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51

Structure–Activity Relationship Studies of Orally Active Antimalarial 3,5-Substituted 2-Aminopyridines

González Cabrera, Diego, Douelle, Frederic, Younis, Yassir, Feng, Tzu-Shean, Le Manach, Claire, Nchinda, Aloysius T., Street, Leslie J., Scheurer, Christian, Kamber, Jolanda, White, Karen L., Montagna

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 807 KB

english, 2012

52

Admission risk factors for cerebral vasospasm in ruptured brain arteriovenous malformations: An observational study

Vibol Chhor, Yannick Le Manach, Fréderic Clarençon, Aurélien Nouet, Jean-Louis Daban, Lamine Abdennour, Louis Puybasset, Thomas Lescot

Journal:

Critical Care (BioMed Central)

Year:

2011

Language:

english

File:

PDF, 422 KB

english, 2011

53

Evaluation of a novel closed-loop fluid-administration system based on dynamic predictors of fluid responsiveness: anin silicosimulation study

Joseph Rinehart, Brenton Alexander, Yannick Le Manach, Christoph Hofer, Benoit Tavernier, Zeev N Kain, Maxime Cannesson

Journal:

Critical Care (BioMed Central)

Year:

2011

Language:

english

File:

PDF, 621 KB

english, 2011

54

The motor component does not convey all the mortality prediction capacity of the Glasgow Coma Scale in trauma patients

Benoît Vivien, Jean-Michel Yeguiayan, Yannick Le Manach, Claire Bonithon-Kopp, Sébastien Mirek, Delphine Garrigue, Marc Freysz, Bruno Riou

Journal:

The American Journal of Emergency Medicine

Year:

2012

Language:

english

File:

PDF, 760 KB

english, 2012

55

Statins: A new pharmacological agent for free flap surgery?

Guillaume Karsenti, Yannick Le Manach, Stéphanie Bouvier, André Chaine, Chloé Bertolus

Journal:

Journal of Plastic, Reconstructive & Aesthetic Surgery

Year:

2010

Language:

english

File:

PDF, 117 KB

english, 2010

56

China's distant-water fisheries in the 21st century

Pauly, Daniel, Belhabib, Dyhia, Blomeyer, Roland, Cheung, William W W L, Cisneros-Montemayor, Andrés M, Copeland, Duncan, Harper, Sarah, Lam, Vicky W Y, Mai, Yining, Le Manach, Frédéric, Österblom, He

Journal:

Fish and Fisheries

Year:

2014

Language:

english

File:

PDF, 469 KB

english, 2014

57

Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum

Le Manach, Claire, Scheurer, Christian, Sax, Sibylle, Schleiferböck, Sarah, Cabrera, Diego, Younis, Yassir, Paquet, Tanya, Street, Leslie, Smith, Peter, Ding, Xavier C, Waterson, David, Witty, Michael

Journal:

Malaria Journal

Year:

2013

Language:

english

File:

PDF, 277 KB

english, 2013

58

Exploring Patterns of Seafood Provision Revealed in the Global Ocean Health Index

Kleisner, Kristin M., Longo, Catherine, Coll, Marta, Halpern, Ben S., Hardy, Darren, Katona, Steven K., Le Manach, Frédéric, Pauly, Daniel, Rosenberg, Andrew A., Samhouri, Jameal F., Scarborough, Cour

Journal:

AMBIO: A Journal of the Human Environment

Year:

2013

Language:

english

File:

PDF, 2.37 MB

english, 2013

59

First closed-loop goal directed fluid therapy during surgery: A pilot study

Rinehart, J., Le Manach, Y., Douiri, H., Lee, C., Lilot, M., Le, K., Canales, C., Cannesson, M.

Journal:

Annales Françaises d'Anesthésie et de Réanimation

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

60

Impact du rapport de la fréquence cardiaque sur la fréquence respiratoire sur la valeur prédictive de la variation respiratoire de la pression pulsée

Tashk, P., Alexander, B.-S., Hofer, C.-K., Tavernier, B., Goarin, J.-P., Cannesson, M., Le Manach, Y.

Journal:

Annales Françaises d'Anesthésie et de Réanimation

Year:

2013

File:

PDF, 333 KB

2013

61

The impact of postoperative discontinuation or continuation of chronic statin therapy on cardiac outcome after major vascular surgery

Le Manach, Y., Godet, G., Coriat, P.

Journal:

Journal of Vascular Surgery

Year:

2007

Language:

english

File:

PDF, 36 KB

english, 2007

62

P35 - Le système français d’alerte canicule et santé (SACS) : mise en place et évolution

Laaidi, K., Pascal, M., Ledrans, M., Le tertre, A., Medina, S., Salines, G., Bessemoulin, P., Manach, J., Strauss, B., Cohen, J.C., Empereur-Bissonnet, P.

