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51

Acquired bleeding model induced by dilutional coagulopathy in the rabbit

I Pragst,B Doerr,F Kaspereit,W Krege,E Raquet,G Dickneite

Journal:

Critical Care (BioMed Central)

Year:

2009

Language:

english

File:

PDF, 15.50 MB

english, 2009

52

Treatment of the coagulation deficit during extracorporeal circulation in a porcine model by a prothrombin complex concentrate

F Kaspereit,S Hoffman,I Pragst,G Dickneite

Journal:

Critical Care (BioMed Central)

Year:

2010

Language:

english

File:

PDF, 18.56 MB

english, 2010

53

Analysis of the safety and pharmacodynamics of human fibrinogen concentrate in animals

Beyerle, Andrea, Nolte, Marc W., Solomon, Cristina, Herzog, Eva, Dickneite, Gerhard

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 820 KB

english, 2014

54

Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model

Herzog, Eva, Kaspereit, Franz J., Krege, Wilfried, Doerr, Baerbel, van Ryn, Joanne, Dickneite, Gerhard, Pragst, Ingo

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 541 KB

english, 2014

55

Pharmacological characteristics of a novel, recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP)

Zollner, S., Schuermann, D., Raquet, E., Mueller-Cohrs, J., Weimer, T., Pragst, I., Dickneite, G., Schulte, S.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 234 KB

english, 2014

56

Reduction of r-hirudin induced bleeding in pigs by the administration of von Willebrand factor

Dickneite, G., Friesen, H.-J., Kumpe, G., Reers, M.

Journal:

Year:

1996

Language:

english

File:

PDF, 810 KB

english, 1996

57

Synthesis and Characterisation of Novel Thrombin Inhibitors Based on 4-Amidinophenylalanine

Reers, Martin, Koschinsky, Miner, Dickneite, Gerhard, Hoffmann, Dieter, Czech, JÖ, Stür, Werner

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 628 KB

english, 1995

58

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

Hagedorn, I., Schmidbauer, S., Pleines, I., Kleinschnitz, C., Kronthaler, U., Stoll, G., Dickneite, G., Nieswandt, B.

Journal:

Year:

2010

Language:

english

File:

PDF, 576 KB

english, 2010

59

Combined treatment with C1 esterase inhibitor and antithrombin III improves survival in severe acute experimental pancreatitis.

Yamaguchi, H, Weidenbach, H, Luhrs, H, Lerch, M M, Dickneite, G, Adler, G

Journal:

Year:

1997

Language:

english

File:

PDF, 1.31 MB

english, 1997

60

A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk

Larsson, M., Rayzman, V., Nolte, M. W., Nickel, K. F., Bjorkqvist, J., Jamsa, A., Hardy, M. P., Fries, M., Schmidbauer, S., Hedenqvist, P., Broome, M., Pragst, I., Dickneite, G., Wilson, M. J., Nash,

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

61

Prevention of Gynaecological Adhesions using Haemostatic Fleece in a Rabbit Model

Dickneite, G., Rolle, U., Rosenthal, D.

Journal:

Journal of International Medical Research

Year:

2006

Language:

english

File:

PDF, 1.74 MB

english, 2006

62

Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model

Dickneite, G., Pragst, I.

Journal:

BJA British Journal of Anaesthesia

Year:

2009

Language:

english

File:

PDF, 196 KB

english, 2009

63

C1-esterase inhibitor treatment: preclinical safety aspects on the potential prothrombotic risk

Schürmann, D., Herzog, E., Raquet, E., Nolte, M. W., May, F., Müller-Cohrs, J., Björkqvist, J., Dickneite, G., Pragst, I.

Journal:

Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 457 KB

english, 2014

64

Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model

Kaspereit, F., Hoffmann, S., Pragst, I., Dickneite, G.

Journal:

BJA British Journal of Anaesthesia

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

65

Influence of Antithrombin III on Coagulation and Inflammation in Porcine Septic Shock

Dickneite, G., Leithauser, B.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1999

Language:

english

File:

PDF, 572 KB

english, 1999

66

Correlation of Coagulation Markers and 4F-PCC-Mediated Reversal of Rivaroxaban in a Rabbit Model of Acute Bleeding

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Mueller-Cohrs, Jochen, Doerr, Baerbel, Niebl, Peter, Dickneite, Gerhard

Journal:

Thrombosis Research

Year:

2015

Language:

english

File:

PDF, 373 KB

english, 2015

67

Antithrombin III in Animal Models of Sepsis and Organ Failure

Dickneite, Gerhard

Journal:

Seminars in Thrombosis and Hemostasis

Year:

1998

Language:

english

File:

