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51

Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma

Tseng, Hsiang-chi, Xiong, Wei, Badeti, Saiaditya, Yang, Yan, Ma, Minh, Liu, Ting, Ramos, Carlos A., Dotti, Gianpietro, Fritzky, Luke, Jiang, Jie-gen, Yi, Qing, Guarrera, James, Zong, Wei-Xing, Liu, Ch

Journal:

Nature Communications

Year:

2020

File:

PDF, 2.37 MB

2020

52

Transgenic expression of IL-10 by lentiviral vectors for increasing the anti-inflammatory efficacy of mesenchymal stromal cells

Gullotta, Fabiana, Noviello, Maddalena, Stanco, Deborah, Andolfi, Grazia, Bernardo, Maria Ester, Bonini, Maria Chiara, Banfi, Giuseppe, Peretti, Giuseppe, De Girolamo, Laura, Dotti, Gianpietro, Gregor

Journal:

Journal of Biotechnology

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

53

Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells

Tanaka, Miyuki, Tashiro, Haruko, Omer, Bilal, Lapteva, Natasha, Ando, Jun, Ngo, Minhtran, Mehta, Birju, Dotti, Gianpietro, Kinchington, Paul R, Leen, Ann M, Rossig, Claudia, Rooney, Cliona M

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 13.92 MB

english, 2017

54

Adoptive T-cell immunotherapy of chronic lymphocytic leukaemia

Aaron E. Foster, Malcolm K. Brenner, Gianpietro Dotti

Journal:

Best Practice & Research Clinical Haematology

Year:

2008

Language:

english

File:

PDF, 593 KB

english, 2008

55

The Other Face of Chimeric Antigen Receptors

Dotti, Gianpietro

Journal:

Molecular Therapy

Year:

2014

Language:

english

File:

PDF, 365 KB

english, 2014

56

Accelerated Production of Antigen-specific T Cells for Preclinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)

Vera, Juan F., Brenner, Lara J., Gerdemann, Ulrike, Ngo, Minhtran C., Sili, Uluhan, Liu, Hao, Wilson, John, Dotti, Gianpietro, Heslop, Helen E., Leen, Ann M., Rooney, Cliona M.

Journal:

Journal of Immunotherapy

Year:

2010

Language:

english

File:

PDF, 687 KB

english, 2010

57

Characterization and Functional Analysis of scFv-Based Cars to Redirect T Cells to IL13Rα2-Positive Glioma

Krenciute, Giedre, Krebs, Simone, Torres, David, Wu, Meng-Fen, Liu, Hao, Dotti, Gianpietro, Li, Xiao-Nan, Lesniak, Maciej S., Balyasnikova, Irina V., Gottschalk, Stephen

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

58

PPM1A and PPM1B act as IKKβ phosphatases to terminate TNFα-induced IKKβ-NF-κB activation

Wenjing Sun, Yang Yu, Gianpietro Dotti, Tao Shen, Xiaojie Tan, Barbara Savoldo, Amy K. Pass, Meijin Chu, Dekai Zhang, Xiongbin Lu, Songbin Fu, Xia Lin, Jianhua Yang

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

59

Control of leukemia relapse after allogeneic hematopoietic stem cell transplantation

Dotti, Gianpietro

Journal:

Current Opinion in Hematology

Year:

2015

Language:

english

File:

PDF, 363 KB

english, 2015

60

721. Safety of Multiple Doses of CAR T Cells

Fousek, Kristen, Rouce, Rayne, Ahmed, Nabil, Gottschalk, Stephen, Savoldo, Barbara, Dotti, Gianpietro, Ramos, Carlos, Louis, Chrystal, Rooney, Cliona, Brenner, Malcolm, Heslop, Helen

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 272 KB

english, 2015

61

410. The Development of HLAnull K562 Cells Expressing CD1d and Co-Stimulatory Molecules as Artificial Antigen-Presenting Cells for Clinical Scale Expansion of NKT Cells With Superior In Vivo Persistence and Anti-Tumor Potential

Tian, Gengwen, Jena, Bipulendu, Liu, Daofeng, Heczey, Andras, Torikai, Hiroki, Lee, Dean, Dotti, Gianpietro, Cooper, Laurence, Metelitsa, Leonid S.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 276 KB

english, 2015

62

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

Hu, Quanyin, Sun, Wujin, Wang, Jinqiang, Ruan, Huitong, Zhang, Xudong, Ye, Yanqi, Shen, Song, Wang, Chao, Lu, Weiyue, Cheng, Ke, Dotti, Gianpietro, Zeidner, Joshua F., Wang, Jun, Gu, Zhen

Journal:

Nature Biomedical Engineering

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

63

Bystander Transfer of Functional Human CD40 Ligand from Gene-Modified Fibroblasts to B-Chronic Lymphocytic Leukemia Cells

Biagi, Ettore, Yvon, Eric, Dotti, Gianpietro, Amrolia, Persis J., Takahashi, Satoshi, Popat, Uday, Marini, Frank, Andreeff, Michael, Brenner, Malcolm K., Rousseau, Raphaël F.