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2005

Language:

french

File:

PDF, 44 KB

french, 2005

63

UNIVERSITY OF LONDON.

Laaidi, K., Pascal, M., Ledrans, M., Le tertre, A., Medina, S., Salines, G., Bessemoulin, P., Manach, J., Strauss, B., Cohen, J.C., Empereur-Bissonnet, P.

Journal:

Year:

1860

Language:

english

File:

PDF, 166 KB

english, 1860

64

The Prognostic Value of Pre-Operative and Post-Operative B-Type Natriuretic Peptides in Patients Undergoing Noncardiac Surgery

Rodseth, Reitze N., Biccard, Bruce M., Le Manach, Yannick, Sessler, Daniel I., Lurati Buse, Giovana A., Thabane, Lehana, Schutt, Robert C., Bolliger, Daniel, Cagini, Lucio, Cardinale, Daniela, Chong,

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 710 KB

english, 2014

65

Variations de la courbe de pléthysmographie de la saturation périphérique en oxygène causées par le lever de jambe passif chez des patients en respiration spontanée

Delerme, S., Lvovschi, V., Renault, R., Arhan, A., Le Manach, Y., Riou, B., Ray, P.

Journal:

Journal Européen des Urgences

Year:

2007

Language:

french

File:

PDF, 74 KB

french, 2007

66

Traitement de la pseudo-occlusion colique aiguë (syndrome d'Ogilvie) par le cisapride

Baechle, J.P., Le Manach, Y., Pitti, R., Tordjmann, T.

Journal:

Annales Françaises d'Anesthésie et de Réanimation

Year:

1994

File:

PDF, 274 KB

1994

67

Élévation de la troponine sérique au cours du coup de chaleur environnemental

Chopin, S., Hausfater, P., Le Manach, Y., Santin, A., Dautheville, S., Patzak, A., Hericord, P., Riou, B.

Journal:

Journal Européen des Urgences

Year:

2009

Language:

french

File:

PDF, 65 KB

french, 2009

68

Elevation of cardiac troponin I during non-exertional heat-related illnesses in the context of a heatwave

Pierre Hausfater,Benoît Doumenc,Sébastien Chopin,Yannick Le Manach…

Journal:

Critical Care (BioMed Central)

Year:

2010

Language:

english

File:

PDF, 715 KB

english, 2010

69

2,4-Diaminothienopyrimidines as Orally Active Antimalarial Agents

González Cabrera, Diego, Le Manach, Claire, Douelle, Frederic, Younis, Yassir, Feng, Tzu-Shean, Paquet, Tanya, Nchinda, Aloysius T., Street, Leslie J., Taylor, Dale, de Kock, Carmen, Wiesner, Lubbe, D

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.06 MB

english, 2014

70

Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 1

Le Manach, Claire, Gonzàlez Cabrera, Diego, Douelle, Frederic, Nchinda, Aloysius T., Younis, Yassir, Taylor, Dale, Wiesner, Lubbe, White, Karen L., Ryan, Eileen, March, Corinne, Duffy, Sandra, Avery,

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

71

Effets des statines à forte dose sur la fonction rénale après chirurgie aortique imposant un clampage sus rénal

Dolla, E., Gaillard, J., Le Manach, Y., Khelifa, I., Fléron, M.H., Coriat, P.

Journal:

Annales Françaises d'Anesthésie et de Réanimation

Year:

2014

Language:

french

File:

PDF, 125 KB

french, 2014

72

Intérêt de la troponie UltraSensible préopératoire pour le diagnostic de lésion myocardique aiguë postopératoire

El Gharbi, F., Gaillard, J., Le Manach, Y., Guezennec, J., Munck, C., Khelifa, I., Borel, M., Fléron, M.H., Goarin, J.P., Coriat, P.

Journal:

Annales Françaises d'Anesthésie et de Réanimation

Year:

2014

Language:

french

File:

PDF, 220 KB

french, 2014

73

Une prise en charge gériatrique précoce améliore le pronostic de patients âgés admis en urgence pour une fracture du col du fémur

Cohen-Bittan, J., Raux, M., Khiami, F., Le Manach, Y., Mézière, A., Verny, M., Riou, B., Boddaert, J.

