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51

Complement pathways in periodontitis and targeted therapeutic intervention

Toshiharu Abe, Robert A. DeAngelis, John D. Lambris, George Hajishengallis

Journal:

Year:

2012

Language:

english

File:

PDF, 74 KB

english, 2012

52

The use of rodent models to investigate host–bacteria interactions related to periodontal diseases

Dana T. Graves, Daniel Fine, Yen-Tung A. Teng, Thomas E. Van Dyke, George Hajishengallis

Journal:

Journal of Clinical Periodontology

Year:

2008

Language:

english

File:

PDF, 305 KB

english, 2008

53

Structure–activity correlations of variant forms of the B pentamer of Escherichia coli type II heat-labile enterotoxin LT-IIb with Toll-like receptor 2 binding

Cody, Vivian, Pace, Jim, Nawar, Hesham F., King-Lyons, Natalie, Liang, Shuang, Connell, Terry D., Hajishengallis, George

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

54

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

G. Hajishengallis, R.J. Lamont

Journal:

Molecular Oral Microbiology

Year:

2012

Language:

english

File:

PDF, 185 KB

english, 2012

55

Inhibition of Porphyromonas gingivalis-induced periodontal bone loss by CXCR4 antagonist treatment

M.L. McIntosh, G. Hajishengallis

Journal:

Molecular Oral Microbiology

Year:

2012

Language:

english

File:

PDF, 251 KB

english, 2012

56

[Advances in Experimental Medicine and Biology] Current Topics in Innate Immunity II Volume 946 || NK/DC Crosstalk in Anti-viral Response

Lambris, John D., Hajishengallis, George

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

57

Type II heat-labile enterotoxins: Structure, function, and immunomodulatory properties

Hajishengallis, George, Connell, Terry D.

Journal:

Veterinary Immunology and Immunopathology

Year:

2013

Language:

english

File:

PDF, 595 KB

english, 2013

58

[Advances in Experimental Medicine and Biology] Current Topics in Innate Immunity II Volume 946 || Nuclear Factor-κB in Immunity and Inflammation: The Treg and Th17 Connection

Lambris, John D., Hajishengallis, George

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

59

[Advances in Experimental Medicine and Biology] Current Topics in Innate Immunity II Volume 946 || A Conserved Host and Pathogen Recognition Site on Immunoglobulins: Structural and Functional Aspects

Lambris, John D., Hajishengallis, George

Year:

2012

Language:

english

File:

PDF, 1.85 MB

english, 2012

60

[Advances in Experimental Medicine and Biology] Current Topics in Innate Immunity II Volume 946 || Function of Act1 in IL-17 Family Signaling and Autoimmunity

Lambris, John D., Hajishengallis, George

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

61

Editorial: A Toll gate to escape T cells

Hajishengallis, G.

Journal:

Journal of Leukocyte Biology

Year:

2013

Language:

english

File:

PDF, 369 KB

english, 2013

62

Psychotropic drugs and their impact on the treatment of paediatric dental patients

E. Hajishengallis

Journal:

European Archives of Paediatric Dentistry

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

63

Aegean reflections on innate immunity

Hajishengallis, George, Mantovani, Alberto, Moretta, Alessandro, Lambris, John D

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 652 KB

english, 2013

64

Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response

Hajishengallis, George

Journal:

Trends in Immunology

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

65

[Advances in Experimental Medicine and Biology] Current Topics in Innate Immunity II Volume 946 || Granzyme B: A New Crossroad of Complement and Apoptosis

Lambris, John D., Hajishengallis, George

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

66

Neutrophil Homeostasis and Periodontal Health in Children and Adults

Hajishengallis, E., Hajishengallis, G.

Journal:

Journal of Dental Research

Year:

2014

Language:

english

File:

PDF, 539 KB

english, 2014

67

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss

Moutsopoulos, N. M., Konkel, J., Sarmadi, M., Eskan, M. A., Wild, T., Dutzan, N., Abusleme, L., Zenobia, C., Hosur, K. B., Abe, T., Uzel, G., Chen, W., Chavakis, T., Holland, S. M., Hajishengallis, G.

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 1.97 MB

english, 2014

68

TLR-signaling Networks: An Integration of Adaptor Molecules, Kinases, and Cross-talk

Brown, J., Wang, H., Hajishengallis, G. N., Martin, M.