Journal:

Human Gene Therapy

Year:

2003

Language:

english

File:

PDF, 440 KB

english, 2003

64

GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockade

Gargett, Tessa, Yu, Wenbo, Dotti, Gianpietro, Yvon, Eric S., Christo, Susan N., Hayball, John D., Lewis, Ian D., Brenner, Malcolm K., Brown, Michael P.

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

65

412. Development of GD2-Specific Immunoliposomes for Immunotherapy of Neuroblastoma

Huang, Wei, Liu, Daofeng, Guo, Linjie, Dotti, Gianpietro, Metelitsa, Leonid S.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 301 KB

english, 2015

66

Charachterization and functional analysis of scFv-based CARs to redirect T cells to IL13Rα2-positive glioma

Krenciute, Giedre, Krebs, Simone, Torres, David, Dotti, Gianpietro, Lesniak, Maciej S, Balyasnikova, Irina V, Gottschalk, Stephen

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 255 KB

english, 2015

67

Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors

Karlsson, Hannah, Svensson, Emma, Gigg, Camilla, Jarvius, Malin, Olsson-Strömberg, Ulla, Savoldo, Barbara, Dotti, Gianpietro, Loskog, Angelica, Tasken, Kjetil

Journal:

Year:

2015

Language:

english

File:

PDF, 838 KB

english, 2015

68

ScaffoldâMediated Static Transduction of T Cells for CARâT Cell Therapy

Agarwalla, Pritha, Ogunnaike, Edikan A., Ahn, Sarah, Ligler, Frances S., Dotti, Gianpietro, Brudno, Yevgeny

Journal:

Advanced Healthcare Materials

Year:

2020

File:

PDF, 1.09 MB

2020

69

Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment

Robinson, Simon N., Thomas, Michael W., Simmons, Paul J., Lu, Junjun, Yang, Hong, Parmar, Simrit, Liu, Xiaoying, Shah, Nina, Martín-Antonio, Beatriz, Bollard, Catherine, Dotti, Gianpietro, Savoldo, Ba

Journal:

Year:

2014

Language:

english

File:

PDF, 452 KB

english, 2014

70

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

Di Stasi, Antonio, Tey, Siok-Keen, Dotti, Gianpietro, Fujita, Yuriko, Kennedy-Nasser, Alana, Martinez, Caridad, Straathof, Karin, Liu, Enli, Durett, April G., Grilley, Bambi, Liu, Hao, Cruz, Conrad R.

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 886 KB

english, 2011

71

Serial activation of the inducible caspase 9 safety switch after human stem cell transplantation

Zhou, Xiaoou, Naik, Swati, Dakhova, Olga, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

72

Optimization of the PiggyBac Transposon System for the Sustained Genetic Modification of Human T Lymphocytes

Nakazawa, Yozo, Huye, Leslie E., Dotti, Gianpietro, Foster, Aaron E., Vera, Juan F., Manuri, Pallavi R., June, Carl H., Rooney, Cliona M., Wilson, Matthew H.

Journal:

Journal of Immunotherapy

Year:

2009

Language:

english

File:

PDF, 994 KB

english, 2009

73

768. Redirected T Cells to Selectively Target Mature B Cell Derived Malignancies

Vera, Juan, Savoldo, Barbara, Vigouroux, Stephane, Biagi, Ettore, Pule, Martin, Rossig, Claudia, Brenner, Malcolm, Dotti, Gianpietro

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 84 KB

english, 2006

74

748. A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia

Enblad, Gunilla, Karlsson, Hannah, Wenthe, Jessica, Wikstrom, Kristina I., Essand, Magnus, Savoldo, Barbara, Dotti, Gianpietro, Hoglund, Martin, Hallbook, Helene, Brenner, Malcolm K., Hagberg, Hans, L

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 348 KB

english, 2016

75

Cancer Immunotherapy: PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy (Adv. Mater. 22/2018)

Zhang, Xudong, Wang, Chao, Wang, Jinqiang, Hu, Quanyin, Langworthy, Benjamin, Ye, Yanqi, Sun, Wujin, Lin, Jing, Wang, Tianfu, Fine, Jason, Cheng, Hao, Dotti, Gianpietro, Huang, Peng, Gu, Zhen

Journal:

Advanced Materials

Year:

2018

File:

PDF, 14.51 MB

2018

76

Photothermal Therapy: Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells (Adv. Mater. 23/2019)