Journal:

La Revue de Médecine Interne

Year:

2014

Language:

french

File:

PDF, 63 KB

french, 2014

74

Analytical comparison of the new point-of-care troponin T immunoassay on AQT90Flex® analyzer (Radiometer) and the high-sensitivity troponin T immunoassay on ModularE170® (Roche Diagnostics)

Monneret, Denis, Abbes, Rachel Ahmed Ben, Omarjee, Riyadh, Devilliers, Catherine, Le Manach, Yannick, Raux, Mathieu, Coriat, Pierre, Imbert-Bismut, Françoise, Bonnefont-Rousselot, Dominique

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2014

Language:

english

File:

PDF, 588 KB

english, 2014

75

Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 2

Le Manach, Claire, Paquet, Tanya, Gonzàlez Cabrera, Diego, Younis, Yassir, Taylor, Dale, Wiesner, Lubbe, Lawrence, Nina, Schwager, Sylva, Waterson, David, Witty, Michael J., Wittlin, Sergio, Street, L

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 589 KB

english, 2014

76

Computed Tomography-Estimated Specific Gravity at Hospital Admission Predicts 6-Month Outcome in Mild-to-Moderate Traumatic Brain Injury Patients Admitted to the Intensive Care Unit

Degos, Vincent, Lescot, Thomas, Icke, Christian, Le Manach, Yannick, Fero, Katherin, Sanchez, Paola, Hadiji, Bassem, Zouaoui, Abederrezak, Boch, Anne-Laure, Abdennour, Laine, Apfel, Christian C., Puyb

Journal:

Survey of Anesthesiology

Year:

2012

Language:

english

File:

PDF, 210 KB

english, 2012

77

The Long-Term Impact of Early Cardiovascular Therapy Intensification for Postoperative Troponin Elevation After Major Vascular Surgery

Foucrier, Arnaud, Rodseth, Reitze, Aissaoui, Mohamed, Ibanes, Cristina, Goarin, Jean-Pierre, Landais, Paul, Coriat, Pierre, Le Manach, Yannick

Journal:

Anesthesia & Analgesia

Year:

2014

Language:

english

File:

PDF, 689 KB

english, 2014

78

Drug-eluting stent thrombosis in patients undergoing non-cardiac surgery: is it always a problem?

Godet, G., Le Manach, Y., Lesache, F., Perbet, S., Coriat, P.

Journal:

BJA British Journal of Anaesthesia

Year:

2008

Language:

english

File:

PDF, 86 KB

english, 2008

79

Continuous versus Intermittent Infusions of Ceftazidime for Treating Exacerbation of Cystic Fibrosis

Hubert, D., Le Roux, E., Lavrut, T., Wallaert, B., Scheid, P., Manach, D., Grenet, D., Sermet-Gaudelus, I., Ramel, S., Cracowski, C., Sardet, A., Wizla, N., Deneuville, E., Garraffo, R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 269 KB

english, 2009

80

Central venous saturation is not an alternative to mixed venous saturation during cardiopulmonary bypass in coronary artery surgery patients

Soussi, M., Jebali, M., Le Manach, Y., Nasri, M., Zouari, B., Chenik, S., Ferjani, M.

Journal:

Year:

2012

Language:

english

File:

PDF, 638 KB

english, 2012

81

AIP Conference Proceedings [AIP INTERNATIONAL CONFERENCE ON ADVANCES IN MATERIALS AND PROCESSING TECHNOLOGIES (AMPT2010) - Paris, (France) (24–27 October 2010)] - Surface defects on thin sheets after flanging

Le Port, Alban, Thuillier, Sandrine, Manach, Pierre-Yves, Chinesta, Francisco, Chastel, Yvan, El Mansori, Mohamed

Year:

2011

Language:

english

File:

PDF, 423 KB

english, 2011

82

AIP Conference Proceedings [AIP THE 8TH INTERNATIONAL CONFERENCE AND WORKSHOP ON NUMERICAL SIMULATION OF 3D SHEET METAL FORMING PROCESSES (NUMISHEET 2011) - Seoul, (Republic of Korea) (21–26 August 2011)] - Surface Defects in Sheet Metal Forming: a Simulative Laboratory Device and Comparison with FE Analysis

Thuillier, Sandrine, Le Port, Alban, Manach, Pierre-Yves

Year:

2011

Language:

english

File:

PDF, 3.57 MB

english, 2011

83

Structure Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines.

Gonzalez Cabrera, Diego, Douelle, Frederic, Le Manach, Claire, Han, Ze, Paquet, Tanya, Taylor, Dale, Njoroge, Mathew, Lawrence, Nina, Wiesner, Lubbe, Waterson, David, Witty, Michael J., Wittlin, Sergi

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 781 KB

english, 2015

84

Flawed validation of FRAX

Collins, Gary S., Le Manach, Yannick

Journal:

Year:

2015

Language:

english

File:

PDF, 164 KB

english, 2015

85

Outcomes After Hip Fracture Surgery Compared With Elective Total Hip Replacement

Le Manach, Yannick, Collins, Gary, Bhandari, Mohit, Bessissow, Amal, Boddaert, Jacques, Khiami, Frédéric, Chaudhry, Harman, De Beer, Justin, Riou, Bruno, Landais, Paul, Winemaker, Mitchell, Boudemaghe

