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51

Cellular metabolism of familial British dementia-associated BRI-L

Seong-Hun Kim, Rong Wang, Gopal Thinakaran, Joseph Bass, Donald F. Steiner, John W. Creemers, Sangram S. Sisodia

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 187 KB

english, 2000

52

Cell biology of APP and PS1

Gopal Thinakaran

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

53

O3-05-07 Association of γ-secretase components with lipid rafts

Gopal Thinakaran, Kulandaivelu S. Vetrivel, Jae-Yoon Leem, Renaldo Drisdel, Haipeng Cheng, Margaret Veselits, Takashi Sakurai, Nobuyuki Nukina, William N. Green

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

54

95 Synthesis and metabolism of presenilin 1 with mutations linked to familial Alzheimer's disease in transgenic mice

D. Borchelt, M. Lee, G. Thinakaran, P.C. Wong, H.H.H.H. Slunt, T. Ratovitski, G. Kim, N.A. Jenkins, N.G. Copeland, Donald Price

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 147 KB

english, 1996

55

173 Cellular sites of APP processing and all production

S.S. Sisodia, G. Thinakaran, D.B. Teplow, R. Siman, M. Savage, B. Greenberg, B. Lamb, R. Wang, D.L. Price, D. Borchelt

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 149 KB

english, 1996

56

388 Phosphorylation of ß-amyloid precursor protein at two distinct cellular locations

J. Walters, A. Hung, G. Thinakaran, S. Sisodia, D. Selkoe, C. Haassl

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 123 KB

english, 1996

57

443 Characterization of presenilin 1 (PS1) with mutations linked to familial Alzheimer's disease: Metabolism, topology and influence on Aβ generation

G. Thinakaran, A. Doan, M.K. Lee, H.H. Slunt, M. Savage, B. Greenberg, R. Wang, D.L. Price, S.S. Sisodia

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 139 KB

english, 1996

58

Generation of APLP2 KO Mice and Early Postnatal Lethality in APLP2/APP Double KO Mice

C.S. von Koch, H. Zheng, H. Chen, M. Trumbauer, G. Thinakaran, L.H.T. van der Ploeg, D.L. Price, S.S. Sisodia

Journal:

Neurobiology of Aging

Year:

1997

Language:

english

File:

PDF, 360 KB

english, 1997

59

Amyloid Precursor Proteins Inhibit Heme Oxygenase Activity and Augment Neurotoxicity in Alzheimer's Disease

Masaaki Takahashi, Sylvain Doré, Christopher D Ferris, Taisuke Tomita, Akira Sawa, Herman Wolosker, David R Borchelt, Takeshi Iwatsubo, Seong-Hun Kim, Gopal Thinakaran, Sangram S Sisodia, Solomon H Sn

Journal:

Year:

2000

Language:

english

File:

PDF, 902 KB

english, 2000

60

Protein Topology of Presenilin 1

Andrew Doan, Gopal Thinakaran, David R Borchelt, Hilda H Slunt, Tamara Ratovitsky, Marcia Podlisny, Dennis J Selkoe, Mary Seeger, Samuel E Gandy, Donald L Price, Sangram S Sisodia

Journal:

Year:

1996

Language:

english

File:

PDF, 1.66 MB

english, 1996

61

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Gopal Thinakaran, David R Borchelt, Michael K Lee, Hilda H Slunt, Lia Spitzer, Grace Kim, Tamara Ratovitsky, Frances Davenport, Christer Nordstedt, Mary Seeger, John Hardy, Allan I Levey, Samuel E Gan

Journal:

Year:

1996

Language:

english

File:

PDF, 5.23 MB

english, 1996

62

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David R. Borchelt, Gopal Thinakaran, Christopher B. Eckman, Michael K. Lee, Frances Davenport, Tamara Ratovitsky, Cristian-Mihail Prada, Grace Kim, Sophia Seekins, Debra Yager, Hilda H. Slunt, Rong Wa

Journal:

Year:

1996

Language:

english

File:

PDF, 383 KB

english, 1996

63

Effects of PS1 Deficiency on Membrane Protein Trafficking in Neurons

Satoshi Naruse, Gopal Thinakaran, Jin-Jun Luo, John W Kusiak, Taisuke Tomita, Takeshi Iwatsubo, Xiaozhong Qian, David D Ginty, Donald L Price, David R Borchelt, Philip C Wong, Sangram S Sisodia