Chen, Qian, Hu, Quanyin, Dukhovlinova, Elena, Chen, Guojun, Ahn, Sarah, Wang, Chao, Ogunnaike, Edikan A., Ligler, Frances S., Dotti, Gianpietro, Gu, Zhen

Journal:

Advanced Materials

Year:

2019

File:

PDF, 2.48 MB

2019

77

766. Immunotherapy for Her2-Positive Medulloblastoma: Regression of Experimental Tumors by Transfer of Her2-Redirected T Cells In Vivo

Ahmed, Nabil M., Ratnayake, Maheshika K., Savoldo, Barbara, Perlaky, Laszlo, Dotti, Gianpietro, Wels, Winfried, Bhattacharjee, Meenakshi B., Shine, H. David, Rooney, Cliona M., Heslop, Helen E., Gotts

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

78

PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor

Nakazawa, Yozo, Huye, Leslie E, Salsman, Vita S, Leen, Ann M, Ahmed, Nabil, Rollins, Lisa, Dotti, Gianpietro, Gottschalk, Stephen M, Wilson, Matthew H, Rooney, Cliona M

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 4.17 MB

english, 2011

79

Combining mTor Inhibitors With Rapamycin-resistant T Cells: A Two-pronged Approach to Tumor Elimination

Huye, Leslie E, Nakazawa, Yozo, Patel, Mayuri P, Yvon, Eric, Sun, Jiali, Savoldo, Barbara, Wilson, Matthew H, Dotti, Gianpietro, Rooney, Cliona M

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 915 KB

english, 2011

80

Antitumor Activity of EBV-specific T Lymphocytes Transduced With a Dominant Negative TGF-?? Receptor

Foster, Aaron E., Dotti, Gianpietro, Lu, An, Khalil, Mariam, Brenner, Malcolm K., Heslop, Helen E., Rooney, Cliona M., Bollard, Catherine M.

Journal:

Journal of Immunotherapy

Year:

2008

Language:

english

File:

PDF, 395 KB

english, 2008

81

Fludarabine Modulates Immune Response and Extends In Vivo Survival of Adoptively Transferred CD8 T Cells in Patients with Metastatic Melanoma

Wallen, Herschel, Thompson, John A., Reilly, J. Zachary, Rodmyre, Rebecca M., Cao, Jianhong, Yee, Cassian, Dotti, Gianpietro

Journal:

Year:

2009

Language:

english

File:

PDF, 512 KB

english, 2009

82

416. Immunotherapy of Hepatocellular Carcinoma With T Cells Engineered To Express Glypican-3-Specific Chimeric Antigen Receptors

Li, Wenpeng, Linjie, Guo, Ekaterina, Marinova, Gianpietro, Dotti, Stephen, Gottschalk, Leonid, Metelitsa, Andras, Heczey

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 499 KB

english, 2015

83

Effect of the protein tyrosine kinase inhibitor genistein on normal and leukaemic haemopoietic progenitor cells

CARMELO CARLO-STELLA, ESTER REGAZZI, DANIELA GARAU, LINA MANGONI, MARIA TERESA RIZZO, ANTONIO BONATI, GIANPIETRO DOTTI, CAMILLO ALMICI, VITTORIO RIZZOLI

Journal:

British Journal of Haematology

Year:

1996

Language:

english

File:

PDF, 646 KB

english, 1996

84

BRAF and MEK Inhibition Variably Affect GD2-specific Chimeric Antigen Receptor (CAR) T-Cell Function In Vitro

Gargett, Tessa, Fraser, Cara K., Dotti, Gianpietro, Yvon, Eric S., Brown, Michael P.

Journal:

Journal of Immunotherapy

Year:

2015

Language:

english

File:

PDF, 966 KB

english, 2015

85

Safety of multiple doses of car T cells

Fousek, Kristen, Rouce, Rayne, Ahmed, Nabil, Gottschalk, Stephen, Savoldo, Barbara, Dotti, Gianpietro, Ramos, Carlos, Louis, Chrystal U., Rooney, Cliona, Brenner, Malcom, Heslop, Helen

Journal:

Year:

2015

Language:

english

File:

PDF, 280 KB

english, 2015

86

Leucocyte alkaline phosphatase identifies terminally differentiated normal neutrophils and its lack in chronic myelogenous leukaemia is not dependent on p210 tyrosine kinase activity

Dotti, Gianpietro, Garattini, Enrico, Borleri, Gianmaria, Masuhara, Kensaku, Spinelli, Orietta, Barbui, Tiziano, Rambaldi, Alessandro

Journal:

British Journal of Haematology

Year:

1999

Language:

english

File:

PDF, 222 KB

english, 1999

87

Chimeric Antigen Receptor T-cells for B-cell Malignancies

Lichtman, Eben I., Dotti, Gianpietro

Journal:

Translational Research

Year:

2017

Language:

english

File:

PDF, 1.61 MB

english, 2017

88

An Update on Adoptive T-Cell Therapy and Neoantigen Vaccines

Ott, Patrick A., Dotti, Gianpietro, Yee, Cassian, Goff, Stephanie L.