PDF, 1.59 MB

english, 1998

68

Characterization of the Coagulation Deficit in Porcine Dilutional Coagulopathy and Substitution with a Prothrombin Complex Concentrate

Dickneite, Gerhard, Doerr, Baerbel, Kaspereit, Franz

Journal:

Anesthesia & Analgesia

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008

69

Nonclinical analysis of the safety, pharmacodynamics, and pharmacokinetics of plasma-derived human FXIII concentrate in animals

Beyerle, Andrea, Solomon, Cristina, Dickneite, Gerhard, Herzog, Eva

Journal:

Pharmacology Research & Perspectives

Year:

2016

Language:

english

File:

PDF, 554 KB

english, 2016

70

Treatment of porcine sepsis with high-dose antithrombin III reduces tissue edema and effusion but does not increase risk for bleeding

Dickneite, G., Kroez, M.

Journal:

Blood Coagulation & Fibrinolysis

Year:

2001

Language:

english

File:

PDF, 811 KB

english, 2001

71

The effect of fibrinogen concentrate administration on coagulation abnormalities in a rat sepsis model

Kaspereit, Franz, Doerr, Baerbel, Dickneite, Gerhard

Journal:

Blood Coagulation & Fibrinolysis

Year:

2004

Language:

english

File:

PDF, 104 KB

english, 2004

72

Local activation of Coagulation Factor XIII reduces systemic complications and improves the survival of mice after Streptococcus pyogenes M1 skin infection

Deicke, Christin, Chakrakodi, Bhavya, Pils, Marina C., Dickneite, Gerhard, Johansson, Linda, Medina, Eva, Loof, Torsten G.

Journal:

International Journal of Medical Microbiology

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

73

ChemInform Abstract: Immunomodulation by the New Synthetic Thiazole Derivative Tiprotimod. Part 1. Synthesis and Structure-Activity Relationships.

FLEISCHMANN, K., SCHEUNEMANN, K. H., SCHORLEMMER, H. U., DICKNEITE, G., BLUMBACH, J., FISCHER, G., DRUECKHEIMER, W., SEDLACEK, H. H.

Journal:

Year:

1989

File:

PDF, 81 KB

1989

74

Animal model and clinical evidence indicating low thrombogenic potential of fibrinogen concentrate (Haemocomplettan P)

Dickneite, Gerhard, Pragst, Ingo, Joch, Christine, Bergman, Garrett E

Journal:

Blood Coagulation & Fibrinolysis

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

75

Utility of a high VWF

Raquet, Elmar, Stockschlaeder, Marcus, Mueller-Cohrs, Jochen, Zollner, Sabine, Pragst, Ingo, Dickneite, Gerhard

Journal:

Blood Coagulation & Fibrinolysis

Year:

2015

Language:

english

File:

PDF, 311 KB

english, 2015

76

206 RECOMBINANT HIRUDIN INHIBITS TISSUE FACTOR INDUCED DISSEMINATED INTRA-VASCULAR COAGULATION IN RABBITS

Dickneite, G., Kouz, J., Czech, J.

Journal:

Year:

1995

File:

PDF, 75 KB

1995

77

Effective Reversal of Edoxaban-associated Bleeding with Four-factor Prothrombin Complex Concentrate in a Rabbit Model of Acute Hemorrhage

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Doerr, Baerbel, Mueller-Cohrs, Jochen, Pragst, Ingo, Morishima, Yoshiyuki, Dickneite, Gerhard

Journal:

Year:

2015

Language:

english

File:

PDF, 716 KB

english, 2015

78

FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis

May, Frauke, Krupka, Jennifer, Fries, Marion, Thielmann, Ina, Pragst, Ingo, Weimer, Thomas, Panousis, Con, Nieswandt, Bernhard, Stoll, Guido, Dickneite, Gerhard, Schulte, Stefan, Nolte, Marc W.

Journal:

British Journal of Haematology

Year:

2016

Language:

english

File:

PDF, 597 KB

english, 2016

79

Prothrombin Complex Concentrate Versus Recombinant Factor VIIa for Reversal of Hemodilutional Coagulopathy in a Porcine Trauma Model

Dickneite, Gerhard, Dörr, Bärbel, Kaspereit, Franz, Tanaka, Kenichi A.

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

2010

Language:

english

File:

PDF, 308 KB

english, 2010

80

THE INFLUENCE OF ANTITHROMBIN III (AT III) ON EXPERIMENTAL SEPSIS

Dickneite, Gerhard

Journal:

Year:

1997

File:

PDF, 215 KB

1997

81

Four-factor prothrombin complex concentrate reverses apixaban-associated bleeding in a rabbit model of acute hemorrhage

Herzog, E., Kaspereit, F., Krege, W., Mueller-Cohrs, J., Doerr, B., Niebl, P., Dickneite, G.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 287 KB

english, 2015

82

Cefodizime, an aminothiazolyl cephalosporin. IV. Influence on the immune system.