Journal:

Year:

1998

Language:

english

File:

PDF, 242 KB

english, 1998

64

Function and Dysfunction of the Presenilins

Sangram S. Sisodia, Seong H. Kim, Gopal Thinakaran

Journal:

The American Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 118 KB

english, 1999

65

O2-03-01: Exploring β-secretase activity in lipid raft microdomains

Kulandaivelu S. Vetrivel, Xavier Meckler, Ying Chen, Phuong D. Nguyen, Tong Li, Philip C. Wong, Nabil G. Seidah, Robert Vassar, Gopal Thinakaran

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

66

PL-04-03: Function and dysfunction of presenilins

Gopal Thinakaran

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

67

O4-06-05: Presenilin-dependent changes in synaptic components and associated signaling cascades

Angèle Parent, Natalie Y. Barnes, Jun Shi, Gopal Thinakaran

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

68

Dimebon®: A Clinically Promising Drug for Alzheimer's Disease, Regulates Amyloid-Beta Metabolism in Cultured Cells, In Isolated Nerve Terminals, and In the Interstitial Fluid of the Living Rodent Brain

Sam Gandy, John Cirrito, John Steele, Soong Ho Kim, Gopal Thinakaran, David Westaway, Paul Fraser, Peter St George Hyslop, Mary Sano, Ilya Bezprozvanny, Michelle E. Ehrlich, David M. Holtzman

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

69

224 Expression of presenilin 1 and 2 in human and mouse tissues

M.K. Lee, H.H. Slunt, G. Thinakaran, D.L. Price, S. Sisodia

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 154 KB

english, 1996

70

FRET Reveals Novel Protein-Receptor Interaction of Bone Morphogenetic Proteins Receptors and Adaptor Protein 2 at the Cell Surface

Bragdon, Beth, Thinakaran, Shayamala, Bonor, Jeremy, Underhill, T. Michael, Petersen, Nils O., Nohe, Anja

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 528 KB

english, 2009

71

Casein Kinase 2 β-Subunit Is a Regulator of Bone Morphogenetic Protein 2 Signaling

Bragdon, Beth, Thinakaran, Shayamala, Moseychuk, Oleksandra, King, Daniel, Young, Kira, Litchfield, David W., Petersen, Nils O., Nohe, Anja

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 543 KB

english, 2010

72

Identification of the role of presenilins beyond Alzheimer’s disease

Gopal Thinakaran, Angèle T Parent

Journal:

Pharmacological Research

Year:

2004

Language:

english

File:

PDF, 98 KB

english, 2004

73

Studies on the Metabolism and Biological Function of APLP2

S. S. SISODIA, G. THINAKARAN, H. H. SLUNT, C. A. KITT, C. S. VON KOCH, R. R. REED, H. Z. ZHENG, D. L. PRICE

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 290 KB

english, 1996

74

Mechanisms of Disease: new therapeutic strategies for Alzheimer's disease—targeting APP processing in lipid rafts

Cheng, Haipeng, Vetrivel, Kulandaivelu S, Gong, Ping, Meckler, Xavier, Parent, Angèle, Thinakaran, Gopal

Journal:

Nature Clinical Practice Neurology

Year:

2007

Language:

english

File:

PDF, 408 KB

english, 2007

75

Ca2+ Influx through Store-operated Ca2+ Channels Reduces Alzheimer Disease -Amyloid Peptide Secretion

Zeiger, W., Vetrivel, K. S., Buggia-Prevot, V., Nguyen, P. D., Wagner, S. L., Villereal, M. L., Thinakaran, G.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 4.46 MB

english, 2013

76

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta -amyloid peptides

Greenfield, J. P., Tsai, J., Gouras, G. K., Hai, B., Thinakaran, G., Checler, F., Sisodia, S. S., Greengard, P., Xu, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 434 KB

english, 1999

77

Structural domain requirements for presenilin endoproteolysis and Aβ42 overproduction

Leem, Jae Yoon, Saura, Carlos, Tomita, Taisuke, Iwatsubo, Takeshi, Thinakaran, Gopal

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 160 KB

english, 2000

78

Influence of PS and FAD-linked PS variants on the mammalian unfolded protein response

Sato, Naoyuki, Kim, Seong-Hun, Veselits, Margaret, Chu, Su, Sisodia, Sangram S., Thinakaran, Gopal

