Molecular Immunology

Year:

2012

Language:

english

File:

PDF, 783 KB

english, 2012

70

Late-onset thrombocytic microangiopathy caused by cblC disease: Association with a factor H mutation

Vincent Guigonis, Véronique Frémeaux-Bacchi, Stéphane Giraudier, Rémi Favier, Didier Borderie, Ziad Massy, Béatrice Mougenot, David S. Rosenblatt, Georges Deschênes

Journal:

American Journal of Kidney Diseases

Year:

2005

Language:

english

File:

PDF, 442 KB

english, 2005

71

Unusual Clinical Severity of Complement Membrane Cofactor Protein–Associated Hemolytic-Uremic Syndrome and Uniparental Isodisomy

Veronique Fremeaux-Bacchi, Damien Sanlaville, Soraya Menouer, Jacques Blouin, Marie-Agnès Dragon-Durey, Michel Fischbach, Michel Vekemans, Wolf Herman Fridman

Journal:

American Journal of Kidney Diseases

Year:

2007

Language:

english

File:

PDF, 880 KB

english, 2007

72

Complement Factor H Deficiency and Posttransplantation Glomerulonephritis With Isolated C3 Deposits

Olivia Boyer, Laure-Hélène Noël, Eve Balzamo, Geneviève Guest, Nathalie Biebuyck, Marina Charbit, Rémi Salomon, Véronique Frémeaux-Bacchi, Patrick Niaudet

Journal:

American Journal of Kidney Diseases

Year:

2008

Language:

english

File:

PDF, 805 KB

english, 2008

73

Inherited Deficiency of Membrane Cofactor Protein Expression and Varying Manifestations of Recurrent Atypical Hemolytic Uremic Syndrome in a Sibling Pair

Lionel Couzi, Cécile Contin-Bordes, Florence Marliot, Anne Sarrat, Pierre Grimal, Jean-François Moreau, Pierre Merville, Véronique Fremeaux-Bacchi

Journal:

American Journal of Kidney Diseases

Year:

2008

Language:

english

File:

PDF, 549 KB

english, 2008

74

Pulse Cyclophosphamide Therapy and Clinical Remission in Atypical Hemolytic Uremic Syndrome With Anti–Complement Factor H Autoantibodies

Olivia Boyer, Eve Balzamo, Marina Charbit, Nathalie Biebuyck-Gougé, Rémi Salomon, Marie-Agnès Dragon-Durey, Véronique Frémeaux-Bacchi, Patrick Niaudet

Journal:

American Journal of Kidney Diseases

Year:

2010

Language:

english

File:

PDF, 371 KB

english, 2010

75

Acute Presentation and Persistent Glomerulonephritis Following Streptococcal Infection in a Patient With Heterozygous Complement Factor H–Related Protein 5 Deficiency

Katherine A. Vernon, Elena Goicoechea de Jorge, Angela E. Hall, Veronique Fremeaux-Bacchi, Timothy J. Aitman, H. Terence Cook, Robert Hangartner, Ania Koziell, Matthew C. Pickering

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 993 KB

english, 2012

76

Recurrence of HUS Due to CD46/MCP Mutation After Renal Transplantation: A Role for Endothelial Microchimerism

V. Frémeaux-Bacchi, N. Arzouk, S. Ferlicot, B. Charpentier, R. Snanoudj, A. Dürrbach

Journal:

American Journal of Transplantation

Year:

2007

Language:

english

File:

PDF, 11.91 MB

english, 2007

77

Complement Mutation-Associated De Novo Thrombotic Microangiopathy Following Kidney Transplantation

M. Le Quintrec, A. Lionet, N. Kamar, A. Karras, S. Barbier, M. Buchler, F. Fakhouri, F. Provost, W. H. Fridman, E. Thervet, C. Legendre, J. Zuber, V. Frémeaux-Bacchi

Journal:

American Journal of Transplantation

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

78

Anti-Factor H Autoantibodies in a Fifth Renal Transplant Recipient with Atypical Hemolytic and Uremic Syndrome

M. Le Quintrec, J. Zuber, L.-H. Noel, E. Thervet, V. Frémeaux-Bacchi, W.-H. Fridman, C. Legendre, M.-A. Dragon-Durey

Journal:

American Journal of Transplantation

Year:

2009

Language:

english

File:

PDF, 296 KB

english, 2009

79

Safety and Long-Term Efficacy of Eculizumab in a Renal Transplant Patient with Recurrent Atypical Hemolytic–Uremic Syndrome

V. Chatelet, V. Frémeaux-Bacchi, T. Lobbedez, M. Ficheux, B. Hurault de Ligny

Journal:

American Journal of Transplantation

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

80

Renal Transplantation Under Prophylactic Eculizumab in Atypical Hemolytic Uremic Syndrome With CFH/CFHR1 Hybrid Protein

S. Krid, LT. Roumenina, D. Beury, M. Charbit, O. Boyer, V. Frémeaux-Bacchi, P. Niaudet

Journal:

American Journal of Transplantation

Year:

2012

Language:

english

File:

PDF, 682 KB

english, 2012

81

Assessment of complement activation in clinical samples comparison of immunochemical and functional measurements of complement components with quantitation of activation fragments

F. Maillet, V. Frémeaux-Bacchi, B. Uhring-Lambert, M.D. Kazatchkine

Journal:

Journal of Immunological Methods

Year:

1992

Language:

english

File:

PDF, 543 KB

english, 1992

82

Génétique du déficit en C1 inhibiteur

V. Frémeaux-Bacchi

Journal:

Revue Française d'Allergologie et d'Immunologie Clinique

Year:

2008

Language:

french

File:

PDF, 106 KB

french, 2008

83

Déficit homozygote en facteur I du complément révélé par une infection systémique répétée à Streptococcus pneumoniae

M. Monfort-Gouraud, C. Vignon, A. Vincens, J. Blouin, V. Frémeaux-Bacchi, P. Talon

Journal:

Archives de Pédiatrie

Year:

2006

Language:

french

File:

PDF, 137 KB

french, 2006

84

Syndrome hémolytique et urémique au décours d’une infection materno-fœtale à Escherichia coli K1

M. Flandrois, A. Bessière, S. Vieira-Roth, M. Vergnaud, V. Frémeaux-Bacchi, P. Eckart

Journal:

Archives de Pédiatrie

Year:

2011

File:

PDF, 186 KB

2011

85

Genetics of hemolytic uremic syndromes

Michal Malina, Lubka T. Roumenina, Tomáš Seeman, Moglie Le Quintrec, Marie-Agnes Dragon-Durey, Franz Schaefer, Véronique Fremeaux-Bacchi

Journal:

La Presse Médicale

Year:

2012

Language:

english

File:

PDF, 745 KB

english, 2012

86

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome

Anna Richards, M. Kathryn Liszewski, David Kavanagh, Celia J. Fang, Elizabeth Moulton, Veronique Fremeaux-Bacchi, Giuseppe Remuzzi, Marina Noris, Timothy H.J. Goodship, John P. Atkinson

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 441 KB

english, 2007

87

Protective or aggressive: Paradoxical role of C3 in atypical hemolytic uremic syndrome

Véronique Fremeaux-Bacchi, Catherine Regnier, Jacques Blouin, Marie-Agnès Dragon-Durey, Wolf Herman Fridman, Bert Janssen, Chantal Loirat

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 77 KB

english, 2007

88

A mutation in factor I that is strongly associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

Sara C. Nilsson, Diana Karpman, Fariba Vaziri-Sani, Ann-Charlotte Kristoffersson, Rémi Salomon, Francois Provot, Veronique Fremeaux-Bacchi, Leendert A. Trouw, Anna M. Blom

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 73 KB

english, 2007

89

A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

Sara C. Nilsson, Diana Karpman, Fariba Vaziri-Sani, Ann-Charlotte Kristoffersson, Rémi Salomon, Francois Provot, Veronique Fremeaux-Bacchi, Leendert A. Trouw, Anna M. Blom

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 476 KB

english, 2007

90

Where next with atypical hemolytic uremic syndrome?

T. Sakari Jokiranta, Peter F. Zipfel, Veronique Fremeaux-Bacchi, C. Mark Taylor, Timothy J.H. Goodship, Marina Noris

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 425 KB

english, 2007

91

A role for complement (CD46)-activated T cells in generating optimal B cell responses

Anja Fuchs, Veronique Fremeaux-Bacchi, Claudia Kemper

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 98 KB

english, 2007

92

Mutations in complement C3 predispose to development of atypical haemolytic uraemic syndrome

V. Fremeaux-Bacchi, T. Goodship, C.H. Regnier, M.A. Dragon-Durey, B. Janssen, J. Atkinson

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

93

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome

David Kavanagh, Anna Richards, Marina Noris, Richard Hauhart, M. Kathryn Liszewski, Diana Karpman, Judith A. Goodship, Veronique Fremeaux-Bacchi, Giuseppe Remuzzi, Timothy H.J. Goodship, John P. Atkin

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 914 KB

english, 2008

94

Development of anti-factor H auto-antibodies genetically predisposed in atypical HUS

Marie-Agnès Dragon-Durey, Chantal Loirat, Bruno Ranchin, Miriam Davidovits, Nobuaki Takagi, Jacques Blouin, Wolf Herman Fridman, Véronique Frémeaux-Bacchi

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 52 KB

english, 2007

95

Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis and the HELLP syndrome

Celia J. Fang, Veronique Fremeaux-Bacchi, M. Kathryn Liszewski, Gaia Pianetti, Marina Noris, Timothy H.J. Goodship, John P. Atkinson

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

96

A non-synonymous polymorphism (arg240his) in C4b-binding protein is associated with atypical haemolytic uraemic syndrome and leads to impaired alternative pathway cofactor activity

D. Kavanagh, F. Bergstrom, A. Blom, M. Edey, M. Diaz-Torres, L. Strain, J. Goodship, A. Lampe, V. Fremeaux-Bacchi, T. Goodship

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 66 KB

english, 2007

97

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome

David Kavanagh, Anna Richards, Marina Noris, Richard Hauhart, M. Kathryn Liszewski, Diana Karpman, Judith A. Goodship, Veronique Fremeaux-Bacchi, Giuseppe Remuzzi, Timothy H.J. Goodship, John P. Atkin

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 56 KB

english, 2007

98

Heterogeneous histological pattern of membranoproliferative glomerulonephritis associated with alternative pathway abnormalities in human

Aude Servais, Laure-Hélène Noël, Marie-Agnès Dragon-Durey, Fadi Fakhouri, Jacques Blouin, Marie-Claire Gübler, Philippe Lesavre, Chantal Loirat, Jean Pierre Grunfeld, Véronique Frémeaux-Bacchi

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

99

Is CFHR1 deletion a susceptibility factor for atypical haemolytic uraemic syndrome by itself?

Marie-Agnes Dragon-Durey, Chantal Loirat, Florence Marliot, Wolf Herman Fridman, Veronique Fremeaux-Bacchi

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

100

Molecular and functional analysis of complement factor I mutations in atypical haemolytic uraemic syndrome patients

Sara C. Nilsson, Leendert A. Trouw, Bruno O. Villoutreix, Veronique Fremeaux-Bacchi, Anna M. Blom

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

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