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51

Stratification of non-small cell lung cancer patients for therapy with epidermal growth factor receptor inhibitors: the EGFR fluorescence in situ hybridization assay

Marileila Varella-Garcia

Journal:

Diagnostic Pathology

Year:

2006

Language:

english

File:

PDF, 622 KB

english, 2006

52

Preclinical Studies of Gemcitabine and Trastuzumab in Breast and Lung Cancer Cell Lines

Fred R. Hirsch, Barbara Helfrich, Wilbur A. Franklin, Marileila Varella-Garcia, Daniel C. Chan, Paul A. Bunn Jr.

Journal:

Clinical Breast Cancer

Year:

2002

Language:

english

File:

PDF, 118 KB

english, 2002

53

Diagnostic assays for identification of anaplastic lymphoma kinase-positive non-small cell lung cancer

Weickhardt, Andrew J., Aisner, Dara L., Franklin, Wilbur A., Varella-Garcia, Marileila, Doebele, Robert C., Camidge, D. Ross

Journal:

Year:

2013

Language:

english

File:

PDF, 332 KB

english, 2013

54

Genetic stability of bone marrow-derived human mesenchymal stromal cells in the Quantum System

Jones, Mark, Varella-Garcia, Marileila, Skokan, Margaret, Bryce, Steven, Schowinsky, Jeffrey, Peters, Rebecca, Vang, Boah, Brecheisen, Michelle, Startz, Thomas, Frank, Nathan, Nankervis, Brian

Journal:

Year:

2013

Language:

english

File:

PDF, 3.40 MB

english, 2013

55

Androgen Receptor CAG Repeat Length and TMPRSS2:ETS Prostate Cancer Risk: Results From the Prostate Cancer Prevention Trial

Figg, William D., Chau, Cindy H., Price, Douglas K., Till, Cathee, Goodman, Phyllis J., Cho, Yonggon, Varella-Garcia, Marileila, Reichardt, Juergen K.V., Tangen, Catherine M., Leach, Robin J., van Bok

Journal:

Year:

2014

Language:

english

File:

PDF, 279 KB

english, 2014

56

Chromosomal Abnormalities in Non-Small Cell Lung Carcinomas and in Bronchial Epithelia of High-Risk Smokers Detected by Multi-Target Interphase Fluorescence in Situ Hybridization

Santos Romeo, Maura, Sokolova, Irina A., Morrison, Larry E., Zeng, Chan, Barón, Anna E., Hirsch, Fred R., Miller, York E., Franklin, Wilbur A., Varella-Garcia, Marileila

Journal:

The Journal of Molecular Diagnostics

Year:

2003

Language:

english

File:

PDF, 573 KB

english, 2003

57

Síndrome de deleção 22q11 e cardiopatias congênitas complexas

Machado Rosa, Rafael Fabiano, Trevisan, Patrícia, Koshiyama, Dayane Bohn, Pilla, Carlo Benatti, Gazzola Zen, Paulo Ricardo, Varella-Garcia, Marileila, Paskulin, Giorgio Adriano

Journal:

Revista da Associação Médica Brasileira

Year:

2011

File:

PDF, 460 KB

2011

58

22q11.2 deletion syndrome and complex congenital heart defects

Machado Rosa, Rafael Fabiano, Trevisan, Patrícia, Koshiyama, Dayane Bohn, Pilla, Carlo Benatti, Gazzola Zen, Paulo Ricardo, Varella-Garcia, Marileila, Paskulin, Giorgio Adriano

Journal:

Revista da Associação Médica Brasileira (English Edition)

Year:

2011

Language:

english

File:

PDF, 90 KB

english, 2011

59

A 2.5-Mb physical map within 3p21.1 spans the breakpoint associated with greig cephalopolysyndactyly syndrome

Gemmill, Robert M., Varella-Garcia, Marileila, Smith, David I., Erickson, Paul, Golembieski, William, Miller, York, Coyle-Morris, Jane, Tommerup, Neils, Drabkin, Harry A.