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 182 KB

english, 2000

79

P3-337: S-palmitoylation targets BACE-1 to lipid rafts

Meckler, Xavier, Vetrivel, Kulandaivelu S., Chen, Ying, Li, Tong, Seidah, Nabil G., Vassar, Robert, Wong, Philip C., Fukata, Masaki, Thinakaran, Gopal

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

80

Intravenous lidocaine does not attenuate the hemodynamic response of children to laryngoscopy and tracheal intubation

Meckler, Xavier, Vetrivel, Kulandaivelu S., Chen, Ying, Li, Tong, Seidah, Nabil G., Vassar, Robert, Wong, Philip C., Fukata, Masaki, Thinakaran, Gopal

Journal:

The Journal of Emergency Medicine

Year:

1991

Language:

english

File:

PDF, 106 KB

english, 1991

81

Secretase-dependent APP-CTF accumulation influences differentially axodendritic development and associated signalling

Deyts, Carole, Herrera, Stacy, Das, Shibandri, Clutter, Mary, Thinakaran, Gopal, Parent, Angèle

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

82

APP intracellular domain enhances neurite outgrowth through gαs coupling to adenylate cyclase signaling

Deyts, Carole, Vetrivel, Kulandaivelu, Shepherd, Yumiko, Thinakaran, Gopal, Parent, Angèle

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

83

P4-310 Role of presenilin1-β-catenin interaction in embryonic development

Liu, Li, Jankowsky, Joanna, Kordylewska, Anna, Veselits, Margaret, Utset, Manuel, Borchelt, David, Thinakaran, Gopal

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

84

P3-195 Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties

Ito, Daisuke, Walker, John R., Thompson, Charlie S., Moroz, Isabella, Veselits, Margaret L., Xu, Guilian M., Borchelt, David R., Hakim, Antoine M., Fienberg, Allen A., Thinakaran, Gopal

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

85

Assessment of Normal and Mutant Human Presenilin Function in Caenorhabditis elegans

Diane Levitan, Timothy G. Doyle, Denise Brousseau, Michael K. Lee, Gopal Thinakaran, Hilda H. Slunt, Sangram S. Sisodia and Iva Greenwald

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.52 MB

english, 1996

86

Generation of Alzheimer β -Amyloid Protein in the Trans-Golgi Network in the Apparent Absence of Vesicle Formation

Huaxi Xu, David Sweeney, Rong Wang, Gopal Thinakaran, Amy C. Y. Lo, Sangram S. Sisodia, Paul Greengard and Sam Gandy

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.19 MB

english, 1997

87

Endoplasmic Reticulum and Trans-Golgi Network Generate Distinct Populations of Alzheimer β -Amyloid Peptides

Jeffrey P. Greenfield, Julia Tsai, Gunnar K. Gouras, Bing Hai, Gopal Thinakaran, Frederic Checler, Sangram S. Sisodia, Paul Greengard and Huaxi Xu

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.90 MB

english, 1999

88

Amyloid Precursor Protein Trafficking, Processing, and Function

Thinakaran, G., Koo, E. H.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 782 KB

english, 2008

89

[IEEE 2000 IEEE Workshop on SiGNAL PROCESSING SYSTEMS. SiPS 2000. Design and Implementation - Lafayette, LA, USA (11-13 Oct. 2000)] 2000 IEEE Workshop on SiGNAL PROCESSING SYSTEMS. SiPS 2000. Design and Implementation (Cat. No.00TH8528) - Fast shape decoding for MPEG-4 video

Thinakaran, J., Duan-Juat Ho,, Nam Ling,

Year:

2000

Language:

english

File:

PDF, 480 KB

english, 2000

90

[IEEE 2012 IEEE Computer Society Annual Symposium on VLSI (ISVLSI) - Amherst, MA, USA (2012.08.19-2012.08.21)] 2012 IEEE Computer Society Annual Symposium on VLSI - SCOC IP Cores for Custom Built Supercomputing Nodes

Nagarajan, Venkateswaran, Hariharan, Rajagopal, Srinivasan, Vinesh, Kannan, Ram Srivatsa, Thinakaran, Prashanth, Sankaran, Vigneshwaren, Vasudevan, Bharanidharan, Mukundrajan, Ravindhiran, Nachiappan,

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

91

[IEEE 2012 IEEE Computer Society Annual Symposium on VLSI (ISVLSI) - Amherst, MA, USA (2012.08.19-2012.08.21)] 2012 IEEE Computer Society Annual Symposium on VLSI - Compilation Accelerator on Silicon