LIMBERT, MICHAEL, BARTLETT, ROBERT R., DICKNEITE, GERHARD, KLESEL, NORBERT, SCHORLEMMER, HANS ULRICH, SEIBERT, GERHARD, WINKLER, IRVIN, SCHRINNER, ELMAR

Journal:

The Journal of Antibiotics

Year:

1984

Language:

english

File:

PDF, 4.14 MB

english, 1984

83

Targeted inactivation of the mouse locus encoding coagulation factor XII-A: Hemostatic abnormalities in mutant mice and characterization of the coagulation deficit

Lauer, Peter, Metzner, Hubert J., Zettlmei\ss l, Gerd, Li, Meng, Smith, Austin G., Lathe, Richard, Dickneite, Gerhard

Journal:

Thrombosis and Haemostasis

Year:

2002

Language:

english

File:

PDF, 309 KB

english, 2002

84

Influence of Recombinant Hirudin on Tissue-Factor-Induced Activation of Coagulation in Rabbits

Kouz, Jalal, Czech, J&ouml, rg, Nicolay, Uwe, Dickneite, Gerhard

Journal:

Pathophysiology of Haemostasis and Thrombosis

Year:

1996

File:

PDF, 2.62 MB

1996

85

1528

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Doerr, Baerbel, Mischnik, Marcel, Pragst, Ingo, Dickneite, Gerhard

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 413 KB

english, 2016

86

1504

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Doerr, Baerbel, Mischnik, Marcel, Pragst, Ingo, Dickneite, Gerhard

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 401 KB

english, 2016

87

Coagulation factor XIII: a multifunctional transglutaminase with clinical potential in a range of conditions

Dickneite, G., Herwald, H., Korte, W., Allanore, Y., Denton, C. P., Matucci Cerinic, M.

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 557 KB

english, 2015

88

Evaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice

Dardik, Rima, Leor, Jonathan, Skutelsky, Ehud, Castel, David, Holbova, Radka, Schiby, Ginette, Shaish, Aviv, Dickneite, Gerhard, Loscalzo, Joseph, Inbal, Aida

Journal:

Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 339 KB

english, 2006

89

The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats

Krupka, Jennifer, May, Frauke, Weimer, Thomas, Pragst, Ingo, Kleinschnitz, Christoph, Stoll, Guido, Panousis, Con, Dickneite, Gerhard, Nolte, Marc W., Meuth, Sven G.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.79 MB

english, 2016

90

Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence?

Dickneite, Gerhard, Hoffman, Maureane

Journal:

Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 767 KB

english, 2014

91

Targeted Inactivation of the Mouse Locus Encoding Coagulation Factor XIII-A: Hemostatic Abnormalities in Mutant Mice and Characterization of the Coagulation Deficit

Lauer, Peter, Metzner, Hubert, Zettlmeißl, Gerd, Li, Meng, Smith, Austin, Lathe, Richard, Dickneite, Gerhard

Journal:

Thrombosis and Haemostasis

Year:

2002

Language:

english

File:

PDF, 320 KB

english, 2002

92

Development of an Anti-Bleeding Agent for Recombinant Hirudin Induced Skin Bleeding in the Pig

Dickneite, Gerhard, Nicolay, Uwe, Friesen, Heinz-Jürgen, Reers, Martin

Journal:

Thrombosis and Haemostasis

Year:

1998

Language:

english

File:

PDF, 104 KB

english, 1998

93

Development of an Anti-Bleeding Agent for Recombinant Hirudin Induced Skin Bleeding in the Pig

Dickneite, Gerhard, Nicolay, Uwe, Friesen, Heinz-Jürgen, Reers, Martin

Journal:

Thrombosis and Haemostasis

Year:

1998

File:

PDF, 104 KB

1998

94

Tissue distribution of rIXâFP after intravenous application to rodents

Herrmann, Sabrina, Doerr, BÃ¤rbel, May, Frauke, Kuehnemuth, Benjamin, Cherpokova, Deya, Herzog, Eva, Dickneite, Gerhard, Nolte, Marc W.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2020

File:

PDF, 33.08 MB

2020

95

Evaluation of urinary biomarkers for early detection of acute kidney injury in a rat nephropathy model

Kohl, Kristina, Herzog, Eva, Dickneite, Gerhard, Pestel, Sabine

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2020

File:

PDF, 4.12 MB

2020