Journal:

Year:

1991

Language:

english

File:

PDF, 4.03 MB

english, 1991

60

Part 1 || Characterization of a New Human Glioblastoma Cell Line That Expresses Mutant P53 and Lacks Activation of the PDGF Pathway

Ruth A. Gjerset, Habib Fakhrai, Daniel L. Shawler, Sally Turla, Oliver Dorigo, Amita Grover-Bardwick, Dan Mercola, Shu-Fen Wen, Heli Collins, Hong Lin, Marileila Varella Garcia, Carol A. Kruse, Ivor R

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1995

Language:

english

File:

PDF, 632 KB

english, 1995

61

Role of hypocalcemia in identification of 22q11 deletion syndrome among patients with congenital heart defects

de Mattos, Vinicius Freitas, Sulczinski, Leonardo Paludo, Milner, Olga Gaio, da Silva, Filipe Augusto, de Moraes, Samir Abou Ghaouche, Trevisan, Patrícia, Fiegenbaum, Marilu, Varella-Garcia, Marileila

Journal:

International Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

62

Congenital heart disease in Southern Brazil: Potential impact and prevention

da Silva, Juliane Nascimento, Trevisan, Patrícia, Guimarães, Victória Bernardes, Zen, Tatiana Diehl, da Rosa, Ernani Bohrer, Silveira, Daniélle Bernardi, Varella-Garcia, Marileila, Paskulin, Giorgio A

Journal:

International Journal of Cardiology

Year:

2015

Language:

english

File:

PDF, 191 KB

english, 2015

63

Human Pulmonary Chimerism after Hematopoietic Stem Cell Transplantation

Suratt, Benjamin T., Cool, Carlyne D., Serls, Amanda E., Chen, Lin, Varella-Garcia, Marileila, Shpall, Elizabeth J., Brown, Kevin K., Worthen, G. Scott

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2003

Language:

english

File:

PDF, 290 KB

english, 2003

64

Demographic studies in a Brazilian population of Arabian origin

Varella‐Garcia, Marileila

Journal:

Biodemography and Social Biology

Year:

1976

Language:

english

File:

PDF, 360 KB

english, 1976

65

Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

Kris, Mark G., Johnson, Bruce E., Berry, Lynne D., Kwiatkowski, David J., Iafrate, A. John, Wistuba, Ignacio I., Varella-Garcia, Marileila, Franklin, Wilbur A., Aronson, Samuel L., Su, Pei-Fang, Shyr,

Journal:

JAMA The Journal of the American Medical Association

Year:

2014

Language:

english

File:

PDF, 462 KB

english, 2014

66

Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy

Despierre, Evelyn, Vergote, Ignace, Anderson, Ryan, Coens, Corneel, Katsaros, Dionyssios, Hirsch, Fred R., Boeckx, Bram, Varella-Garcia, Marileila, Ferrero, Annamaria, Ray-Coquard, Isabelle, Berns, El

Journal:

Targeted Oncology

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

67

HER2 Mutation and Response to Trastuzumab Therapy in Non–Small-Cell Lung Cancer

Cappuzzo, Federico, Bemis, Lynne, Varella-Garcia, Marileila

Journal:

Boston Medical and Surgical Journal

Year:

2006

Language:

english

File:

PDF, 446 KB

english, 2006

68

Biologic and Genetics Aspects of Chagas Disease at Endemic Areas

Bellini, Marilanda Ferreira, Silistino-Souza, Rosana, Varella-Garcia, Marileila, de Azeredo-Oliveira, Maria Tercília Vilela, Silva, Ana Elizabete

Journal:

Journal of Tropical Medicine

Year:

2012

Language:

english

File:

PDF, 539 KB

english, 2012

69

Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium

Villaruz, Liza C., Socinski, Mark A., Abberbock, Shira, Berry, Lynne D., Johnson, Bruce E., Kwiatkowski, David J., Iafrate, A. John, Varella-Garcia, Marileila, Franklin, Wilbur A., Camidge, D. Ross, S

Journal:

Year:

2015

Language:

english

File:

PDF, 212 KB

english, 2015

70

Chromosomal Aneusomy in Bronchial High-Grade Lesions Is Associated with Invasive Lung Cancer

Jonsson, Steinn, Varella-Garcia, Marileila, Miller, York E., Wolf, Holly J., Byers, Tim, Braudrick, Sarah, Kiatsimkul, Porntip, Lewis, Marina, Kennedy, Timothy C., Keith, Robert L., Bjornsson, Johanne

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2008

Language:

english

File:

PDF, 422 KB

english, 2008

71

Spectral Karyotyping Detects Chromosome Damage in Bronchial Cells of Smokers and Patients with Cancer

Varella-Garcia, Marileila, Chen, Lin, Powell, Roger L., Hirsch, Fred R., Kennedy, Timothy C., Keith, Robert, Miller, York E., Mitchell, John D., Franklin, Wilbur A.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 460 KB

english, 2007

72

Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression

Xu, Xu-Zhi, Garcia, Marileila Varella, Li, Tian-yu, Khor, Li-Yan, Gajapathy, R Sujatha, Spittle, Cindy, Weed, Scott, Lessin, Stuart R, Wu, Hong

Journal:

Modern Pathology

Year:

2010

Language:

english

File:

PDF, 630 KB

english, 2010

73

ALK Gene Rearrangements: A New Therapeutic Target in a Molecularly Defined Subset of Non-small Cell Lung Cancer

Solomon, Benjamin, Varella-Garcia, Marileila, Camidge, D Ross

Journal:

Journal of Thoracic Oncology

Year:

2009

Language:

english

File:

PDF, 190 KB

english, 2009

74

Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience

Sholl, Lynette M., Aisner, Dara L., Varella-Garcia, Marileila, Berry, Lynne D., Dias-Santagata, Dora, Wistuba, Ignacio I., Chen, Heidi, Fujimoto, Junya, Kugler, Kelly, Franklin, Wilbur A., Iafrate, A.

Journal:

Journal of Thoracic Oncology

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

75

HER2 Amplification and HER2 Mutation Are Distinct Molecular Targets in Lung Cancers

Li, Bob T., Ross, Dara S., Aisner, Dara L., Chaft, Jamie E., Hsu, Meier, Kako, Severine L., Kris, Mark G., Varella-Garcia, Marileila, Arcila, Maria E.

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 583 KB

english, 2016

76

Chromosomal and genomic changes in lung cancer

Varella-Garcia, Marileila

Journal:

Cell Adhesion & Migration

Year:

2010

Language:

english

File:

PDF, 1022 KB

english, 2010

77

An activating KIT mutation induces crizotinib resistance in ROS1 positive lung cancer

Dziadziuszko, Rafal, Le, Anh T., Wrona, Anna, Jassem, Jacek, Camidge, D. Ross, Varella-Garcia, Marileila, Aisner, Dara L., Doebele, Robert C.

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 4.99 MB

english, 2016

78

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

Zhang, Liping, Yu, Hui, Badzio, Andrzej, Boyle, Theresa A., Schildhaus, Hans-Ulrich, Lu, Xian, Dziadziuszko, Rafal, Jassem, Jacek, Varella-Garcia, Marileila, Heasley, Lynn E., Kowalewski, Ashley A., E

Journal:

Journal of Thoracic Oncology

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

79

EGFR Amplification in Lung Cancer

Cappuzzo, Federico, Hirsch, Fred R., Bunn, Paul A., Franklin, Wilbur A., Varella-Garcia, Marileila

Journal:

Year:

2016

Language:

english

File:

PDF, 8.25 MB

english, 2016

80

Correlation of EGFR-expression with safety and efficacy outcomes in SQUIRE: a randomized, multicenter, open-label, phase III study of gemcitabine-cisplatin plus necitumumab versus gemcitabine-cisplatin alone in the first-line treatment of patients with stage IV squamous non-small cell lung cancer

Paz-Ares, L., Socinski, M. A., Shahidi, J., Hozak, R. R., Soldatenkova, V., Kurek, R., Varella-Garcia, Marileila, Thatcher, N., Hirsch, F. R.