Nagarajan, Venkateswaran, Srinivasan, Vinesh, Kannan, Ramsrivatsa, Thinakaran, Prashanth, Hariharan, Rajagopal, Vasudevan, Bharanidharan, Nachiappan, Nachiappan Chidambaram, Saravanan, Karthikeyan Pal

Year:

2012

Language:

english

File:

PDF, 497 KB

english, 2012

92

Amyloid $sZ-protein stimulates parallel increases in cellular levels of its precursor and amyloid precursor-like protein 2 (APLP2) in human cerebrovascular smooth muscle cells

Saporito-irwin, Susan M., Thinakaran, Gopal, Ruffini, Lynda, Sisodia, Sangram S., Van Nostrand, William E.

Journal:

Year:

1997

Language:

english

File:

PDF, 734 KB

english, 1997

93

Amyloidogenic processing of -amyloid precursor protein in intracellular compartments

Vetrivel, K. S., Thinakaran, G.

Journal:

Year:

2006

Language:

english

File:

PDF, 786 KB

english, 2006

94

[IEEE 2012 IEEE 11th International Conference on Trust, Security and Privacy in Computing and Communications (TrustCom) - Liverpool, United Kingdom (2012.06.25-2012.06.27)] 2012 IEEE 11th International Conference on Trust, Security and Privacy in Computing and Communications - Random4: An Application Specific Randomized Encryption Algorithm to Prevent SQL Injection

Avireddy, Srinivas, Perumal, Varalakshmi, Gowraj, Narayan, Kannan, Ram Srivatsa, Thinakaran, Prashanth, Ganapthi, Sundaravadanam, Gunasekaran, Jashwant Raj, Prabhu, Sruthi

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

95

Regulation of c-jun /AP-1 expression in rat L6 myoblasts

Thinakaran, Gopal, Bag, Jnanankur

Journal:

Biochemistry and Cell Biology

Year:

1993

Language:

english

File:

PDF, 1.25 MB

english, 1993

96

Risk factors for depression and anxiety among pregnant women in Hospital Tuanku Bainun, Ipoh, Malaysia

Fadzil, Ariff, Balakrishnan, Kartini, Razali, Rosdinom, Sidi, Hatta, Malapan, Thinakaran, Japaraj, Robert Peter, Midin, Marhani, Nik Jaafar, Nik Ruzyanei, Das, Srijit, Manaf, Mohd Rizal Abdul

Journal:

Asia-Pacific Psychiatry

Year:

2013

Language:

english

File:

PDF, 167 KB

english, 2013

97

[IEEE 2011 International Conference on Electrical Engineering and Informatics (ICEEI) - Bandung, Indonesia (2011.07.17-2011.07.19)] Proceedings of the 2011 International Conference on Electrical Engineering and Informatics - UKM C2M: A cluster control system for cluster computer developed using opensource software

Thinakaran, Rajermani, Sundararajan, Elankovan

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

98

Expression of the protooncogene c- jun is maintained during myogenic differentiation in rat L6 myoblasts

Thinakaran, Gopal, Bag, Jnanankur

Journal:

Biochemistry and Cell Biology

Year:

1993

Language:

english

File:

PDF, 1.48 MB

english, 1993

99

[IEEE 2013 IEEE Computer Society Annual Symposium on VLSI (ISVLSI) - Natal, Brazil (2013.08.5-2013.08.7)] 2013 IEEE Computer Society Annual Symposium on VLSI (ISVLSI) - Performance and energy efficient cache system design: Simultaneous execution of multiple applications on heterogeneous cores

Nagarajan, Venkateswaran, Lakshminarasimhan, Kartik, Sridhar, Akash, Thinakaran, Prashanth, Hariharan, Rajagopal, Srinivasan, Vinesh, Kannan, Ram Srivatsa, Sridharan, Aswin

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

100

Electro-Induced Coating of Chitosan on Centrifugal Spun Matrix – A Hybrid Composite for Biomedical Applications

Thinakaran, Senthilram, Loordhuswamy, Amalorpava Mary, Viswanathan, Nanthagopal, Rengaswami, Giri Dev Venkateshwarapuram

Journal:

Polymer-Plastics Technology and Engineering

Year:

2013

Language:

english

File:

PDF, 931 KB

english, 2013

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