Journal:

American Society of Clinical Oncology Educational Book

Year:

2019

Language:

english

File:

PDF, 480 KB

english, 2019

89

Immunological Synapse Predicts Effectiveness of Chimeric Antigen Receptor Cells

Xiong, Wei, Chen, Yuhui, Kang, Xi, Chen, Zhiying, Zheng, Peilin, Hsu, Yi-Hsin, Jang, Joon Hee, Qin, Lidong, Liu, Hao, Dotti, Gianpietro, Liu, Dongfang

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 2.87 MB

english, 2018

90

Enhancing Chimeric Antigen Receptor T cell Efficacy in Solid Tumors

FucÃ¡, Giovanni, Reppel, Loic, Landoni, Elisa, Savoldo, Barbara, Dotti, Gianpietro

Journal:

Clinical Cancer Research

Year:

2020

File:

PDF, 1.15 MB

2020

91

Clinical Responses in Patients Infused with T Lymphocytes Redirected to Target Kappa-Light Immunoglobulin Chain

Ramos, Carlos A., Savoldo, Barbara, Liu, Enli, Gee, Adrian P., Mei, Zhuyong, Grilley, Bambi, Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K., Dotti, Gianpietro

Journal:

Biology of Blood and Marrow Transplantation

Year:

2014

Language:

english

File:

PDF, 153 KB

english, 2014

92

From Monoclonal Antibodies to Chimeric Antigen Receptors for the Treatment of Human Malignancies

Caruana, Ignazio, Diaconu, Iulia, Dotti, Gianpietro

Journal:

Seminars in Oncology

Year:

2014

Language:

english

File:

PDF, 413 KB

english, 2014

93

Autologous Antileukemic Immune Response Induced by Chronic Lymphocytic Leukemia B Cells Expressing the CD40 Ligand and Interleukin 2 Transgenes

Takahashi, Satoshi, Rousseau, Raphael F., Yotnda, Patricia, Mei, Zhuyong, Dotti, Gianpietro, Rill, Donna, Hurwitz, Richard, Marini, Frank, Andreeff, Michael, Brenner, Malcolm K.

Journal:

Human Gene Therapy

Year:

2001

Language:

english

File:

PDF, 314 KB

english, 2001

94

Chimeric antigen receptor-redirected T cells return to the bench

Geldres, Claudia, Savoldo, Barbara, Dotti, Gianpietro

Journal:

Seminars in Immunology

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

95

Glycolysis determines dichotomous regulation of T cell subsets in hypoxia

Xu, Yang, Chaudhury, Arindam, Zhang, Ming, Savoldo, Barbara, Metelitsa, Leonid S., Rodgers, John, Yustein, Jason T., Neilson, Joel R., Dotti, Gianpietro

Journal:

The Journal of clinical investigation

Year:

2016

File:

PDF, 1.46 MB

2016

96

Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch

Chang, Edmund C, Liu, Hao, West, John A, Zhou, Xiaoou, Dakhova, Olga, Wheeler, David A, Heslop, Helen E, Brenner, Malcolm K, Dotti, Gianpietro

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 2.97 MB

english, 2015

97

Inducible Caspase-9 Selectively Modulates the Toxicities of CD19-Specific Chimeric Antigen Receptor-Modified T Cells

Diaconu, Iulia, Ballard, Brandon, Zhang, Ming, Chen, Yuhui, West, John, Dotti, Gianpietro, Savoldo, Barbara

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.13 MB

english, 2017

98

Combining Oncolytic Viruses with CAR T Cell Therapy

McGrath, Kyle, Dotti, Gianpietro

Journal:

Human Gene Therapy

Year:

2020

File:

PDF, 744 KB

2020

99

Negative selection of peripheral blood stem cells to support a tandem autologous transplantation programme in multiple myeloma

Anna Maria Barbui, Monica Galli, Gianpietro Dotti, Nadia Belli, Gianmaria Borleri, Giovanna Gritti, Piermario Bellavita, Piera Viero, Benedetto Comotti, Tiziano Barbui, Alessandro Rambaldi

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

100

CD19-CAR Trials

Ramos, Carlos A., Savoldo, Barbara, Dotti, Gianpietro

Journal:

The Cancer Journal

Year:

2014

Language:

english

File:

PDF, 148 KB

english, 2014

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