Journal:

Journal of Dental Research

Year:

2011

Language:

english

File:

PDF, 910 KB

english, 2011

69

Porphyromonas gingivalis as a Potential Community Activist for Disease

Darveau, R. P., Hajishengallis, G., Curtis, M. A.

Journal:

Journal of Dental Research

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

70

Optimization of the ligature-induced periodontitis model in mice

Abe, Toshiharu, Hajishengallis, George

Journal:

Journal of Immunological Methods

Year:

2013

Language:

english

File:

PDF, 830 KB

english, 2013

71

Role of complement in host–microbe homeostasis of the periodontium

Hajishengallis, George, Abe, Toshiharu, Maekawa, Tomoki, Hajishengallis, Evlambia, Lambris, John D.

Journal:

Seminars in Immunology

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

72

Complement involvement in periodontitis: Mechanisms and therapeutic intervention

Hajishengallis, G., Maekawa, T., Abe, T., Hajishengallis, E., Reis, E., DeAngelis, R., Lambris, J.

Journal:

Molecular Immunology

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

73

Potential for Immunological and Microbiological Intervention against Porphyromonas gingivalis Infection

Hajishengallis, George

Journal:

Journal of Oral Biosciences

Year:

2007

Language:

english

File:

PDF, 179 KB

english, 2007

74

Immune Evasion Strategies of Porphyromonas gingivalis

Hajishengallis, George

Journal:

Journal of Oral Biosciences

Year:

2011

Language:

english

File:

PDF, 302 KB

english, 2011

75

Novel Inflammatory Pathways in Periodontitis

Hajishengallis, G., Sahingur, S. E.

Journal:

Advances in Dental Research

Year:

2014

Language:

english

File:

PDF, 551 KB

english, 2014

76

Genetic and Intervention Studies Implicating Complement C3 as a Major Target for the Treatment of Periodontitis

Maekawa, T., Abe, T., Hajishengallis, E., Hosur, K. B., DeAngelis, R. A., Ricklin, D., Lambris, J. D., Hajishengallis, G.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 789 KB

english, 2014

77

Illuminating the latest advances in innate immunity on the island of the sun god

Hajishengallis, George, Lambris, John D

Journal:

Expert Review of Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 147 KB

english, 2010

78

Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin

Mitroulis, I., Kang, Y.-Y., Gahmberg, C. G., Siegert, G., Hajishengallis, G., Chavakis, T., Choi, E.-Y.

Journal:

Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 200 KB

english, 2013

79

Etiology of leukocyte adhesion deficiency-associated periodontitis revisited: not a raging infection but a raging inflammatory response

Hajishengallis, George, Moutsopoulos, Niki M

Journal:

Expert Review of Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 302 KB

english, 2014

80

Breaking bad: Manipulation of the host response by Porphyromonas gingivalis

Hajishengallis, George, Lamont, Richard J.

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 561 KB

english, 2014

81

Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis

Zenobia, Camille, Luo, Xiao Long, Hashim, Ahmed, Abe, Toshiharu, Jin, Lijian, Chang, Yucheng, Jin, Zhi Chao, Sun, Jian Xun, Hajishengallis, George, Curtis, Mike A., Darveau, Richard P.

Journal:

Cellular Microbiology

Year:

2013

Language:

english

File:

PDF, 531 KB

english, 2013

82

Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis

Hajishengallis, G., McIntosh, M.L., Nishiyama, S.-I., Yoshimura, F.

Journal:

Molecular Oral Microbiology

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

83

The inflammophilic character of the periodontitis-associated microbiota

Hajishengallis, G.

Journal:

Molecular Oral Microbiology

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

84

Leukocyte integrins: Role in leukocyte recruitment and as therapeutic targets in inflammatory disease

Mitroulis, Ioannis, Alexaki, Vasileia I., Kourtzelis, Ioannis, Ziogas, Athanassios, Hajishengallis, George, Chavakis, Triantafyllos

Journal:

Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 1003 KB

english, 2015

85

Topical treatment with probiotic Lactobacillus brevis CD2 inhibits experimental periodontal inflammation and bone loss

Maekawa, T., Hajishengallis, G.

Journal:

Journal of Periodontal Research

Year:

2014

Language:

english

File:

PDF, 333 KB

english, 2014

86

Intracellular Signaling and Cytokine Induction upon Interactions of Porphyromonas gingivalis Fimbriae with Pattern‐Recognition Receptors

Hajishengallis, George, Sojar, Hakimuddin, Genco, Robert J., DeNardin, Ernesto

Journal:

Immunological Investigations

Year:

2004

Language:

english

File:

PDF, 334 KB

english, 2004

87

Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis

Hajishengallis, G., Chavakis, T., Hajishengallis, E., Lambris, J. D.