Journal:

JAMA The Journal of the American Medical Association

Year:

2015

Language:

english

File:

PDF, 287 KB

english, 2015

86

Association between pre-operative statin use and major cardiovascular complications among patients undergoing non-cardiac surgery: the VISION study

O. Berwanger, Y. Le Manach, E. A. Suzumura, B. Biccard, S. K. Srinathan, W. Szczeklik, J. A. Espirito Santo, E. Santucci, A. B. Cavalcanti, R. A. Archbold, P. J. Devereaux

Year:

2015

Language:

english

File:

PDF, 549 KB

english, 2015

87

A novel pyrazolopyridine with in vivo activity in Plasmodium berghei and Plasmodium falciparum-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyridazines.

Le Manach, Claire, Paquet, Tanya, Brunschwig, Christel, Njoroge, Mathew, Han, Ze, Gonzalez Cabrera, Diego, Bashyam, Sridevi, Dhinakaran, Rajkumar, Taylor, Dale, Reader, Janette, Botha, Mariette, Churc

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 633 KB

english, 2015

88

Disagreement between cardiac output measurement devices: which device is the gold standard?: Fig 1

Le Manach, Y., Collins, G. S.

Journal:

British Journal of Anaesthesia

Year:

2015

Language:

english

File:

PDF, 124 KB

english, 2015

89

Effect of two TiO 2 nanoparticles on the growth of unicellular green algae using the OECD 201 test guideline: influence of the exposure system

Nicolas, Manier, Séverine, Le Manach, Anne, Bado-Nilles, Pascal, Pandard

Journal:

Toxicological & Environmental Chemistry

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

90

Drug-eluting stent thrombosis in patients undergoing non-cardiac surgery

Ramakrishna, H., Godet, G., Le Manach, Y., Lesache, F., Perbet, S., Coriat, P.

Journal:

BJA British Journal of Anaesthesia

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

91

Impact of aspirin with or without clopidogrel on postoperative bleeding and blood transfusion in coronary surgical patients treated prophylactically with a low-dose of aprotinin

Ouattara, A., Bouzguenda, H., Le Manach, Y., Leger, P., Mercadier, A., Leprince, P., Bonnet, N., Montalescot, G., Riou, B., Coriat, P.

Journal:

European Heart Journal

Year:

2007

Language:

english

File:

PDF, 427 KB

english, 2007

92

Small data sets to develop and validate prognostic models are problematic

Collins, Gary S., Le Manach, Yannick

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 207 KB

english, 2016

93

Hip Fracture Surgery vs Elective Total Hip Replacement—Reply

Le Manach, Yannick, Collins, Gary S., Devereaux, P. J.

Journal:

JAMA The Journal of the American Medical Association

Year:

2016

Language:

english

File:

PDF, 79 KB

english, 2016

94

Postoperative risk of patients with previous coronary stenting undergoing a non cardiac surgery

Le Saché, F., Perbet, S., Le Manach, Y., Godet, G.

Journal:

European Journal of Anaesthesiology

Year:

2007

Language:

english

File:

PDF, 43 KB

english, 2007

95

Complications of Percutaneous Tracheostomy

Briche, Thierry, Le Manach, Yvon, Pats, Bruno

Journal:

Year:

2001

Language:

english

File:

PDF, 61 KB

english, 2001

96

Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetics

Lecomte, P., Ouattara, A., Le Manach, Y., Mabrouk, N., Landi, M., Riou, B., Coriat, P.

Journal:

European Journal of Anaesthesiology

Year:

2005

Language:

english

File:

PDF, 45 KB

english, 2005

97

What Do Prehospital Trauma Scores Predict Besides Mortality?

Raux, Mathieu, Sartorius, Danielle, Le Manach, Yannick, David, Jean-Stéphane, Riou, Bruno, Vivien, Benoît

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

2011

File:

PDF, 424 KB

2011

98

Postoperative statin withdrawal is associated with increased cardiac morbidity

Le Manach, Y., Godet, G., Goarin, J P., Fleron, M H., Coriat, P.

Journal:

European Journal of Anaesthesiology

Year:

2007

Language:

english

File:

PDF, 43 KB

english, 2007

99

Comparing treatment effects between propensity scores and randomized controlled trials: improving conduct and reporting

Collins, G. S., Le Manach, Y.

Journal:

European Heart Journal

Year:

2012

Language:

english

File:

PDF, 101 KB

english, 2012

100

Low cardiac troponin I elevations predict in hospital mortality after major vascular surgery

Le Manach, Y., Godet, G., Bertrand, M., Fléron, M. H., Goarin, J. P., Coriat, P.

Journal:

European Journal of Anaesthesiology

Year:

2005

Language:

english

File:

PDF, 44 KB

english, 2005