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 916 KB

english, 2016

81

Unusual Chemosensitivity of Advanced Bronchioalveolar Carcinoma after Gefitinib Response and Progression: A Case Report

Dziadziuszko, Rafal, Siemiątkowska, Anna, Limon, Janusz, Rzyman, Witold, Jassem, Jacek, Bunn, Paul A., Varella-Garcia, Marileila, Hirsch, Fred R.

Journal:

Journal of Thoracic Oncology

Year:

2007

Language:

english

File:

PDF, 446 KB

english, 2007

82

Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non–Small-Cell Lung Cancer

Peled, Nir, Palmer, Gary, Hirsch, Fred R., Wynes, Murry W., Ilouze, Maya, Varella-Garcia, Marileila, Soussan-Gutman, Lior, Otto, Geoff A., Stephens, Philip J., Ross, Jeffrey S., Cronin, Maureen T., Li

Journal:

Journal of Thoracic Oncology

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

83

Identifying the appropriate FISH criteria for defining MET copy number driven lung adenocarcinoma through oncogene overlap analysis

Noonan, Sinéad A., Berry, Lynne, Lu, Xian, Gao, Dexiang, Barón, Anna E., Chesnut, Patrick, Sheren, Jamie, Aisner, Dara L., Merrick, Dan, Doebele, Robert C., Varella-Garcia, Marileila, Camidge, D. Ross

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 800 KB

english, 2016

84

Erratum to: Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy

Despierre, Evelyn, Vergote, Ignace, Anderson, Ryan, Coens, Corneel, Katsaros, Dionyssios, Hirsch, Fred R., Boeckx, Bram, Varella-Garcia, Marileila, Ferrero, Annamaria, Ray-Coquard, Isabelle, Green, Jo

Journal:

Targeted Oncology

Year:

2016

Language:

english

File:

PDF, 244 KB

english, 2016

85

Extracellular Signal-Regulated Kinase Activates Topoisomerase IIα through a Mechanism Independent of Phosphorylation

Shapiro, Paul S., Whalen, Anne M., Tolwinski, Nicholas S., Wilsbacher, Julie, Froelich-Ammon, Stacie J., Garcia, Marileila, Osheroff, Neil, Ahn, Natalie G.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.96 MB

english, 1999

86

Macrothrombocytopenia as diagnosis predictor of 22q11 deletion syndrome among patients with congenital heart defects

Trevisan, Patrícia, Barbosa, Sílvia, Sperotto, Graziela, Costi, Caroline, de Omena Filho, Reinaldo L., Silva, Alessandra P. da, Varella-Garcia, Marileila, Fiegenbaum, Marilu, Rosa, Rafael F. M., Zen,

Journal:

American Journal of Medical Genetics Part A

Year:

2015

Language:

english

File:

PDF, 398 KB

english, 2015

87

A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer

Arcaroli, John J., Tai, W.M., McWilliams, Ryan, Bagby, Stacey, Blatchford, Patrick J., Varella-Garcia, Marileila, Purkey, Alicia, Quackenbush, Kevin S., Song, Eun-Kee, Pitts, Todd M., Gao, Dexiang, Li

Journal:

International Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 719 KB

english, 2016

88

Malignancy Detection by Molecular Cytogenetics in Clinically Normal Mucosa Adjacent to Head and Neck Tumors

Barrera, José E., Ai, Hong, Pan, Zhaoxing, Meyers, Arlen D., Varella-Garcia, Marileila

Journal:

Archives of Otolaryngology - Head and Neck Surgery

Year:

1998

Language:

english

File:

PDF, 270 KB

english, 1998

89

Receptor Expression, Cytogenetic, and Molecular Analysis of Six Continuous Human Glioma Cell Lines

Carol A. Kruse, Marileila Varella-Garcia, Bette K. Kleinschmidt-Demasters, Geoffrey C. Owens, Elaine B. Spector, Habib Fakhrai, Elena Savelieva and Bertrand C. Liang

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1998

Language:

english

File:

PDF, 902 KB

english, 1998

90

EGFR and HER2 Genomic Gain in Recurrent Non-small Cell Lung Cancer After Surgery: Impact on Outcome to Treatment with Gefitinib and Association with EGFR and KRAS Mutations in a Japanese Cohort

Varella-Garcia, Marileila, Mitsudomi, Tetsuya, Yatabe, Yashushi, Kosaka, Takayuki, Nakajima, Eiji, Xavier, Ana Carolina, Skokan, Margaret, Zeng, Chan, Franklin, Wilbur A., Bunn, Paul A., Hirsch, Fred

Journal:

Journal of Thoracic Oncology

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

91

Waxing and Waning of MET Amplification in EGFR-Mutated NSCLC in Response to the Presence and Absence of Erlotinib Selection Pressure

Womack, Joel P., Varella-Garcia, Marileila, Camidge, D. Ross

Journal:

Journal of Thoracic Oncology

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

92

An anaplastic lymphoma kinase (ALK) immunohistochemistry negative but fluorescence in situ hybridization (FISH) positive lung adenocarcinoma is resistant to Crizotinib

Shi, Ruoshi, Varella-Garcia, Marileila, Li, Ming, Ludkovski, Olga, Danesh, Arnavaz, Ng, Christine, Pham, Nhu-An, Pugh, Trevor, Shepherd, Frances A., Tsao, Ming-Sound

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

93

Responses to crizotinib can occur in high level MET-amplified non-small cell lung cancer independent of MET exon 14 alterations: A brief report

Caparica, Rafael, Yen, Cheng Tzu, Coudry, Renata, Ignatius Ou, Sai-Hong, Varella-Garcia, Marileila, Camidge, D. Ross, de Castro, Gilberto

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 342 KB

english, 2016

94

Atypical Negative ALK Break-Apart FISH Harboring a Crizotinib-Responsive ALK Rearrangement in Non–Small-Cell Lung Cancer

Ren, Shengxiang, Hirsch, Fred R., Varella-Garcia, Marileila, Aisner, Dara L., Boyle, Theresa, Zhou, Caicun, Camidge, D. Ross

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 926 KB

english, 2014

95

In vivo and in vitro evaluation of betanine mutagenicity.

Conforti-Froes, Nivea, Varella-Garcia, Marileila, Manzato, Antonio Jose

Journal:

Year:

1990

Language:

english

File:

PDF, 329 KB

english, 1990

96

NIH Public Access to Select Targeted Drugs

Kris, Mark G, Johnson, Bruce E, Berry, Lynne D, Kwiatkowski, David J, Iafrate, a John, Wistuba, Ignacio I, Varella-garcia, Marileila, Wilbur, a, Aronson, Samuel L, Su, Pei-fang, Shyr, Yu, Ross, D, Seq

Year:

2014

Language:

english

File:

PDF, 387 KB

english, 2014

97

NIH Public Access

Flaig, Thomas W, Wilson, Shandra, Bokhoven, Adrie Van, Varella-garcia, Marileila

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

98

Anaplastic Lymphoma Kinase Gene Rearrangements in Non-small Cell Lung Cancer are Associated with Prolonged Progression-Free Survival on Pemetrexed

Camidge, D. Ross, Kono, Scott A., Lu, Xian, Okuyama, Sonia, Barón, Anna E., Oton, Ana B., Davies, Angela M., Varella-Garcia, Marileila, Franklin, Wilbur, Doebele, Robert C.

Journal:

Journal of Thoracic Oncology

Year:

2011

Language:

english

File:

PDF, 175 KB

english, 2011

99

Tolerable and Effective Combination of Full-Dose Crizotinib and Osimertinib Targeting MET Amplification Sequentially Emerging after T790M Positivity in EGFR- Mutant Non–Small Cell Lung Cancer

York, Emily R., Varella-Garcia, Marileila, Bang, Tami J., Aisner, Dara L., Camidge, D. Ross

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 638 KB

english, 2017

100

MTE28.02 Implementation of Precision Medicine in Routine Practice: The Latin American Experience

Varella-Garcia, Marileila

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 155 KB

english, 2017