Journal:

Journal of Leukocyte Biology

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

88

The enduring importance of animal modelsin understanding periodontal disease

Hajishengallis, George, Lamont, Richard J, Graves, Dana T

Journal:

Year:

2015

Language:

english

File:

PDF, 976 KB

english, 2015

89

The A Subunit of Type IIb Enterotoxin (LT-IIb) Suppresses the Proinflammatory Potential of the B Subunit and Its Ability to Recruit and Interact with TLR2

Liang, S., Wang, M., Triantafilou, K., Triantafilou, M., Nawar, H. F., Russell, M. W., Connell, T. D., Hajishengallis, G.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 789 KB

english, 2007

90

Regulation of Osteoclast Homeostasis and Inflammatory Bone Loss by MFG-E8

Abe, T., Shin, J., Hosur, K., Udey, M. C., Chavakis, T., Hajishengallis, G.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

91

Ganglioside GD1a Is an Essential Coreceptor for Toll-like Receptor 2 Signaling in Response to the B subunit of Type IIb Enterotoxin

Liang, S., Wang, M., Tapping, R. I., Stepensky, V., Nawar, H. F., Triantafilou, M., Triantafilou, K., Connell, T. D., Hajishengallis, G.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 648 KB

english, 2006

92

Complement Receptor 3 Blockade Promotes IL-12-Mediated Clearance of Porphyromonas gingivalis and Negates Its Virulence In Vivo

Hajishengallis, G., Shakhatreh, M.-A. K., Wang, M., Liang, S.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 525 KB

english, 2007

93

TLR2 Transmodulates Monocyte Adhesion and Transmigration via Rac1- and PI3K-Mediated Inside-Out Signaling in Response to Porphyromonas gingivalis Fimbriae

Harokopakis, E., Albzreh, M. H., Martin, M. H., Hajishengallis, G.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 526 KB

english, 2006

94

Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function

Hajishengallis, G., Wang, M., Liang, S., Triantafilou, M., Triantafilou, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 1.30 MB

english, 2008

95

Counteracting Interactions between Lipopolysaccharide Molecules with Differential Activation of Toll-Like Receptors

Hajishengallis, G., Martin, M., Schifferle, R. E., Genco, R. J.

Journal:

Infection and Immunity

Year:

2002

Language:

english

File:

PDF, 161 KB

english, 2002

96

The C5a Receptor Impairs IL-12-Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss

Liang, S., Krauss, J. L., Domon, H., McIntosh, M. L., Hosur, K. B., Qu, H., Li, F., Tzekou, A., Lambris, J. D., Hajishengallis, G.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 740 KB

english, 2011

97

Induction of Protective Immunity against Streptococcus mutans Colonization after Mucosal Immunization with Attenuated Salmonella enterica Serovar Typhimurium Expressing an S. mutans Adhesin under the Control of In Vivo-Inducible nirB Promoter

Huang, Y., Hajishengallis, G., Michalek, S. M.

Journal:

Infection and Immunity

Year:

2001

Language:

english

File:

PDF, 133 KB

english, 2001

98

Dependence of Bacterial Protein Adhesins on Toll-Like Receptors for Proinflammatory Cytokine Induction

Hajishengallis, G., Martin, M., Sojar, H. T., Sharma, A., Schifferle, R. E., DeNardin, E., Russell, M. W., Genco, R. J.

Journal:

Clinical and Vaccine Immunology

Year:

2002

Language:

english

File:

PDF, 236 KB

english, 2002

99

Mapping of a Microbial Protein Domain Involved in Binding and Activation of the TLR2/TLR1 Heterodimer

Liang, S., Hosur, K. B., Lu, S., Nawar, H. F., Weber, B. R., Tapping, R. I., Connell, T. D., Hajishengallis, G.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 528 KB

english, 2009

100

Recombinant Antigen-Enterotoxin A2/B Chimeric Mucosal Immunogens Differentially Enhance Antibody Responses and B7-Dependent Costimulation of CD4+ T Cells

Martin, M., Hajishengallis, G., Metzger, D. J., Michalek, S. M., Connell, T. D., Russell, M. W.

Journal:

Infection and Immunity

Year:

2001

Language:

english

File:

PDF, 367 KB

english, 2001